What Dr David Sinclair’s space-tested ingredient does for skin aging! Aeonia serum explained

In this video we learn about a new anti-aging ingredient created from an organism that spent over a year of testing in outer space!
An extract of the organism named bacillus lysate is being used in the pioneering Aeonia Age Defying Serum made by Delavie Sciences, which was co-founded by Harvard professor and internationally renowned longevity scientist Dr David Sinclair.
Today co-founder of Delavie Sciences Dr Kyle Landry reveals how this fascinating ingredient was discovered and what the studies show about its potential to protect and rejuvenate our skin.
#skincare #antiagingskincare
AEONIA AGE DEFYING SERUM is available here bit.ly/3vCT6cL
On the website you'll also find the results of the various studies undertaken by Delavie Sciences
PRODUCTS I USE IN MY SKINCARE ROUTINE, INCLUDING AEONIA shopmy.us/collections/243245
On this link you'll find most of the products I use in my routine with discount codes where available.
SUPPLEMENTS I TAKE: shopmy.us/collections/408665
I use affiliate links on this channel which means if you choose to buy a product using one of my links I receive a small commission - thank you! : )
Subscribe to my channel here / thehonestchannel
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WATCH MORE LIKE THIS:
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TIMESTAMPS
00:00 Intro and background
02:25 Explaining extremophiles
05:03 Bacillus lysate discovery
07:56 How it is made?
09:53 Is it a sunscreen?
13:28 What’s in the serum and what does it do?
21:19 How to use it
24:30 The gentler formula
26:49 The price
28:16 Is it microbiome friendly?
This video is not sponsored.
I've also written two fictional novels which you can check out here : )
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Edited by David at www.redfacilities.com
Disclaimer: This video and all content on this channel is for informational purposes only and is not intended as medical advice and should not be treated as a substitute for medical advice.

[@gailfernandes53]

David Sinclair has duped so many for money and unfortunately I dont trust anything he puts his name to - thank you so much for your wonderful channel

[@RamblinLu]

can you explain more? this seems like a statement that needs extra information given the weight of what you're suggesting?

[@stuartist]

Or a victim of a smear campaign from big pharma

[@thegreaterconundrum]

Same here - I can't trust a product with his name behind it unfortunately. But love Claire. Interested to see her results.

[@thegreaterconundrum]

@@RamblinLu Oh you can very easily google it, it made headlines.

[@elvira3919]

So true!

[@mdmebovary275]

There are lots of products available which contain both bifida and lactobacillus lysate. Korean and Japanese products have included these ingredients for many years. You can buy a terrific k beauty serum with these ingredients for around USD50. The Manyo Factory Bifida complex contains bifida ferment lysate, lactobacillus ferment lysate and Lactococcus ferment lysate and its around USD24.

[@4tun8nanette]

Please mention the product names and where they can be purchased.

[@jaimerogers1587]

Isntree Bifida is fantastic and around $20.😊

[@4tun8nanette]

@@jaimerogers1587 Thank you so much!

[@drnaelafaiz]

A dermatologist myself always using new products on myself fisrt...used 2 bottles with no visible difference or benefit If someone else has tried it out kindly share your experience. 0:36

[@thehonestchannel]

Thanks for sharing your experience here.

[@h.v.4148]

Dr Sinclair does excellent research. But he does not have a good reputation when it comes to commercial enterprises. So extra caution is needed.

[@paritroiana1386]

I'm looking forward to hearing your testimony on this serum. I can add mine here too after using it for a month. Problem is the thousands of products are being reviewed by so many so it's impossible to figure out which would work. I know there's no miracle product out there because I've tried so many. I'm always on the Quest to better my skin and enjoy watching all the interviews you do. Thanks

[@thehonestchannel]

I’ll look forward to hearing your thoughts on the serum. You are totally right in saying there are no miracles in a bottle out there though some products certainly do more than others.

