3 Reasons You Should Supplement With Creatine | Darren Candow | The Proof Podcast EP

[@marilyn48ful]

Love your excellent questions Simon, you are always concerned about your listeners comprehension of the discussion. You are born to do these interviews.

[@karenless2231]

I've been waiting for the interview with Dr. Candow since Simon mentioned he was coming on the show. I just started taking creatine to help with muscle loss and hopefully improve my skeletal structure. It was amazing to hear so much in-depth research and all the questions I had were answered. Thanks for another outstanding episode.

[@alancampbell9376]

Why don’t you do a study with a group of people who have lower kidney function and evaluate the effect on those who are dealing with CKD.

[@Joseph1NJ]

If creatine causes muscle to swell with water what does it do to the heart?

[@soilikasanen]

And when mechanism is explained through ao. increase of IGF-1 & mTOR, what about the effect on dysplastic cells?

[@jondel3304]

​@@soilikasanen, what does all that mean? That creatine may have damaging effects?

[@chrisliang6250]

I worry about this aspect, it seems like it would push growth, possibly cancerous? Is it worth given the conversation seems to say, working out is 97% of the benefits.

[@soilikasanen]

@@chrisliang6250 Agreed. I'm not aware is there any large long term follow up studies on humans - in small samples all side effects aren't obvious.

[@TrudyContos-gq1bw]

What a great question I would have never thought of that one .

[@deborahshields729]

Simon, my husband and I started taking creatine after watching your last video about it. We started at a low dose and kept it that way. We both had problems with constipation even though we were drinking a lot more water and it completely changed the nature of our stools to be very sticky and tarry with a very bad smell. We both quit taking it and it took about a month before my digestion felt like it was back to normal. I really wanted to take creatine because the research on it is so compelling but I sure don't want to try again!

[@pdblouin]

Wow this is wild. I’ve been on and off creatine since high school, across many diets (now wfpb) and never noticed anything like the above, thankfully.

[@Jayjayjimbo64]

Try creatine HCL, supposed to be easier to digest and requires less

[@brucehall3214]

Odd. Add more fat to your diet. Creatine is only coincidentally involved with this tar doody.

[@ronhumphreys3762]

Just to add..a decade or so ago much of the creatine available was found with a process that introduced contaminants. The industry says this is all fixed now and some fitness experts on you tube, but I only trust crea pure, a originally german sourced manufacturing process of creatine. But with crea pure I think they may have bought the patent. Used to be back in the day creatine would automatically bloat you with water. The reason was found the contaminants not the creatine itself. I think in this cheap is not best. For years you had to search out the german manufacturing process now crepure it is pretty easily found.

[@lordofthegym]

maybe the creatine you taking not real one many not real that is why

[@TheIgnacio777]

Fantastic interview!!! You ask THE best questions!!! I cannot comprehend how u only have 56k followers!

[@TheProofWithSimonHill]

Wow, thank you!

[@narelled159]

Was really looking forward to this one. Always listen on Spotify but no option there to comment. This just reinforced the advantages to supplementing and provided more great information. Thank you.

[@TheProofWithSimonHill]

Thanks for listening

[@gailhumiston3890]

Great information for those who are plant-based. I have to wonder the group difference on bone density for post-menopausal women who don't eat meat as compared to those who do. 🤔 The study may never be done, but you never know.

[@azdhan]

This was awesome! Big thanks to you and your host Simon!

[@TheProofWithSimonHill]

You’re welcome

[@azdhan]

@@TheProofWithSimonHill I forgot to mentiom, I have come across scattered Google references about Creatine possibly elevating blood pressure. I would love to know what your host knows or things about that If it is true, in people with optimal blood pressure, a slight increase may not be an issue, but in those with hypertension or on hypertension meds, I wonder if it could be an issue

[@vaughanmoody]

Great questions Simon! Thanks!

[@Christine-flygirl]

Great topic, as a post menopausal 59 yr old, I take hydrolized collagen peptide and EAAs. I typically consume them separately (when at home) mixed in water, I’ve just started adding Creatine. As it is difficult for me to find time at work to take my supplements both capsule and powder, can I mix my collagen EAAs and Creatine powder all together in one travel container and take at once? Thank you

[@TheProofWithSimonHill]

Hello Friends, I'm curious to know which part of the conversation you found the most insightful and engaging. Also, if you have any other questions related to this subject, please post them below this comment. I'll make sure to include them in our next discussion.

[@jondel3304]

Should men over 50 automatically be using creatine if they resistance-train?

