Advanced Glycosylation End Products and Diabeteic complications

[@hangcai]

This should be advanced glycation end-product instead of glycosylation. this can be a huge misunderstanding but thank you for putting these together :]

[@animatedbiologywitharpan]

Thanks for your feedback it would help to improve the content

[@tictactoj]

AGEs are Advanced Glycation End Products? Not glycosylation? This is very misleading.

[@taiyabkamaal681]

Very well explained! Thanks and best wishes!

[@animatedbiologywitharpan]

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[@pipoviola]

AMAZING EXPLANATION! Thank you very much!

[@animatedbiologywitharpan]

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[@dylanmccarthy8729]

So surley the answer to ending all disease and cancers is to be on a zero carb. (Zero glucose) diet especially as its not essential for humans to live ?

[@magicf7076]

Yes. Zero carbs would be optimal. But seasonal fruits are no problem.

[@BobSommers]

Very informative. Thank you.

[@animatedbiologywitharpan]

Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8& You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

[@gabyfridman7475]

Excellent !!!

[@animatedbiologywitharpan]

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[@cutregia1121]

Very helpfull , thank so much. Could you please share the pathofisiology AGEs picture that you draw?

[@animatedbiologywitharpan]

This is chargeable ($2). If interested please email us at [e-mail]

[@StayExtraVirgin]

Very very helpful and informative, thank you Keto Diet for Life and Intermittent Fasting, Water Fasting :)

[@pritigedam2589]

Excellent sir. Can u explain about Protein kinase pathway and Hexosamine pathway in diabetes

[@عمر_فاروق]

Thank you so much ❤

[@animatedbiologywitharpan]

You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

[@giridv9303]

Do AGEs have a defined life span? If so what is the life span? Or do they stay endlessly in the body? Thanks.

[@animatedbiologywitharpan]

Very nice question. The persistence of advanced glycation end products (AGEs) in the body can vary depending on several factors, including an individual's overall health, diet, and metabolism. AGEs can accumulate over time and persist for a long period. Some AGEs can have a half-life of weeks to months, while others can persist for years. Reducing the consumption of foods high in AGEs and maintaining a healthy lifestyle can help mitigate AGE accumulation in the body. If you have specific concerns about AGEs and their effects on your health, it's best to consult with a healthcare professional for personalized advice.

[@Digitalhue]

Hello Could you share the reference material from which you got this ? Thanks

[@animatedbiologywitharpan]

Lehningers biochemistry and Harper's biochemistry book

[@bobcocampo]

How will fasting help glycation?

[@wackymontederamos]

So you mention that this is T1 diabetes right?

[@guillermoasmar9555]

excellent thanks!

[@bobcocampo]

Are you suggesting to be in carnivore diet?

[@animatedbiologywitharpan]

Not at all

[@lucaschancho]

Very good Video! Could you please, provide the references that you used in this class?

[@animatedbiologywitharpan]

Glad to hear that it helped you.. give me your mail id where I can share the material

[@aishaaltabbaa3375]

can i please get them too [e-mail]

[@markwatson1955]

Arpan, I really appreciate the information you have provided but I am however concerned. Aside from the absolute focus on blood sugars and the outcomes of this, there’s another issue that is seemingly never covered or addressed, except by a few highly qualified PhDs and medical professionals, clinicians included. I allude to an assumption that is quite general. That all diabetes is due to insufficient insulin production and presence in the blood. And, Type I diabetics as well as Type 2 diabetics are the same and are treated the same way. This is a medical fallacy! T2 diabetics can have blood insulin levels that are equal or greater than the average. What is not considered is the deleterious effects of chronically elevated blood insulin on body systems, at the same time as blood glucose is causing it’s own issues. Hyperinsulinemia is a real disease. I believe it is something you could have mentioned in this otherwise short and excellent video.

[@animatedbiologywitharpan]

This is a elaborate view. Thanks for this kind of constructive criticism. I would love to incorporate these suggestion in future detailed video.

[@animatedbiologywitharpan]

I appreciate the fact that diabetes is a very complicated disease.

[@jez770]

Thank you, very helpful :)

[@animatedbiologywitharpan]

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[@anarky4321]

its GLYCATION - glycosylation is a totally different thing

[@garyscott8469]

Quite correct. Just as protein carbonylation is not the same as dicarbonyl stress

[@Omeostatica]

The title is wrong glycation is different by glycosilation.

[@bobbylee2853]

I think so too.

[@drSJV]

Glycation is a non-enzymatic reaction and glycosylation is an enzymatic reaction.

[@lenatan16]

thank you so much! new subscriber!

[@animatedbiologywitharpan]

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[@hazelvergara4062]

In Type 1 Diabetes, there is no absolute insulin being produced by the beta cells of the pancreas. please rectify the content of your video.

[@animatedbiologywitharpan]

Dear Hazel, nice that you took time to comment.Apperently we might think all the pancreatic beta cells are dead due to autoimmune attack.But this idea is not so true ,even in severe cases of T1DM 90% cells are dead but some are always there.Moreover all our hormonal system are homeostatic system and some insulin level is always there.thats why I carefully used the phrase insulin level is pretty low and explained Type 1 diabetes occurs when some or all (point to note)of the insulin-producing cells in the pancreas are destroyed. This leaves the patient with little or no insulin(point to be noted).In general I make my contents after reading fundamental textbooks and all current articles ......so you can count on the content quality.

[@animatedbiologywitharpan]

If you want the references I can surely forward it to you .

[@kylemcmenamin3558]

Contrary to popular belief this is not the case, in a recent British study, researchers found that even after 50 years patients still had active beta cells in type 1 diabetes, using technology to detect even lower levels of insulin than was previously possible.

[@animatedbiologywitharpan]

@@kylemcmenamin3558Mcmenamin thank for clarifying.....by this discussion all us learn new things.....thanks for taking time out to comment.

[@dtrAnxiety-sw8ef]

It is glycation not glycosylation kindly check

[@animatedbiologywitharpan]

Yes it's a mistake from my side