The Brain's Hunger/Satiety Pathways and Obesity, Animation

[@Alilamedicalmedia]

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[@GoodDr.]

Nice video, and I’ve learned a lot, Access to mental health services is crucial for addressing the emotional toll of obesity.

[@TTbelis]

The videography of this video is great, explaining the connection between hunger regulation and human physiology parts like brain low-level circuitry communication with the digestive system. Easily understandable content.

[@alinaelperin8932]

I am on obesity medicine doctor and this was accurate and easy to follow. thanks!

[@asenanar-sw4tn]

Im confused about leptin, why kbese people have low leptin if it depends on fat percentage?

[@10-anindyasundarghosal_7_h2]

Excellent illustration ,very effective for us . Many many thanks

[@rpan5441]

Graphic presentation was perfectly balanced with body mechanism and in-depth research. Thanks Ali. 👍

[@jackbell1306]

@2:38 "insulin is a hormone produced by the pancreas and is released into the bloodstream upon food ingestion" - this statement is oversimplified, and disregards the fact that fat in particular does not independently stimulate insulin secretion (Nuttall & Gannon DOI: 10.2337/diacare.14.9.824). Carbohydrates and proteins produce an insulin response (carbs much more substantially), making the recommendation of a low-fat diet unusual. Are you able to cite any studies that support that recommendation?

[@Fuphu]

I know this is three years old and I’m no expert but I believe high fat diet can cause insulin resistance over time as fats block insulin receptors causing the glucose transporters to not fulfill their functions properly. I am just saying this off the top of my head from what I vaguely remember when I was studying about metabolic syndrome. there’s many more potential ideas I have regarding the topic but I’m not confident enough to mention them here

[@johnsharnetsky9559]

Pay attention to this video. I've changed up my food by taking in account what my gut biome wants as well as myself. I went heavy on eating fiber, prebiotic and probiotic. No pills, just food. This is definitely a change from my normal eating habits. The results blew me away. My sleep has never been better and after a meal I'm completely satiated. My overall hunger went away. There's no desire to snack. Other results... My body's inflammation is gone. My mood is optimistic. Eat for yourself and eat for the little guys in your intestinal track. From there life will get good very quickly.

[@ouivalerie]

She said not to eat much Steak and Cheese, or other saturated fat food. She didn't say probiotics, prebiotics and fiber do this. You didn't say you stopped the saturated food but, I think the gut biome regimen did it for you. She didn't mention how this clears out inflammation but for sure it does.

[@DrMag-fn7hc]

It seems that you didn't pay attention to the video. She didn't say what you said!

[@elliewilson3914]

thank you for such an incredible explanation. Thank you so much for giving the time to do this video especially when you're doing a bioscience degree!!! 🙏🏻🙏🏻🙏🏻

[@joonluv4317]

thank you so much for this video now I have a clear image of the whole process

[@GoodDr.]

Thank you for the information. Weight bias in media and advertising perpetuates harmful stereotypes and unrealistic beauty standards.

[@grai]

I wish they had given us a bit of hope and explained how to restore the hypothalamas to it's proper state by eradicating the inflammation

[@ouivalerie]

