#87-Rick Johnson, MD: Fructose-the common link in hypertension, insulin resistance, T2D, & obesity?

[@dixiewade8373]

I am in my sixties, was put on an extreme low sodium diet, I had obesity, kidney disease, high blood pressure, insulin resistance, major gout, inflammations, nerve damage, was put on oxygen, pneumonia multiple times. I went on a very low carb/keto type diet. After a year and a half with almost no processed foods and no juice or pop, everything has disappeared, almost entirely. My doctors are stunned, as am I. My husband is healthier than he has been in 25 years. I lost a hundred and he lost 45 pounds and we don't miss all the junk and processed foods and saved huge amounts of money by not going to restaurants. This is all thanks to all of you doctors on these types of podcasts and videos. Sensible, scientific, logical information. Thank you all!

[@KindergentlerMr.Softbelly]

Keep up the new lifestyle

[@tumblingrosesstudio]

Wow, congratulations on your determination and recovery. Be well.

[@HEARTANDSOULOFMINE]

Bravo! As a holistic nutritionist, I applaud your tenacity and admire your courage to go "against the grain" and apply the knowledge you are learning from doctors and researchers who also seek to learn the truth and share it among other seekers of truth. Congratulations achieving wellness and a better chance for longevity for you and your husband's life.

[@robertkraychik1884]

amazing. thank you for sharing this.

[@Texasketogirl]

Congratulations, this is an amazing accomplishment!

[@black_number_one]

I've heard Dr. Richard Johnson being interviewed on other shows, but this Peter guy ask such good questions! And I like how Peter adds in layman's terms so us dummies understand! Excellent job Peter!

[@spek2554]

That is why I am Hooked on Attia.

[@jellybeanvinkler4878]

"This Peter guy!" 💟

[@Mr-hn2bp]

He summaries at the same time. Excellent.

[@jimcausey1674]

In one year, my hs-CRP has progressively decreased from 3.48 mg/L to 0.7 mg/L, my HbA1c declined from 6.2% to 5.6%, and SBP reduced to average 130 mm Hg. The simple plan: no processed foods, mostly vegetables, avoid fructose and minimize salt. Weight decreased from 256 lbs to 220 lbs. My nighttime HRV has progressively increased, resting HR decreased and my reaction: gratitude.

[@NigelBanks]

Wow - I am so grateful for this session. I have avidly searched for information on dietary contributors to hypertension for upwards of a decade since discovering that my uncontrolled systolic was usually in the range 160 - 200 mm Hg. The ground you have covered today has so powerfully fleshed out a conceptual model of the key metabolic drivers that I should seek to manage. So many gaps / burning questions sorted in a single session - thank you so much - 🙏🏻🔆🌼

[@kmcveigh100]

This is incredible. One thing not mentioned (or I missed) is that Fructose metabolism will yield a particular molecule called Diacylglycerol which leads to PKC activation. A few episodes later and Peter is interviewing Gerald Shulmann about DAG causing insulin resistance. Things are piecing together

[@kmcveigh100]

So I re-listened and at around 55-57 minutes, Rick does allude to how DAG might increase in the cell. Although he doesn’t describe DAG, he does mention how uric acid inhibits Enoyl-CoA-hydratase (enzyme responsible for 2nd step of fatty acid oxidation) AND uric acid inhibits aconitase (enzyme within Krebs cycle to move from citrate to isocitrate). Elevated citrate induces fatty acid genesis. Uric acid is a double-whammy.

[@spek2554]

Doctor Attia, I just listened to Dr. Perlmutter being interviewed by Doctor William Davis. Perlmutter retells how he heard your interview with Doctor Eric Johnson which inspired Permutter’s book “Drop Acid”. All of you are remarkable. And it is remarkable how a podcast can enlighten the medical field about fructose. Keep getting the word out. Thanks

[@victoriajones7463]

This is one of the most fascinating &,informative podcasts I have found integrating biochemical, evolutional anthropoligical nutrition & medical science research. Absolutely brilliant!

