Tretinoin Causes Death & Is Banned?

Tretinoin Causes Death & Is Banned? Dermatologist Dr. Dray reacts to ‪@NutritionFactsOrg‬ • Topical Retinoids to R...
Tretinoin Dangers - VA study explained • Tretinoin dangers? VA ...
Retinol in pregnancy • Is Retinol Safe During...
What does retinol do to your skin • Dermatologist Breaks D...
Tretinoin short contact therapy • Short Contact Therapy ...
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#retinol #tretinoin #dermatologist
💜Refereneces
Weinstock MA, Bingham SF, Lew RA, et al; Veterans Affairs Topical Tretinoin
Chemoprevention (VATTC) Trial Group. Topical tretinoin therapy and all-cause mortality. Arch Dermatol. 2009;145(1):18-24.
Katz KA. Topical tretinoin, lung cancer, and lung-related mortality. Arch Dermatol. 2008;144(7):945-946.
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The
effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330(15):1029-1035.
Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination
of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334(18):1150-1155
Wang XD, Liu C, Bronson RT, Smith DE, Krinsky NI, Russell M. Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst. 1999;91(1):60-66.
Rigas JR, Miller VA, Zhang ZF, et al. Metabolic phenotypes of retinoic acid
and the risk of lung cancer. Cancer Res. 1996;56(12):2692-2696.
Rosenberg EW, Skinner RB Jr. Topical retinoids: another piece for the retinoid cigarette-lung cancer puzzle? J Thorac Oncol. 2006;1(7):732.
Liddell FDK. The interaction of asbestos and smoking in lung cancer. Ann Occup Hyg. 2001;45(5):341-356.
Latriano L, Tzimas G, Wong F, Wills RJ. The percutaneous absorption of topically applied tretinoin and its effect on endogenous concentrations of tretinoin and its metabolites after single doses or long-term use. J Am Acad Dermatol. 1997 Mar;36(3 Pt 2):S37-46.
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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this KZbin channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this KZbin channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.

[@barbaramoor391]

I’m 80 years old and been using retinol A I was since 50 years old. I’m still here and have 0 health issues and no wrinkles. Fear not.

[@SueRosalie]

lucky you knowing about it so long ago!

[@stlounsbury]

@Barbara - I’m so glad you found it, I started using it when I was about 30 which was 34 years ago, then I stopped and started back again 1 year ago. I like it and I use 0.05% which seems fine for me. I’ll keep with it too, thanks for letting us know.

[@barbaramoor391]

@@SueRosalie Had adult acne, so it was prescribed for that. First knew it had skin benefits in 1980 so I was 37 using it off snd on for acne.

[@PresidentFlip]

@BARBIE..111if she was 50 when she started it she definitely wasn’t thinking about fertility anymore

[@yukii21518]

There is a guy who got injected with plutonium and he never realized and nor he presented any health symptoms until his very death where he died of cardiac failure super old 😂, and he stills remains and the human who resisted the biggest dosis of radiation.

[@KekeMelCampbell]

Been using Retin A since about 23 yrs of age and now 38. I stopped during my 3 pregnancies but always resumed after breastfeeding. My last pregnancy at 35 was really stressful and I got my first wrinkle on my forehead and was shocked to see it disappear after resuming retin a. I don’t even know how long it took before it went away but the fact that it did speaks to how good this stuff is. And I don’t use it for anti aging. I use it for acne. And in general I don’t think I look anywhere close to almost being 40.

[@notyourtypicalcomment2399]

Did all your kids come out healthy?

[@elettramia6380]

😅Not the forehead wrinkle, I feel your concern at that time, I’m always side eyeing my forehead to make sure it stays in check. Needless to say I don’t want forehead wrinkles. I now use Retinal because my skin just could Not deal with tretinoin

[@rianal.7489]

hii there! could you let me know when did u stop it.. when planning for the pregnancy, or after u found out you got pregnant? im still trying to find articles on what is the correct usage of tret when it comes to pregnancy

[@KekeMelCampbell]

@@rianal.7489 hello definitely talk to your doctor but I stopped when I found out.

[@NC1195_]

What brand did you use and how much does it cost? Can tell me your skin care routine for morning and night especially when you go outside?

[@SN-wi6nn]

I’ve been using tretinoin for 20 years already and I assure you I don’t have any health issues from it! Plus my skin looks amazing

[@Lizeth0102]

How old are you?

[@MsGlamourcat]

Same. I've been using tretinoin for over 25 years and I don't have any health issues and my skin looks amazing.

[@Cryptogally]

Why don’t you have a profile picture?

[@lisa408t]

​@@Cryptogally Jesus, Cindy, really???? My god....grow up

[@lisa408t]

​@@Cryptogallywhy don't YOU have a real photo on YOUR profile????? Go away troll.....

[@alabama.worley]

I just wanted to share that today I went out to run errands, and a gorgeous, incredibly well-put-together woman stopped to compliment my skin. This may sound ridiculous to some, however until very recently it was my most significant insecurity. I am covered in painful psoriasis, which a stranger would never know, and really struggled with acne scarring, sun damage due to a lack of education a few year's ago when beginning to use actives, and mental health issues as a result. My skin is completely transformed now, and Tretinoin has done the heavy lifting (sunscreen too). I learned of the importance of SPF directly from Andrea two year's ago, and have since ensured my kid's have basic routines implemented. All that to say, thank you sincerely.

