Uric Acid: A KEY Cause of Weight Gain, Diabetes, Heart Disease & Dementia | Dr. David Perlmutter

Levels Chief Medical Officer, Dr. Casey Means, chatted with our advisor, Dr. David Perlmutter on the discovery of how the elevation of uric acid in the body is a causative mechanism in the development of metabolic diseases, and one of the key links between obesity, diabetes, heart disease, neurologic diseases like dementia, ADHD, fatty liver disease, and more.
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They also covered:
- The several mechanisms of how uric acid causes cellular dysfunction and insulin resistance, including oxidative stress, inflammation, and even preventing insulin from getting out of the blood stream effectively.
- The evolutionary reasons why the metabolic dysfunction and weight gain caused by uric acid would have benefitted us historically in terms of low access to food and water, by letting us more easily pack on weight and raise blood pressure. And how we now live in an evolutionary-environmental mismatch where this survival mechanism is now hurting us in the face of caloric abundance.
- The different dietary and environmental factors that generate uric acid, including fructose, purine rich foods and umami foods, dehydration, alcohol, and more.
- The optimal levels for uric acid.
- How uric acid impairs our hunger signals, drives us to eat, and even promotes risk taking behavior. We talked about how to reverse high uric acid levels as a way to unlock optimal health.
00:00 - Intro
03:12 - More than just gout
05:06 - A causative role
07:44 - The number one cause of death
15:24 - Evolutionary environmental mismatch
16:58 - High fructose corn syrup
22:27 - The dangers of uric acid
23:38 - Uric acid and dementia
30:33 - Too much fructose
41:32 - Erectile dysfunction and cardiovascular risk
01:03:17 - No need to eat sugar
Transcript & Show notes: www.levelshealth.com/podcasts...

[@tonyprice2256]

I am 66 and use no pharmaceutical products - prescribed or over the counter for any reason whatsoever. I used to be morbidly obese according to two medical doctors. I used to have a fatty liver condition. I used to have pre-diabetic symptoms. I used to have edema - swelling in the feet and lower legs from excess fluids. That edema sometimes caused serious infections called cellulitis that would require hospital stays and intravenous antibiotics. I used to have COPD symptoms from decades of smoking. I used to have occasional high blood pressure and other chronic health problems for decades. All of these are gone. And they are gone because of intermittent fasting and eating high quality locally produced real foods. For just over two years, i have been eating just one good meal every day that i prepare myself. I avoid sugars, all highly processed junk 'foods' and excessive carbs - no breads, cereals, pastas, etc. I am healthier and stronger than i was 10 years ago. It is almost like aging in reverse! Barring any serious injuries, there is no need to see any medical doctors. I have no plans to see any in the foreseeable future.

[@nickc63]

Kudos to you for having the fortitude and discipline to get yourself right!

[@tonyprice2256]

@@nickc63 Thank you sir! My best wishes to you and those you love!

[@shwetasharma8093]

What does that one good meal a day you cook by yourself comprise?

[@monicakennedy5234]

Hi Tony. I developed edema in my legs 2 yrs ago due to lack of vitd3 and insomnia, which affected my immune system .. I had already self diagnosed with Bartonella related to Lyme, a few yrs previous, which I think I got from a blood transfusion a few yrs b4 it presented , im usng herbal treatments as I dont want to use antibiotics long term ... they are good as a first plan of attack , but not for the continued treatment...Im curious as to what do you think are the best foods for lowering the swelling in my legs

[@saraswatkin9226]

No enforced vaccines either.

[@shancan6328]

My grandmother walked everywhere she went, ate mostly out of her garden which took up the better part of her back yard and worked in that garden often. I remember her taking the peels and veggie scraps out with a shovel and burying it in the garden. She drank milk, ate butter, made homemade bread every week, baked cookies and cakes and would eat the fat off of the roast along with mashed potatoes and gravy. Breakfast was eggs and bacon when or oatmeal. She had "juice glasses" that would maybe hold a half a cup of juice that she would squeeze from oranges. She had sauce dishes that held homemade apple sauce and other fruit sauces. Meat and milk and dairy were from local sources. She died one month before turning 104.

[@gloriamaryhaywood2217]

OMyGosh! Sounds like such delicious and nutritious food!# YUM! I have started cooking meals from scratch these past couple years, and leaving processed packaged junk on the shelf! It's a World of difference in Taste and in Health!!😉

[@eileenmcchrystal8471]

Can I ask what you mean by cooked meats by scratch? Thanks X

[@renoreb953]

She was stress free & lived a healthy life .

[@mariemcrae4027]

Excuse me sir what about the other people who didn't have ape ancestors? I'm afraid you lost me at that point

[@kathleenohara6152]

@@eileenmcchrystal8471 cooked "meals" from scratch ... In case someone hasn't mentioned it earlier. 😁👍👍

[@feliciahioe4261]

My oldest son is in his early 20's and he has type 1 diabetes. But thank God for this piece of article kzbin.infoUgkxVYhghKWmrUgXARZ_ydZTvmmcrw5L0I5i At first he thought he had the flu and was lying down on the bed for three days until his sister took him to the hospital. They took his blood and it was 600. What I do not understand is how he could have gotten it, since no one in the family has it. But he is winning the battle now. This is good stuff

[@doddsalfa]

The best way for diabetes 1 is a plant based diet =40-60% less insulin

[@mwj5368]

@@doddsalfaCarnivore Diet from just my view would lead to near zero insulin. I was a vegetarian for 32 years with a lot of metabolic syndrome conditions. I've improved vastly but still not perfect and pre-diabetic, but CD really helped and maybe this boy needs that. His sister saved his life!

[@doddsalfa]

@@mwj5368 what I have learned is that the cause of diabetes is animal foods but the cause of insulin spikes are often carbohydrates but also some meat and whey protein.If you go plant based whole foods diabetes in literally impossible .The vegetarian diet is often full of fats and sugar ,going carnivore take most of foods in general out of the diet

[@mwj5368]

@@doddsalfaThanks very much for taking the time to reply with advice! While I was a vegetarian I bought the lower carb Ezekial bread that was very expensive but I love bread and it was rated low carb. I also decreased peanut butter with just enough so I could taste it. If I went for a Subway sandwich I'd get the thin wrap but it was rare I ate in a restaurant or fast food place so that doesn't really count. I did make the big mistake of having a lot of Atkins candy like the peanut butter cups that were almost no carbs but high in "protein" which was the whey protein that for me triggered gout. So I tapered that but even then I'd still get gout attacks so I stopped Atkins candy all together and the gout went away. I at the start of keto or Carnivore Diet got gout two times. I learned I'd get it once, but after that I didn't get any gout attacks, but I do take Allopurinol and maybe some day I can quit that too. My uric acid was 5.4 last time about 2 months ago. I was very dehydrated and exercise riding my bike to exhaustion creating a good workout but not drinking enough water and learned the hard way getting two gout attacks even though I'm on CD, so on CD I don't get them as long as I stay adequately hydrated. So the longest time spans ever of no gout on CD, but I'll look into your veggie diet. what kind of veggies don't lead to gout? What is your diet like? Thanks again!

[@doddsalfa]

@@mwj5368 I got gout before 20 because of white vines and dehydration.Drinking a lot of water is gout biggest enemy.Good luck

[@Stillwaiting4number6]

I’m a physician and have been saying this for years. Wish more would think independently, analytically and strategically and not just from a memorization perspective. Appreciate this video. More docs need to listen and learn the truth.

[@bernadettemartins7913]

Wish you was my Doc

[@MNskins11]

In the age of centralized healthcare, doctors have become nothing more than glorified nurses.

[@regionalarrow]

Its unsafe for young dos especially to deviate from their med groups orthodoxy@ they've been cowed and threatened!

[@ChunkySalsa75]

There was a British doctor in the early 70s that said sugar was bad and he was laughed out of his field - the medical profession owes dr yudkin a huge apology, and needs to be recognized for his brilliant work

[@ih82r8]

If only. Instead we're told to just shut up "trust the science" and take our shots/pills.