[@sharicreamer4514]

I'm gonna need to listen to this one a few times. So much info that's new to me, and I want to make sure I'm understanding it correctly. Great chat.

[@fidetrainer]

not sure it needs too much detail, you can go keto with a clear conscience. And/or, if you're going to "cheat", don't take all your fructose and salt at once!

[@KJBtheMosFett]

I can't believe I haven't listened before today. Rigorousness for the win. This is best podcast I've ever heard.

[@daniellejohnston2939]

I love this because it presents all the “why” behind the results we are observing in our culture. The chemistry of our bodies is such a beautifully balanced dance, but when you insert a problem into the mix, everything begins to shift and result in a myriad of multi-organ problems. One change often solves a sea of problems. Thank you Dr Johnson and Dr Attia for this great podcast!

[@chanding]

This is brilliant. One thing I'm fascinated to understand is the intersection of salt and ketosis in this discussion?

[@Michael_Peters]

I began drinking an extra glass of water before meals the last couple of days. I’ve been keto for 3 years and would run regularly. When I first started the keto diet, I’d get the shakes on my runs and have to stop. After reading about increased salt excretion with keto, I upped my salt intake, and my runs were solid again almost overnight. I just upped water intake significantly for the last 48 hours and yesterday for the first time in 3 years, I felt like straight garbage on my run. I stopped at 1 mile and had to walk back with my tail between my legs. It freaked me out bc I’ve felt so good for so long on keto, exercise or not. This morning again, felt terrible and shaky and hadn’t done any exercise whatsoever. Then I remembered what happened with salt and keto 3 years ago. I added some salt to a warm glass of water and felt much better in ~ 10 minutes. I’m no doctor, but being keto seemingly changes the salt/fructose calculus somewhat at least in terms of my physical well-being and definitely my athletic performance.

[@chanding]

@@Michael_Peters add some potassium to the equation :)

[@cherylcheong5616]

How do you get rid of the uric acid?

[@Michael_Peters]

@@cherylcheong5616 Not a doctor and this is just me postulating. I know a carbohydrate rich diet tends to make one's body hold on to salt, NaCl. When you do a low carb high fat diet (LCHF), your body purges ketones through the urine. Those ketones are negatively charged and bind with Na+. So, increasing salt on a keto or LCHF diet means the Na+ isn't staying in high enough concentrations to cause uric acid as a byproduct of fructose and purines. If you're doing the standard American diet, and eating something particularly salty, then drink that extra glass of water before meals because you need to make sure the salt concentration isn't high enough to create excess uric acid.

[@Mr-hn2bp]

@@Michael_Peters Carbs raise insulin level which acts on the Na-glucose-ATPase to retain Na ions.

[@GUIDE_Nico]

20 Years ago. He has been doing the legit research 2 decades ago. Very grateful to hear this! Thank Peter for having him Rick Johnson M.D. on today.

[@johnmarsili4430]

This was Outstanding Dr Attis and Dr Johnson thank you for making me way smarter for over an hour and a half. Keep up the great work for us lay people who are trying to do our best.

[@kodilutv]

Excelent! I listened to this episode twice. Got out extra details the second time. Thank you

[@sidmichael1158]

So how do you eliminate the fructose in your body. Even if you consume glucose it will turned into fructose.

[@Mr-hn2bp]

@@sidmichael1158 The conversion is minimal when the glucose load is low and the body is not dehydrated. Do not get the aldose reductase induced in the first place.

[@iamdedlok]

Another amazing talk! Thanks again Dr Attia and Dr Johnson! Loved the talk and learnt a lot!

[@crothcipt]

I turned back my Gout by quit eating sugar and anything with yeast in it. That was over 10 years ago. (late 30, early 40's). I went on a Keto diet afraid that to amount of meat would bring it back, going on 2 years later no signs of any yet. Ty for the great explanation.

[@dianebonneau2350]

Riveting and fascinating discussion. Many thanks to Peter and Dr Johnson. We may as a species, never come into existence were it not for the ape group returning to Africa.

[@rjhill1972]

Information overload. Thank you for this.