[@CharlieDontSurf21]

I'm so happy for you. I completely understand why this means a lot to you. what spf do you use? thank you

[@jngmom4105]

Can u share what u use to treat psoriasis? My husband has it and his dermatologist prescribed steroid cream

[@whomppywhompp]

@@jngmom4105 my sister has it, she uses tazarotene and a lot of hydrating cream to keep it under control, and SPF ofc, she also takes vitamin d religiously all year round, so far it's been working for her, my best wishes for your husband

[@mirasingh7428]

Do tretenoin tighten skin?

[@alabama.worley]

@@jngmom4105 The corticosteroids don't help me at all. I've been sent to light therapy beginning in January. I've looked at the research and it's promising.

[@nadzideaz9341]

I got pregnant 4 months during my treatment. I was advised to have an abortion I did 20 scans I was told she had no fingers cleft palate. I still refused she is now 14 years old and is perfect, no abnormalities. The scans were all lies. The only problem I am having with her is her rude attitude, and she is ostentatious

[@maryrotondi213]

😂

[@Rosmadel]

😅

[@vegliving]

You made the right decision to keep the baby, as far as rudeness, although I am not a doctor 😂 , I honestly don’t think that is regaled to RetinA, however they all behave like that at teenager time , hopefully they’ll grow out of it…..happy holidays

[@sweetxjc]

That’s so strange. What kind of doctor lies to get someone to kill their baby?

[@Ihatetravelling]

​@@sweetxjcthe doctor was probably one of those woke feminists who are like i eat babies for breakfast and i will kill my baby whenever i want even if I'm not raped! It's probably one of those extremist activists because they have gone to the extreme,they present abortion as a homicide and one of those literally took some baby dolls and started chewing them like a maniac and that's her way of supporting abortion!They are literally out of control

[@FleurPillager]

Isn't it more important to note that in the hundreds of other studies looking at the effects of tretinoin, an increase in death of participants was not an outcome? Sounds like that study was an anomaly.

[@lukastemberger]

It makes sense though. It's reversing age and when you go back to age zero, you're unalive.

[@alicjaalvena1120]

@@lukastemberger xD

[@shannond818]

When she said the participants were around age 70 and veterans, it made me go “oh, that’s why they’re dying!” I’d be concerned if the study had been on people in their 20’s and they all started dying. Even if they were all dying from different things, if they weren’t dying from accidents, I’d be concerned.

[@src4409]

Or that all the other studies were paid off not to show this affect. Too much vitamin a can cause liver damage.

[@aeducator1]

The other studies were too small and too short to show an impact on death. You need lots of subjects and lots of time.

[@sandrapetro3047]

I started retin A at 18 and I am 61. When I was 18 the tube was huge and $40 and prescribed for cystic acne It works great for that! When I hit 40 I noticed my skin looked youthful so I've kept using it despite the tiny tube and $100 price tag!

[@latinaalma1947]

Thank goodness I am in Latin America $15 for a 6 week supply so worth it to me.

[@cindysmallwood2695]

luckily despite medicare not being the great deal I'd hoped it would be, it covers my Tret. 100%@@latinaalma1947

[@divinesoul1313]

In India price is 1.5-2.5 $ for 50 grams of tube.

[@xassy]

You can get it for $50 generic version, look online pharmacies have different prices. I always ask friends who vacation in Mexico to buy a few tubes for me. The 0.1 costs $30 in Mexico and it lasts me almost 9 months, no prescription require.

[@SueRosalie]

I get mine from India, it's about US$6-10

[@patkern185]

Thank you, Andrea, for being the voice of reason. I know I'm not alone in my trust in your well researched information. I'm glad you noted that the VA study didn't address the participant's manner of death. That was the first question I had. I know Viet Nam veterans whose skin shows the negative effects of Agent Orange and other vets from other conflicts with a host of health issues, as well. As soon as I was able, I watched this video for the facts. Thanks again!! XXOO ❤

[@Portia620]

The government hurt our VETs and want to blame something other than the agent O or other chemicals or magic bullets lately!

[@21972012145525]

​@@Portia620of course they did. They sent them to WAR. They still inflict and enable war on other people. I am praying for the Palestinians

[@josemmz]

The only thing tretinoin has killed is my acne

[@irr35i5tibl3]

OoooKAY!!!

[@theresaaa8346]

😅

[@aprillynch5865]

That part!!! Same here 😂

[@convenienceandpracticality9032]

My son uses Twyneo, which is 0.1% tretinoin & 3% benzoyl peroxide. His dermatologist said it's a slow release tretinoin so the side effects are lessened. He seems to tolerate it really well.

[@DrDrayzday]

yes, much better tolerated!

[@Bea_Rosy]

Is that like Epidio? Adapalene and benzoyl peroxide

[@convenienceandpracticality9032]

@@Bea_Rosy It's stronger. Epiduo is 0.3% adapalene & 2.5% benzoyl peroxide. Tretinoin is stronger than adapalene and there is more benzoyl peroxide in Twyneo.

[@alabama.worley]

You sound like a good mother.

[@convenienceandpracticality9032]

@@alabama.worley You are too kind! Thank you. I suck at being a mom, actually. Haha. But try my best like everyone else.

[@just_plain_shannon]

Thank you Dr.Dray for teaching us & doing all this research to share with us!!! You have been my favorite part of 2020 when I found you & even still to this day!

[@ophelialeverett1]

Great video explaining this study’s findings. I was concerned about this as I follow nutrition facts for health information and learned about this study. I have not used tretinoin in the past because of this. However, I’ve followed other dermatologist’s who have used it for many years, even decades, and remained ‘alive’ doing so. Thank you for shedding some light on this very important issue!

