Action Potential in Neurons, Animation.

[@Alilamedicalmedia]

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[@almasfatma8929]

remember the word NOKIA Na Out K In via Atpase 3 ➡ 2 ➡1 3 sodium out 2 pottasium in with 1 use of atp

[@hidaayattv]

Always remember the word 'INK', I : Inside the Cell. N : Negative Charge. K : Potassium. ❤️

[@SantoshPatil-ht1cd]

👍👍

[@lara.lara0]

Ty

[@neha17498]

Thank you for this so so helpful and easy to remember 🧡

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Ok ola hu uber

[@blueblood-_-]

Yes bish

[@riddhipatel4747]

Literally saved our lives! Explained in minutes what was confusing us for hours. Thank you so much and keep up the great work!

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Riddhi Patel u mean mentally

[@anyasin9142]

I agree

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😬

[@halaa9319]

facts

[@Kartik-xw7yt]

Actually..!

[@mellisaalvarez4859]

I just learned a whole week of lecture in 6 minutes. Thank you!

[@Sanvideshmukh6118]

Yup....Mee 2

[@izarscharf7845]

More like 5 mins of lecture ...

[@NancyLee-u5u]

i half fall asleep and half contemplate jumping out the window during class lectures lol

[@ManshDeeprul]

Are you alive

[@manuelarturoalosillarodrig9553]

0:18 ACTION POTENTIAL: A brief reversal of electric polarity across the cell membrane. 0:44 RESTING MEMBRANE POTENCIAL RMP (neuron): -70 mV (cell is more negative in the inside.) 1:23 A neuron is typically stimulated at dendrites and the signals spread through the soma. 1:28 DEPOLARIZATION: Excitatory signals at dendrites open ligand-gated sodium channels and allow sodium to flow into the cell -> makes membrane voltage less negative. 1:49 Influx of sodium produce a current that travels towars the axon hillock. 1:49 If the summation of all input signals is excitatory and strong enough when it reaches the axon hillock -> action potencial is generated (travels to the nerve terminal). 2:08 Axon hillock: "trigger zone" (where action potential usually starts -> voltage-gated ion channels concentrated). 2:27 Voltage-gated ion channels open at some values of the membrane potential and close at others. 2:45 THRESHOLD: -55 mV -> Minimun required to open voltage-gated ion channels -> action potential generated. (Na+ channels open quickly / K+ channels open slowly) 3:07 As sodium rush into the cell, the inside becomes more positive (depolarization). 3:18 The increasing voltage in turn causes even more sodium channels to open (positive feedback) -> Rising phase of the action potential (polarity reversed). 3:37 As the action potential nears its peak, Na+ channels begin to close -> K+ channels are fully open. 3:47 K+ rush out of the cell -> voltage returns to its original resting value (falling phase of the AP). Na+ and K+ have switched places across membrane. 4:08 HIPERPOLARIZATION: Negative overshoot (K+ gates close slowly -> K+ continues to leave the cell a little longer). 4:15 RMP is restored thanks to diffusion and Na+/K+ pump. 4:34 REFRACTORY PERIOD: During and after shortly and AP is generated, it is impossible or very difficult to stimulate that part of the membrane to fire again. 4:40 ABSOLUTE REFRACTORY PERIOD: from the start of an AP to the resting membrane value. -> Na+ channels are open and then inactivated -> unable to respond to any new stimulation. 5:00 RELATIVE REFRACTORY PERIOD: Lasts until the end of hyperpolarization (K+ channels still open) -> difficult to membrane to depolarize. 5:38 El potencial de acción se propaga solo en una dirección (debido a las propiedades refractarias de los canales iónicos). 5:41 Solo la zona no activada del axón puede responder con un PA; la parte recién activada no responde hasta que el PA esté fuera de su alcance. 5:53 An action potential generated at the axon hillock usually travels down the axon and not back to the cell body.