[@edwigcarol4888]

but so sharply presented.. such a mindblowing precision in the how and why step by step.. "Brilliant" as german people say... taking notes... a lot...

[@robertthompson5501]

When I eat my piece of salty beef jerky post workout and sauna I will be sure to drink plenty of water. I am low carb yeah Kiwi is back. Thanks

[@jellybeanvinkler4878]

My ears perked up at the kiwi remark, too! LOL🥝

[@t.c.s.7724]

Excellent program today, sir. The best you've ever brought to your audience.

[@geopietro]

Excellent discussion. Thank you. Early on Professor Johnson stated there was "good epidemiological" data linking higher levels of blood pressure with certain conditions. That's bothersome as epidemiology cannot establish causality. Thank you.

[@fedegroxo]

No statistical method will ever truly demonstrate causality. Epidemiology is one more tool in the toolbox, and refusing to use it because each datum is not as valuable as its counterpart in, say, a clinical trial, is foolish behavior. Epidemiology is the only way to study extremely large sample sizes, and well designed epidemiological studies are sure to further our knowledge about things.

[@geopietro]

@@fedegroxoEvery tool has an area where it is appropriate. Epidemiology and causality are incongruous. Random placebo controlled clinical trials can show causality infinitely more than epidemiology.

[@fedegroxo]

@@geopietro So what's even the purpose of epidemiology, then? There is one, only, and that's helping to establish causalities.

[@geopietro]

@@fedegroxo You are correct to say "helping." A primary use of such studies is to establish hypotheses for further research into causation.

[@mechellespillekom5891]

Wow …. Wow I’ll have to listen to this again! This was so much information that I need to process, and then change up what I’m doing.

[@claudettesechler149]

Thank you for bringing this to the forefront! Another path to learn about and just love the content..where were you during the 70’s and 80’s when I was low fat and vegan? Gee, did I pay dearly for that! Thank you

[@timbadonsky363]

One detail that is a little bit obscure, during the discussion of the metabolism of fructose, the term "AMP-D" is used. Peter carefully explains the differences between ATP, ADP, and AMP, but does not ever spell out that AMP-D is AMP Deaminase. Rick Johnson, earlier in the conversation, mentions AMP Deaminase but from then on assumes that the reader know that (AMP-D) is AMP Deaminase. The critical fact is that AMP Deaminase (AMP-D) is a competing or alternate metabolic pathway from AMP Kinase. Even though I have listened to this discussion several times, that detail wasn't clear to me until after I had seen the relevant diagram from Rick Johnson's book, The Fat Switch. This, of course, is a critical point, since it is clear from the discussion that it is the activity of AMP-D (and the rest of that metabolic pathway) that leads to the excess production of uric acid and so the constellation of bad outcomes collectively described as the metabolic syndrome.

[@m.k.6143]

One of the best interviews I have heard so far. But I have to admit, that the micro management (salt, potatoes etc.) is a bit discouraging...

[@Maria___28]

Great interview. Thanks

[@sidmichael1158]

Why not increase your ampk to inhibit ampd? Metformin and berberine can.

[@arunidhanapala2053]

Very informative. This information you cannot find elsewhere.

[@dinomiles7999]

Great info! Now , plain English for the dummies like me . What should we do to live a healthy and long life .

[@johnt.70]

TL;DR version: Don't eat sugar.

[@umeshchhikara]

Another good talk Peter. Thanks In my recent experiments to gain weight for lean muscle mass I did the following: Firstly, I gained weight by adding sucrose in some form and also added a beer. But not so much of fructose. I added 4 kilos, increased muscle mass, and then finally manage to reduce 3 kg's in a 20 days cycle. Second, which is this time, I gained weight by adding sucrose and fructose. I also had sucrose in high calorie foods like oats/nuts chocolate and via fruit like grapes. Both the days when I had mixed this I felt more bloated and I increased my weight in just 3/4 days. The point of contention here is I felt it this time. I took a week to add same weight last time. I felt bloated this time around and I can visualise the food getting stored than it getting consumed for energy. So yes...I can confirm one thing for sure - its different when you have sucrose or fructose empty stomach where it works genuinely as a source of energy. But the moment you add both on top of your regular meals, even when the calorie intake is same...it stores fat and adds weight faster than over eating your regular food. It could be perhaps because 'metabolic basal rate' works on the food in transition whereas with fructose it could be that it gets stored as fat straight away if we have enough glucose in our system. Another reading for me which is coming through via this is....if it adds weight so quickly then its equally easier to lose fat when you drop both. And therefore it is no sin to have little bit of fructose or sucrose in our diets...its just the management of the two that matters.