[@veronicaspencelocke2003]

He kept saying things like: "I'll be perfectly honest with you..." "I'm going to be honest with you..." etc. so my 'radar' went up and I don't know if he actually *was* being honest. (My husband was like that so I may be biased!😅)

[@KingKikikoi]

He is a scam

[@commenting4love]

Healthy skin is built from the inside out

[@fionalawsonnutrition]

Your channel is back!! I've been checking daily so delighted to see this! 🙌

[@thehonestchannel]

I appreciate your support and concern for me so much. I'm just so relieved to be back!

[@shasdelossa]

Thank you Clare. I really enjoy listening to your channel. Congratulations on pulling the trigger and going full-time in the youtube space.

[@thehonestchannel]

Thank you so much ❤️

[@smallnwise1]

Claire, It's thanks to you that I started following Dr. Brad Stanfield. As you might already now, he's pretty harsh on David Sinclair. I'll be keen to follow your results with this product.

[@gillcameron8105]

I follow Brad also, and have heard several commentaries about David Sinclair from others. I'll pass on this also. Any peer reviews on this?

[@thehonestchannel]

Yes, the longevity scene is quite the battlefield!

[@monicab204]

Very interesting! I'm looking forward to hearing your review.

[@peshahgalen2768]

Super exciting! Excellent & informative interview!❤

[@thehonestchannel]

🥰

[@wienernanny8670]

Can't wait for next week!

[@mulville0]

Than you Clare, I've been curious about this serum

[@Angela-ut5tx]

Thanks for being on the cutting edge and not the same old same old. Can't wait for you review

[@AFndjdj7373]

Cool concept My understanding of Bacillus being so hardy to environmental stress is that it’s at least partly due to biofilm formation and spore formation. So essentially the bugs making a coat of armour. If you make a lysate of the bacteria (basically, broken down soup), I wonder if you’ve then just destroyed the very property that made them so resistant?

[@thehonestchannel]

Hello! I'll ask Delavie Sciences to take a look at some of the questions to see if they can answer.

[@debgilbert3206]

Fascinating as always! Would you provide a link to the website that rates products according to being skin biom friendly?

[@kathleen9456]

You’re looking pretty awesome Clare, so it must be doing something 😊

[@thehonestchannel]

Thank you Kathleen!

[@DanielNenesso]

I'm on the edge with this one! I'm looking to splurge on a luxury serum, and I'm very intrigued by the hyperpigmentation claim. The fact that it's in your personal routine is making me lean into it as I love your honesty and diligence. This may be worth a solid trail.

[@thehonestchannel]

I’m sharing my thoughts on it next week and I’d be very interested to hear what you think if you decide to try it. I had a couple of weeks of irritation so it wasn’t all plain sailing but the superior hydration claim stands up in my view.

[@DanielNenesso]

@@thehonestchannel Brilliant. I'll wait for that video to see your complete thoughts on it to further inform my decision. WIll definitely share my experience if I move forward and try it.

[@Angie-bt6qt]

@@thehonestchannel Yes intriguing for sure, interested in seeing your results before giving it a try. Looking forward to your video review on it.

[@shasdelossa]

Same here - I spend a lot of money on controlling my hyperpigmentation with monthly Chemical peels, led light therapy, serums, and sunscreen. I know the science is developing quickly and I really want something that can truly protect my skin.

[@debgilbert3206]

I agree. Looking forward to Clare's experience with the product.

[@janm9309]

Very interesting!

[@judyhall8074]

Thanks for all you do I’m open to trying new and innovative skin care products like the ones featured on your channel. I have gotten great results with Calecim skin care products for myself and hair care for my husband. Your honest reviews are truly appreciated. I look forward to trying aeonia and possibly cycling it into my routine.

[@thehonestchannel]

That is so great to hear Judy. Thanks for letting me know about your Calecim results.

[@valentina-pg4bj]

I think your complexion looks amazing, so I ordered the Aeonia age defying serum & I can't wait to hear your review on it. Thank you, Clare!!!