[@susanstarker1378]

Safety of creatine supplementation for cancer survivors.

[@glenntimberlake2413]

@@jondel3304 In many cases people who are tired or fatigued should be using Creatine as one of their choice nutrients after Vitamin D, K2 with Menaquinone 7, with magnesium Glycinate, NAC and glycine and taurine. Dr. Osborne and Dr. Wong should be names among those teaching the words of wisdom you will want to know. Google each of these and see why I think that is probably the case.

[@md82892]

Very basic question: If this is so essential for human health and only exists in animal based diet (meat, fish, dairy, eggs) how come a vegan claim plant based diet is optimal for humans? Could being dependent on synthetic vitamins and minerals for the rest of your life be an optimal diet? Can someone make his/her health better by going against a 1 million years+ evolutionary diet and eat foods that didn’t exist 99.99999999% of their existence on earth and use synthetic supplements to compensate the lack of essential nutrients? Would be great if you can answer these questions in your next sessions, but please invite someone that disagrees with you such as Prof Benjamin Bikman, Dr. Paul Mason, Dr. Georgia Ede, Zoe Harcombe PhD etc. If you only interview with vegans/vegetarians you’re basically in your echo chamber.

[@weston.weston]

This discussion is soooo good.

[@TheProofWithSimonHill]

Glad to hear that

[@leandrocaara]

Another excellent show, congrats. Where can I find your interview with Hamilton Roschel? I'm from Brazil and would really like to watch it.

[@stefanalexanderwennberg]

Question about its effect on the immune system: Ever since I went fully vegan eight years ago I never ever got sick. Except every time in the last two years I started to take creatine, one week into it I get ill. I tried it six times and at every single try I got the flu. When I stop taking it and after some time of recovery I once again don’t get sick until the next try of starting creatine. I am convinced by it’s benefits but at the same time getting sick (something really unusual for me) doesn’t seem like a positive effect. Of course this is just my experience, it might be totally random, but then again: Every single time! Are there any studies about creatines effect on the immune system? Do other people experience something similar?

[@ronhumphreys3762]

My preumptive guess is it has a to do with any contaminants that may be in the creatine not the creatine itself. Some of the manufacturers may produce things not overtly hazardous but with contaminatnts that may do things.+ So I would buy a better quality one not the cheapest out there, perhaps with third party tesinng or some equal. I get sick (a cold)when ever I take a certain neutrooic herb, so if that were contaminated in creatine it will not hurt you the herb, but I would get sick. You never do know what things absent third party testing . or some equal, a very reputable manufacturer perhaps.

[@stefanalexanderwennberg]

@@ronhumphreys3762 thanks for your reply! Contaminants are probably a issue for a lot of supplements. In this specific case I actually did take a tested and pure creatine (Creapure, from a supplier that does third party testing multiple times with every charge) and I still experience those effects. Which is why I thought more about the creatine itself as the cause. But who knows…

[@ronhumphreys3762]

@@stefanalexanderwennberg Yes creapure should be good. Hard to say on that. Why do I develop a cold whenever I take baricopa a supplemental herb for cognitive effects,, who knows. But I do, not a allergy, a regular cold comes and goes then I get another one.

[@stefanalexanderwennberg]

@@ronhumphreys3762 Mysterious…

[@susanstarker1378]

Thank you, Simon, for another amazing interview!

[@limitisillusion7]

I've been taking creatine for probably 3 years now, with a few months of spattered in. I can't honestly say if it makes a difference in my muscle performance. It probably has, but only slightly. I do notice I gain/lose weight when cycling on/off. I'm sharper from a mental standpoint these last few years, but that could be due to other factors.

[@limitisillusion7]

@@barbarafairbanks4578 Ya, for sure.

[@JanZigbe]

Can creatine be taken with tea/coffee/hot water/hot milk ???

[@TheProofWithSimonHill]

Heat accelerates its conversion to creatinine so probably fine if consumed quickly

[@Maku0san]

Great conversation about creatin, really enjoyed it, was very informative!

[@doncasto8520]

Thanks for this. I remembered about this episode that I didn't listen to it at the time. It answered all my questions.

[@jp7357]

excellent Yt. im a runner .. my egfr (creatnine) was 70 my egfr measured by cystatin-c was 120. i always use cystatin to estimate filtration rate (as oer peter attia)

[@TheProofWithSimonHill]

Yep as an athlete creatinine may not be a great estimate of GFR

[@annahurtado3136]

Awesome interview-wow.