[@KarenGaylor4712]

I think there were some flaws in the study. Dr Jessica Krant, a wfpb dermatologist, said she disagrees with him, but would.love to have a conversation about it. Dr Krant loves Dr Greger.

[@Muskaan7100]

Hey may I please ask what nutrition journals you follow? Thank you M

[@tedoymisojos]

I can't believe he published that video. Its so misleading and insubstantial. Seems like lazy work and that he thinks little of his viewers capacity to fact check.

[@iwillnotseeyourreply.9235]

You want to take health advice from Dr Greger? The man that looks like he died 15 years ago? Lol. Never ever go vegan.

[@cassclare]

Also take wgat dr.greger says abput aging with a grain of salt. He is only 50 and he looks atleast 65. I'm not sure why he feels like the authority on 'how not to age'

[@whomppywhompp]

I've been using tretinoin for years now i even use it under my eyes without irritation, i combine it with lipikar balm at night and during the day before i put my sunscreen i use cicaplast, so far this is the routine that worked best for my skin with great results

[@AyaneBKing]

Same. 0.1 % every day, also under the eyes, just like you. works like a charm. and it's super cheap in Europe too. hate this fear mongering

[@karend.9218]

My daughter doesn’t use it near her eyes but it spread into her eyes and caused profound eye issues and distress. Be careful.

[@SweetUareDesi]

@@karend.9218like what?

[@notaclue822]

I heard that you need to avoid the hairline, lash and brow area because it will cause hair loss. Any truth in that?

[@AyaneBKing]

@@notaclue822 i heard that too, there was a study though where they used minoxidil with tretinoin and it was more efficient than minoxidil alone in treating hair loss. Which would contradict that it causes hair loss . That’s why I was using it on my hairline and brows too, in case it would help with growth 😆 I didn’t notice hair loss and I’m monitoring that closely with a 10x mirror 😆

[@Sentient_Goose]

I'm loving how deep we're going with the science lately, so here for it!

[@carolinaochoa7900]

It’s certainly not banned in Europe, in fact it CAN be bought OTC and it’s cheaper than in the US.

[@SueRosalie]

yes it's otc in Spain

[@vstef5891]

uh, no. not OTC in "europe" . Can't buy it in Norway, Germany, etc. Maybe its OTC in UK and Spain, but many countries in Europe make it very hard to get.

[@AMC66765]

@@vstef5891 it's prescription only in the UK.

[@dawnmarie6302]

I’m so glad you saw this and did a video for us. I saw this last week and was shocked at the end. It scared me because I just started using Tretinon.

[@kathysharp7551]

Me too!! I start tret in a few days. I saw Dr. Greger's video and thought "This is far outside his area of expertise. Strange he would make such a bold statement. I love Dr. Gregor's nutrition info, so my emotions tell me to believe him. But, my mind says wait a minute. Dr. Dray is the skin expert, and she's never said anything like that. I trust her on this topic." But, I still felt emotionally unsettled until watching this Dr. Dray video 😊 So glad she made this video!

[@thelasttrumpet2915]

Trust Dr Dray. She knows what she’s talking about.

[@kristinek7436]

Excellent critique. I love Dr. Greger, but was very skeptical about the VA study. I am glad you looked into it. Meanwhile, my dermatologist in France prescribes tretinoin at about $15 a tube.

[@smushface3999]

He said “banned for cosmetic purposes”, because it’s not available over the counter in cosmetics. While I think he needed to go into more detail in the last minute of the video, she is cherry-picking half of what he said and sensationalizing it as something else

[@21972012145525]

​@@smushface3999isn't this a reaction video? Is this not the whole video?

[@anaverran3040]

I really appreciate your explanation of the findings from these scientific studies.

[@anonymousa-uy1hk]

Phew! You had me worried there for a second thinking Tretinoin was going to get banned! I’ve heard of the study mentioned by Dr. Greger and I still continue to use the product. It’s worked wonders for me. I’m not worried and will continue to use for the rest of my life.

[@sebastianciuca7463]

I find it irresponsible to dismiss a study which finds a 50% increase chance of dying in the tretinoin group. A lot of people here are giving anecdotes - but just because it is not harmful to you, it doesn’t mean it won’t be for others. For example, most people aren’t allergic to peanuts - but for some, ingesting a small amount can be deadly (e.g. anaphylactic shock). It is no surprise that the body degrades faster with age. Comparing this study with other ones which are observing younger people is not really relevant. What would truly be relevant is looking at how those young people’s health evolves when they’re in their 70s if they keep using tretinoin. Of course, those who die can’t really come back and tell the cautionary tale. Also, the study looks at men, so mortality might also be linked to the way in which men particularly metabolize the absorbed tretinoin. Furthermore, as the doctor suggests, the mortality might also be linked to other behaviors, such as smoking. Again, it’s incredibly important to use this study as a “watch out, if you smoke, tretinoin might have grave side effects”. Yes, we don’t really know what caused the tretinoin group elderly men to die. But for the reasons mentioned above, dismissing this fact as a coincidence, especially when there’s is just a 1% chance of this statistically being a coincidence (as the study mentions), is gravely irresponsible.

[@21972012145525]

She basically said that imo. Although neither Dr explained the 50% increase you're referring to imo

[@SueRosalie]

sorry but you can't make any of those assumptions that you are making up. This study was full of flaws, there is no point going any further. Maybe you should get some training in basic stats and research you you understand a bit about how evidence and inferential statistics works.

[@SueRosalie]

and further, we have over 50 years solid data on the safety of tret already. That's 45 years beyond the standard time frame of long term safety studies.