[@christinediguistini8629]

Maybe you could spearhead that on some level.

[@fainitesbarley2245]

He was more than just a doctor. He was an internationally recognised top researcher. He gave evidence to the US government in the hearings about heart disease and diet. He was savagely attacked as a charlatan by Ansel Keyes who was promoting the heart diet hypothesis which proposed saturated fat as the enemy. Ansel Keyes won hence the change in western diets from our traditional animal based foods to margarines, trans fats and seed oils. The demonisation of traditional fatty meats, eggs and butter continues. The results can be seen in the health, weight and fitness of the American population, closely followed by the UK, Australian and NZ populations. Other European countries with stronger food traditions have been more resistant to the 40-50 years of bad science and propaganda.

[@teresatanyag8237]

@@ih82r8 , True. Trust the science. The “science” is done through series of experiments by trial and error. And yet, it is not 100% sure as in vaccines(Covid vaccines still in experimental stage they say).

[@hazelwork9332]

Yep, I have a Doctor who has an extra degree in gut health n treats people with diet n is giving a hard time by the medical system. Other Doctor 's roll their eyes n say "Oh alternative" as though that's a quackery.

[@Cocora22]

My doctor recently told me that the tests I was asking for, during my annual physical, were not necessary because I don't have symptoms. I'm 70 and generally very healthy. I told him that I had been to the endocrinologist a couple of years back and he told me to watch my TSH levels. They came back very hi. I begged the doctor for some of the tests that Dr. Berry and his colleague recommend as part of a health screening and he said no. No Uric acid test recommended. So none done. I just can't wrap my head around how these doctors practice medicine. My experience has totally been that they don't want to find out what's wrong they just want to cram a pill down your throat and damn you if you challenge or question their approach!

[@KetoKassy]

The tests you requested don't have a prescription medicine associated with the test results that's why. They only care about test results that will allow them to prescription drug you for money 💰 🤑 You need a new doctor.

[@karlfillmore57]

I have been fired by more than one doctor.

[@russellsueosborne9106]

Drs can’t be told anything !!

[@Cocora22]

@@karlfillmore57 😃Me too!!!!!!!!

[@DesiRush1]

That sounds more like you are his patient. Take back your power and remember that a doctor is a professional that you hire to help you manage your health. If they won't work with you, then find someone that will. You only get one body and you must take responsibility for it.

[@buddyrojek9417]

After the Covid debacle and how the health authorities all around the world couldn’t even discuss how to boost immunity naturally, I understood why they don’t tackle diet issues and education. The entire health system is geared towards caring for sick people, through “medicines” to nursing the acutely sick

[@sursurrus]

The US spends twice the OECD (wealthy countries) average on healthcare and all its health metrics are below average and trending downwards. There's zero spent on preventative medicine, and the US and New Zealand are the only two OECD countries that allow pharmaceutical companies to advertise pills directly to consumers. None of this is a coincidence

[@vetolongwene679]

Its all about the money. Obamacare proved that. Socialism FAILS every time it is tried. #ReleaseKenyanMarxistTraitorsPubliclyFundedSecretCollegeWorkNow

[@gwensmith6]

​@@sursurrus. You are correct.

[@shetlandannegair]

In the past couple of years I was diagnosed with Alzheimer's and Vascular Dementia and I was in pure shock over it, but I now watch more closely what I eat!

[@sallykelly7115]

Do a metal test,and avoid Omega vitamin,is full of mercury,take every day a B12 order form Vimergy company that is garanty pure, and liquid, avoid all sugar, oils,gluten,soy, lacteos,eat lots of fresh fruit in the morning, special Will bleuberries, Anthony medical medium videos and books can help you,he wrote 8 books

[@RAY-bg2po]

Try organic virgin coconut oil. Brain love this short and medium fatty acid. Also try to reduce uric acid, cause it block nitric oxide ability to transport glucoses inside the brain cells.

[@lita4458]

Check your b12 levels. And do not expect a doctor to understand it all. If you have an absorption issue it is b12 shots for life. Google misconceptions about b12.

[@mbrights3158]

Hi, can you explain what you mean when you said: “If you have an absorption issue, it is B12 did life” Thanks

[@lita4458]

@@mbrights3158 I meant shots FOR life, typo. My apologies If you have a b12 deficiency due to diet a la being a vegan or vegetarian you can simply get your levels up. But if anyone has an absorption issue like Pernicious Anemia (missing the intrinsic factor for absorption) it is not on shots, levels now good - stop. It does not work that way, one needs shots for life.

[@CP-nf9my]

When we took sugar out of our diets 25 years ago because we saw it affected our children's behavior, we were viewed as mean, even abusive parents. Thank God for mean (and informed) parents.

[@cherylween4973]

Why thank God?

[@CP-nf9my]

@@cherylween4973 Because I want to.

[@cherylween4973]

@@CP-nf9my 😄

[@liammhodonohue]

Then it turned up in 0% fat "diet" food🤦‍♂️

[@LK-pc4sq]

You live in a ignorant and narcissistic country. Catherine you just extended the life of your kids. Now both of you need to leave usa and into the northern latitudes of Canada as #USABurns or #Cooks from Climate Change!

[@chasleask8533]

I cured my gout overnight by cutting out all sugar . The disinterest shown by my doctor is almost comedic . Beware , sugar , yeast , alcohol .

[@bowhunter8235]

th doctor I consulted defaulted to what I've already heard..

[@chasleask8533]

@@bowhunter8235 If they can't sell you a pill they don't want to know .

[@kellykelly9521]

Change doctors, simply!

[@MarkShinnick]

Agreed...never experienced profound gout but only during a intense 2 weeks of beer and simple carbohydrates.

[@katiejon17]

I just left my RN career after 15 years because of seeing this. The past two covid years, and the healthcare industry showing it’s bureaucratic hand. Millions of lives would have been saved with cheap, well studied medicine - never mind our economy. Most doctors and nurses (not all) are industry robots. Good for you for taking control here!

[@athomewithjenny]

I just had a visit to the ER last night and the NP told me to stop eating sugar salt dairy and gluten. This makes what she said make so much more sense. Thank you!

[@zerotoleranceforsataniceli4794]

Sorry what's left to eat ? Doesn't it depend on what's wrong with you and what you may or may not be sensitive to ? Our grandparents and great grandparents did not have gluten sensitivities and they ate some sugar and salt but generally were healthier. So possibly gluten etc are problems now because of how wheat etc is processed or even grown ie GM. They consumed less sugar because they cooked and ate unprocessed food ie no hidden sugars. They couldn't afford to over eat either. Our soil and seeds are not natural anymore and poor quality. This will be highly significant but is not discussed.

[@Cocora22]

@@zerotoleranceforsataniceli4794 Well the list is very long. But you can start with meat/poultry/fish. Nuts plus any fats that are NOT chemically made. So stick to avocado oil, Olive Oil, coconut oil, ghee, butter. There's also a long list of really low carb veggies that are excellent. AVOID ALL fruit juices because they are high in fructose = sugar. Don't consume any vegetable oils. That should get you started. There's hundreds more.

[@zerotoleranceforsataniceli4794]

@@Cocora22 Thanks, I understood that. However, there's something not right that we have to avoid naturally occurring carbs incl. fruit. So I'm not sure that food science has got it 100% right. When I look around graveyards I can see many long lives were lived eating a little ( or maybe a lot!) of every food type incl. sugar but little would have been refined and even the sugar would have been unrefined cane sugar ie more like molasses. So the soil would have been better, the flour less processed and refined, no GM seeds. But also I suspect there are toxins in our water, air & food that may not be known that are bringing about metabolic illness associated with food. Why? Because we can't eat what our grandparents and great grandparents ate even if we don't eat processed foods. So maybe there is an elephant in the room that we don't see !

