This team are the best molecular biology animators of the world. Not only because the videos look great, but they pay a lot of emphasis in brownian motion, random collisions, molecular twitching and protein overcrowded cell compartments. Being the most accurate artist view of the molecular sized life process, duplicates the beauty. Congrats!
@satisfaction2009eBay12 жыл бұрын
These animations are easily the best media productions in the history of the universe. [tear drop]
@edwinismail94013 жыл бұрын
fact
@MercifulArchitect Жыл бұрын
if we ever meet aliens, this is what they need to see first!
@Eduardado8 жыл бұрын
the frightening sounds make the video more interesting for me :)
@eireannsg4 жыл бұрын
The X inactivation is FAKE NEWS.
@colejohnson49414 жыл бұрын
@@eireannsg wut
@eireannsg4 жыл бұрын
@@colejohnson4941 You can't even write proper English. No wonder you don't understand anything.
@colejohnson49414 жыл бұрын
@@eireannsg Wow, you just got a lot of information out of a one word reply. Anyhow, I'm just curious as to why X inactivation is "FAKE NEWS"
@Justin-wm6qh2 жыл бұрын
10 years later, still one of the best if not THE best video with regards to X-inactivation ever!
@ozzie_goat10 жыл бұрын
I love the sound effects. Splat!
@michasosnowski5918 Жыл бұрын
Drew Berry and Etsuko Uno are gods for making this kind of animations happen. The rest of the team also does great job. Thank you!
@dvorakmichalek31213 жыл бұрын
This is blowing my mind. I dont understand like 80% of what hes saying but in highschool these are the questions I wondered but couldnt properly ask. I wanted to see. I wanted to see what was happening. Id ask questions but the teacher would look at me like I was crazy. I love watching these videos. Life is ridiculously complicated
@hilaltuncer61499 жыл бұрын
the best animation about epigenetics...
@TheMarcopolo8311 жыл бұрын
The best video of epigenetic ever, no doubt!!
@fleks1612 жыл бұрын
I absolutely love it! A whole lecture of epigenetics in 10 minutes. Hats down!
@geisonizidio2 жыл бұрын
Fantastic video! But we have more than just epigenetics here 😃👏🏽👏🏽👏🏽
@michaelqiu9722 Жыл бұрын
Not really. You don’t know basic stuff in epigenetics like H3K27me3, Chip-seq, DNMT and TET enzymes etc.
@Gelatinocyte24 ай бұрын
@@michaelqiu9722 that doesn't sound like "basic stuff", you just listed names of specific proteins/DNA sequences/RNA molecules (whichever they are).
@michaelqiu97224 ай бұрын
@@Gelatinocyte2 It's basic for people who study epigenetics
@Gelatinocyte24 ай бұрын
@@michaelqiu9722 you mean it's basic for *doctors* who *specialize* in epigenetic diseases. This video DOES touch upon the very basic (general basics) of epigenetics - like DNA methylation, and nucleosome modification and remodeling.
@neccowaif9 Жыл бұрын
Those sound effects! I love how they convey how squishy it all is in there. Thanks for these videos!
@ThiagoBenazziMaia9 жыл бұрын
Amazing work. I can just imagine the time take to made all this thousand atoms dynamics to work for the video.
@eireannsg4 жыл бұрын
The computer did it.
@Xakana11 жыл бұрын
This was riveting. This was included in my Epigenetic Control of Gene Expression class. Absolutely fascinating to watch. Thank you!
@CzechNeight Жыл бұрын
I don't see anyone else use audio as a metaphor. The sound effects makes these videos so much more engaging and accessible. I love stuff at this level of science that is meant for a wide audience. AND ITS 11 YEARS OLD!
@kunalpatil46127 жыл бұрын
This was absolutely amazing, with crystal clear explanation, visual and sound effects. The best educational video I have watched so far. Thank you very much!
@IntraFinesse8 жыл бұрын
I enjoyed the lecture. Great animation, it helped me visualize what was going on.