[@lorrainejambor3258]

Can we have more information on how it might affect cardiovascular outcomes and especially blood pressure.

[@terrizierke8528]

I'm interested in this do...is it a problem?

[@Ciskuss]

they said it's secure

[@jeanbaptist6255]

I have been taking it for 6 months or so. My bp is about 110/70 I am a runner and resistance trainer

[@L.A.6482]

As a 60 year old female with muscle wasting, I’m trying this especially since I can’t eat enough that I need.

[@kst157]

What about cancer patients - does Darren or yourself Simon have ideas, thoughts or evidence about what they should do? Many thanks. :)

[@kst157]

In other words, is it likely to increase growth or promote growth of cancer cells? Or does it help those with cancerous growths? In principle? Thoughts…? Thanks. :)

[@ronhumphreys3762]

@@kst157 I am not one of those two but.. Creatine is known to stimulate our bodies production of IGF-1 which at increased levels is thought to stimulate tumor growth in some tumors. one of which is prostate and another I think is breast.. Those considered hormonal influenced tumors Creatine is not a hormone, but may stimulate us to produce hormonal type element,s which IGF-1 is one. Likely is hard to say, but I would not risk it.

No we likely would have seen the effect in populations that have used creatine for decades, and I don't think there is any such evidence

[@ebarr9476]

Creatine has really helped my when riding my mountain bike.... seems to really help in those HIT short climbs a lot for me.

[@anne-marieroy1234]

The first time I tried creatine, I had very big problems with severe diarrhea (I had to stop). I just started again with the Con-crèt brand, a product that is supposed not to cause gastrointestinal effects; is that true? If so, why?

[@altron1009]

I took creatine for a month started developing head aches and vertigo, water build up in my inner ear. I was drinking a lot of water, 3 to 4 litres everyday. First I thought it can’t be from the creatine? I went to the doctor I was told my ears are infected, took antibiotics for 5 days, headache and vertigo didn’t go away. I stopped taking creatine for 2 days my headache disappeared and vertigo started to go away. It was possibly due to dehydration, even though I drank a lot of water! It’s a shame I was looking forward to taking creatine for a long time, it affects people in different ways I guess.

[@BlackSeedOil20]

If you have trouble with hydratation, try taurine.

[@mechellespillekom5891]

I’ve just listened to this on the podcast and it answered a lot of questions I had after listening to your interview with Dr Eric Rawson. But I still wonder about Heart health and blood pressure, and would creatinine help with ligaments and tendons (eg inflamed Achilles tendons and plantar fasciitis - after an 800km hike lol)??

[@ronhumphreys3762]

I am in my seventies do strength training and some aerobics and have taken it mostly on for about 30 years. I do take a break occasionally from it, a week or so at at time. that. But my resting HR is 55 and my normal bp average is 110/60. I get a flu I have to worry the low BP, really, makes me feel bothered if it gets in the 90/50 range. I would not take it with high BP however. CHF they have supposedly used it to benefit but check with a doc first on any of this.

[@carptackula7536]

You didn't talk about the heavy metals found in creatine from china - or discuss brands that are trustworthy (german based creatine). Given we're talking about health this would have been useful for the masses who are probably going to go out and just buy whatever is cheapest with no regard for the origins

[@robertthompson5501]

A few years ago Optimum Nutrition sold German branded Creapure. Now Creapure taken off label. I assume it is a China product. It is worth your search internet for German Creapure the benchmark on which earlier studies were done. Beware of Chinese products they poisoned their infants with melamine tainted formula and USA dogs with melamine tainted dogwood. Melamine tests as an amino acid hence spikes product as Protein but is in reality inexpensive and toxic. 🏋🏻😊

[@glenntimberlake2413]

I would definitely like to know more about that… Thank you for mentioning it.!!

[@md82892]

Or you can avoid this by just eating meat, fish, eggs and dairy. 😂

[@jenniferhutson8579]

@@md82892Not a helpful response whatsoever. Look for independent third party verification on the packaging to confirm content and purity.

[@daniellefaith47]

They do talk about this subject around the 1:06:00 mark if anyone is looking for it, but paraphrased is 1. Use creatine monohydrate, not other forms, 2. Make sure it's 3rd party tested, 3. If manufacturer Creapure is on the box it is often the one used for these studies so it's a good bet.