[@Cocora22]

@@zerotoleranceforsataniceli4794 I totally agree. I grew up on a country where everything had to be fresh, when I was growing up, because there was no real alternative. All the elders in my family have lived well into their 90's and very healthy minus a few exceptions and some aches and pains. In Colombia food was and in many instances is still grown without a lot of chemical enhancements. I have spent the majority of my life now, in the USA, looking to avoid foods infused with all kinds of garbage and I'm sure you know what a challenge that can be. There is a lot of information confirming that the grains used before the industrial revolution were indeed whole and not refined, now you can't even find those kinds of flours and people who have tried have great difficulty finding the seed material to replicate that kind of wheat etc. I have been off of sugar for a year and a half and on a very low carb diet. I am by no means on the perfect diet but just this little bit has helped tremendously. I do eat real food without additives but it is a real chore in today's world to eat healthy. There are so many temptations, lack of time and maybe also laziness to cook. Easier to pick the easy way out. I do love my sweets so when I hear people say that once you give up sugar for a few weeks you don't crave it....... all I have to say to that is I don't believe it. It takes a lot of will power for me to avoid sugars.

[@zerotoleranceforsataniceli4794]

@@Cocora22 Thank you for that. Do you try stevia as a sweetener ? I'm also wondering about coconut sugar because it may not be refined so perhaps it's not the sugar itself but the actual cane that is grown and especially the chemicals used in the processing. As I said ( I'm in UK) & the gravestones speak ! They didn't warn us off sugar and carbs ! but many couldn't afford to eat excessively and there were no mass produced snacks - I avoid snacks when I'm out & about 'cos they contain nothing but chemicals. Anyway, good on you to manage a low carb diet and no sugar!. I can't quite do that ie my carbs are around 100 g a day & I use honey as an immune booster every day. So I aim for portion control and not snacking and doing a minimum 12 to 15 hr fast. This appears to stop weight gain and I feel well on it & don't need meds. I just think that God didn't put us here to then poison us with the food he created for us - that may not be scientific but to me it's rational!!

[@knackfarm]

Brilliant talk. It hits that sweet spot between science/medical and layman understanding. I'm so grateful to Google/KZbin for giving medical professionals, who bother to continually challenge their own knowledge to live up to their hypocratic oath - First Do No Harm.

[@marilynrice7532]

Thank you... so absolutely true!!! Admire and respect a physician, who have a true desire to be a blessing, not a curse!!! Please doctors never stop wanting to know more!!

[@KetoZdrowie]

Yeah, same doctors have been destroying our lives for decades, keeping us on drugs, probably knowing that is all down to our wrong diet! But wouldn’t say a thing about it. Now as they are old and stuffed up with wealth or simply retired they’re trying to whiten themselves and suddenly become a hero. Their ‘coming out’ means little to me the older they are! I respect YOUNG doctors who are able to resist the wealth the pharma offers for upselling their drugs and keeping the patient with chronic disease for long long time 😢

[@TaipanTex]

OMG! I'm a medical professional and just hearing all this just blew my mind! To say understanding how uric acid affects these multiple pathways in the body is starting to tie up a lot of loose ends regarding the pathogenesis of these diseases is an understatement. It's huge! You guys are like the "Jedi Knights" of the medical world! Thank you for your dedication to learning how these complex pathways work.

[@tahliajayde]

Best thing that people with your experience can do is to make sure other medical professionals learn this information. Western medical professionals are woefully behind in understanding the holistic functioning of bodies.

[@oolala53]

Time will tell if this is as impactful as presented.

[@ripme6616]

Professional=Monopoly on harm U brain dead animals..stay away from our baby's' covidiots!!!

[@ripme6616]

@@tahliajayde because they follow guidelines pathologically and have forfeited their inherent acumen .

[@IceBear369]

This is possibly one of the scariest comments I've ever read...

[@ziggy33399]

This was a superb video (for me). I’ve been obese for years. I was slender all my life & when I began to feel the shift , told my family physician I thought my metabolism had changed. She said the metabolism doesn’t chance. I’ve taken ALL the shame & blame as I blew up. Now I’m 73 yrs old, a former dancer shame makes me unwilling (and unable) to walk or even stand without pain. I swim to get things moving . But I absolutely crave carbs. I drink smoothies (organic fruit). I’ve been told I just let myself go. I’m a shame. I have to “face this “, etc. I can assure yo shame or being yelled at daily has not worked. I DID, however, buy a glucose monitor when I became interested in intermittent fasting. Recently I found the two medicines I WAS ON caused weight gain (1) and the inability to lose (2) weight. So again, what I assumed was my weak character flaws & failures while water fasting were perhaps exacerbated by simply not understanding. Namely, the role of sugars as presented here. Get that monitor and starting over. Wish me luck. Need both books (gave his grain brain book to a neighbor who was diagnosed with Alzheimer’s ). Thank you for your guest today. Thank God for recommending I watch it.

[@zfid]

Hi Ziggy at the beginning of the pandemic I started 2 regimes..firstly intermittent fasting and secondly the wim hof method. Intermittent fasting of 16:8 works but I then started a monthly 48 hour fast to supplement the daily fast. Tough at first but actually something I found I started to look forward to and extremely effective to loose weight. I'm in my sixties and my weight had been stable up until my mid fifties when I had started to balloon up. I wish you all the best and am sure that you will see some progress as long as you put some action into your wishes.

[@chloesweet6667]

Seems that you are the right path now. Good luck and perhaps pretty soon you can dust off those dancing shoes again!

[@ziggy33399]

@@zfid I’m doing that now. Thank you 🙏🏽 much.

[@ziggy33399]

@@Samantha99652 yes, it’s occurred to me the “normal” is NOT the optimum range (and why is that)? I mean, with what we know today, it seems we can do better. That said, until they start TEACHING Med schools to actually teach nutrition (more than 1 week before getting their MD) , teach some things about fasting, autophagy, chiropractic, massage therapy, acupuncture , natural herbs 🌿 and more than prescribed drugs for symptoms we have growing sicknesses. Granted, surgery seems a prevalent and productive in the U.S. but why are we in such demand for it? Why isn’t surgery an “after all else fails” solution. Love my body parts , right?

[@SandraA535]

Good luck!

[@454roadwarrior]

I had Gout so bad I was ready to get rid of my big toe, Dr said, Get 2 pints of Dried Bing Cherries, I ate both pints in 2 days, Gout went away and it's been 25 years since I have had a attack... Dried Bing Cherries.. I never would have thought of that. Best thing ever...

[@robertmearns4490]

Dr. Pearlmutter should be awarded the Metal of Freedom for all of his contributions to the microbiome and, thus, our good health.

[@lotfibouhedjeur]

Don't you mean "medal"?

[@digmatology]

I've been telling people sugar is the problem and not fat for 12 years and people called me stupid. It's nice to see science and doctors finally seeing and talking about it, it's sort of a vindication. Everyone needs to be taught this and to understand that children needed to be protected from sugar as it is highly addictive and unlike heroin its on every grocery store shelf. There is no such thing as an essential sugar......

[@organicdudranch]

Hi Michael , its a fight huh ! my wife told me to write down the lies and hidden truths on a list. i stopped at 250 . sugar /fat lie is a big health lie, forcing people away from fat and also pushing poison fats has caused untold deaths and suffering. finally your vindicated. google secret covenant.

[@MelissaThompson432]

And wheat....

[@digmatology]

@@MelissaThompson432 true, wheat is sugar with a Hoodie on

[@spgtenor]

Sugar has been the scapegoat for many decades and yet there is zero evidence that sugar has any detrimental effect on human health. Go ahead and continue to listen to charlatans selling nonsense, but don't be surprised when disease comes around.

[@Borat_Kazakh]

There needs to be studies, replicated, positively confirming Dr. Perlmutter's hypothesis. Frankly, after all the hype over grain consumption being the source of all ills, it is now hard to immediately accept his latest idea. I have heard nothing presented by him that clinically establishes the veracity of his sweeping claims.