[@thehonestchannel]

Thank you Valentina. Let me know you think of the serum once you’ve used up your bottle. ❤️

[@Adhara740]

Can you keep us updated ?

[@valentina-pg4bj]

@@thehonestchannel I will!

[@valentina-pg4bj]

YAY!!!!!! You're back!!!!! 🥰🥰🥰

[@thehonestchannel]

You’ve been an angel through this. Thank you ❤️❤️

[@valentina-pg4bj]

@@thehonestchannel I love your video ...... "I'm so EXcited, I just can't hide it!!!!!"

[@thehonestchannel]

@@valentina-pg4bj 🥰

[@SkinObsessedMary]

I'm super intrigued and can't wait to hear about your 8 week results. My finger is poised over the buy button!

[@thehonestchannel]

This is why you and I do what we do. Our finger is frequently poised over the buy button 😁

[@SkinObsessedMary]

@@thehonestchannel 🤣

[@MarsX69]

Thank you for this interview Clare. Looking forward to the review of the product with before and after pictures after using the product for several months. Maybe you can ask your mum and dad using it as well 😊

[@thehonestchannel]

Than you! I think my mum would love to try this but we'd need to wait for the gentle formula to become available for her. She has quite sensitive skin.

[@gloriamitchell4005]

This is what I have been waiting for. I’ve already bought the original one and I did not find it too strong, but I want it to have a little more info on it so going to the honest channel is one of the best things that could happen for melike some breakthrough there’s so much out there making people one shot monies they really don’t work that we had to be careful for snake and maybe we have finally found something with Dr. Sinclair who I follow just he is so wonderful and as you are Claire, so thanks❤

[@thehonestchannel]

Glad this landed at the right time got you! ❤️

[@Lulu-kt6gr]

Isn’t Bacillus Lysate already in use in many other skincare products?

[@susanb3989]

I don’t think so? If it is kindly name the other products. Thank you !

[@thehonestchannel]

My understanding is that Delavie Sciences have exclusive rights but they are making the ingredient available to other skincare brands. It's not widely available yet though.

[@4tun8nanette]

​'Exclusive rights' seems to Dr Sinclairs MO. I believe he is trying to patent NMN which could make it very difficult to get in US. Not sure I want to support/buy from a company Dr Sinclair benefits from.

[@thehonestchannel]

@@4tun8nanette He’s certainly ruffled a lot of feathers!

[@sunnyelizabeth2910]

Sounds interesting...cant wait to hear your opinion, experience and results🤔

[@markmcgrath4853]

very good video clare ! where can i buy this product from ? thank you

[@thehonestchannel]

Hi Mark. Glad you enjoyed it. If you click on where it says ‘show more’ under the video I’ve included a link to the website

[@lindsayk40]

glad they made a gentle formula bc there is no way I am putting the citrus oils one on my sensitive skin.

[@joyhope718]

I was wondering if you could do a video on beauty electric devices for highly sensitive people?

[@jl22545]

Very interesting. Was any clarity provided around using this with tretinoin at night?

[@thehonestchannel]

They’re pitching it as a one and done serum, however I still use a retinoid three times a week with it without issues (excluding a couple of weeks of irritation at the start).

[@serenajarvis3548]

Sounds like ‘One Skin”? I love the less is better approach

[@lakeside23]

Someone mentioned Ivan Galanin on the Aeducator website did not approve of bacillus lysate in skincare, but 30 minutes later, I can't find any mention of it. Is there a link to this?

[@gillcameron8105]

I'm following Ivan. He's exposing some interesting practices on skin care and now microcurrent. Thank goodness someone is doing the deep dives on this unrequlated industry.

[@lindsayk40]

Shouldn’t the gentle formula be cheaper if it lacks resveratrol, niacin, etc?

[@theresatomasello1843]

Hmmm. I’m sure some/many of your guests selling skincare preview your channel to get your skincare bent and respond accordingly. Just a thought … and it makes sense for them to do that.

[@BlubbsX]

Is it a good idea to apply it to the skin with a microneedle?