[@CuteCatsofIstanbul]

I love Dr. Greger, he and his team are experts at looking at studies and explaining things for us - however I do agree that instead of only saying 'it is banned in cosmetic products (you buy in a store)' and ending there, they should've also mentioned it is available as prescription only.

[@keekeejenkins6162]

No, it's because they didn't bother verifying the information. Which is worrisome for folks who trust them to do so.

[@CuteCatsofIstanbul]

@@keekeejenkins6162 It wasn't lack of verification - it is banned in cosmetic products.

[@FleurPillager]

@@keekeejenkins6162 It's completely misleading. I don't trust the information on that channel at all.

[@grat2010]

It's misleading, which says a lot about the kind of information they provide. Dodgy.

[@Pubslife]

Love Dr Gregor!

[@jrmint2]

Thank you Dr. Dray for teasing out the fine points that are important to understand the positives and negatives that Dr. Gregor covered. While I overall enjoy his videos and overall find them helpful, I feel his coverage into so many areas leaves him pretty much an interpreter of studies, rather than an expert in those areas and I often feel that his agenda to push a plant based diet, w no supplements skews the way he presents info. I wonder what his coverage on collagen supplements will be as I have not read his latest book. I always enjoy your videos and you are a treasure amongst peers covering skin science and products on youtube. I love how deep your coverage goes. ❤

[@RK-su4hs]

as you mentioned Griegor reads studies only He does not refer to his own findings by virtue of his work with patients Adds little as medical studies can be accessed & read via google “experience is the only real knowledge “ Albert Einstein

[@21972012145525]

​@@RK-su4hs that would be anecdotal evidence if he referred to his own patients, not scientific

[@conservativegirl3371]

I’m not sure if it causes death, but after using tretinoin for many years it started causing me severe headaches, neck pain/stiffness and back pain….I’ve tried many times and yes, it is caused by the tretinoin…even retinol after a week or so. So I’ve given up on using it. I use peptides, glycolic acid, and all the other things. Hydration, ceramides, and peptides and have made my skin look pretty good. I feel healthier not using tretinoin. Just my experience. Drs are very hesitant to admit to negative side effects. I know it can cause intercranial hypertension based on one paper in medical journal. Not everything is good for everyone.

[@user-wd3po8sd7k]

I got extreme dizziness from it.

[@Robin-gf7bd]

I have the same problem with Tretinoin and even OTC retinol and retinoids. I keep going back to it bc of how great it is for anti-aging, but the headaches are so debilitating that I have to stop again. And I’m at that point now. Just barely at the stop peeling point, and now have to stop again.

[@cocobleu2990]

Works great for my skin, but also gives me severe headaches and stiff neck. The same thing happens with Minocycline or any Tetracycline antibiotics.

[@hurainejaz7472]

Same problem I got from trtinoin .even it was good on skin but it spread toxication in body

[@sparkleupdate]

I had severe back pain from tretinoin too. I stopped using my skincare the first time, the backpain started, started again with my skincare when I felt better and d backpain came back, still didn't know it was what caused it until I saw a KZbinr talked about it and entirely now stopped tretinoin, now no more backpain, it was so great for my skin, I really wished it wasn't toxic for my body.

[@debrabaker6021]

I’m 65 y.o. and have used tretinoin since I turned 40. No problems and great skin.

[@SueRosalie]

I wish I had started at 40 like you, but it's never too late. Just 2 years in and my skin is dramatically improved.

[@lynnwalker]

Thanks Dr. Dray! Love your detailed and science backed explanations. I'll keep using my Retin-A 😉

[@palakush7650]

Your one like comment saved me 20 minutes cause I understand moral of the video is to keep using retina

[@21972012145525]

​@@palakush7650you can adjust playback in KZbin

[@catherinelynnfraser2001]

Thank you for going over this so carefully

[@GladBurgio]

I'm an American living in Sicily and use tretinoin by prescription. Obviously, it's not "banned." The price is much, much lower here at $20. No surprise!

[@brianne_84]

It depends on where you buy it. I paid $30 at the Walmart pharmacy for a 45gram tube of Retin-A using GoodRX. But yeah, there are websites here charging $90 for a 20 gram tube of generic tretinoin, which is outrageous.

[@GladBurgio]

@@brianne_84 good to know!

[@leticialove1176]

Dear Dr. Dray you have the scientific knowledge🙏🏼❤️. I don’t trust people coming up with stories to scare us. GOD BLESS YOU DR DRAY✝️

[@thanosfield2642]

Tretinoin and retinols sure do help and great for numerous cases. 😊❤

[@lyramed]

Love and following both for many years. Love how Doctor Greger contrast and compare papers, much of his information is very useful ❤ but ever is good to know the expert part. Thanks Dra. Dray ❤😊

[@Flyonthewall101yes]

Thank you so much for this video. It was very informative. God bless you and your family. Keep up the good work

[@Lex.Lee.]

I was so hoping you would talk about this!!

[@DrDrayzday]

thanks for watching

[@billytothe6thpower]

I'm 114 and been using it for the past 25 years

[@davidgoward1711]

I was so excited to see that you made these two videos. Thanks Dr Dray!

[@bigbeautifulsky]

I find that Dr. Gregor often cherry-picks biased data to make him and his theories look credible. As a nutritionist, I don't recommend a vegan diet for menstruating women. As for Retinoids, I've been using them for years, and I'm fine; I get bloodwork often. And I do not smoke or drink alcohol. I did try a vegan diet for two years, and I became severely iron deficient, had terrible acne and was bloated and miserable. I also developed severe PMS and hormonal imbalances. According to my bloodwork, I was unhealthier as a vegan than a meat-eater and I ate the "right" foods (beans, nuts, veg, etc). Some people don't tolerate eating anything but beans, nuts and vegetables as those foods can cause more inflammation than a diet containing meat (gut health is better with meat for me). I thrive on meat, collagen and Retin-A. Guilt and shame-free :) Thanks Dr Dray.

