Why is knowing your free light chain ratio important?

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[@Willow2024]

Simplistic, yet very specific and easily understood explanation. Packed with all the important details of inflammation, CKD and Myeloma. Thank you so much!!

[@GloGlo-7]

Loved this video! Thank you for the easy explanation of the differences. Has helped me to understand . Thank you ❤

[@nolimitsshan9713]

My body is literally attacking itself. I've been diagnosed with MCAS. Im in pain almost everyday. Constant nausea, fatigue, muscles weakness and tenderness, joint pains, neuropathic pains and chest pain. Doctors still dont have a clue whats wrong with me. Hopefully I get some kind of relief soon.

[@HTUMyeloma]

Hi! We're sorry to hear that, please send us an email to [e-mail] and our team will help you!

[@bigmanbesses]

9713, I feel the same with my body turning on it itself. I was recently diagnosed with MGUS but I told that it usually does not cause symptoms.

[@justincase1575]

I have multiple myeloma. I am in pain all the time. Have not yet gotten the chemo regimine down yet. Hope it’s soon. This is miserable!

[@leannshort2211]

My body started attacking itself also after I got C in April 2021. It’s now Feb 2024 and I’m still suffering! I also think I have MCAS. All the symptoms. Histamine intolerance has gotten a little better as I’m healing my gut. I know I have had a leaky gut even before getting C but it got way worse plus added symptoms. I just got back my Kappa/Lambda test. They are both high but ratio is within normal range. I already know I have a lot of inflammation going on in my body. No Dr has helped me either, so I know your plight! 😫🤯 It’s so infuriating. And all they want to do is put you on pills… 😒 After doing much research over the past 3 years, I finally figured out on my own what the root cause is to all this inflammation and debilitating symptoms. My oral health. I have had 3 root canals in my mouth for 15+ years. They are causing systemic inflammation and disease. I am now working with a Biological Dentist who is removing them. One down, two to go. Great documentary to watch is Root Cause. Please if you have any root canals or Amalgam fillings watch this film! They can lead to all sorts of disease and cancers.

[@Fitafter50mama]

Since I caught covid a few years ago my body is attacking itself I don’t get answers and my kidney function is now low I’m so tired of king COVID but mostly tired of doctors knowing nothing about long COVID or best diets ect

[@jonathanbaby90]

My Kappa is at 28.1, my Lambda is at 14.6.. the ratio is 1.98. I am confused when you mention over 100.. what does that mean about a ratio over 100?

[@1GoldenBreeze]

My recent few labs show the last scenario Kappa rising, lambda dropping, and K/L ratio rising but I don't know if it's enough to be more than still just MGUS yet. We have been watching it for 11 years.

[@emmanuelking9988]

Clear explanation, thank you 👍

[@HTUMyeloma]

Glad you liked it

[@tracyt5522]

Wheew thank you for such a clear clarification on these cell test and numbers...

[@leannshort2211]

I said whew too after watching this after getting my test results! 😌

[@leannshort2211]

Thank you for this! I was scared when I saw my Kappa and Lambda were elevated. Kappa is higher than the Lambda like you explained. But ratio is within range at 1.60… Thank you for this. Now I’m not scared! Just another confirmation of the inflammation going on in my body.

[@Littlerockjw]

How are you now?

[@leannshort2211]

@@Littlerockjw Still have inflammation. I think my adrenals are tanked and I’m in a low energy state. Started eating pro metabolically about 2 months ago and I am slowly starting to get better. A lot of mindfulness and vagal nerve exercises are helping to keep me calm and is helping to calm my systemic triggers. It’s a long road for sure, but I am hopeful that soon I’ll recover. It can take 6 months for Mast cells to calm down so hopefully between diet, lifestyle and mindfulness I’ll get there soon.

[@marandabest8947]

So why would the light chains to be normal and the ratio to be high?

[@Emily-yv1qu]

Mine is 0.00 0.03 kappa lambda ratio and I am in so much pain. I have now been diagnosed with smoldering multiple myeloma.

