Vyvanse (Lisdexamfetamine) for ADHD: What you NEED to Know!

In today's video, we discuss Vyvanse (Lisdexamphetamine) a popular stimulant medication used in the treatment of ADHD.
Intro 0:00
What is Vyvanse? 0:19
What is Vyvanse used for? 02:06
How long does Vyvanse take to work? 03:02
Is Vyvanse addicting? 03:54
Side effects of Vyvanse 04:46
Warnings and Precautions of Vyvanse 05:37
Drug interactions with Vyvanse 08:53
Final thoughts on Vyvanse 11:10
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🎥 This video was edited by:
Rahul Kanchi / rahulkanchi24
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References:
Cytochrome P-450 CYP2D6 Inhibitors | DrugBank Online. (n.d.). Go.drugbank.com. go.drugbank.com/categories/DB...
Schneider, E., Martin, E., Rotshtein, P., Qureshi, K. L., Chamberlain, S. R., Spetter, M. S., Dourish, C. T., & Higgs, S. (2022). The effects of lisdexamfetamine dimesylate on eating behaviour and homeostatic, reward and cognitive processes in women with binge-eating symptoms: an experimental medicine study. Translational psychiatry, 12(1), 9. doi.org/10.1038/s41398-021-01...
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl,S. (2021). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 7th Ed. Cambridge University Press.
Vyvanse FDA drug label (2021) www.accessdata.fda.gov/drugsa...
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own healthcare provider for proper diagnosis and treatment.

[@3monkeysandamoose]

The clicking bothers me; sounds like good info but the clicking can be more than annoying for neurodivergent brains.

[@Winterdogmusic]

This is the best video on vyvance I've seen untill now. Thank you do much. This helped so much to understand this medication.

[@JessieThorne886]

This was so interesting! Now it makes sense that I got much better control over my binge eating after I was put on Elvanse by my psychiatrist (as treatment for my ADHD). I had a very good effect on my ADHD from Elvanse, much better than Concerta.

[@andreabranch1100]

Great breakdown on vyvance

[@nerdbamarich2063]

Thank you as always. Happy Sunday.💙

[@LevelheadedMind]

Thank you for watching 🙂

[@anstriagreenwood3365]

Just started today on 10 mg. Was fine and focused for a few hours then got sleepy and drowsy and couldn't stay awake. Too tired to function properly. This isn't supposed to work this way or is it? I feel like I took a sleeping pill.

[@baby-fork]

Man, mine hits right away and last 2-3h then I crash :(

[@anthonyvasquez1259]

Do you know about Geodon and Fanapt? They're both medications for the treatment of Bi-Polar/Schizophrenia.

[@Hey_Khushi020]

Hey i am using parixtocin from almost a year want to stop it does I'll face lifelong withdrwal symptoms or for a particular span of time does it will affect my memory in any way.। Pleass reply

[@OfficialRogue]

Thanks for the videos! Please make one about the non-stimulant medications 🙏 as someone with Bipolar Disorder (who might also have ADHD, since the adhd-like symptoms seem to persist even in euthymia), I'm interested in learning more about them. I've heard about Qelbree, but like all other ADHD meds it's not available in my country (Ritalin is the only ADHD med approved here)... what treatments can help with ADHD symptoms that are primarily executive dysfunction related (like chronic procrastination, chronic lateness / time-blindness, lack of motivation, sleep procrastination etc.)? Thank you 💟

[@thehouseofhorsepowerautobo4506]

Great question! I'm curious to read the reply.

[@andreasaasen5950]

Check out wellbutrin. Let me know how it goes. Wellbutrin isn't directly a stimulant but an antidepressant ndri. Only one in it's class. Will save more dopamine in the synapse which will deal with Adhd symptoms as well as pulling you a bit up out of the depression apathy

[@LevelheadedMind]

Bupropion can be an option as well as atomixetine and quelbree as you mentioned. Trintellix can also be considered. Though they all still have a potential to induce mania, but not as high a risk as the stimulants. You can also try natural treatments such as Omega 3s, B12, Rhodiola, OPCs, etc.

[@andreasaasen5950]

Wellbutrin ❤ works for me with bipolar 2, and suspected add symptoms in euthymia. Omega 3, magnesium glycinate and creatin definitely helps my bipolar too. I also some periods take NAC. Look them all up and read about it. There's also a bipolar guide to supplements online 😊

[@jackchop1576]

It's one of the few my regular doctor will continue if I'm between psych providers. I prefer Dexedrine though because it kicks in a lot faster but my regular doctor refused to give me that med.