In this video she is saying saturated fat (steak and cheese) is going to inflame your hypothalamus so leptin won't release to stop your hunger. Keto claims you can have bacon and 4 eggs every day. They claim they stay skinny. Someone don't know what's really going on. If the "hypothalamus needs to be cleared of inflammation" it's not proved at all here. I don't know what tests there are for this. Could be candida doing that hypothalamus inflammation from the sugar from eating ice cream, sodas....Most people say it's insulin spiking the major factor in insulin resistence but the video seems to talk about leptin resistance, where it won't release due to inflammation. Leptin shortage I seriously doubt comes from saturated fat causing hypothalamus inflammation. People are fat because they are insulin resistant. Insulin no longer moves things into the cells because the pancreas is worn down, clogged or whatever. Leptin is just about hunger control. People do lose control and overeat. It's a fascinating subject but, I don't believe this video has it figured out. The inflammation I think comes from candida fungus. The stuff they used to give castor oil for back in the days over a white coated tongue. I ate nothing for 10 days and lost 10 lbs. Next 5 days I ate about half a pound of meat and cheese one meal a day so not to overspike insulin and be on keto. I lost zero lbs for 5 days. I went back to eating nothing and lost 10 more lbs the same way, 10 more days of nothing. Then I went looking for energy something serious and trying Braggs nutritional yeast because they say B1 does the trick and it's loaded with that but I had to add olive oil because it's too dry. Worked a little so far. I can sit up and walk around the yard. One issue. Old age. More people love a 30 yr old, than a 65 yr old in the USA. A fat 65 yr old is worse. Now she's saying the brain don't respond due to inflamed hypothalamic neurons cause leptin not to release so I think I'm not full. I believe the inflammation was candida. When my tongue goes red after a fast, I'm stuffed if I eat one grape. I used to be very full with a 1/3 small tub of cottage. Recently I want 2 tubs. I do get full eventually but that's too much cottage cheese. Something has changed in me. I was never satisfied so I got fat. I was eating mostly fruit and cheese, and fish, potatoes, yogurt and ice cream and butter for the potatoes. Leptin don't probably work in me, but I think it's blocked with the candida showing on my white tongue after I ate ice cream for 2 months, and I haven't dont that ever before, generally I hate ice cream so now I need a lot of probiotics. So I went on a fast and this is the FIRST water fast I ever didn't get a clear red tongue in 10 days. It's 25 days later and my tongue is white thick coated still. Ice cream is a bitch. None for 25 days, why won't the tongue clear this time? I can guess I need more oil to cause Candida to drown and slip off. I'm going to say I need a ton of probiotics, that would clear candida out also, or more fasting on nothing to clear this junk out. Oxygen does it also but people have to inject it right into the blood and takes a trained nurse.....I'll get the probiotics and increase my nitric oxide also, I heard garlic and vitamic C combo does that 200% up, whatever brings energy back. I have still 30 lbs to lose. I don't like the bed ridden part but that's the only way I ever lost weight was to stop eating.

[@dylanmatusek6477]

Theoretically a low inflammation diet should help?

[@ajm2872]

Fast.

[@kangwachisanga2764]

Such a helpful video. THank you so much! l love the way you described why obesity happens and why. Very well done

[@Saddamhussain-yo7mw]

Much informative... I love the way you teach

[@haniyeamjady1715]

Very good explanation

[@Priya_Dutta]

thanks for the great explanation & graphical representation!

[@Alilamedicalmedia]

You're very welcome!

[@jorgerivas7714]

His hi Alila medical Media! A video about cellular immunity would be amazing. More about infections would be amazing!!

[@jonhollis2447]

Obesity is not caused by earing too much fat. It's almost always caused by refined carbs, especially sugar. If I decrease or cut out refined carbs, I get lean, regardless of how much fat I eat. The amount of fat I eat is controlled by my hormones, and these tell me to stop eating when I'm full. This is how the body is meant to work. The human body goes to pieces on a low-fat diet high in refined carbs. If you don't believe me, look around, and you'll see all the fat people.

[@stevemarshall_uk]

Exactly, we evolved to primarily eating fats and meat, some plants and seasonal ONLY fruits/berries. The body and organs LOVE ketones Generally Sugar/carbs are inflammatory and nowadays are behind type2/1/Alzheimer’s(type3) diabetes Good fats are anti-inflammatory and cells are made of lipids(fats) and brain is mainly fats

[@MuhammadMubsharManzoor]

I love you this vedio thanks for teaching like this

[@aeshakamal2002]

thank you for making it simple

[@ФилипАтакер]

great video thank you so much

[@lizabraham3034]

Thank you so much and very much appreciate your work! This video explained it perfectly for me yet concisely in 5:39 mins.

[@ivanchu7121]

Great presentation. Strange you not getting more views and 👍

[@oreoqueen2254]

Thank you!!

[@aneevrian6557]

Thanks for the vedio! It was very helpful

[@lordscuti9671]

Good video there’s soo much I need to learn I heard all of this but I didn’t truly understand all of this

[@humananatomythoraxabdomenp827]

Thanks a lot your video was very informative

[@raynaboyarsky4591]

love you and your videos!