[@juliabinford6500]

Thank you for sharing the nuances of research. I wish there would be more studies related to tretanoin for prevention of skin cancers. My father has to go every 4 months to get these removed from his face and arms. I’m trying to avoid that. I do use sun protection, but I didn’t know what I know now when younger.

[@manyblessings917]

Does your father take any statins? If yes, this may be related to his skin cancer. As soon as my bro in law stopped his statins his skin cancer stopped.

[@nadiamccall4311]

There is fluouracil cream prescribed specifically for skin cancers that some patients take home (they must be compliant and diligent at using it correctly.) It will burn the cancer off (in place of having a doctor laser or burn it off.) When it comes to tretinoin for skin cancer prevention, I don't know that this would be a good idea. I had thought this briefly, but when you read about how it works and what genes it targets, it would not help with keratoses. When it comes to cancer you don't want to help it make new, you want to end it. Not sure if that makes sense

[@21972012145525]

​@@nadiamccall4311 tretinoin is supposed to help prevent skin cancer I believe

[@SueRosalie]

@@manyblessings917 1 anecdote doesn't mean anything

[@manyblessings917]

@@SueRosalie go look it up...one example in the Journal of the American Academy of Dermatology.

[@kekoakaawa8879]

I think that anything we put in or on our bodies has the potential to affect us systemically in negative and or positive ways. While tretinoin may be generally recognized as safe and well tolerated by the general public, I think there are people, like myself who experience bad side effects from it. Every time I have tried tretinoin or retinol, even at lower strengths, I have had side effects of depression and some muscle pain. I found out from my doctor that I am a slow metabolizer, so it seems my body is really good at holding on to chemicals or ingredients that it comes into contact with, which can cause a build up and the I get symptoms from having an excess of that material. To summarize- even if it works for many there could be a small percentage of people who will experience negative effects. Edit: Tretinoin is a derivative of vitamin A. Vitamin A is a fat soluble vitamin, so the body will hold on to it longer; and there are side effects to having too much vitamin A in the system such as depression etc.

[@sparkleupdate]

True, I really wanted this to work for me but it gave me severe back pain, I stopped, the backpain left, I tried tretinoin again the severe back pain started again, I just knew it was it, until I saw someone also made a video of it causing headaches, backpain etc.. But now am getting this from u it could be slow metabolism, I think I have that too... Wow

[@ra-wj1wl]

You’re not alone. My sister is on the same and she has horrible, HORRIBLE body aches, so bad that she cant even move but she’s not ready to give that up cause thats the only thing working on her acne. Rt now she is going through multiple blood tests to check whether she might have smoe under lying issue aggravating the pain.

[@21972012145525]

Did the Dr measure your vit a levels? It seems that too much vit a can be easily diagnosed with a lab test

[@meshelle_kimeko]

I have been using tretinoin for a couple of years after watch several video from Dr. Dray and it is one of the main ways I keep my acne under control. Without it my acne is aggressive and painful. It sucks that I have to jump through hoops to get it prescribed. 😢

[@Realalma]

That’s not ok. Have you tried an online pharmacy?

[@21972012145525]

What hoops? If you have severe acne you shouldn't have to as it's first line treatment

[@Somayeh27]

I started using 0.05% tretinoin cream six months ago, initially applying it once a week and gradually increasing to twice a week. However, each time I applied the cream, I woke up with a headache. Despite this, I continued, taking paracetamol to manage the discomfort. When I tried using it every other night, I experienced the worst headache of my life for ten consecutive days. The pressure on the back of my head and around my eyes was unbearable. Since discontinuing the use of tretinoin, I haven't experienced any headaches.

[@MoGeeinternationalsince1969]

He needs to stay in his lane…not a board certified dermatologist’s lane! Dr Dray is an expert.

[@leticialove1176]

I retired from VA as PMHNP-BC… research is commonly poorly done in this Federal organization 🔄🔁

[@UrsaBella]

most research probably paid for by the manufacturers...even if not explicitly obvious initially... data can lie...or can and have always been used to lie.

[@21972012145525]

Examples? Also what is pmhnp bc

[@trinistar1930]

So basicly tretinoin doesnt cause death and is a great option for people with severe acne and textured skin.

[@graceclement5922]

Thank you for the in-depth reporting. It needs to be said that one study is not conclusive especially when there are so many gaps as you pointed out. It's more of a a scientist thinking out loud and not realising the effect it may have.

[@marionayd]

I live in Spain and I can confirm you can buy retinol, retinal and tretinoin. I use an over-the-counter tretinoin called Treclinac, which has 0,025% tretinoin combined with 1% clindamycin. 😊

[@BlueBlossomsBlues]

I think the new EU regulation is for anything over 0.05.

[@thelasttrumpet2915]

I have bought Tretinoin from an online pharmacy in Andorra (Spain) for years. Retirides the product is called. 0,1.

[@marionayd]

Yes! You can buy Retirides in 0.025, 0.05 and 0.1 concentrations. Hope this doesn’t change or I’m in trouble 😂

[@Julia.260]

​@thelasttrumpet2915 i also buy Retirides from them! God bless them for shipping it to other countries. if this will change, im packing up my family and moving to Spain😂😂

[@leanne8005]

How did you know what strength to buy? 😊

[@itsaaronlolz]

I love how your title shows under your name. It’s so cool 🤩 thank you for educating us 🙏🏽

[@samanthaporter6662]

I just got out of the shower and don't plan on going outside today and just applied my tretinoin!