[@EmilyW.isawakenotwoke]

This is an example of what SHOULD be taught to us in schools. None of us left school with any knowledge that was actually important to look after our bodies, our minds, our planet and each other.. if we learnt the important stuff, I'm pretty sure the world wouldn't be in such a mess 😔🕊️

[@jsi4064]

Good comment.

[@markrussell4682]

Of course the world would be a mess. The world being a mess is a function of there being more than one human on the planet.

[@rockon8174]

School teaches you to do your own research. The library at the school was full of books on nutrition. Expecting to be spoon fed info is just being lazy.

[@arlenmargolin4868]

@@rockon8174 but school is supposed to alert you to what you should be studying and if you think that some fourth grade child is going to start studying some advanced medical treatment modalities without being coerced into probing this information then maybe Dr Seuss should be your medical practitioner

[@pilsyppah]

The things that you mention should be taught to you at home by your parents.

[@johnyewdall398]

It is not often when I finish listening to a youtube discussion I immediately start from the beginning again. Thank you.

[@valeriegoetz2988]

Joy in learning and going forward! 9 months after upload, you are still teaching this to us! Thank you!!

[@michaelmonaghan9226]

I'm extremely aware of what I put in my body and have no Doctor at all at 57 and I do not need one, but this guy is one of those rare Doctors that have not been indoctrinated and looks and sounds to me educated.

[@bradleyhasse5220]

Half the doctors are clueless these days. Thank you for teaching what should already be known.

[@soppybat]

Yes, they are puppets with strings pulled by Government and Big Pharma.

[@Absolomthecarnivore]

Just half?

[@marcob.7801]

They just dont give a shit!

[@miguelcalderon5976]

@@marcob.7801 Pkwy

[@nanouekonzo5581]

I would say3/4 of them are clueless.

[@McMillanScottish]

Don’t forget the government‘s role in this. Corn subsidies are a big reason that fructose corn syrup is so cheap. Mexican soda pop is made with sugar because they don’t have the corn subsidies. That’s also way it tastes better.

[@JJ-fr2ki]

My addition. I’ve briefly met Perlmutter two or three times and met his family. My impression was one decency, genuine care for human health, and energetic intelligence.

[@williamholten2088]

I'm a physician and most of this is new to me. I can't thank you enough for putting together this research and connecting the dots within the metabolic syndrome. I checked my own labs and there has been no uric acid level checked by my provider in over a decade. Thank you again. Great work!

[@ripme6616]

1# DO NO HARM !!!

[@ziggy33399]

@Lying Eyes politely disagree. Why? The people who live longest in the world are not big meat eaters…or animal eaters. They are in the “blue zones” and their diet & lifestyles are mostly plant based.

[@ziggy33399]

@Lying Eyes just checking sources is all. You be safe too 👍🏻

[@ziggy33399]

@Lying Eyes and with all due respect, keto people (politely) are misinformed. They have shorter longevity, not longer. It’s ok, I know it’s offensive but I’ve based this on lots of actual studies & books. If you enjoy books, I am happy to supply lists to prove (actual studies , science ) for enlightenment. Most keto people are interested in their weight (like Atkins) and then get sucked in (as far as I can tell & from my own experience). Tell me what you’ve read proving those who eat meat live longer healthier lives. Thank you.

[@WholeCosmos]

I have gout. I have had it since 17 at my most fit time in my life playing on 3 soccer teams.Diagnosed finnally at 24. 7 years of hell and doctors like this who know just enough to be completly wrong and misdiagnose me. Gout caused by high uric acid serum levels is a genetically inherited disease of DNA metabolism due to the impaired metabolism of the purines in DNA. All primates have this metabolism somewhat compromised. Sugar has ZERO DNA. Fructose is not directly metabolized to uric acid as this quack aserts. Most food does have DNA in it except refined foods like refined sugar. He is conflating obesity and sugar metabolism with DNA metabolism. Some skinny people have gout. Obese patients with type 2 metabolic sydrome x likely have gout from excess food hence excess dna as well as comnpromised kidney function the inability to excreet enough uric acid given the amount ingested over time. Fat people eat more food and therby ingest more DNA and thats why uric acid is high. There is no conection to sugar metabolism of fructose which does not require insulin. The only connection is a renal one(kidney) and how having a constant high blood sugar and insulin level impairs the kidneys function to excrete uric acid. High uric acid is a symptom of another serious disease like cancer or over eating not a cause of weight gain diabetees or heart disease. symptom of problems NOT cause. Fructose does not become uric acid EVER in scientific reality.

[@lauriejerome9179]

So wonderful that these 2 physicians have maintained their professional curiosity.

[@kimberpalmer9982]

My

[@spiralsun1]

You got that right. In other words it’s not a “job” or “who I am” but a fundamental motivation for truth. It’s easy to say, but in the long run literally everything good comes from that. Thanks 🙏🏻 ❤️‍🔥

[@nobodynothing2594]

I wonder if taking high dose intravenous VitC & Myer’s with higher VitC will help bring down uric acid?

[@Shalinee2212]

Well said!

[@57colliegirl]

Lifelong learning is for everyone! Doctors should not rest on their laurels. Their patients are surpassing them in nutritional knowledge--- thanks to THESE lifelong learning physician leaders. Thank you Dr. Purlmutter and others who care to know more and HELP others.

[@carolyncouch4094]

I could listen to this doctor talk all day too! That was a great interview. I learned so much and now I will change my diet. Thank you so much.

[@modalities]

Anecdotally, I suffered from chronic gout (Uric Acid levels) as a function of how much fructose (HFCS) i was consuming and creating metabolic dysfunction, for nearly 8 years. I would have about 2 flares each month. I started a carnivore diet in January this year and had the Uric Acid levels measured each month (decreasing from 9.2 to 5.9) by June (this year). No HFCS, Sugar or substitutes or alcohol. In March (going back in time a bit) I stopped taking Allopurinol. I had also lost 42 lbs by May. Two weeks ago I wanted to test my response to HFCS and consumed 13 grams (intentionally). I had (and still recovering from) a gout flare within 10 days of consuming the 13g of HFCS. After 7 months I was shocked and thankful that I had Colchicine and Allopurinol. So it appears that I have more work to to on my metabolic health. Thank you for publishing this video and the contribution of Dr. Perlmutter.

[@Smiles2U4Ever]

This lady doctor does an excellent job summarizing what her guest says. She interviews very well in my opinion, asks great questions and summarizes the answers for her viewers. She doesn't interrupt her guest at inappropriate moments. The first interview I saw of hers was with Dr. Robert Lustig. Excellent.

[@saginaw60]

Her voice sounds like one of those cold war air raid sirens.

[@joanneerwin8237]

Going 2 read this again 3 times have had 3 kidney stones surgery. DOCTOR RECOMMENDED a daily Lemmon in a little water, no stones 4 three years. HAVE ALLAPURINOL, DONT TAKE IT GIVES ME A SORE TOE, KNOW WHAT THAT MEANS. Have had Para thyroid surgery. THRYOID OFF THE CHART OVER 100 PLUS Medicare does not recommend treatment its my age, 85 sounds old but am active age is really just a number. Can not thank u enough.

[@SeeWoelfin]

@@saginaw60 I agree. It is very unpleasant

[@anngray9171]

I' m glad you have commented on The Voice. The poor girl sounds like a duck, but she could get that fixed. Unfortunately though, it makes one dread the segment when she chips in.

[@dogfacesailor]

A decade bout with Uric Acid due to high calorie high carbohydrate diet, eat-out lifestyle. Passed over twenty Uric acid based kidney stones, one 7mm. Weighed 263 at 72". Type 2 diagnosis. A1C hit 8.0, got it to 5.7 with running 35 miles a week. 16 years later...A1C Changed my diet big time, increased pH and Hydrate hydrate hydrate. Started a serious lifechanging physical fitness program, dropped to 219 (fit, doing 50 pushups thru age 49 Active duty Army). Now 209 lbs and a 6.2 A1C . NUTRITION is key.