[@Unknown-zc2nv]

Really thanks for this summary ❤

[@saraelsayed1850]

Thanks

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@@Unknown-zc2nvits not him who made it its in the description haha

[@PiyushKumar-el3ew]

Aur bhai aagye yakeen walo...🤣🤣chalo like kardo to +4 pakke

[@GulsonAraBegum]

Samapti ma'am kesa samjhati hai?

[@PiyushKumar-el3ew]

@@GulsonAraBegum itna ki ye dekhne ki zarurat nai padegi..🤌🔥

[@brittanyjin4723]

One of the best explanations I could find. I was really confused about the pumps and refractory periods but now I understand what my text book is trying to explain.

[@IbnuHussein-w5l]

😂

[@CristianDiPuorto_glockshock]

As an engineer I couldn't find a satisfactory edplanation on depolarization; thanks to this video It now makes much more sense. Thank you and keep up the good work!

[@Jasewpo]

I shed a real tear watching this video... 10/10 excellent job

[@mansidraw]

this is undoubtedly the best explanation of the action potential!!

[@thelabadabada]

This is the most accurate explanation of Action Potential in Neurons .... compared to the other videoeS! thank you!

[@Mouthymensch]

THANK YOU THANK YOU THANK YOU!!!!! When my professor explained this in class I was so confused but this helped me actually understand it!

[@Jossha7]

A video made years ago just saved me☺️☺️. Alila the best

[@piumisathsarani6044]

this is the only video that clearly explains about the action potential. thank u so much💖

[@josephdesensi1919]

Absolutely relieving! Great explanation that was clear and unlike every other explanation, not too many extremely complex words were used in one sentence which is the giving up point for most people. Thank you

[@mohammedomar8616]

This video is sent from heaven😂 Thank you for this amazing explanation

[@rishankuparrangslang3802]

THANK YOU SO MUCH! i wish they'd just use these animations for lectures as well, would make our lives so much easier.

[@Alilamedicalmedia]

Thank you for your comment. In fact many universities and colleges use our videos for lectures and on their online learning portal. You can certainly suggest to your teachers :)

[@hiraafzal6208]

@@Alilamedicalmedia yes! Our physiology teacher use and recommend us too to watch your videos

[@sakshipriya9864]

Thank you a lot for this animation .It help us to understand neuron work easily​@@Alilamedicalmedia

[@michellekristen7540]

The most accurate video I've seen. I wish it talked about sodium's inactivation gate though.

[@Alilamedicalmedia]

Thank you, we will keep that in mind for future updates.

[@archanaraheja2231]

Michelle Kristen *Hmmm*

[@leilaniahkoi]

I have been struggling for weeks and in just a few minutes you have eased my understanding of this specific process. You have given me hope to pass my test. I 100% appreciate this awesome video. Thank you! Thank you ! Thank you!

[@Alilamedicalmedia]

Glad we could help :) Good luck with your test!

[@ranag8973]

Balle balle🕺🕺 samjh aa gya oye😍😍😌😌😌😌😀

[@11Tyler]

I have a huge Anatomy final tomorrow and this video was just what I needed. Excellent job. Can't wait for your future videos.

[@und3rcut535]

why do you lean this in anatomy this is physıology

[@Alilamedicalmedia]

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[@Ethan_asoldier]

Best video on KZbin regarding this topic

[@supriyasharma8260]

Amezing animation❤❤

[@drabdirahmansaladibrahim4602]

One of the best animated mechanism I saw of AP Well done

[@elbeatsofficial177]

Anyone doing medical physiology in 2024??🙂

[@مُشرقة-ب9د]

Me 😭

[@esq8]

Thanks! My notes were confusing. Couldn't figure out what was happening with K and when it was leaving the cell. 2 hours of reading and struggle solved in 6 minutes. Sheesh! Thanks again!

[@nopenope6909]

Ah yes the good ol' Axon ʰⁱˡˡᵒᶜᵏ

[@theambrosius105]

Lol

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I was looking for this comment, thank you.. I can rest easy now.

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Lol

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🤣

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Yaah 😅

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One more sapola

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Hnn g😅

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Does she teach well?