[@gard291]

Awesome information, thank you. Please do a show on PAM enzyme and how it activates all signaling hormones via - C terminal correction/snip and add - making them functional. Never new hormones could be present and at correct levels but not at all functional due to lack of PAM activation - Richard Maines and Betty Eiper 40+ years fully funded research on PAM.

[@keithcorodimas8093]

First-rate interview and discussion.

[@chrissuozzo]

Honestly Rick’s book should just be called “Fructose is the cause of Metabolic Syndrome”. We’ve been searching for the primary cause of metabolic syndrome for 50 years and now we appear to have a mechanism that explains it. If true that is Nobel Prize territory and will likely save millions of lives.

[@JohnKenney3]

Great interview. So eye opening. Thank you both very much!

[@chaz6399]

Here's a question I'd like answered (relative to discussion at 1:22:10): Does aldose reductase gene expression get switched off on a long term fast? And if so, how long of a fast is necessary?

[@cdixon1108]

Best talk on this subject EVER. Thank you. 👍🏼👍🏼

[@aaronkelly2414]

Great interview

[@louisebrown7526]

Thank you both. So interesting and informative!

[@KindergentlerMr.Softbelly]

Answered a pressing question for me. Why does my blood sugar stay up and ketones down even when fasting? I consume a lot of salt when fasting, plenty of water too but lots of salt as it keeps energy up. Salt is facilitating the conversion of fats to sugars for me. Whole audio was excellent. I get extra salt taking bullion with butter in hot water, bullion is basically flavored salt. My weight and blood pressure are great so I’ll keep it up. Sugar levels are not high just higher than expected while fasting and ketones lower than expected in ketosis.

[@Dermsurg1]

Fascinating ! Peter, did you mention that Richard Johnson has a financial interest in the development of FRK inhibitors? He does...

[@victorcs_]

1:00:10 that's an important take away.

[@petercat926]

Simply put. Love u! ❤ Fight the fight🎉

[@MaxRevitt]

Interested to hear about fructose intake during sports!

[@sc4332]

Does anyone know if coconut water is ok? Say 250ml or less.

[@johnepyttesr8947]

Thanks for covering fruit consumption!

[@robertos4172]

Fascinating and insightful.

[@M3galodon]

The more I learn the more sense keto and the carnivore diet makes.

[@Steffystr8mobbin]

I'm so torn about it- ketogenisis is hard on the liver as well as cortisol driven and also may downregulate glutathione production. I think somewhere inbetween is probably optimal, seasonal or cyclical keto if you will. Check out Chris Masterjohns videos on ketogenesis.

[@M3galodon]

@@Steffystr8mobbin I just feel so good and alive when I'm on the carnivore diet. By contrast, I feel like I'm sloth in mode on my regular diet. I always wonder how can my body react so differently. Could it be that we have different digestive systems just as we have different blood types, different sleep patterns (early birds vs night owls), etc? Some people feel great on a vegan diet and not nearly as good on a carnivore diet and the other way around as well.

[@TerriblePerfection]

@@M3galodon In my opinion, vegans can only feel great for a while. It's not a sustainable diet because we need animal fat to thrive, and the oxalates in vegetables are harmful over time.

[@great-garden-watch]

I don’t even know anymore how to avoid fructose. I check every label and mostly don’t even eat things that have labels, and finding out my body can produce fructose i just don’t know what to do. I don’t eat sugar and very very few carbs, like 5 crackers if i have cheese. Usually under 30 grams of carbs.