[@LevelsHealth]

💦 So important! Thanks for sharing 😊

[@tommyharris5817]

I see you didn't lose much weight after running 35 miles a week and knackering your joints in the process.

[@proudgrandma138]

my Ex was 22yo, 6ft & 165lbs, did not feel well & had Excellent diet (no sugar- he hates sweet stuff & unhealthy carbs- donuts, cookies etc) & fitness (slim) but had very high levels of uric acid and BP of 280/160! We couldnt believe it & neither could any of his Drs. Said he was near having a heart attack or stroke. A specialist found, by giving him a radioactive substance to drink, it turned out he was born w 1 kidney 1/2 the size of the other with 2 arteries going to it. His body (as a fetus) knew the kidney was small so it grew another artery to it & kept his adrenalin going to pump more blood. Blood pressure meds made him so he couldnt get off the couch, "the wind has been taken out of my sails."

[@ginobrito1761]

@@aprilmay1700 lol projecting much

[@ingridburling8731]

What is AC1? Can you explain? Thanks.

[@dashagudym3938]

I love this channel. As someone who studied biochemistry I really appreciate how much you guys go into detail. Excellent!

[@alfredvincent13825]

Dr. Casey is a tremendous interviewer. Have not heard anyone better.

[@markusbroyles1884]

The sweet fascination of Casey Means in her unapoligeticly girlish but professional and scholarly entheusiasm is infectious and makes the dry topic come alive with zest. I love the chemistry between these two. David Perlmutter is a classic national treasure. Thank you for this breakthrough exchange ~ SUPERB !! This should be taught in more simplistic terms at all levels of public school from early grades. EXCELLENT !!

[@canyoncreekster]

Love the vocal fryy

[@VoiceoverMomentum]

This is the kind of podcast I find valuable.

[@romanesiow350]

Ok

[@7x779]

What's the quick conclusion on what uric acid levels should be, how to test for them, and how to bring them into normal levels?

[@sarahjarrell1262]

@@7x779 that's a great question.. It would have been nice had they told us about that🤔🤔🤔 but I believe it's just a blood test ... Certain types of arthritis problems CAN be a symptom

[@SisterShirley]

@@7x779 I recall Dr Perlmutter said his uric acid level was about 4.5 and that anything under 5.5 is good.

[@ralphrice4408]

Really good info, just way too long . Fell asleep.

[@foodsofthegods]

My father is an Internist with borderline high uric acid levels. He eats a lot of sweet fruits like grapes and moderate amounts of animal protein. I am a radiologist and I rarely eat fruits or anything sweet! I have borderline/high uric acid levels too. We were both educated in the classic, simplistic medicine paradigm, so we thought this uric acid thing has to do with genetics. I forgot to mention I drink very little water and eat lots of salt! What we just heard makes biochemical sense and we will try it. Medicine is fascinating when you start connecting the dots. Thank you

[@mayamaker8841]

Cut back on salt and drink plenty of water. It flushes uric acid out of your system.

[@shooster5884]

I have no medical knowledge but following a crash and reading a book by a woman who was in a wheelchair young from arthritis and decided to stop all the meds and use researched old remedies on diet. The key ingredient was Cider vinegar and honey in warm water first thing every morning. Within a month of being off the meds and a diet she worked out she walked for the first time in ages. So to avoid getting arthritis in damaged joints etc I started taking the cider vinegar honey in warm water every morning. What happened was that my acidic stomach and bowel disappeared and never came back. Before that just a cup of coffee was enough to cause me a problem. An older neighbor who had a few arthritic joints decided to try it and told me that a surprising side effect was that cramps in his legs at night had stopped happening. He only ate fresh organic food and didn't drink or smoke so he had a healthy duet already. So I suggested to another elderly neighbor who suffered badly sometimes from gout to also try it, and wow, it also reduced his gout to almost zero. It came back if he stopped taking it. I don't know how it works or if relevant to this discussion, but I'm just sharing my experience with cider vinegar.

[@lynnegullion-realtor2880]

how much apple cider vinegar and how much water and how much honey? thanks

[@matchapetals]

It's because apple cider vinegar helps reduce glucose spikes and encourages your muscles to uptake glucose

[@shooster5884]

@@lynnegullion-realtor2880 Apologies..I didn't see you question til now. I was taking maybe a dessert spoon at most in a small glass of water.. the honey, apparently a relevant ingredient in the mix, I added about a teaspoon ful. It wasn't exact.. in the book the woman varied what she took. She suggested anyone going to drink alcohol to take the same glass before going out to drink.. You could start with just a teaspoon of cider vinegar and I don't think it matters how much water or honey. One thing to know she said if you have quite bad arthritis is that it can take 3 weeks to a month to see a difference and in those weeks you can have more pain in some joints because - as I visualized her words - the cider vinegar is breaking down some hard stuff jammed in the joints and that's the cause of the pain..but once that's gone the joints feel easier.

[@skiph3]

My whole line on my father's side had gout going back to my great grandfather. Gout was accepted as something that was matter of fact. My first attack caught me off guard at age 42. BTW I'm 75 now. Years went by doctors never treated me for high uric acid. I was finally put on Allopurinol 100 mg/day 12 years ago and still had a gout attack. I'm now on 300 mg/day of Allopurinol. I'm a controlled type 2 with cardiovascular disease. Looking back, my doctors never considered gout as an important disease. This discussion is so eye opening and needs super exposure to all the practicing primary care doctors.

[@anthonyman8008]

It's the behavior that causes gout, which is an effect, not a disease.

[@skiph3]

It is now found to be genetic.

[@owenthomas9863]

have you found diet change effective?

[@JoseFuentes-fn3dl]

I was put on allopurinol about 10 years ago. I was experiencing a weird sensation on my lower legs. I would feel a warm and cool sensation coming and going throughout the day. I had to stop taking it. But I've modified my diet with moderate exercise and my levels are low now.

[@sallyinarkansas6644]

I wish you luck and the best with your transformation!

[@breizel4930]

It’s easier to commit to behavioral and dietary adjustment when one sees the big picture. Brilliant presentation of the essential hazard

[@scoobtoober2975]

It's easier to change when the change makes a noticeable difference. I've made lots of changes and have seen a noticeable difference in 1 week. Don't ask me how. LOL. Follow what all of these smart ones telling the real results of research and real results.

[@paddystark145]

It's nice to understand how diet has so much effect on behavior. Metabolic dysfunction = cognitive dysfunction. Our diet is the leading cause of mental illness.

[@anthonyman8008]

Watching Dominion and I stopped buying sausage egg muffins immediately! I eating fiber and mega dosing with apple pectin and acai fiber.

[@paddystark145]

@@anthonyman8008 I eat so much raw broccoli now. Since I began this about 6 months ago. No more acid reflux. It brought my entire digestive system on track. From hole to hole.

[@anthonyman8008]

@@paddystark145 and is high in sulferiphane, especially sprouts. Have you seen Rohnda Patrick?

[@rachelgeorge6294]

My dad was in icu because of gout around his thumb. He was eating a cup of Mott’s apple sauce for 3 days. It has high level of fructose.. He almost died after 4 convulsions and 5th one at icu. He gets gout when he eats any food with dextrose, peas spinach broccoli. He has varicose vein issues too. Dr. David explains everything my dad experienced. Very informative and thank you so much

[@xallstatex2910]

These are the people and the conversations that have the power to truly make a difference in our lives...!! #LOVE THIS

[@torasisroel7754]

This is an example of what SHOULD be taught to us in schools. None of us left school with any knowledge that was actually important to look after our bodies, our minds, our planet and each other.. if we learnt the important stuff, I'm pretty sure the world wouldn't be in such a mess

[@CariMachet]

People are not taught on purpose > it’s by design > stupid people are easier to manipulate > the elites rule the world > king with many heads

[@Truth1561]

Amen to that!

