This is a great simplified version what these 2 very important, very complicated hormones do. Good job.
@Paul-hl5ls2 жыл бұрын
How would someone test for leptin resistance. How is that treated?
@Simbwaful2 жыл бұрын
Thank you not only for drawing this topic so clearly and breaking everything down, but also for the great learning tipps!
@loricalass40682 жыл бұрын
I can’t speak for anyone else’s experiences. Everyone’s body is different. But I saw a difference with LEPTIN overnight. I was less hungry. At the same time I was not tired. I think this will help me lose my final 12 pounds. And I think it will help with the food bill.
@step_zero3 жыл бұрын
Hey guys. I misspelled APPETITE.
@carmst423 жыл бұрын
Thank you!!! I was struggling with Leptin but this finally made it click
@step_zero3 жыл бұрын
happy to help
@lanadecker88005 жыл бұрын
Great video!!! Super informative and very clear. Please, create more of those :)
@KoiRun50 Жыл бұрын
With leptin think of ‘lips.’ Imagine closing your lips when you are full and don’t want anymore food. Just another way to remember what leptins do.
@Kimtomaska2 ай бұрын
Great memory tools for remembering which hormone does what and what area of the hypothalamus 👍🏽
@j4ta6802 жыл бұрын
Great pneumonics, easy to understand, thank you!
@Angela-cd9bj2 жыл бұрын
Excellent explanation of Leptin & Ghrelin hormones. Thanks 😊
@syoofmadkhaneh65702 жыл бұрын
greatvideo.. thank you so much
@saudalamoudi82 жыл бұрын
Great video
@gamegirl181 Жыл бұрын
very helpful video, especially regarding the mnemonic devices provided. but what i find really funny is that people in the medical field are often way too used to looking at things from the anatomical point of view so left becomes right and vice versa. i noticed it when he was presenting those two medical cases at the end of the video. this often happens to me too so it's nice to see i'm not the only one
@CanIChangeThisWorld-lu1xl2 ай бұрын
Very helpful and well done. Thank you!
@123sanoon5 жыл бұрын
Very good explained. Thanks.
@hanknelson32315 жыл бұрын
How to master these hormones by getting the benefits of both without the downside? Ghrelin produces HGH and IGF-1 which burns fat, but makes you extremely hungry and lethargic. Leptin is only stimulated by carbohydrates that make fat.
@makeupkiddo4 жыл бұрын
Great video thanks
@AnaSantos-ge7yz Жыл бұрын
excellent video and ways to remember complicated stuff! thank you :)
@aiimscapsule29546 жыл бұрын
Perfect video...
@step_zero6 жыл бұрын
thanks !!
@thisisgerome63756 жыл бұрын
Very good lesson, thank you!
@TarigOmerEducational8 ай бұрын
mnemonics were creative
@loricalass40682 жыл бұрын
As soon as I started taking leptin I noticed a decrease in my appetite. I think it helped me lose the rest of the pounds I needed to lose so that I could be at my recommended weight.
@myyoutubechannel3161 Жыл бұрын
Taking leptin ? What do you mean I didn't know you can ..
@Lauren-vd4qe9 ай бұрын
no leptin supplement that i have found. explain!
@loricalass40689 ай бұрын
@@Lauren-vd4qe you’ll just have to try it and see for yourself how it works for you personally.
@annav22958 ай бұрын
@@Lauren-vd4qeit’s a bot probably
@Lauren-vd4qe8 ай бұрын
well his concept is correct but i think hes mistaking that zinc gluconate is the item he took as it does indeed cause leptin to activate and definitely increases saity levels, reducing appetite. @@annav2295
@JaeJay04 жыл бұрын
Thank you for this
@Mengjoanne3 жыл бұрын
Is there a correlation between glucagon with lipolysis and leptin secretion?
@AuggieX16 жыл бұрын
Excellent video.... thank you!!
