Synthesis of cinnamaldehyde (Aldol condensation)

[@woodroses]

Wow this is some good chemistry bro, very nice file

[@THYZOID]

Nice to see you are back making some videos ^^

[@stevensu6699]

You just saved me so much work for my chem assignment Thank you!!

[@doyale2]

great to see that you're back!

[@AndresRamirez04]

Very interesting! I'm planning to try this reaction and was wondering if paraldehyde could work as a synthetic equivalent to acetaldehyde? It seems like a safer option to handle than the monomer. Thanks!

[@alacrity7591]

Very nice! I synthesized p-Methoxy-Cinnamic Acid from Benzaldehyde via Knoevenagel reaction as part of my undergraduate organic chemistry lab course - I'm specialising in inorganic chemistry, but that synthesis was one of my favourites. This one seems more challenging, at least for getting a good yield, but still very interesting to see!

[@Roknalnwader1]

Thank you, brother, but I want you to have the necessary ingredients. I want the ingredients to make a kilo of Bakelite. How much phenol, formaldehyde and hydrochloric acid should I put?

[@chemist27]

10:08 do you reuse the same cooking oil for other distillations?

[@RaExpIn]

I've been using this for about 10 years now. :)

[@crabcrab2024]

Nice job! Glad U R with us. Keep on! P.S. Could you please provide a reference to the original synthesis? That would be very helpful.

[@RaExpIn]

Thanks! Unfortunately, the procedure is from a german book called "Organikum" by Heinz Becker. And there's no translation :/

[@crabcrab2024]

@@RaExpIn Ich brauche keine Übersetzung 😉. Dieses Buch ist mir bekannt. Tolles Ding. Danke dir und viel Erfolg und Spaß bei deinen Experimenten!

[@RaExpIn]

Achso :D Es müsste S.521 sein.

[@crabcrab2024]

@@RaExpIn Danke! 🙂

[@RaExpIn]

Gern geschehen! :)

[@rezaalijanianzadeh4202]

Is it possible use Salicylaldehyde instead of benzaldehyde?

[@RaExpIn]

Yes, it's a general procedure. As long as there are no other functional groups, the Aldehyde and CH-acidic compound can be substituted by anything and it's highly likely to work.

[@moongloomable]

Is a new apparatus swapped or cleaned before the final product? How do you avoid contamination from the previous distillation.

[@RaExpIn]

Usually, I clean everything with soap and water, then with acetone and at the end with air or just letting it sit over night, before I use it again for the next distillation.

[@dimaminiailo3723]

I recommend using sulfuric acid as the high temperature bath filler. It is horrible to clean the glassware from cooked oil

[@antejl7925]

Hot sulphuric acid is extremely dangerous ..I'd sooner clean dirty glassware than risk that.

[@dimaminiailo3723]

@@antejl7925 I've proposed an alternative to oil. I've never had problems with sulfuric acid bath, btw

[@woodroses]

Are you insane why would you choose to use conc H2SO4 as a filler instead of mineral oil? That is just irresponsible, dangerous and wasteful..

[@dimaminiailo3723]

@woodroses As I've mentioned, it's easier to wash it from the glassware than oils. Personal experience

[@Anar10n]

Have you considered using milder catalysts? Like primary amines?

[@RaExpIn]

It was a general procedure. So, I didn't think about it. Would be worth a try. According to Wiki the yield should be at around 60%.

[@chemist27]

Sir Can you please make a synthesis of di iodomethane? It is the heaviest organic solvent and it can float an piece of aluminum I think that's why I really like it

[@juzeralirangwala3539]

What u r planning to do with this crude cinnamaldehyde???

[@antejl7925]

Pattiserie flavours?

[@sankarshanharidasan6751]

The yield could be increased by adding acetaldehyde in parts to a solution of benzaldehyde and alkali.

[@PepekBezlepek]

that residue tho 🥴 could be cool to try to work it up, might be a mixture of benzoic and cinnamic acid 😊

[@RaExpIn]

I actually did a few tests on it. As for example reacting it with sodium hydroxide and acid afterwards to precipitate it out.

[@ugarit5]

Do aldol condensation of acetone pls

[@RaExpIn]

I made a video about dibezalacetone. Or do you mean to react acetone with itself?

[@aribinu8910]

Complex synthesis, since it's a challenge to separate benzaldehyde, acetaldehyde and cinnamaldehyde, and they are easily undergo oxidation, the yield was so so, 23%

[@djchemtalk2946]

Nice

[@ThatChemistOld]

If you're gonna use chemdraw, please use a common style like ACS1996

[@RaExpIn]

I'm using Chemsketch, because I don't have a license for ChemDraw anymore. I will have a look at it.

[@dattatrayadalvi3749]

ok

[@AndresRamirez04]

Very interesting! I'm planning to try this reaction and was wondering if paraldehyde could work as a synthetic equivalent to acetaldehyde? It seems like a safer option to handle than the monomer. Thanks!