[@BCSTS]

Even medical students do not know most of this.....we must therefore become life long learners....keep digging & learning....but not everything out there is true...& there are many blocks...internal (our own bias) & external (society, politics, money, power et al) to discovering, and having access to truth & the means to use it. Also even real, true science is continually evolving. Discerning the 'truth' in what you hear, read, learn in school but mainly in real life is so important. Keep living & learning.

[@RigidRecords69]

why copy and paste someone else's comment?

[@RigidRecords69]

ahh, the name and avatar speak volumes

[@Followmybliss777]

Bottom line: reduce fructose, increase exercise, take quercetin, stay hydrated, reduce carbs and sodium, do not drink alcohol or drink juice or processed foods, eat meat in moderation, as they will slow down your metabolism, increase inflammation and increase fat storage. How much fruit should we be eating? I’d also be curious about the role of dairy. That pretty much leaves vegetables lol 😂 this is honestly fascinating and so helpful. So sad that most Americans don’t get this education.

[@LevelsHealth]

It’s important to understand that no natural food-including fruit-is inherently bad. The overall composition of your meals matters more than any individual component when it comes to your health. The extent to which a particular fruit impacts your metabolic health depends primarily on: - How much sugar is in it - How much fiber is in it - And the glycemic index of the fruit www.levelshealth.com/blog/the-best-and-worst-fruits-for-blood-sugar

[@user-kv1nn7zn8s]

This podcast has filled in some of the many gaps that I have missed in other lectures regarding metabolic dysfunction. Thank you for staying with "the problem". Fascinating subject matter.

[@febbral]

Hi, I had uric acid kidney stones at age 40, saw the head of urology at Lahey Clinic, he said to limit dairy products, chocolate sweets, drink plenty of water daily ,avoid the cranberry juice ,it goes in as a base but changes to acid which is a good medium for uric acid stones. Prescribed the 100mg allopurinol daily, 12.5mg of hydrochlorothiazide daily, and also 1 650mg sodium bicarbonate tablet to help control the uric acid. Also use honey instead of sugar, with coffee and or honey and lemon juice with water, have only had 2 stone attacks in 39 years, I` am age 79.5 years old male.

[@drbendaroo9610]

It never ceases to amaze me how we continue to survive as a species with all of the chemicals we are exposed to on a daily basis

[@AyeWitness]

I know! Our body should be congratulated! It always compensates to protect the vital organs.

[@youtubedrifter5594]

The human body is a literal miracle. Your body is the most amazing machine in the universe that we know of.

[@Ash-radio]

I have never seen a better host and better interviewee ever than Dr.casey .Unlike the usual interviews , she actually listens to the answers and understands and modifies furthur questions based on that. Also her questions are so relevant, its always gives you that " ya exactly what i want to know " moments. Epic ! never seen on tv nor social media anything better than her . Love from India

[@sallyinarkansas6644]

Her hand motions drive me crazy, otherwise I agree! She’s good.

[@businesshubnamibia7244]

@@sallyinarkansas6644 I like her hand gestures and face expressions. 🥰

[@pamelastgeorge4304]

Agree,she help clarify the information and pathways

[@kayoxford7442]

Listening to for the second time. I'm an admin. of a diabetic group...never knew this! Explains so much! Sharing with my group! Thank you so much!

[@trioray9090]

Don't think you are boring Dr.P, I am not a pharmacist, but I read the whole Merck Manual myself.

[@shantishanti1949]

I am female age 62 and have each 10 yrs gone up a size - I am 2 sizes higher than I should be. It’s steady at that size but cannot lose it. I realise that after this video that dehydration is likely my enemy. I eat OMAD one meal a day - I am not hungry before I eat. I don’t add salt and avoid salty food. Not a fruit or sugar eater. I eat healthy foods but I don’t lose weight. My doctor in passing said we will keep an eye on your uric acid as you get older. So why not do something NOW ? I will get Quercetin ? and take 500 mg of Vit C and drink water lots more water ! Let’s see if that helps. Thank you - great video.

[@francisvlatko2834]

Hello Di 🙂 After listening to the podcast, I've come to the same conclusion. Although I've cured my gout and even dissolved joint crystals with keto, I still have elevated uric acid. As I'm already dosing Vit C, the only medication I'll be taking is more water. Dehydration could certainly lead to fat storage as we've learned.

[@cynthiacole6140]

Dehydration is real. This has been plaguing my 90 year old mom. She’s back in the hospital with electrolyte imbalances, very low sodium. She has always been very healthy and normal weight but has never drank enough water. She forgets to because she does not like water. She doesn’t drink enough fluids in general, never has. Only drinks black coffee. It has become a real issue for her!

[@pat4005]

@@cynthiacole6140 Your poor Mom. Consider squeezing some lemon juice from a fresh real lemon into the water. That is not sugary at all, and gives a refreshing taste to the water. If it's tap water and /or room temp, that could be distasteful also. She really needs water for so many reasons. I hope she will get enough.

[@cynthiacole6140]

@@pat4005 great idea. she’s in an expensive assisted living facility. They come and bring her meds, they should be able to also make sure she gets fluids I think. My sister is going to discuss with them. Thanks for your msg!

[@kabugamuhuthu534]

Thanks so much Dr David for this very useful information. I find it very valuable. Also thanks Casey for the way you have conducted this interview. No interruption and the message just flows. Blessings

[@Gigi-nv5ev]

I’ve always been a joyful life long learner. This lecture/video has been fascinating to listen to! Both of you!! ✨🌟✨

[@barbarachandler4430]

Wow! It makes so much sense! I work with folks in an assisted living with a memory care building, where I have worked for 12 years. I’m 68 and intermittently worry about myself. I love sugary things and carry a lot of weight, and I know it’s put in things to trap us to keep eating it. I have given up my favorite ice cream that HFC. I have a Dr appointment next week, can’t wait to asked for my uric acid!

[@oznetyoutube125]

Wow, very eye-opening. As a DIY'er ( Layperson ) this kind of information, this kind of education and understanding of the human-machine is so difficult to find/get. Doctor, you are an outstanding Scientist! Thank You for not only your work but also for finding ways to bring us this information!

[@devonharrison7124]

Thank God for You!!! I bought the book Grain Brain and Wheat Belly about 10 years ago. It helped me to stay out of the hospital for bowel obstruction surgeries with scar tissue complications. I didn't have a doctor or surgeon that could teach me about How to Eat. So far I have not needed another surgery. This channel dropped into my feed today and I am so grateful to you both. I subscribed and shared with family and friends. I will probably join. Thanks again, Devon Harrison

[@manuhernz2745]

Only about 30% through this video and I've learned a ton about this subject. I suffer from gout so you can understand my concern. Thank you so much for making this video.

[@grubbetuchus]

I have to watch/listen to this interview again. There's a lot of information here to take in and assimilate. Great interview.

[@lisaget2508]

This is such a fantastic podcast. The exchange between the host and guest was so educational and beneficial to your audience. Thank you, thank you!

[@pandeykuldip]

Absolutely mind blowing to learn about these unknown pathways of metabolism.THANK YOU Dr David .

[@arvissmith6059]

I really like the lady Dr's articulation in summarizing Dr Pulmutters points. Thank you for your perspective.

[@janean3773]

Gout was misdiagnosed for years, then were told purines were the enemy, but we discovered on our own that high fructose corn syrup & salt intake were real gout triggers. This video has taken it farther & we're going to look broader. Thank you!

[@jefjaeger]

I am not arguing against any of this, as I am always trying to learn. But I have a gout problem, and my triggers are asparagus, shellfish, and some meats. Alcohol, a trigger for many, is no problem for me. I am far from perfect on sugars and salt, but I don't think I consume large quantities either...