[@Rtyoepndnf4]

It‘s not banned in Europe…lol. You can even buy it in some countries without a prescription…Idk if it is OTC but the pharmacies sell it to you.

[@andie1508]

I'm just going to say that Ive had 7 children and I didnt know any better- I used tret during the pregnancies of the first 5. The last 2 I stopped the tret while I was pregnant and then picked it back up after the babies were born. All babies were healthy and had no issues.

[@roohana]

I buy retin-a without RX from pharmacies in Spain and Portugal. He is so misinformed.

[@toto850]

Been wondering when you would adress this topic.. very informative

[@davidshabas3839]

Happy Friday Dr Dray so excited to be here I live for this ❤️

[@DrDrayzday]

Morning!

[@davidshabas9280]

@@DrDrayzday ❤

[@whitneybrown4067]

Greetings David Shabas hope u r well n Happy Friday😀👍💜….

[@davidshabas9280]

@@whitneybrown4067 Happy Friday Whitney😀👍

[@kamikessel]

Dr. Dray, thank you so so much for this video. I really like and respect Dr. Greger but this video caused him to lose a little bit of credibility with me. I appreciate very much that you provided such a carefully crafted and timely response to the problematic video. I found it uncharacteristic that he would simply end his video talking about death without any context. I looked for follow up videos to provide more information like he usually has and didn't see any. I value your input so much, and you have helped my skin so much during the past few years. Again, thank you!

[@user-vs9qz6ro7z]

So you just will deny evidence when it doesn't fit what you want to hear?

[@21972012145525]

​@@user-vs9qz6ro7zwhat exactly is she denying? He did end the video abruptly

[@AdrianaMontemayor7]

THANK U SO MUCH FOR UR WONDERFUL WORK DOCTOR ❤ BLESSINGS ALL THE WAY FROM MONTERREY MÉXICO ✝️

[@meggieprice]

Therapy day- need a Dr. Dray for soothing! 💜💜💜

[@livchesy6007]

Thanks for this clarification. It completely freaked me out when I heard “death”

[@glendagai]

What a blessing you are to social media. Your clinical training and knowledge are so very needed.

[@carolwong9279]

I love Dr. Greger, but I did not agree with his presentation. Vets have so many health issues that it's very difficult to link trentinoin to death. I am so glad you made this video. I am 64 years old and have used Tretinoin for over 20 years and it has made a significant beneficial impact on my skin. I will continue to use Tretinoin.

[@Jaimyx77]

I've been using tretinoin for 5 years now, I started when I was 20. I've have noticed that irritation starts when you reached the point when your skin is starting to dry, It begins to itch and sting also some redness. But after adding and mixing Hyaluronic Acid, I noticed that I am no longer irritated, and my face is plumped when I wake up. The only skin Care I use is Tretinoin, Hyaluronic Acid and Niacinamide. I only wash my face with soap and some cleanser after. And ( I don't have an acne, I just use it) I believe they are banning it because it is easily misused especially if you don't know how to use it. People should watch these doctor created videos as well as listen to and learn from their experiences in order to avoid the negative side effects. Tretinoin is a great product, my mom has started using it as well after she sees me using it. Also avoid sunlight. well as an Asian Sun bating culture is not really a thing, we try to avoid sun as much as possible especially 9am-3pm, whenever we come out we always bring umbrella or protective clothes. And what I also noticed is that sunscreen is starting to be a thing right know, but to be honest I don't use them, I just try to avoid the sun. morning exposure to sunlight is enough 6am-8am. I believe too much is bad, moderation and consistency is the key.

[@to4217]

That might be because acids like hyaluronic acid negate and inactivate retinoids according to another dermatologist I listened to on this.

[@21972012145525]

​@@to4217that isn't true. Source?

[@21972012145525]

​@@to4217if anything hyaluronic acid could theoretically increase penetration of retinoids

[@21972012145525]

Irritation happens. It's just hoe it works. If you start getting dry you should reduce frequency and or strength

[@SueRosalie]

it is not being banned anywhere

[@lyno5462]

I've used this for 33 years. Everyone always asks what I do cuz I look younger than my age. No health issues here.

[@stephm4047]

13:26 And ? It is also banned in cosmetics in the US. Retinoic Acid is sold in Europe as a drug, on prescription in France (I know because I live in France and use it and it costs between 4€ to 15€ depending on the brand, so cheap but not covered by health insurance) but OTC at drugstores in some countries such as Spain. Retinol and Retinal are available everywhere OTC including at local supermarkets.

[@8thhousealchemist600]

Whatever, I've been using Tretinion for so many years with zero health problems. I also eat clean and stay away from processed foods and zero meat, sugar, and dairy. Food and nutrition should always be the first place people should look for the stem of the problem.

[@gemanuc2532]

I’m European and I can confirm that it’s not banned, for the time being. You just need a prescription. In some countries like Greece they might give it to you OTC and it’s ridiculously cheap. Also, I heard that the EU is currently considering enforcing restrictions to limit its distribution.