[@timbadonsky363]

It sounds like you are doing the right things. Rick Johnson notes that the body can produce fructose, but it does so from existing glucose and in response to specific short-term states, like a high level of sodium in the blood. If you only eat small amounts of fructose (and or, sugar) and make sure to drink water before meals, it seems clear that you are doing all that you can and that you likely won't often be in the state when your body produces fructose.

[@sidmichael1158]

Please Dr.Attia do studies and research on this uric acid and fructose and gout.

[@hidaven]

Nothing better than a qualified intelligent interviewer (seeking personal growth), having an inquisitive conversation with another intelligent expert. We are lucky to be flys on the wall irrespective of Peter’s big apple fetish : )

[@jaym9846]

24:50 So we were fruitarians? Then cold climate selected the ones with a genetic mutation that allowed fructose to trigger more fat storage?

[@sherifgerges9316]

I sincerely wish that Peters channel took 5 minute snippets from these interviews and started posting them. A lot of times, I'm not interested in the entire podcast…

[@hillsview455]

Very informative. Thank you very much.

[@henrybird26]

What makes the sweet go away in soft drinks? It's the salt.

[@jenniferflowers915]

Great information. What happens to the purines that do not become uric acid anymore, under allopurinol? How are they trsformed and eliminated? Thank you

[@Saltlick11]

terrific, learned so much.

[@robinengland5799]

After reading Dr John Yudkin and Dr Lustig along with this information, I feel that I am now armed with the knowledge to lead a wonderfully healthy lifestyle! Thank you for providing this life changing information!

[@edwigcarol4888]

But this makes more difficult to see loved ones ruining their health with "healthy orange juices".. as if they were killing themselves very slowly...

[@robinengland5799]

Very true, and it is very hard to keep telling your friends and family you don’t eat the things they eat!

[@jeffrey4577]

Why does UA increase after a day or more of extended fast then lowers after lessor fast?

[@alfredvincent13825]

Just started getting gout in the past year. And I’ve been Keto during that time. Any suggestions on eliminating it without continually taking indomethacin when it flares up? I take Allopurinol daily but it doesn’t seem to help.

[@TerriblePerfection]

Go carnivore

[@HEARTANDSOULOFMINE]

Are you doing strict keto? Many of these supposed keto diets and products are NOT true keto.

[@sidmichael1158]

Sugar glucose and salt can be converted to fructose?

[@karneymac]

Fantastic informative exchange. TY!!! What I don't fully understand is why the body manufactures fructose in the first place. I get that the body may need to hoard energy and that FR facilitates that but wouldn't glucose be a more metabolically efficient way of doing that?

[@jellybeanvinkler4878]

Fructose was what was available while we were evolving. Fruit. He said the apes were pretty much fructarians.

[@RuiBarreiras]

Awesome chat!

[@sidmichael1158]

01:03:00 fasting.

[@TheBwithers]

I thought insulin resistance was caused by excess fat in diet. That is how they induce in the lab

[@Park-Terrace]

No

[@sidmichael1158]

How do we lower our uric acid without taking medicine?

[@Iraq793]

Eat less meat. Reduce purines in your diet.

[@robertp5998]

Awesome info

[@kimmeyer370]

Wonderful podcast!! I'm wondering about Allulose. It's structurally similar to fructose. Will it trigger the same metabolic pathway as fructose? I love baking with it, but will stop if it's causing me harm. Thank you!

[@markcredit6086]

Once again an intelligent guy stepping out of his domain all this ape talk and evolution it's just hypothetical conjecture there's no tie there at all.

[@PBoss0]

Peter Excellent interview as usual. Why is this information not being disseminated to all physicians or the public? The knowledge would have a profound effect on our health & health care system. Get the word out! Clearly what we eat (diet) is our medicine or our poison !

[@lisafitzpatrick5800]

So thrilled with the punchline on fruit! But dates are my sweetener of choice. What say you?

[@yvonnewagner9833]

Dates are not a good choice (exceedingly high Glycaemic index). Get off all sweetening foods. They are truly not a necessary part of human nutrition.