[@samruddhibansode8097]

The best animated explanation ever👍🙏...This short video made my work lighter

[@skawah1995]

Most helpful video I have seen so far. Thank you!

[@indigorulz]

An hour intense class covered in 5min with good animation! Good job..

[@analien7458]

This is SO WELL EXPLAINED thank uu

[@mawienmajock4742]

The topic which took me two weeks to understand is now understanded in just a few minutes.

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Super explanation....💥Arjuna here ♥️..

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Me

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Me😂

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Arjuna

[@Amnashahab.01]

hey u got a new subscriber.....keep up the good work and thanks alot for such an informative vid 🖤

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Very well explained with supportive visual animation. Simplified and brilliant. Had to subscribe :-)

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I wish I would have watched this video two days ago it would have saved me a lot of headache! AMAZING explanation! Thank you so much :D!!!

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Awesome work thank you 😃😃😃

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Aagye arjunaaas... 🫠

[@EdaLish-c7z]

Great explanation

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SAPOLA ARMY ATTENDANCE 💗💗💗

[@Melo-wy6ki]

After watching lots of videos about action potential really when I exhausted that time I decided to watch this last video really this video helps me lot and ur explanation and video just amazing thanks !!!!

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Zoology is often confusing as we cant do any experiments in human body but you people explained it in such a precise manner that words cant reach to appreciate it. I suscribed your channel One suggestion please pronounce certain words in such a manner so that Indians can also understand.

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Sir, u r a blessing for us students

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Clear all the concepts...thank you very much...🙏🙏🙏

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You’re video was a life saver because I have my exam soon and this section always confused me.

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Thank you so much. This is the best video that I have found so far for my class.

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Best explanation ever one can get 👍👍👍

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Thanq...sooo much...u made it very clear to understand in just few mins...🤗🤗🤗✌️✌️

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Nice and useful videos for our class. Thanks!

[@prateekfaujdar5847]

How hyperpolarisation prevent neuron from another stimulus

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This lesson was one of the most difficult lessons in school. I did not know anything about it. After watching this video, I became able to solve all the questions on it, even those that are not in my approach. Thank you for this useful video. 🤍💫

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Wonderfully explained thank you

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[@Alilamedicalmedia]

Thanks for watching!

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Well explained.Thanks for sharing😍

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Thanks from Uganda

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You are a real legend like OMG. This literally taught me what i was struggling with. Thank you

[@Alilamedicalmedia]

Thanks :)

[@anvayaiyer5614]

Thank you so much for this. I will forever remember this favour

[@prateekfaujdar5847]

Please tell how hyperpolarisation works

[@anvayaiyer5614]

@@prateekfaujdar5847 4:06 if the timestamp. Basically, potassium channels are slow to open and close. Right after the falling phase, the potassium channels remain open for a while longer due to which more potassium ions leave the cell. This results in a the cell becoming slightly more negative than what it was in it's resting phase. This is called hyperpolarization. Tell me if it cleared your doubt... 🙂

[@kajalpandey5021]

It is really very very helpful. Thank you

[@smitaparekh8443]

Best vdo to clr action potential .. thank you..

[@dimpideepika]

This taught me so much regarding conduction of action potential thnq u so much for sharing 🙏

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Anyone from yakeen here??

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Apko smjh nhi ata kya???yakeen may?

[@iyaylim2989]

Excellent explanation, great work!

[@Alilamedicalmedia]

Many thanks!

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Thanks for sharing such a Great video dear..... I was very confused but this animation really help me to understand the concept... 👍💕

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Explained well sir

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This is so clear!Thank you

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Excellent animation video

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Best lecture ever

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this is what we needed.☺

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It was phenomenal 👌

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So comprehensive and fluid!! Thank you.

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You are blessed inthe name of jesus ameeen❤❤

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best explanation ever !

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Very well explained

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I finally understand now. Thank you for this.

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its really good. Easily understandable. Thank you.

[@Alilamedicalmedia]

Thank you for watching!

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This is the way to teach Thanks dear sir