[@14lou]

I know a Gout sufferer who has no sweet tooth and consumes virtually no processed food products. He doesn't mind an occasional drink, but never to excess. I think there might be more to gout.

[@chrismoore2178]

I am a 55 yr old male prob 10-15kg overweight and was having gout attacks approx every 4-5 weeks until about a year go when I started taking a vitamin regime that was aimed at raising immunity to Covid. 250mg Quercetin, 1000mg Vit. C 15mg Zinc and 4000IU Vit. D. I ended up getting Covid and it was pretty unpleasant but the unexpected benefit was complete cessation of gout attacks.

[@sunbeamred8175]

@@14lou too much red meat?

[@14lou]

@@sunbeamred8175 That could be a factor. He doesn't eat a lot of meat, but when he does, he likes a big thick sirloin, cooked blue.

[@GizmoFromPizmo]

I can't get over how interesting this interview is... Listening to it a second time now.

[@LevelsHealth]

Amazing! So glad you enjoyed it 💪

[@davidvandeusen3424]

Wonderful interview. This has opened my eyes to the profound health effects of uric acid and nitric oxide.

[@clararodas6243]

Thank you, thank you.I’m learning so much about what my dear father suffered from for some years, he just passed away in January. It was sad, to see him in pain, just taking meds!! He avoid some foods. But I didn’t know much about all this…I will keep learning. Thanks I’m grateful and try to get your book Dr. Perlmutter.

[@bigmoose1961]

Fascinating podcast, well presented. Thank you for bringing this to public attention. What astounds me is how something so logical and dare I say obvious has gone under the radar thus far. I'm based in the UK but expect similar problems exist in the USA. Go back a few generations. People generally ate to the calendar, seasonally if you prefer. Root veg in autumn/winter, blueberries in July, Apples in late summer etc. Nowadays we can buy blueberries for example all year round. I see an environmental link here. Save the unnecessary food miles, eat locally sourced seasonal foods where possible. It is what nature intended.

[@merynbulley3672]

In one word~Brilliant!👌💯 Thank you so much for this podcast Casey and Dr Perlmutter!🙏🌟

[@andrewwazagow9120]

This is absolutely one of the most informative and most beneficial interview regarding health. Fantastic knowledge , experience , and ability to relay it over - there is no way how to express the gratitude of multitudes BIG THANKS !

[@danielmierop662]

I’m diabetic type 2, also pretty educated about my body. This presentation is the best down to earth conversation about the current human condition, how body systems interact, and more. Thank You to both of you and all the researchers over time. Data and observations can be life changing and behavior fixing to have the best possible bodies.❤

[@zantecarroll4448]

listen to dr neal barnard on diabetes

[@OCRay1]

I wish I could speak as articulate, eloquent and intelligent as this man. Very interesting information as well.

[@SAHBfan]

I used to be very overweight. A low fat, low calorie diet didn’t really suit me at all - I lost some weight, but it seemed to be as much muscle as fat and left me weak, tired and hungry. I tried ‘The Atkins diet’ which was fashionable at the time and it worked amazingly well. 15 years later my weight is still under control and I am very fit and healthy. I remember at the time Atkins getting almost universal condemnation from just about everyone,everywhere in the medical profession or media. The ‘fat bad, calories bad, carbs good, fruit good’ mantra was not to be challenged. Seems Atkins was definitely on the right path, even if he didn’t have the full story.

[@jonesy2892]

Yes, I was also on Atkins around 2001-2002 and people gave me such grief over it, telling me I was killing myself and I would be sorry. I've spent the last 20 years eating the standard Western diet, full of carbs and grains, and now I'm working to reverse Type 2 diabetes and hypertension! I should have stuck with Atkins.

[@davidmaisel8062]

Everything I have heard today makes sense to me. I've had gout attacks but before I did I was having metabolic disorders. Changing my diet, has kept my uric acid in check. Regular testing has been a huge tool in keeping my metabolism in check.

[@raghuarmani8341]

What diet changes?

[@davidmaisel8062]

@@raghuarmani8341 The top things I cut out of my diet were beer, wine, (anything fermented) for vegetables I avoid cauliflower, mushrooms and several other high purine vegetables. Shell fish are absolutely off. There are a few lists of purine content in foods on the net. The best I found was Japanese. Mind you, this is a good strategy post gout attacks. You can adjust your diet slowly back as your uric acid balances out. Consult your physician about medication. Consider getting uric acid test meter they are cheap (under $100) . This way you have a better idea of which diet works for you best and your physician has a better idea too. Hope thar helps.

[@SpearChuckUngawa]

I quit sugar for new year's along with HFCS, wheat, corn and rice products. I feel great, 45lbs. lighter. I reduced comorbidities and save money on food as I no longer feel the need to eat every few hours. This is important with the food shortage coming down the road. Please use that in your lectures. Harden ourselves by going sugarless, grass and oatless.

[@pattyconley4096]

What do you eat? I'm not meaning to sound sarcastic or snarky. I'm curious because my weight is creeping up but I have several different health issues limiting what I can eat. A major one is due to no fault of my own, I only have 9 teeth left and they're going bad now too so I can't eat fresh vegetables and crunchy fruits. Any ideas that may help me??

[@nobodynothing2594]

I’m curious to know too what you eat.

[@MrChumpus]

@@pattyconley4096 I'm no health expert, but for the last 2 months I've been doing lazy keto and mixing it up with intermittent fasting. Mainly cutting out carbs and sugar. I've lost almost 20lbs so far. I will eat 3 organic pasture raised eggs and 2 strips of bacon around noon. Lots of water and some matcha green tea during the day keeps me full until dinner. I'll have a salad and some protein like a chicken breast or a package of tuna. I didn't realize how many carbs I was eating until i started looking at nutrition facts. This diet is pretty easy on the teeth

[@SpearChuckUngawa]

@@pattyconley4096 I juice for nutrition, green leafy stuff with lots of chlorophyll high in potassium and sulforaphane, cruciferous vegetables. I'll have 2-3 Kiwi to help keep blood from clotting, little meat.

[@pattyconley4096]

@@MrChumpus thank you so much!!! I know I eat way too many carbs and it's partly because most are soft and easy on my teeth and because my sugar is unstable. I never know when it's going to drop or spike or whatever it's doing. Thank you for your help!!

[@saraabrooks100]

Thanks, finally an explanation! You're helping me more than you know! Sara

[@lisamendez7513]

Wow, Dr. Perlmutter I believe everything you are saying. I am diabetic and have changed my eating habits and I am on my way to reversing my body mess. I see and notice my health improving. Thank you so much for educating the public.

[@richardvandenberg6379]

Here in New Zealand they are completely banning tobacco, but the energy drinks and candy is still at the front of the counter. Obesity is even worse than the US.

[@katekuhn8393]

Dr. Perlmutter-- I bought your book "Drop Acid" and also a uric acid home test kit. I was unable to reduce my uric acid with diet alone, but after monitoring my uric acid and my blood pressure I was able to demonstrate a direct correlation between my uric acid level and my blood pressure. Now on Allopurinol, my blood pressure has come down from 149/82 to 128/72 or even on occasion, 109/68. (I should include I am type 1 diabetic for 56 years.) The proof is in the pudding as they say. You are 100% correct! Thank you!

[@hadaku]

This is awesome information. I was first put on allopurinol for gout which hardly touched the pain. But never heard this. Thanks for this awesome podcast.

[@Bass7a]

This podcast blew my mind multiple times! It was able to explain the in-depth how my high uric acid levels relate to all my chronic diseases. Can't express my gratitude enough... Love you guys for putting it up 🤍

[@rollthers3157]

How are you doing now that it's been a few months?

[@Bass7a]

@@rollthers3157 Got my uric acid levels back to normal by replacing my protein intake with cheese and eggs. The purines levels in them are close to 0. Cutted anything that got sugar in it, including fruits. Went heavy on coffee and excessive water intake and got my purine levels in the blood back to normal in 6 months.