[@delraycollins1341]

I don't get headache with this but I am getting really bad cramps in my kegs at night and I have been taking creation monohydrate for about 6 days now and I really want to get some advice from someone that has been taking this for awhile and I am 42 years old and this is my first time to be working out since I was 23 and I am 5 ft 9 210 pounds and I am really pushing my self every day to work out 2 times a day and I have been lifting weights for about 8 weeks and I just started taking creation about 6 days ago

[@falsificationism]

The guest pointed out he eats collagen for breakfast. Why? Doesn't it break down into constituent amino acids in the stomach anyway? What's so special about collagen?

[@skippy6462]

Collagen a marketing product only according to Dr Greger.

[@robertthompson5501]

Try it. You'll like it.🏋🏻‍♂️🏊🦊

[@falsificationism]

@@robertthompson5501 Why would I like it?

[@robertthompson5501]

@falsificationism Improves nail, hair and skin, integumentary. Integumentary. Helps post workout recovery. Protects joints and ligaments. I am aware some say it is a waste. Others swear by it. Find out for yourself, simple no risk. . Might make a difference for you. Works for me. I need a haircut. 🏋🏻‍♂️🏊🦊

[@Joseph1NJ]

Does creatine accelerate MPB (hair loss)? Dr Darren Candow, "Not at all..."

[@markgoicoechea7826]

How does creatine effect blood pressure

[@anne-marieroy1234]

The first time I tried creatine, I had severe diarrhea. Why did I have this reaction ? Is it normal ? Is it possible that some company of creatine is better than the other ?

[@BlackSeedOil20]

A week ago, I had strong cravings and probably malnourished as I have digestion issues and do not absorb food well. Now, after taking creatine for 4 days and taurine for 2 days, my appetite is cut to half of it was. Does this doctor do consultations, or does he just does research?

[@jakobw135]

Can you consume creatine safely while caffeine is still in your blood - as opposed to being in your digestive system?

[@glenntimberlake2413]

Why not?

[@jakobw135]

@@glenntimberlake2413 Because sites like WebMD point out that's the OPPOSITE & OPPOSING effects of caffeine and Creatine would create problems.

[@shirleykilbride4555]

What about active females 60s not taking HRT does it help with bone density also? Does taking creatine cause inflamination? I've noticed more inflammation in my lower body on the last 5 weeks when I started taking. Creatine 5 weeks ago ?

[@Mo-yj3wf]

Are you talking about methylation in this video?

[@debf9163]

My creatine advises it has to be taken on an empty stomach. I am really struggling with this. In this podcast, it seems to be fine to take with food. Which is right?

[@ronhumphreys3762]

Early thinking on creatine stated any glucose solution(carbs) would interfere with assimilation. I think this is now not considered fact. It may very marginally impact assimilation not enough to make a difference. Coffee was said as well. But seems the same only marginally. But purely for 100000 percent effect, if such a thing could happen..they are right.

[@riccimoragne3397]

What about the prostate! 36:59

[@wwilliams1358]

I'd like to know how/if Creatine affects the lungs?

[@Joseph1NJ]

What about creatine and BPH?

[@ross5960]

I took creatine for about 3 weeks 3 grams daily I like the results on my muscles buy after the 3 weeks my mouth felt really dry even though I was drinking a lot of water so I had to stop taking it does anyone knows how to avoid the dry mouth feeling. Any info will be appreciated. Thanks Ross from Chicago

[@Valerielaquidara]

I would try switching your mouth wash to biotene.

[@ross5960]

@Valerielaquidara are you for real or are you just kidding

[@jakobw135]

As for liver issues with taking creatine, if you've been diagnosed with mild non-alcoholic fatty liver - is that an issue?

[@ronhumphreys3762]

I have never heard of that as a problem. But if suffering any disorder you are well advised to consult with your doc before starting any new supplement.

[@BrovaKain_357]

Is creatine a single amino acid or when synthetically made is it a combination of amino acids?

[@Valerielaquidara]

It is a combination of 3 nonessential and essential amino acids which are national metabolized and stay intact.

[@swites]

Body make it from 3 amino acids

[@waynegoucher4503]

Could Creatine have any affect on people with Inflammatory Arthritic conditions?

[@nickflynn621]

The TL;DR here for me was if you’re a healthy individual and exercising you should probably be taking 10g a day split into two doses

[@jondel3304]

If my asthetic goal (for a temporary time frame) is maximum muscle striation and definition, should I stop using creatine?