[@vayasindios3311]

I drink water with fresh lemon everyday. About 3 lemons per day. I don’t know if that’s a lot of fructose

[@josephrzeczycki8642]

It isn't. 3 lemons is very low fructose.

[@joaosoares9591]

The best ever.

[@josemiguelmandolesi4199]

MASTERCLASS 👏👏👏👏👏👏

[@longshanks5531]

You can have fruit and honey and not develop NAFLD and not develop diabetes, all in moderation

[@sidmichael1158]

Ampd vs ampk @ 48:00

[@mikerichardson4266]

Nothing was mentioned about eating meat the last 2-3 million years . Without the uric acid we could not walk upright as what happed to our ape cousins. We were creating huge amounts of uric acid. Uric acid is essential to immune function. I have reviewed over 3,000 papers

[@chaz6399]

Somebody tell Robert Lustig to update his slides. He's still telling everyone that fructose is metabolized exclusively in the liver. This information is going to complicate his story.

[@stargazerbird]

Interesting but I felt he lost his way somewhere among the weeds. Seems like all the hyper-palatable foods cause this pathway to light up - we all love salty sugary and umami foods. We already know that hyperpalatable foods are the problem. Maybe he is describing the mechanism? I think this needs more clarity.

[@dianechilds1857]

Is this related to seasonal depression? My psychiatrist laughs that I hibernate like a bear.

[@kabropatai5476]

Thanks, Peter and Rick, I love the everything in this interview . I am following all of your conversation and interviews, all of them are helping to those the have long term health problems. All of your comments are practical and useful. Could you please let us know why keto diet is causing gout. Keto diet is low carb 5% moderate protein10 to15%? I am not agree wot Rick to use Splenda for sweetener, this will damage your children's normal growth even damaged there brains. Splenda is dangers to plants human and animals, please respond to my questions ASAAP.

[@leeyost9917]

Sucrose Glucose Insulin resistance heavy metals atherosclerosis HBP HEART 💔

[@beingme3302]

Is salt to fructose a one way process or does it work the other way too, say fructose to salt if one say, had a shortage of salt intake? Is this enzyme driven of a chemical reaction? Sounds enzyme driven. Not certain. Curious because of recommendations of "low salt" eating regimens. Thank you. RetRN.

[@eruiluvatar236]

Shouldn't work the other way. Salt (or rather sodium) increases the activity of an enzyme that converts glucose to fructose but the sodium itself remains unchanged. Sodium being an element can't change into anything else nor anything can be changed into sodium, that would be a nuclear reaction!.

[@edwigcarol4888]

@@eruiluvatar236 even the sun wouldn't be able to do it...

[@kbkesq]

Fructose sounds horrible so what about whole fruits?

[@kbkesq]

He answers it at 1:40:00. Fruit is healthy and berries are low fructose. Grapes are higher in it.

[@Park-Terrace]

Eat low glycemic fruits

[@sonwil705]

42:00

[@KenJackson_US]

*Fructose is Toxic!*

[@WolfieWoofWoofMeow]

As usual, Peter Attia constantly interrupts and misunderstands numerous times. Quite rage-inducing. If he would shut up and let someone fully explain something and tell it the way they want to tell it, THEN ask his questions or recap, his interviews would be shorter and 10,000% better.

[@sidmichael1158]

No talk about fasting? And uric acid?

[@foodcrash9450]

Sid Shut up with all your annoying questions. Why not be gateful for the service you have gotten and then search yourself for the rest. Or at least ask nicely.

[@southpaw7426]

How fortunate and miraculously coincidental, that a genetic mutation was just in time to save the apes. . Evolution is not supposed to work this way, although the environmental pressure ad hoc patch has provided a convenient work around for the idea that RANDOM mutations enable survival.

[@CHEZZYNIPSTERZ]

AMAZING THANKS not AMA zing

[@Indieauguste]

Bullshit talks.

[@78cheerio]

Suddenly the starch based diet proponents lose credibility!😀

[@stargazerbird]

I don’t know - they look slim and healthy to me.