@francisduenas40728 жыл бұрын
this is one of the best descriptions + visuals
@preslavaberkova89602 жыл бұрын
Thank you so much! The bast animations I've seen so far...
@nonyabizniz2 жыл бұрын
How can one not be simply fascinated and intrigued by this? Outstanding video.
@EDUARDO123489 жыл бұрын
Am pushing the like button over and over again
@thomasrademaker233 Жыл бұрын
this is the most breathtaking animation of DNA. the sounds are everything
@hectorsantos46623 жыл бұрын
I'm following the playlist "Biomedical Animation by wehi.tv" and I've got to say, this is one of the most amazing and beautiful things I've ever seen. Great work.
@rafesmommy2 ай бұрын
This was a very descriptive, easy-to-understand video. Thank you
@nikitagupta61648 жыл бұрын
This is one of the best channels on KZbin. Great information, great animation, and weird, but great sound effects as well!
@ringoze3 жыл бұрын
Really like the voice-over style too.
@iestynne6 ай бұрын
Absolutely unbelievable. It's like magic. So hard to grasp that this evolved via stochastic processes. I do wonder if human technology will ever catch up. It's just so so far ahead of us, and took such a monumental optimization process to create.
@guitarkatie7 жыл бұрын
i love the sound on this!
@gspb412 жыл бұрын
hands down one of the best biology videos
@goaheadmakemyday71264 жыл бұрын
That's really, REALLY cool. But my question is why does the X chromosome undergo inactivation? If the female's autosomal chromosomes don't have to undergo inactivation and both of all her autosomal chromosomes can be active at the same time, then why must one of these X chromosomes be turned off?
@PatrickStaight4 ай бұрын
Do the histones detach from the inactive X chromosomes during mitosis (and then reattach immediately after)?
@hansmack67922 жыл бұрын
Your videos are so good! Thanks for your scientific and artistic effort!
@roidroid12 жыл бұрын
the sounds always really brings me into this world.
@walterricardomencholavasquez6 ай бұрын
Very good explanation and a wonderful video, thank you, congratulations.
@patriciabong204 жыл бұрын
Thank you so much, WEHI!
@mejjar5 жыл бұрын
This video is fraggin' awesome. Thank you so much!
@darleneestrada81018 жыл бұрын
I love genetics and these types of videos..matter of fact I plan to present my PHD dissertation in this format.
@charlespendragon17426 жыл бұрын
Thank you very much! You've saved my final exam!
@tarka38tara344 жыл бұрын
how did scientists understand all these mechanisms which are so complex and invisible, thank you
@kimanipatrick10 жыл бұрын
This is a very good clip. Great in terms of animation and explanation.
@marlenfalkenberg2751 Жыл бұрын
I absolutely love it. Thank you very much for this video
@gustavbloom77682 жыл бұрын
Amazing. Is there any debate about the sound effects ? I would vote for leaving them out. Thanks.
@TechyBen11 жыл бұрын
Nucleosome sliding? Wow. That is amazing. The fidelity and accuracy of the system is brilliant.
@inkajoo10 жыл бұрын
considering that all this evolved over time by itself, seems the essence of brilliance itself, or perfection, isn't actually rooted in the idea of the miracle, or spontaneous creation, but rather the patient testing and selection of alternative possibilities, and openness to change.
@TechyBen10 жыл бұрын
Roger Levy Sorry, that assumes the conclusion. I'm open to possibilities. Though I prefer what is most probable. As you say, we are required to think about these things, we cannot learn about them by selecting our beliefs by "chance". :)
@WellThatsSilly8 жыл бұрын
What you're saying really, is that if you have a jar of clock parts, and shake it for long enough, you may end up with a perfectly functioning timepiece? With the ability to not only write down its own plans, but also replicate itself by reading those plans. While the jar is still being shook.