[@thehonestchannel]

I’ll ask if someone from Delavie Sciences can take a look at the comments to answer some questions. Microneedling wasn’t used in the studies so all I can say is it’s not necessary to get results.

[@liviusss]

This was very interesting, even though I don't trust professor Sinclair anymore... But I thought at first it was something like the Alien movies 😅

[@thehonestchannel]

We went all out on the space theme this week 😁

[@loisenglund8842]

I have been using the sensitive skin product for 10 days now. I’m using it twice a day at this point. So far I don’t visually see a difference, but because of the science behind it and because I take many supplements recommended by Dr. Sinclair, I’m going to continue using it for several months and give it a try.

[@thehonestchannel]

Thanks for letting us know!

[@loisenglund8842]

I have also just ordered Aramore skincare lotion which has Nad in it. I’ll let you know if it does anything like the Nad supplement does.

[@kathleen9456]

Is this something that could be used with LED? Do they have before and after photos?

[@thehonestchannel]

They haven't done studies combining this with LED as far as I'm aware but it's an interesting prospect. They have a few before and afters photos plus scan images on their website.

[@cynthiacaywood8428]

Would you not use this prior to red light therapy? Will it diminish the effectiveness since it’s considered a sunscreen booster?

[@thehonestchannel]

I did wonder the same thing. Without carrying out a study into how it combines with red light I think we'd only be guessing.

[@feeltheillinois]

so what is the price?

[@thehonestchannel]

It’s around £100/$125 per bottle

[@ashleylala4293]

Wait a minute...there’s life (bacteria) on Mars?

[@surrendertoflow78]

I think it was to make sure there wasn’t contamination on the rover from Earth. (Like we didn’t introduce bacteria onto Mars/the samples we collect.)

[@lynndecarlo6704]

I wonder if it would help with hormonal hyperpigmentation.

[@thehonestchannel]

The different causes of melasma and how to treat them would be a good subject in its own right. I’m afraid it hasn’t been explored specifically in the Delavie Sciences study so I can’t say for sure.

[@lynndecarlo6704]

@@thehonestchannel thanks so much. I have 2 spots on the side of my face from after having my second son. Just never went away. He's 21 now! I lighten them all year with great skincare, tretinoin, exfoliation and always sunscreen everyday. But come June in Rhode Island in the U.S , 5min outside and they get dark again!! Ugh. I wonder at this point if laser is the only thing that would remove them! I'm glad your channel is back!!!!

[@thehonestchannel]

@@lynndecarlo6704​​⁠ A doctor was telling me recently how effective BBL is for treating pigmentation. Might be worth investigating

[@lynndecarlo6704]

@@thehonestchannel thankyou. I've super interested. There's some great places where I live to get it done. Always board certified!

[@sarahturps1384]

Too bad there's no mention of HOW MUCH this booster enhances the spf! 🧐

[@thehonestchannel]

It’s a good question.

[@ashleylala4293]

7:22 We actually do have UV-C rays reaching the earth’s surface now because the ozone layer has been degraded by the ionospheric heaters (which really ought to be banned from operating, IMO).

[@user-dr7el5ld3q]

Why do they make these products so expensive. TRIALING these products is just too expensive. I don't know how many new things I am trying but they so far are not doing what they claim. How is this any different. Do they really have to make a small amount of serum for that much money? It makes me wonder.

[@thehonestchannel]

I do ask about the high price in the interview and I agree it's expensive. This level of R&D takes money but we will see bacillus lysate being used in a range of products going forward and I suspect the price will come down in time.

[@idahardy4052]

I appreciate you but not David Sinclair! I used to listen to him on various podcasts but then he started selling stuff. So I had to go to old videos and see his Botox journey. He needs to make sure to disclose those injections. He’s got some really off sounding philosophies - he fasts quite a lot, does not workout and has tiny little arms like those of an 8-year old. This is concerning to me because I’m an exercise physiologist and I work with older adults who are fighting frailty. I do appreciate you, though I want you to know that.