[@Hadrian363]

I have been on concerta for 3.months and it doesnt do alot for me, it calms me down emotionally but still unable to execute my day well or keep concentration on activities even ones i like. My prescriber is starting me on vyvanse this week 🤞🤞🤞

[@ic_0129]

how has the vyvanse been going? Im on my thrid week of 18mg Concerta. The first three days were filled with insane motivation, focus and the anxiety I lived with everyday was gone. Im onn my thrid week and the only thing I notice now is that it gives me energy so I don't get extremely tired in the afternoons anymore even on nights that I don't get a lot of sleep. My doctor also advised me to take 1 in the morning and 1 in the afternoon because I feel like it only lasts about 6 hours. Im kind of curious if Vyvanse will get me closer to the first three days of Concerta.

[@nhcrabtree]

YOU MADE THE VIDEO YAY :) Thanks!!!!!!

[@LevelheadedMind]

You're welcome!

[@sidka8435]

Hello,and Dexedrine SR?

[@dannysmith8665]

Great video!! I did have a question about vasoconstriction, which you touched on. Can vasoconstriction lead to increased muscle stiffness and pain when taking stimulants? My Vyvanse works great but is making my whole body sore and flaring up my orginal areas of chronic pain. Thanks!

[@LevelheadedMind]

That is interesting. I would suspect inflammation and rule autoimmune conditions and leaky gut. Support blood and lymph flow with stretching and massage. Support gut brain axis with anti inflammatory diet and good probiotic like MegaSpore. It is possible Vyvanse is activating your sympathetic nervous system and therefore increasing inflammatory markers like cortisol.

[@dannysmith8665]

@@LevelheadedMind Thank you so much for the info! Is it true that caffeine also increases cortisol the same way? Should I be avoiding caffeine entirely while taking Vyvanse? How do the two interact?

[@stevephillips7264]

Christmas time I was officially diagnosed with ADHD ! I have finally been given my tablets sfter a successful ecg scan blood pressure etc , however I feel like nothing has changed but bare in mind I'm an ex coke head ! Might it be my dosage as I'm starting on 20mg , is that low ?

[@wenzhuandrea]

Vyvanse worked great for my executive function, but the effects lasted too long for me I ended up with horrible insomnia and had to stop taking it

[@mindfulmagician7550]

Did you try lowering the dosage? What did you end up taking? A non-stimulant?

[@shebeekitty]

Does anyone have any experience on Vyvanse, where it made you gain weight or increase your appetite? I have problems being underweight, so I’m hoping that this doesn’t make me lose even more.

[@chrispasson1940]

i believe it helps people lose weight

[@shebeekitty]

@@chrispasson1940 I’ve heard that, but my doctor said it may help me regulate my eating better which would obvi in-turn help with weight gain. I’m on day 2 tho, and I was able to force myself to eat better than usual so that’s good. 👍

[@chrispasson1940]

@@shebeekitty that's interesting

[@fabiosallesctba]

I was taking the 70mg daily doses of it. Needed to reduce to 30mg and will switch to Atomoxetine next month due to side effects. I had strong stomach aches and needed hemorrhoidectomy surgery. Good job on explaining Vyvanse. Do you have a video like this about Atomoxetine? I'll search. Thanks 👍🏼

[@LevelheadedMind]

Thanks for sharing your experience. I plan to do a video on atomoxetine in the near future, so stay tuned.

[@EphesianRose]

oops let me delete my comment requesting a video about Strattera LoL. ditto to the above!

[@g-uy9me]

I would think a common side effect or side effect would also be euphoria.

[@LevelheadedMind]

Definitely can be if abused or used in higher doseages than needed.

[@rosemiller417]

My Heart would stop before that happens!😂

[@g-uy9me]

@@rosemiller417 why?

[@saintessa]

For me I only felt the euphoria the first couple days I was on it (30mg) but also I felt so tired. Dr thought fatigue was my mind finally settling down. But I've also heard we get euphoria the first time we take it.

[@saintessa]

​@@g-uy9meI can't speak for them but I assume cause for some people (and depending on the day) vyvanse can have unwanted side effects like anxiety and high heart rate, so in those times I feel like if I were to exercise I might get a heart attack (just the heart rate makes me feel like that but I doubt it.) So sometimes the thought of a higher dose equals anxiety. Sometimes I put half my capsule in water and throw out the rest because at times I wonder if 60mg is too high a dose for me.

[@philippawagner2832]

"Effectiveness may improve over time". Is there a source for this? I can't find any. What would even be the mechanism?

[@LevelheadedMind]

Stahl 's Prescriber's Guide pg 409. I note all my references in the description. He specifically states that it can take several weeks to attain maximum therapeutic benefit. This is also what I see in practice with my patients as well, give it at least 8 weeks before deciding it is not working for you.

[@philippawagner2832]

@@LevelheadedMind Thank you, found it. Doesn't really convince me though, as I can't find an actual study. I have found one that describes this effect with regards to binge eating though. Perhaps that's what the guide is ambiguously referencing.