[@Whatever-00769]

There is something about Tumeric and high doses of cherry & celery seed capsules that lower uric acid. Also, the purines from meat also contribute to uric acid high blood serum.

[@judycindi8382]

❤

[@sursurrus]

I read Dr. Perlmutter's book, _Drop Acid_ and it was the final piece of my personal health puzzle. I threw out my fish sauce, stopped eating anchovies and ketchup (my only remaining sources of purines and sugar) and like magic my joint pains went away. If you're having trouble with actually eating enough vegetables and fat to be full, I HIGHLY recommend you make your own mayonnaise with a healthy oil and slather it on vegetables.

[@arjaysmithjr9083]

Wife and I went on a binge (sweets, chips, etc) and I wound up with Gout. I took organic chemistry and biology in college, so I wasn't lost in the weeds, but this video should be spread far and wide (like our bellies). We're going back on our Atkins diet, but getting a broader picture of what is really going on, is a great help.

[@patrickday4206]

Just drink cherry juice concentrate better than any medicine to get it under control!

[@bengrynol3494]

Learned so much about Uric Acid from Dr. P and had no idea how much of an impact it has on metabolic health!

[@jonathanblack3]

EXCELLENT exposé on such amazing capabilities we have within ourselves, and how we can choose to be aware of how to maintain our health through nutrition. 🙏🏿.

[@waw4]

Fascinating. Thank you for the presentation and for providing a link to the transcript!

[@nemo227]

This is the kind of information that can be useful to everybody. But we have to seek it out by our own initiative. We're not taught this as part of our "education" or upbringing. This video is worth listening to more than twice.

[@KaldoniaKaldonia]

Brilliant podcast, thank you! I'm unable to afford a visit with a functional medicine doctor, so like most Americans, I have traditional insurance through my employer and see a PCP. I've questioned the past two PCP's I have seen....please test my insulin levels and cortisol levels....they tell me "insurance won't cover it and it's not necessary...you're fine." I'm 55 yo female and never had high blood pressure until 10 years ago....slightly heavier now, moderately high cholesterol, osteoarthritis in hands two years ago....I don't understand why traditional medicine isn't on the same path as functional doctors!!! You are all so spot on! I have been working with food to help reduce inflammation and help gut health. I have belly fat and I know my liver is mildly enlarged. Why won't doctors listen to us????

[@mindtek_aus]

Because darling doctors are owned by the pharmaceutical companies and it's all about the money. Pharmaceutical companies know that fruit, veg and water and no sugar fixes almost everything wrong with us. A clean diet will fix your problems without any help from a pill pusher. 🥰

[@mom755]

Not so much that doctors are “owned” by Big Pharm as much as healcare schools are highly funded by Pharmaceutical Companies which affect the curriculum, leaving no time for relational metabolic courses. It’s not just medical schools as much as all healthcare schools. In the 1970s, a Nutrition class was a required course. This no long the case and is not even an elective. Much scientific research has been done since then, but is still not included in the healthcare curriculum. A relatively new specialty of Metabolic MDs is now available but not covered by Medicare and most insurance companies which puts it out of range for most people. Cardiologists are becoming advocates of this but one must already have the destructive process evident. Sort of too late.

[@fairyorphan]

Why??? Surely you must know by now Western Medicine has NOTHING to do with health of the patient at all… It’s about M.O.N.E.Y…. The System was designed from the beginning to make money off your SYMPTOMS, it’s not interested at all in curing you of ANYTHING. If your doctor were to use common sense in their practice or apply new knowledge that might actually get somewhere with your health, they would LOSE THEIR LICENSE 👈🏼

[@rethap3612]

Does the 'moons' show on your fingers (excl thumbs)? If not, your thyroid is malfunctioning which impacts the liver & gall bladder. Apart from exercise and Chinese herbal meds to sort out my metabolism, I use Lugol's Iodine to kickstart my thyroid. I "paint" it on my legs (with the dropper) after a bath or shower and it absorbs through the skin: two patches about as large as the palm of my hand. Keep on with it daily until it doesn't absorb anymore within 24 hours. However, if you're allergic to Iodine, first get medical advice. When the thyroid & liver works, high cholestrol drops. Also check out Dr Berg's videos.

[@dianaherring8594]

@@rethap3612 what Chinese herbs are you using to straighten out your metabolism??! Mine is zero.

[@oswaldjames6295]

Simply Amazing!! Gotta Thank KZbin's algorithm for sending this to Me; And I'll probably watch it a few more times. Great Channel with Super up to date content.💕 Keep Up the Good Work, Doctor Casey.👍👍💕

[@oleanscott3671]

So much more research can be applied to this subject,the majority of our food substance are filled with some degree of sugar,I thank you for the very much needed information relating to diabetes.

[@suzanne5971]

One of the best interviews I’ve listened to in years! I plan to re-listen, and take notes. That is how valuable this information is. Well done.

[@gooberdooberwunderb]

Thank you both for all of your hard work

[@lynnwark5238]

Thank you for such a comprehensive interview from the good doctor. This information is what I have needed for many years. I developed an addiction to sugar in my thirties and now have been obese for twenty of my 76 years. Looking in the mirror has been a source of shame and frustration that I blamed on my lack of willpower and discipline. The medical community only reinforced that opinion with comments to "not eat so much". Now, after being diagnosed with pre-diabetes (my doctor suggested eating more beans) it seems logical that I need to reduce my sugar intake to almost zero and increase my protein intake as well (more beans). This video confirms that my decision is correct but also points out that reducing my sodium level is just as important.

[@Tylox1]

I think beans are quite toxic .. go carnivore .. fatty hamburger is the best..

[@forrestslater9361]

Well done. Their frank and open discussions regarding the nature of science is refreshing. Mistakes can not be avoided where science is concerned.

[@MelissaThompson432]

I'm learning a lot from these interviews.

[@paulmastre8202]

You broke this down simple enough for this retired Teamster to try to understand.Keep up sending out the message. Uric acid is deadly. Thank you, thank you

[@fergferguson7370]

I’ve been doing the low oxalate diet in combination with carnivore and keto….all similar. I developed gout in the last year and have osteoarthritis from many injuries and operations.My main reason for this program was to reduce or rid myself of pain…my blood test have always shown elevated levels of Uric acid . I am improving and really think this video is right over the target…thank you. The more information the better we can be…with less pain…

[@nitenitenurse713]

This has connected the dots to so many of my health issues. Thank you so much for this invaluable information!!! 💯🤯💯🤯💯

[@margaritatoronto5491]

What a blessing to find such a great Doctor! Awesome interview!♥️😍👍

[@markvanwyk4963]

The world needs more free-spirited clear-thinking folk like yourself. I have a feeling our numbers are growing

[@paulknowles9727]

I'm only about 12 minutes in, but this makes so much sense in regard to Ketogenic Diets and High Uric Acid Levels; Keto requires a lot of Intermittent Fasting. A great reveal. Thanks.

[@sherry2993]

I had severe gout when weight gain out of control. Encased in fat. Unable to exercise! Got rid of the 210 pound obtacle in my path. Yep. It was a mouth attached to a male human...one I knew when younger. Grrrrr.... After kicking that weight to the curb...I got my weight and gout down. Much healthier! Now that diabetes is gone, high BP gone plus no longer needing lipitor per bloodwork.....I can continue on the diabetes health plan. The food pyramid. The balanced diet. 40 lbs to lose. Able and healthy to exercise. Glad I kept my thinner self clothes. By my birthday I will no longer make food my focal point. By memory and re-learned ways of eating...on I go. In knowledge and healthier eating per 2022/2023.

[@jldonnell1]

Holy mother of pearl! I have been waiting on this and I'm so glad this came up in my feed. This is awesome!

[@PS_testing321...]

The thing I like about your lives is that you pay attention to the people interacting on the chat. I have seen so many from others here they just carry on with their agenda and ignore the commenters. Keep playing attention to your audience. People appreciate that