@TechyBen8 жыл бұрын
That is the truly difficult part of it all. Get any (mathematical, logical or physical laws) system, then arrange it such that it does exactly what simple life/cells/DNA with RNA does. It seems to leave us with two difficult conclusions. Either the space of all possible arrangements is too large to allow for a chance, or we have to accept it as a given. The two ways to look at the requirement for the unprobable to have happened, is either that all possibilities did happen, or that one was more preferred over the other. No matter how we look at it, life is unique, and not mundane.
@regulate.artificer_g23.mdctlsk2 жыл бұрын
@@WellThatsSilly that's not how evolution works.
@WEHImovies12 жыл бұрын
Thanks everyone! @mdoerkse We use Maya for animation and After Effects for compositing.
@videodjuegos69143 жыл бұрын
A los primeros 4 días después de la fecundación como se encuentran los cromosomas X provenientes del padre y de la madre ???? me podria explicar porfavor
@PresidentOfBlah3 жыл бұрын
the animation and sound effects so scary - i forgot to actually listen to the spoken word. I LOVED IT!
@josephnolan73646 жыл бұрын
Excellent video, loved the combination of audio/visual effects paired with the soothing, laconic narrator .
@Daniela-jk3bg3 жыл бұрын
Loved the animations!
@hasnakhan24365 жыл бұрын
So which comes first: histone tail modifications or de-condensation (allowing TFs and histone modifying proteins to bind)?
@ShyamBhakta9 жыл бұрын
Beautiful molecular animations!
@pdjinne658 ай бұрын
Life is so incredibly complex. I don't think our brains are supposed to be able to understand all this, but it's fascinating that they can by naming things and understanding patterns. Compared to it, our micro-processors, CPUs, GPUs and AIs are children toys.
@mmcindy3312 жыл бұрын
Thank you for the AWESOME video!! HELPS A LOT!!!!!!!
@nmkadhim11 жыл бұрын
Subscribed. Amazing stuff, but I would appreciate it if you go more into details. This is very general and I'm constantly looking for detailed descriptions.
@carolblair2247 жыл бұрын
Love the sound track!
@budekins54210 жыл бұрын
Outstanding animation.
@fullsolangeveloso4 жыл бұрын
A really well-done video, visual and informative
@LejdiJ10 жыл бұрын
Awesome video and graphics!! great explanation! Thank you
@cr3flo11 жыл бұрын
Awesome video! I think the eerie background sound and the bad ass graphics make it so engrossing.
@yuanitalangi806910 жыл бұрын
Thank you very much....great explaining..
@BrentLeVasseur6 ай бұрын
Great job on the 3D animation for this video.
@DanielLee-jr5fr6 жыл бұрын
Excellent graphics and narrative!
@patchouliknowledge81124 жыл бұрын
Can you explain me how does allele gene's interaction of 2 female's X chromosomes work? I mean, if, for example, haemophilla disease appears as an X-linked recessive inheritance and a dominant gene turned up to be in inactivated X chromosome, so how does recessive gene expression can be suppressed by an inactivated gene in allele chromosome?
@bradhilton22832 жыл бұрын
this like something straight out David croninberg
@yasamanmirzaee41662 жыл бұрын
it was really helpful thank you so much
@abmalshehry111 жыл бұрын
Great video. Great explanation. Thank you.
@theoreticalorigamiresearch186 Жыл бұрын
I know the colors and shapes can be abstracted away to understand what is "really going on"... can those sounds be abstracted away as well?
@citizenofNecropoliS12 жыл бұрын
absolutely love the narration and sound effects!thnx!:)
@priyankasasmal48797 жыл бұрын
Thankyou for the detailed information. I liked the animation also. Can you help me solve the doubt which arised .. What happens when their is an X-linked disease in females if one of the X chromosome is inactive? We say that males are more susceptible to the X-linked diseases since they have only one X chromosome and females have another X-chromosome to overcome the defects in one X -chromosome.. So how it happens if the other X- chromosome is inactive?
@Taropok4 жыл бұрын
2:55 what happens during meiosis, does the inactive X chromosome gets reactivated again? what happens during mitosis, does the inactive X chromosome gets inactivated again in the new cells?