[@thehonestchannel]

He definitely splits opinion and I agree with you that exercise and muscle strength is hugely important. I’m not familiar with his exercise routine. So glad you enjoy the channel ❤️

[@inthemystery8297]

If you can say that this product has changed things for you on your face great, I won’t say never. I am quite upset with what Sinclair did with MNM that I won’t purposefully support him in anyway.

[@idahardy4052]

@@inthemystery8297I know your comment was made for Claire and not for me, but I agree with you about what he did with NMN.

[@lolitanolita9107]

I would hope they would not use Phenoxyethanol... It's a toxic preservative. There are safer preservatives such as radish root, but beauty lines tend to go for the cheaper ingredients, and then sell the products for big $. They all have removed paraben but the majority replaced it with Phenoxyethanol which is just as bad. I hate to complain, but we all need to do better. I try to stick with clean brands.

[@thehonestchannel]

Preservatives in skincare is a tricky one. It would be great if they weren’t necessary but they are in most cases. This particular one is deemed generally safe for topical use at low doses. A Healthline article on it for anyone interested www.healthline.com/health/phenoxyethanol#is-phenoxyethanol-safe

[@sarahturps1384]

Could not agree more! Phynoxyethanol has been banned in Japan because it's so toxic. Not to mention it's irritating to many peoples skin. If they do use phynoxyethanol, I will NOT buy it.

[@lolitanolita9107]

@TheHonestChannel Thank you for the link, I am aware of what they say, as I have done my research on it. Everything they deemed to be safe at low doses, you end up finding out later that it was not so safe after all. Why not use the ones that are completely safe, like radish root, for example... And there are others... Also, if all the beauty products you use everyday, sometimes twice a day( body and face washes, toners, serums, body and face lotions) contain it, would that still be considered to be low dose? I personally would rather avoid, but to each their own. Most of these beauty brands care more about making money, then they care about their costumers. Beauty industry, food industry, pharmaceutical industry are all mainly garbage... Sadly, this is the world we live in, where it's profit over quality.

[@estelaverde4909]

This preservative is safe. I've also done lots of research and I'm convinced it's OK. I used to be super concerned about "toxic" ingredients in cosmetics,now I'm not, because I've heard so many scientists and doctors talking about toxicity control in cosmetics that I do believe them more than " natural" cosmetics companies that spread fear to sell their own products.

[@lolitanolita9107]

@estelaverde4909 That's good for you. I trust functional Doctors, I do not trust conventional doctors(they get paid to prescribe drugs)

[@simmo8u]

If you want to hear a top scientist cutting edge research get Dr Nathan Bryan he is expert in nitric oxide

[@thehonestchannel]

Thanks for this. I discussed nitric oxide with Dr Brad Stanfield on this channel. It’s an interesting one but as with the NAD boosters, needs further evidence

[@simmo8u]

@thehonestchannel Dr Nathan Bryan is the guy that studied under the Drs that won the noble prize for the discovery of nitric oxide. He took the discovery and developed the products they are world first and yes he has skin products. I listen to a lot of Drs on health in the nitric oxide with products no one is on the same page as him . Do yourself and viewers a treat interview him!!

[@surrendertoflow78]

Ah shame it has HA as an ingredient, I won’t use it then because I consistently have issues with products with HA. Too bad general (uneducated/marketed to) opinion outweighed research showing it’s not a good idea to try to get HA into skin from the outside.

[@thehonestchannel]

I don’t go out of my way to use HA either. I must check if it’s in the gentler formula.

[@surrendertoflow78]

@@thehonestchannelLooks like it is 😝

[@ILOVE2FeelGOOD]

£103 for 30 days

[@thehonestchannel]

Using it twice daily amounts to a lot, yes, which was why I asked about the price.

[@marcgutierrez2905]

Sinclair?? Isn’t he getting sued?

[@thehonestchannel]

Not that I'm aware of.

[@janpowell7536]

This does not appeal to me at all I much prefer natural products I have a bad feeling about it.