Understanding the nucleosome

In this video, I describe how electron microscopy data and micrococcal nuclease digestion analyses were used to produce the model of the nucleosome, the core structure of DNA packaging in mammalian cells

[@riddheshahire2690]

Great explanation

[@scorcher911]

Thanks for the review professor! You should put time stamps to make it easier to review specific topics from the video.

Thank you for your suggestion. I’ll try to do it in the future.

[@JustSimpleRockets]

Such an underrated video

[@alexlee3511]

Hi Dr, thanks for your great video. However, i have a question: if a nucleosome can impede MNase from the digestion, why can we still assign the footprinting experiment of testing DNA periodicity with nucleosome?

[@omartouray2612]

Informative indeed!