Aldol Addition Reactions, Intramolecular Aldol Condensation Reactions, Retro Aldol & Cross Aldol Rea

[@TheOrganicChemistryTutor]

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Y'all do this in your bachelor's?? Lmao here we do this in 11th grade

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The best video for Aldol Condensation I found on this entire platform Thanks

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I was struggling with understanding the mechanism of aldol addition, but now I have a much better grasp of the topic. Thank you!

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@@PriyankPatel-ji4en In india , we learn this in high school

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[@TacticalCranberry]

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[@KrishShah28]

2 mins into this video my doubt got cleared , ty

[@alexfrostbound4401]

What happened to the carbon for the final product 14:47? Wonderful video just asking for clarity!

[@tejbeeranand7485]

Yes , there is one carbon missing

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[@sagarus-x4]

Very helpful, thank you.

[@fatimasafari7270]

thank for your brilliant education.but i think in 14:49 the product have to have 6 carbons . please check it

[@tejbeeranand7485]

Not 6 , there should be 5 carbon in total in the final product

[@okayyy-mp8ft]

Thank you so much sir

[@nicksacco5041]

12:22 I thought OH was a bad leaving group. How are you able to get rid of it?

[@Beeetlejoose]

My TA told me that it's because we're in basic conditions, so it's ok if we eliminate the OH. I don't have a better explanation for it, sorry LOL

[@nicksacco5041]

j c np. Thanks for responding, regardless

[@chander.261]

I guess he missed the step in which he protonates the OH to water

[@edwinkaze6676]

Formation of the conjugated double bond system gives extra stability to the molecule.....which is the driving force for that elimination. And like you said OH is a weak leaving group And thus follows E1cb mechanism.

[@juststudy9989]

Ch3- is more basic than OH- so here ch3- is a lot more bad leaving group than oH- so less basicity will be good leaving group

[@KOP-nd6km]

at 14:45, why is there no additional carbon to the right of the double bond in the final products??

[@hannakennedy3720]

He froget to put it there, simple mistake.

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Great Lecture

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Thanks 🥺❤❤❤

[@nostro1940]

I recommend watching the Khan Academy...this guy here skips crucial steps

[@maheshchavan2578]

12:15 doesn't it resonate with upper carbonyl group and and form alcohol on both side

[@Detoro_2001]

thanks this was helpful

[@jesusmrosario-claudio4104]

Thank you once again.

[@TG_TG]

Thank you so much, it's helpfull Video

[@doodoobearlove]

looking forward to see Hunsdiecker reaction mech one day!I been wondering the if its the C=O pi bond or O-Ag's O- attacking Br-Br >

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[@mahmoudhosny1078]

What the reaction of aldol-croton and ester condensation for 2-methyl butanal.

[@juststudy9989]

Good video

[@thobekanokwanda2706]

Thank you

[@AfiaTunchi]

Pls does it form two products or one product

[@faizahanif9515]

Retro synthesis is quite interesting

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you're amazing

[@bernicehayford347]

Very useful piece Thanks but please how are you to locate the alpha and beta positions

[@sambitgarai3195]

Why does the H is attacked by the OH- base in the start of the mechanism , is the H acidic? I don’t understand

[@ingenuity23-yg4ev]

yes the h is acidic as the resultant intermediate is resonance stabilised

[@nostro1940]

3:13 doesnt make sense at all

[@tom_winguill]

cross aldol rea ??

[@carolinaracinoskizanata9556]

Why do we use heat?

[@funnyguydragon]

so OH and H can be removed to get final product. sorry i just watched or studying so its not definite answer

[@sibel9951]

there is one thing that confuses me a lot about aldol condensation reactions, throughout organic chemistry lesson our lecturers taught that OH- is a bad leaving group so we have to hydrogenate it to make it a good leaving group otherwise we cannot make it leave the molecule structure, so i am wondering why in the aldol reactions we do not need to hydrogenate it to separate from the structure? if anyone knows the answer please let me know

[@cdbfmdr6873]

hello have you found an answer yet? -a fellow student with the same question

[@ingenuity23-yg4ev]

usually we say OH- is a bad leaving group and it can only leave when protonated under acidic conditions. but here a carbanion is formed and as we know carbanion is stronger nucleophile than hydroxide so it will push the hydroxide out of the molecule.

[@louisbertin1556]

Alors les PC vous êtes prêts pour les concours ?

[@tomiakinsete1716]

why does the nucleophilic carbon attack the carbonyl instead of the alpha hydrogen?

[@princesscereal4579]

the carbonyl is the electrophilic carbon in this case, which is why it attacks there.

[@Pink_rosie_]

💜💜💜

[@asuntus366]

Does protonation occur b4 the OH leaves in the condensation part or it leaves as OH? Cus I have been taught it's a bad leaving group and therefore will not leave until it's leaving ability in been improved

[@limmuquan4796]

it's under basic conditions so the OH can't really be protonated

[@ingenuity23-yg4ev]

and the reason it leaves is because the carbanion pushes it out, as it's a stronger nucleophile

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W vid

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