@drouhin11 жыл бұрын
OMG. I'm female, and I'm a little freaked out right now. >:O Awesome animation, though, and a great pedagogic tool.
@michasosnowski59184 жыл бұрын
Eat healthy diet full of fruits and vegetables. Exercise regularly, meet your friends or make some and your body would know how to repair itself and stay healthy.
@gretela466810 жыл бұрын
This makes me love science even more
@chantellehollingsworthplow46958 жыл бұрын
Thank you so much. Very helpful (if creepy sound effects - maybe that helped the info imprint on my memory lol). At the point when the egg has both maternal and paternal X chromosomes - before methylation occurs to silence one of the Xs,: DOES Crossover occur at this point (just before the silencing)?
@santhoshnagraju78598 жыл бұрын
what happens to the inactive X chromosome during segregation ???? is it active or inactive ????
@jogobig13194 жыл бұрын
bonjour Si un père ( cadet dans sa famille) qui a la calvitie et que à ses gène dans notre corps est ce que le fils est disposé à l’avoir ? Si oui y a t’il un moyen d’éviter cela ?
@VicKyCusTard8 жыл бұрын
when the view changes when the nucleosome remodeller attaches its like frodo put the ring on
@unknownvector18 жыл бұрын
This is just awesome
@pascalgrunder10553 жыл бұрын
Very helpful, Thank you.
@AB-if8pd Жыл бұрын
Who created us with this detail and harmony? I'm still baffled by one cell work, can't get my head wrapped around it and yet 100 billions of cell working in harmony which makes one of us a scientist, another a thief, a lawyer, doctor, a homeless, a brocker and so on and so forth. I am going crazy by all this precise detailed engineering that generates all kinds of molecular machines and regenerate itself. WOW.
@thienngoquang66173 жыл бұрын
Thanks a lot, I really love the video. Can you guys make another video explain more specific how one X chromosome is inactivated
@holyhell505012 жыл бұрын
Epicgenetics. Absolutely fantastic video!
@reveluvlinus60398 жыл бұрын
at one point the sound effects sounded like traffic lol but this is a great video to visualize what's happening
@jto129212 жыл бұрын
AMAZING. seriously, this is so useful. the animation is superb!!
@parnordqvist38952 жыл бұрын
But if both X-chromosomes were active, what would happen then? Would genetical abnormity appear?
@paramino11 жыл бұрын
this is so helpful, it clears everything!
@dummyhead312 жыл бұрын
Love the sound effects !
@huttarl12 жыл бұрын
Very informative. What are the sounds based on?
@lakea.62183 жыл бұрын
Subscribed - In theory, can X-linked genetic polymorphisms potentially be “inactivated” through this mechanism?
@retihedley648111 жыл бұрын
Bravo! Oncore oncore fro Aotearoa. Thank you for your amazing knowledge
@giovannapg75323 жыл бұрын
I love this video so much
@vinniesharon4774 жыл бұрын
Amazing compilation!!
@AnimeUni-versed5 жыл бұрын
This is amaaaazing
@asifdawar93025 жыл бұрын
Awsome collection
@Jindy26 жыл бұрын
Just great! Many thanks.
@mdoerkse12 жыл бұрын
WEHI makes the best quality animations of this type by far! Definitely some nice artistic style and with attention to detail and accuracy. I would like to know what software is used to in the whole workflow to produce these animations?
@RockerProf10 ай бұрын
What's with the weird sound effects? Distracting.
@phu8787 жыл бұрын
Terrible background noise -- please please please get rid of it! (for those who like it: just search Soundcloud for "terrible sound" etc and play in background).
@pdjinne658 ай бұрын
What software do you use to make these? I remember there was a Maya plugin for molecular modelling, but I can't recall its name.
@WEHImovies8 ай бұрын
kzbin.info/www/bejne/p5Pcq3ifd9uVjtk
@pdjinne658 ай бұрын
@@WEHImovies Very interesting, thanks very much sir, especially the part about alphafold