[@kiranraj.s.p3903]

Good explanation

[@StuffMadeOnDreams]

Hunger is per se not a sign one is going to fall stone dead in a matter of seconds. We should experience hunger as a healthy alert mechanism but not take it as an indication of starting eating straight away. Many animals are hungry and continue their search for food. As we were on the savannah without fridges and fast-food restaurants for millions of years, hunger is only a mechanism that helped us to be alert and to look for food before is too late. However, we are not on the savannah any more and food is available at the snap of fingers, eating straight away when we are hungry is a bad habit we have developed culturally over the last 12 thousand years. Always think what you are going to do after eating. If you are going to sleep, avoid eating. After all, after 10 pm your body should stop being hungry because we are diurnal animals and the body interprets the lack of natural light as an indication of going to sleep. If you plan to do exercise or phyical activities, eat accordingly. Eat a lot in the morning and nothing at night. Drink water to saciate the stomach without calories and to burn calories.

[@stevemarshall_uk]

All Good, BUT the emphasis/speak moves from high-fat-high-carb to high-fat(only), omitting the high-fat-high-carb emphasis So does need edited.

[@dogstorme9333]

Eating the wrong foods will confuse the brain into thinking it’s starving, therefore other parts of the body will follow suit. Eating the right foods will keep your insulin levels at a constant level and won’t drop like it does with high amounts of glucose or pure carb heavy foods. Eating protein and healthy fats are what we are designed to eat, not processed food, change it and you’ll be fine

[@sanjaisrao484]

Thankyou very much

[@chelsea9013]

What are the major physiological consequences of removing ghrelin-producing cells through metabolic surgery?

[@GoingGreenMom]

So what does it mean if you don't feel hungry but are still insulin resistant and overweight? Both options given seem to say that overweight people should be hungry all the time, and I have to set alarms to remember to eat.

[@bluehairkim1]

Is there a link for this type of education explanation for other types of eating disorders such as anorexia? Food and version? Aphid?

[@ouivalerie]

There's just a lot of people that desperately want to stay super skinny.

[@tauane.menezes]

What an amazing video! Thank you so much for this content.

[@TheAmmarKeylani]

Excellent video. Subscribed!

[@NarayanaSnorescape]

Can I add this to my blog with courtesy mention of your brand pls.

[@Alilamedicalmedia]

Please see the "About" tab on our channel page for information.

[@MohammadBetar]

Very helpful 🌹🌹🌹

[@Zeverinsen]

Well, being affected by obesity during infancy really does explain *a lot* and it's talked about surprisingly little.

[@yuyanzhu5118]

at 3'28'' saying "obesity is most commonly associated with low leptin" is wrong! obesity usually has high leptin level

[@Alilamedicalmedia]

It said "leptin activities" not leptin levels - you can have high leptin levels but are resistant to it, just like some diabetics can have high insulin levels but insensitive to insulin.

[@asenanar-sw4tn]

Im confused, leptin is released from fat tissue or because of fat tissue? If yes, why obese patients have low leptin ?

[@Alilamedicalmedia]

Yes, and your confusion is about cause-effect relationship. Normally, high fat leads to more leptin which acts to reduce hunger => less fat - a typical negative feedback mechanism. If this works, the person would NOT become obese. The reason why someone becomes obese is because this mechanism does NOT function normally - the person always has low leptin, which makes them hungry all the time, they eat all the time and become obese. Low leptin leads to obesity (not the other way around).

[@asenanar-sw4tn]

@@Alilamedicalmedia but after what this mechanism stop working? Chronical carbonhydrates?

[@Alilamedicalmedia]

There can be many reasons, including genetic.

[@akramkarim3780]

what about the role of Arcuate nucleus in sexual behavior ?

[@universeusa]

Thanks! 3:39

[@safiamohamed6462]

Thanks :)

[@ajammeelkhan786]

Hii

[@xxnajdxxful]

🤩 perfect

[@_ShafaAzizah]

what is NA and VTA

[@Alilamedicalmedia]

Nucleus Accumbens and Ventral Tegmental Area

[@jinagibson6818]

I've not read infant formula, supplements since my own were born. We followed WIC and peds suggestions with input. I've always known they need be better. Mother's milk does lack. No body is perfect.

[@frinoffrobis]

increase leptin, ok how?

[@ahmedahm1]

3:17

[@janitortech3264]

1 dislike ? Why ?

[@pussylumpessru]

cus u a janitor

[@so505kean5]

Most likely an accident. 👍🏻

[@floramuradyan8184]

Hi, I need news about cellular immunity, too It will be perfect. Thanks

[@b-manz]

This completely false in the sense that energy in energy out is a calculation the body uses.

[@CHARANTHARAK-831]

Mdks from