[@jonathan1636]

I have a PhD in Family and Human Development. I have spent all my career--including my training--learning to better consume and conduct scientific research. All this to say, Dr. Dray is here going through a peer-reviewed published study in a dermatology journal, and going through it as the trained scientist she is (I recall she has both a PhD and an MD) for her audience. I certainly applaud her for really democratizing the findings of those in the ivory tower. I promise, she is bringing research findings as they advance with the same critical eye of a trained scientist in a very accessible way. This woman is truly amazing and, on a personal note, of all the "influencers" she is the one that has had a true and palpable impact on the health of my skin and even on that of my family (including my teenage cousin who, at 16 , was suffering from dry skin from chemotherapy). And for that, I am genuinely grateful for Dr. Dray!

[@21972012145525]

The other Dr is credible as well though. What about the reason why they stopped the study though? The 50% increase is still concerning

[@SophiaDerivan]

Everyone in the past who has used it has passed away…eventually, maybe it is the problem!😱 Thank you for the videos!🙌🏽

[@kathysharp7551]

😂 You're funny. Thanks for that 😁

[@kathyjimenez4370]

They would later die from complications caused by Tretinon and since it’s not directly coralated they’ll say it’s due to something else and continue to push product to the masses! No thanks! Don’t need that garbage to look younger rather be healthy and alive! Vanity!

[@sewitseams5632]

😂😂😂

[@21972012145525]

​@@kathyjimenez4370no one is making you use it

[@houserules3302]

I was late to the party and didn't start using Retin-A until I turned 50. I'm 58 now and my wrinkles are gone, my skin is smooth and clear and people say I loo like I'm 40.

[@pamelarodriguez5674]

Fantastic video. I literally burst out laughing when she dryly said, "He really left us on the edge of our seats." 😂

[@emilypaulsen6030]

Appreciate your video on this. I saw him mention the increased risk of all cause mortality in a speech earlier this year and wondered your thoughts!

[@maalikserebryakov]

He should have tried mitigating the all cause mortality of his hair

[@theshunnedBandersnatch]

​@@maalikserebryakov 😂😂😂

[@pnevlud]

Well if tretinoin is killing me, I’ll look good in my casket lol😂. It really does help with aging skin. Been using it for years

[@appalachianfamilyrecipes4647]

I have used Retin-A for 20 years on my face. In the last 5 years I’ve began to use it on my body as well. I have wondered how much is safe for my whole body.

[@21972012145525]

Use retinol on the body instead

[@MOON-Hkr]

My favourite dermatologist Dr Dray. ❤

[@Growstuff70]

Thank you for being a voice of reason.

[@Lalayolo]

This better not be a true title I can’t live without tretinoin😭😭😭 happy holidays Dr Dray!!🎄💖

[@PhenixJoe]

Same! to the extent that I probably would have continued to take my chances even if it were true 😂😂.

[@annhall2331]

My thoughts exactly lol

[@marylawman8603]

Very interesting topic today. I don't think people using Tret have anything to worry about. Happy Friday, Dr Dray! I hope you, your sweet momma and little Tybee have a wonderful weekend. 💖

[@whomppywhompp]

Tretinoin is not banned in Europe at all it's a prescription drug like any other, what is different is the legislation with the cosmetic retinol products, for example in France it's not allowed to put retinol in the packaging as a marketing element, you'll find it in the ingredient list or mentioned in the back of the box but never displayed in the packaging as the main marketing point

[@TheSpeedyone2]

and the % used.......

[@alabama.worley]

Interesting. Ty for sharing.

[@db-gb5xi]

I believe Mo Skin Lab (toxicologist/Italy) has a video on the EU retinol ban.

[@whomppywhompp]

@@db-gb5xi it's not banned it's heavily regulated mainly bc of its effect on pregnancies, but it's still present otc

[@HereDiianas]

The max percentage allowed for face and for the body has changed and it will come into effect within the next 2 years so brands will have time to adjust their production.

[@ematrill3008]

dr dray is the oracle of skincare

[@catthecruisebrat3499]

I buy tretinoin .25% OTC in the pharmacy in Italy every time I am there…last time was this past summer (2023)…definitely not banned in Europe!

[@HereDiianas]

It's because for face the new maximum amount allowed for face is 0.3% and yours in under that new limit. Plus those new rules will take into effect within the next couple of years in order to give brands time to adjust.

[@SueRosalie]

@@HereDiianas um the maximum strength available is 0.10%, you can't get it in 0.30%

[@arlindgjeka226]

I have been using it for more than 15 years my face loves it so much, so other than thinning out my eyebrows I’m very healthy

[@Mixibiti]

Thank you Dr. I really love tretinoin . I have been using it since 2 months and my skin was sensitive on the first 3 weeks but now my skin is beautiful and stick to your advice on how to moisture and sunscreen. Thank you for everything. Big hug from Portugal 🇵🇹

[@katechipata9934]

Did you experience any purging?

[@kyms9390]

Thankyou for your well researched videos, I particularly enjoy the ones with retin A content. I have beeen using prescription Tretinoin 0.05% for years & am thrilled at what it does, I started it gradually, never got redness or peeling, some dryness yes but I use a good moisturiser. I am always shocked that so many women have no idea about it as it really is the best thing for anti aging that you can do at home easily.

[@mimido23]

Thank you for the research. I've been considering it, but I don't think for myself I'd want to deal with any potential side effects. My skin is nice allready and I'll stick to my moisturizer, vaseline, spf and chemical peels.

[@21972012145525]

It's supposed to help collagen and wrinkles too though

[@BradSchoenfailed]

Don’t do it it’s not worth death

[@21972012145525]

@@BradSchoenfailed Did you not watch this video? Vit a topical is basically the only way to increase collagen and reduce wrinkle formation (if you're practicing other healthy behaviors)

[@SueRosalie]

most people get no side effects, including me. Any negatives are hyped up on the internet.