[@Etaoinshrdlu69]

As someone who takes this you have to take breaks from it otherwise you will find yourself getting strange thoughts and increased paranoia. Don't take it on days you don't work... or take a lower dose.

[@saintessa]

@@Etaoinshrdlu69 I don't get that but anxiety sometimes (mainly depending if I'm already stressed or not) so I don't take it some days if I know I'm gonna feel like that

[@Springmaskh]

I just started treatment 20 mg i am terrified of getting hairloss from it…. is hairloss a common side effect?

[@saintessa]

I've never read or heard of that being a side effect anywhere.

[@ic_0129]

how are you feling after starting it?

[@mmarconi6346]

That sudden death dors not sit well with me. It reminds me of the latest jab they're pushing. Not so comforting!

[@touseefmukhtar-js9rm]

Mam plz reply I'm on luvox for ocd but didn't get relief in my gad doc is adding lexapro with luvox can two ssri can be taken together is there any dangerous side effects? Plz reply

[@touseefmukhtar-js9rm]

@@stmrp8622 I'm on now luvox and Effexor is if safe

[@LevelheadedMind]

You will need to be monitored for serotonin syndrome.

[@touseefmukhtar-js9rm]

@@LevelheadedMind how my luvox dose is 200 ang lexapro 20 how should I monitored any advice please🙏

[@jamesb2166]

What do you mean by Cadillac?

[@Winterdogmusic]

The best one

[@Telluride7324]

She says because it’s the “smoothest ride” and avoids the roller coaster ups and downs of other stimulants.

[@bethhansenfitness8089]

Can you take less than 30 to start off?

[@saintessa]

I know they come in 20s possibly 10s too, some people benefit from those doses so I'm sure you can.

[@annaelisa6903]

can i take vyvanse and ozempic together?

[@Digmeup]

Yes , my endocrinologist confirmed this .

[@enzoelise]

I have

[@andrewhall7176]

Hehe, not the Cadillac of stimulants any more. Now it's the car which works one month and the next is a dud.

[@charityconsultants_dcss]

Here in Australia we have very terrible supply issue for the Lisdexamphetime / VYVANSE! Is that the same for you? We can only get either 20 or 70MG I was on 30 or 40MG and now jumped up to 70 as that’s the only ones available. Any insights of these supply issues?

[@dWFnZWVr]

The global shortage is starting to resolve itself, although periodic shortages may continue throughout 2024. Best thing to do is ask your doctor to issue prescription scripts more frequently (weekly/bi-weekly) to account for any time medication is out of stock. Then you’ll reduce the chances of running out and always have a new supply ready to collect. If you’re on 40MG and only 20MG is available you can prescribe 2x 20MG capsules to make up the 40MG dose. Likewise, you can split a 70MG capsule into two to get approx. 35MG - although this is less advisable unless dissolving in water. It’s unusual to see a sudden jump to 70MG from 30MG or 40MG. Dose increases are typically made in increments of 10MG. 70MG is the highest dose and you can open yourself up to the risk of abuse if it’s too strong for what your body needs. Side effects such as euphoria become more apparent in higher doses and it can lead to dependence.

[@saintessa]

Yeah I heard that! A few months ago my pharmacist told me they were out of 50s but I was just put on 60s in time I guess... Maybe it's cause it's recently been put on psb or because it's the first line treatment for adults with adhd, with more people being diagnosed too.

[@chrispasson1940]

@@dWFnZWVr thank you for your sound advice

[@chrispasson1940]

there are still shortages in Melbourne

[@Digmeup]

I started vyvanse very slowly . 10mg , felt drowsy .only 3 days. Then I took 20mg for 3 days in a row. I was so tired , while driving I felt the need to pull over and wanted to sleep. So I don’t really know if it’s going to get better , it doesn’t work. Or I really don’t have adhd after all, which was disappointing as I had hope for this as an older diagnosed female

[@Telluride7324]

I experienced this with Vyvanse as well but not with Adderall, which for me works much better in that regard.

[@Buppy710]

Vyv f me up ..what’s an appetite

[@PossessiveZ]

Did your growth stunt?

[@Danibehar76]

dear dr Rosa. Don't you know what's going on in medical schools regarding the dominant control big pharma has on the this institutes in every way from the learning material you've learned aimed to make a Production line of mediators between them and the general poblic by producing "doctors" ? didn't you find it bizarre that all illnesses are idiopathic and the "only" solution is that chemical or the other ? because a lot of doctors picked that up during their school years from all the censorship and the unwilling to give them persuasive answers for just about anything. or that you know exactly what I'm talking about but you just decided to go with it and be a happy part of the crimes against humanity for greed industry ?

[@dcone53]

Brother, this is an informative video on Vyvanse. Why are you here being angry about big pharma? Go somewhere else and get mad about that. Christ

[@phonemail1367]

So what's the Cadillac of all ADD non-stimulants that wont make you feel like a zombie? thanks