[@ronhumphreys3762]

Are you using a high grade creatine?, I sound like a advertisement here, but cheap creatine by manufacturing process was known to contain contaminants that are not hazardous but may enhance water retention. Exotic combination highly priced is not necessar,y but good quality pure creatine is. Trial and error though, if preparing for a contest. Everyone is different in that, tendency for water retention with creatine.

[@susanstarker1378]

Is creatine supplementation safe for cancer survivors?

[@ronhumphreys3762]

Hmm seems to have disappeared the original response.. Creatine is known to produce IGF-1 stimulation production effects. So I personally would not chance it.

[@crocmandarin]

I get 10 grams of creatine a day in my carnivore diet. Also taurine, anserine, and carnosine.

[@Joseph1NJ]

Maybe I'll have to watch this again, but I didn't hear any real compelling reason to take this magic powder. All I heard it "may" make a 2% difference in performance. That's not a number, that's a guess. Hell a cup of coffee, or a spoonful of cocoa powder, or even a glass beetroot juice can do more than that, and that's been scientifically proven. Sounds like a waste of money.

[@ronhumphreys3762]

Some people are not receptive to creatine and some are. In study vegetarians and particularly vegans are. It should not play out that way in theory as our bodies make it but it does in observational study. For many it works. I find a much greater than 2% boost when I first took it years ago. Since then I have been mostly on it and it takes a bit to drain out of the system after taking it. So not so noticeable now. But it is way cheap as supplements go. If exercising particularly resistance training I suggest trying it then not buying it again if you are a non responder, Heavy meat eaters tend to be the non responders.

[@ashjan3317]

truth is you will use all the protein up even if it is 200gms in one dose

[@GNICHO]

The bass is the man’s voice just broke my AirPods 😭

[@TheProofWithSimonHill]

Haha sorry

[@meshari-yy9gp]

Too many ads!

[@manojreddy123]

Why don’t they have many studies on hair loss with Creatine? It’s a billions of dollars of industry and hair loss is one of the most important issues for men and they don’t even have a single study except for that rugby players DHT went up study? It’s weird and I wanna take creatine but also don’t wanna be the Guinea pig as I like my hair.

[@jakobw135]

P.S. to the question below: assuming my creatine levels are normal.

[@marshalltown1991]

Did he just say “females…SORRY, biological females”?

[@dden7670]

1 Reasons You Should Not Supplement With Creatine, possible prostate enlargement.

[@md82892]

Or instead of supplementing with synthetic creatine, you can eat Meat, Fish, Dairy, Eggs which will completely eliminate the need for supplementation. It’s always hilarious to watch a vegan youtuber to promote an essential nutrient that only exists in animal based diet. These type of nutrients is the strongest proof that humans have evolved to eat a primarily meat based diet and we can’t survive on a vegan diet unless you’re dependent on synthetic vitamins and minerals. Go on Simon, it’s fun to watch these contradictions in your nutrition philosophy with human evolution.

[@swites]

Creatine isn't essential because the body makes it own out of 3 amino acids. Just like the cows and sheep you consume make it in their muscles from the grass they eat.

[@billyt9921]

You didnt need to qualify what you meant when u said 'woman' at the 10 minute mark..... we ALL knew exactly what u meant. Dont join in with the pantomime.

[@HarryLlewellyn27]

Creatine is clear evidence we need to eat meat🥰

[@TheProofWithSimonHill]

Creatine doses are typically 3-5 grams, roughly the amount in 1 kg + of red meat so no not really.

[@HarryLlewellyn27]

@@TheProofWithSimonHill not so difficult…

[@MrGeekUSA]

Eat 1-2 servings of red meat a day to get enough creatine only to die of cancer or heart disease before you're 60, duh 🤔

[@PauIdenino]

How come? You don't need to eat meat to get creatine.

[@BellaCups1515]

I think our teeth indicates we should eat some type of meat but I cant tolerate the smell texture or taste of any meat. 😅

[@jeffrey4577]

Red meat has plenty of carnitine. It's the source so just eat meat sillies.

[@TheProofWithSimonHill]

I think you confused creatine and carnitine, and also failed to know that red meat does not have "plenty" of creatine either.

[@jeffrey4577]

@@TheProofWithSimonHill creatine comes from animals! Same thing , eat the source not some pill lol

[@739jep]

⁠​⁠​⁠@@jeffrey4577eating meat doesn’t significantly alter the levels in the body. Meat does contain creatine but much of it is destroyed in the cooking process. Supplementing with creatine allows us to significantly increase the creatine levels in our cells without the burden of eating large quantities of meat and the associated calories.