[@SueRosalie]

@@BradSchoenfailed tretinoin has not killed anybody. You know what does? Smoking and skin cancer from sun baking.

[@FixyASMR]

its not banned in europe? I get it prescribed to me easily, and I am in Belgium.

[@LiveIRLViewer]

Crazy crossover I didn't expect! How many years have you been on Tret?

[@claudinehellmuth]

Thank you for such an informative video! Could you talk about Trentinon affecting the lacrimal glands in the eyes? I have dry eye disease and I’m worried that the tretinoin could be making it worse or is that just the Accutane version that affects the lacrimal glands and not the topical? I keep it away from my eye area. Thank you!

[@DrDrayzday]

i have a video on this...it does not cause dry eye disease

[@claudinehellmuth]

@@DrDrayzday oh, thank goodness! Because I love the way my skin looks right now lol. I will search out your video on this topic.❤

[@cassclare]

I can personally say that Altreno has caused me zero irritation, and i used it everyday, since day 1

[@spiderqueen601]

I loved Dr Gregor but now I’m questioning the whole channel!! 😮😭

[@maalikserebryakov]

He couldn’t even safe himself from the Slaphead curse.

[@21972012145525]

​@@maalikserebryakovwhat's that

[@JenniferKBrown]

Very interesting, I’m always grateful when we are given a broad range of information so that we can do our best to make informed decisions. It’s always important to remember the multi-millions to be made off of women’s desire to feel beautiful and ensure that the darlings of our beauty regimes are frequently kept in check for their safe use.

[@SueRosalie]

it's the people who are making millions out of selling useless cosmetic products who are always trying to discredit tretinoin.

[@bluejay5531]

thanks dr. dray ❤ I just started using tretinoin and this was reassuring

[@margieryne6220]

Thank you for sharing this. Have a great weekend!🥰

[@avon1243]

I found this very interesting!

[@lauracuevas8948]

Love this information!!

[@Idk-do4db]

He’s actually annoying to listen to. Sketchy, too. On the upside dr. Dray have you picked up the Christmas cheer candle from target? It smells so nice and warm. I’ve been burning it in my home office. So relaxing!

[@21972012145525]

The cadence is so weird!

[@erikaacharya948]

I like how you tell the truth about skincare❤ Thanks a lot

[@stephanieshanonn366]

I use retinoil in a sandwich method. I apply a moisturizer then the retinol and lastly more moisturizer and let each layer dry/soak in first. In the morning I will rinse with luke warm water and apply a serum and sunscreen. This routine is working wonders for me.

[@valdez3245]

I do something similar, and yes, it works!

[@Sweetandsour90955]

Could i use Cerave moisturiser cream? Is it safe to use Tretinoin on the neck?

[@Kimi95B]

yeah it is hard to get just tret in Poland, but it is prescribed with antibiotic in a gel form - it is called Acnatac

[@Andrea-ue7gv]

You can just order it online from india, spain etc

[@21972012145525]

​@@Andrea-ue7gvid me scared of getting a fake. Though I would prefer from family visiting

[@smushface3999]

He said “banned for cosmetic purposes”, which I interpret as banned in OTC cosmetic products… to my understanding, this is true.

[@21972012145525]

Yes, but I think he said retinoic acid? If so that's the same as the us. You need Rx for tretinoin (retinoic acid)

[@SueRosalie]

well yes only because it is a prescription medicine subject to drug regulations so you can't just whack it into a cosmetic product

[@Clowanda]

Thank you! I just saw Dr. Greger speak yesterday and he went into this topic and said tretinoin may cause early death and it freaked me out.

[@TrinaDimple]

Whoever using tretinoin for longer time do your liver test, and lipid profile frequently, if some are suffering from irregular periods after using tretinoin, it because of tretinoin, many people are suffering from headaches and body aches etc

[@SueRosalie]

false. There is such a negligible amount of vit A it can't even reach your bloodstream, let alone your organs. Nor does it have anything to do with hormones. You need a better basic science education.

[@21972012145525]

Thanks for going over the study again i mustve missed the other video on it. Can you explain the 50% increase though,,? I feel like that wasn't explained

[@jenc9956]

Dr. Dray I truly appreciate you and thank you for addressing this. I remember inquiring about Ttetinoin and deaths. So thank you. Question: does topical adapalene and tretinoin cause resistance to antibiotics? I remember you mentioning something similar to this before but cant remember exactly. Blessings~

[@morgianasartre6709]

Nope, topical retinoids have nothing to do with antibiotics or their resistance. She has said though that using benzoyl peroxide with topical antibiotics can decrease the risk of resistance occuring, also she has talked about using antibacterial soaps for handwashing and those posing a risk for bacterial resistance.

[@jenc9956]

@morgianasartre6709 Thank you. I wish I never stopped using my Tretinoin for 2 months now if I start back I might have to go through the purge all over again and what I am using now (Paula's Choice) for a while now has been making my face better and I wanted to implement the Tretinoin again nightly but I am hesitant. I also have Differen gel and not sure which to give a try again. Blessings~

[@21972012145525]

​​​@@jenc9956you should try differin, as it's supposed to be gentler. But introduce slowly

[@karend.9218]

These vets would also have been exposed to burn pits and toxic substances.

[@21972012145525]

Not all.

[@betzib8021]

I hope you also react to his statement that one can make an effective vit c intervention by mixing ascorbic acid with water and spraying the solution on the skin.

[@SueRosalie]

not even the expensive vitamin c toners work, so his home made concoction even less so.