[@masteronionnorth2341]

I had some recent blood work done Via my allergist. Some of the results were abnormal... My free kappa was 17.11 Normal range is 3.30-19.40 My free kappa/lambda is 1.54 Normal range is 0.26-1.65 My free lambda is 17.62 Normal range is 5.71-26.30 Additionally: other abnormal results: My Abs CD3+ (blood) is 0.657 Normal range is 0.856-2.669 My Abs CD4+ CD4 (blood) is 0.413 Normal range is 0.491- 1.734 Abs lymphocytes is 0.980 Normal range is 1.000-3.200 My Abs lymphocytes flow (blood) is 1.052 Normal range is 1.500-2.900 My IgA is 4.38 Normal range is 0.66-4.33 I have a history of weird symptoms. I've also had sustained elevated IgA levels for years now. Doctors are unable explain this.

[@msocr3215]

Husband diagnosed 2023 with MM. kappa/lambda ratio was 54.10.

[@Littlerockjw]

How is he now?

[@TheRykpaalt]

Great presentation! Thank you so much!

[@johnsontimbal7617]

i had high kappa light chain free 25 what is that means?

[@Littlerockjw]

How are you now?

[@diegorivera6164]

Hello.. how the total light chains relate to the free light chains tests in detecting MM? And How far can this ratio be to say it is MM?

[@maxwilcox2224]

what genes are these kappa and lamda chains from?

[@Katxseven]

Excellent. Thank you!

[@umibrahimibrahim4966]

The best explanation.. I looked hard for it.❤

[@garlandowls1134]

Okay. I have a question! My mother's Kappa light chain and Lambda ligh chain are both extremely high. Does this mean multiple myleoma?

[@Brucewayne.monster]

How can I contact you ?

[@Brucewayne.monster]

Hello Garland Owls11 please contact me

[@rdutaxicabtaxicabservice215]

@@Brucewayne.monster Hi. Are you a doctor

[@wandacabral8231]

Hola! También tengo valores muy altos de kappa lambda... 65.5 y 5. 5..

[@sachinjain3739]

Bhai aap ke num mil skti he kya kya tatment chal rha he ma ka aap ke

[@joslynsantana8236]

beautiful and simple explanation thank you!

[@HTUMyeloma]

Glad it was helpful!

[@Jeagerjaques]

Risk to B cell lymphoma?

[@AussieCat111]

It depends on other factors as well as just the light chains. I have IgM MGUS and based on other information from biopsy, etc. my risk is to progress to lymphoma (if anything). But for other types like IgA, IgG MGUS the risk is more to progress to myeloma. Not a doctor, just a nervous patient who has done a ton of research.

[@robbisplaylist]

Thank you very much!

[@HTUMyeloma]

Thanks for watching!

[@Martty_4]

I'm a caregiver for a myeloma patient and his kappa is 569 he was told to do chemotherapy and the side effects of chemotherapy also cause infection. Our medical system is flawed

[@HTUMyeloma]

Unfortunately myeloma is a very tricky disease. That's why with HealthTree University we're trying to educate patients and caregivers so that they have as much information possible so that they can be more informed on treatment decisions when talking with their doctor.

[@Martty_4]

@@HTUMyeloma the doctors gaslight the patient and every treatment has horrible side effects equivalent to euthanasia

[@easystudy528]

IgA 597 mg/dl IgG 644 mg/gl IgM 35 mg/dl Total light chain kappa 151mg/dl Total light chain lambda 157 mg/dl Ration = 0.96 Can someone explain this, am i on remission or not?

[@sunshinelovenv]

i have monoclonol gamathies. They send me those test. I have never fully understand this. If the doctor says the bloods are ok, From 3 doctors say the same thing. So I just dont worry.

[@HTUMyeloma]

Hi Nyvia, if you need help understanding your labs, please reach out to our patient navigation team and they would be happy to explain it to you over the phone. They speak Spanish too. 1-800-709-0113.

[@tracyt5522]

Do not dial the 800# given scam

[@garrettwhite9071]

My kappa light chains are the highest my doctors ever seen at the mm center

[@monicarust2383]

THANK YOU for this information!

[@HTUMyeloma]

You are welcome! learn more on our website and get more access to resources through healthtree.org

[@kathleenkoval3424]

?kappa/lambda ratio 0.20 ? Free Lambda LT chains 75.13

[@sachinjain3739]

Bhai iska tatment kya he bhai laba Kappa ka bhai

[@johnlewiskodhek]

Thank you 🇰🇪🇰🇪👍🏾👏🏾

[@konosamero3654]

👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍

[@ashishXL]

Thank you so much !

[@HTUMyeloma]

Glad you found it helpful!