[@kerryjean2223]

There should be a law made to make everyone read Gods living word the Holy Bible. Even if they do they won't understand it unless they obey Jesus the Christs directive to be 'born again' of water and of the spirit. Water is baptism by full emersion at an age of understanding (not as a baby) for the forgiveness of previous sin and spirit is to receive Gods gift of the Holy Ghost and Power with the Holy Bible scripture evidence of speaking in an unknown tongue as the spirit gives utterance just like on the day of Pentecost. Evolution is a theory never to be proven. God Created every thing x Apes are NOT our ancestors lol.

[@neorich59]

You clearly don't understand what a "theory" is, a common issue among fundamentalist "Christians." I would suggest you read up on the subject from sources other than your book of fables. Evolution is most definitely proven. Not only are apes your ancestors. You ARE an ape! 🤣🤣 Never mind, I would agree with you that everyone should read The Un-Holy Bible. The nonsense within should be enough to convince anyone with half a brain that the Christian God, as Thomas Paine pointed out hundreds of years ago, is more like a "demon" than a God. If He is a God, He's a particularly selfish and wicked one. In fact, He's *so* wicked, it's a wonder there's a need for Satan. The idea that you think that there should be a law forcing everyone to read the Bible speaks volumes. It makes you sound as fanatical (and about as rational) as the Taliban/Isis/Al Qaeda. BTW, they think that *their* God trumps yours. I'm tempted to say God help us all, only God never does anything, just sits on His fat, lazy ass allowing all of the evils in the world to occur, without lifting a finger. So, what's new?

[@emh8861]

Apes eat bananas 🤣

[@simev500]

It makes sense for the symbiosis of plants with animals. Animal foraging for fruits just as season turns cooler, and plants generating their fruits for the moving animals to disperse the seeds passed unaffected through their digestive tracts to continue the next generation. 🫐🍒🍓 🐿🌱

[@wernerbauer2652]

I have elevated uric acid levels, kidney function is shite, I don't consume fructose or glucose, or that many carbs at all.......btw over 3 years I've reversed diabetes, fasting insulin levels are awesome, HbA1c really good, fasting glucose fantastic, lost 65lbs and workout most days, but BP is higher than ever!.........so work that out experts

[@emh8861]

Maybe your having too much protein?

[@gabrielekennedy6123]

So informative. Thank you.

[@timmothyburke]

I am really disappointed about the gloss over on the persistence of this liver enzyme that converts glucose to fructose. What exactly does it mean that it’s persistence am I stuck with this for the rest of my goddamn life or what?

[@elisafrye2115]

🥳This is one of the most thoughtful, valuable interviews I have ever heard-and like most people here, I have long been fanatic about listening to or watching anything regarding dietary wisdom for those of us now successfully. fighting our wonky sugar metabolisms. 👍😋 AND OUR HIGH BLOOD PRESSURE! 😱

[@marynguyen6417]

Fascinating, fascinating! I am going to replay this multiple times to connect all the dots those are spinning in my head right now :-)! Absolutely love this podcast!!!!

[@SteveHazel]

everybody kiiiiiiiiiiinda needs to know all this !!! lord knows my doctor doesn't...

[@Chinese080808]

My Dr ( a kind and compassionate fellow, god bless him!) flat out told me he won't check my D3 level because it's useless and won't affect my health either way amount a handful of other minerals, etc 😬

[@sidmichael1158]

@@Chinese080808 time stamp where they talk about vitamin d?

[@Chinese080808]

@@sidmichael1158 I'll listen again I don't remember if D3 was covered but I brought it up to demonstrate that some doctors are ignorant of nutrition.

[@sidmichael1158]

@@Chinese080808 here's the thing you won't be able to absorb vitamin D if you're insulin resistant

[@Chinese080808]

@@sidmichael1158 good to know.

[@googoo7750]

Ok Can you explain the fact hunter gatherers eat more protein than western counterparts but don't suffer from gout? Data and science is nice but can be manipulated into gaslighting and unfortunately to become a doctor you have to repeat the dogma so many times you start to believe it. And if uric acid is bad why do we reabsorb most of it?