@abrorakhmedov73892 жыл бұрын
thank you for your great video,
@Nocomment13 жыл бұрын
What happens to Ghrelin on long fasts? When I fast for 5 days my hunger completely goes away around the 36-48hrs in. What's inhibiting Ghrelin in that case.
@PrettyXXEmpty3 жыл бұрын
Have you found the answer? I'm also having the same problem
@Owsse3 жыл бұрын
i would assume it's ketogenic adaptation, when your blood sugar is stable, insulin is low and ketones have replaced the majority of your energy demands then hunger can be reduced/diminished until your fat stores and trash amino acids are starting to become scarcer. If you think about it, once you tap into your fat storage, your body enters a place where there's like 30-100 days of food in calories depending on if you are 10% or 30% bodyfat, why would it be hungry?
@step_zero3 жыл бұрын
ketogenic diets have a large host of benefits as long as they are nutritionally well rounded and fasting is a great tool for hormonal balance + weight loss.
@CarnivoreNana2 жыл бұрын
I try to do keto and have been successful but HUNGRY ALL THE TIME!! I have fasted from Friday dinner to Sunday lunch. Very much a struggle. Im hungry all the time and mentally have to say to myself...u ate already and it was enough. My stomach pains are many times worse than before I eat. Advise? Ive asked the dr but they dont know.
@itscoldouthere8971 Жыл бұрын
@@CarnivoreNana I have this same problem! Make sure you're drinking enough water and incorporating an adequate amount of protein!
@charlestackett71374 жыл бұрын
Thanks for the mnemonics.
@lildrEaming5 жыл бұрын
Thank you! Wonderful video!!
@almaha90022 жыл бұрын
Amazing explanation!! Thank you ❤
@bytemebiz5 жыл бұрын
great vid
@zeyneppp81982 жыл бұрын
Thank you so much
@manjushalahri388 Жыл бұрын
Thank you
@Lauren-vd4qe9 ай бұрын
HINT: and HOW do you turn leptin ON in your body? take ZINC! i find that zinc gluconate is the best way to do this; I cut the zinc gluc 50mg pills in half (use a pill splitter its great) in a bunch and put them in little container, take 1 half pill in morning with food and 1 half pill with dinner. eat your MAIN meal (dinner type meal) at noon time, then at 5/6 pm have a very light meal, ie mostly veggies, bit of starch, bit of meat, about 1/4 of what u wd normally have. no sugar, coffee, alcohol they destroy your program and your body. works great.
@ricardodelacruz2316 жыл бұрын
Great!!!!
@onecompass72903 жыл бұрын
I have this malady. I am never 'hungry'. It's not about 'appetite'. These words are misleading. I wish they could be replaced with 'metabolic drive and causation' or something of the sort. What I experience is a constant subconscious drive/urge to eat that is driven by the imbalance. Behavior should be replaced with the word 'outcome' etc. Let's frame it correctly and take out any hint at individual person driven decision making. If your body tells you that you are cold you put on a sweater, if your body tells you that your are 'starving' you eat.
@rubyjain5585 Жыл бұрын
Thanks a lot. A great help.
@giddal.2752 жыл бұрын
Great video!! Thank you!😁
@UuuuHjbbhnn23 сағат бұрын
What if your leptin is too low
@Recon777x2 жыл бұрын
So if fat produces leptin, why don't we feel satisfied if we're fat? What is the mechanism that prevents fat from suppressing appetite? Because quite obviously, fat people still get ravenous, making the problem worse.
@step_zero2 жыл бұрын
Obesity is a complex disease and likely the hormone response baseline is adjusted in obese people so hormones do not function as they should
@elijahgavin67069 ай бұрын
Doesn’t obesity often correlate with insulin resistance, and insulin stimulates leptin?
@myyoutubechannel3161 Жыл бұрын
What If the grehlin hormones in the stomach are not being produced or simply put, you have no appetite ? Or you have No desire to eat
@user-zq2bq8wl4b3 ай бұрын
Thanks ❤
@alphatomy86132 жыл бұрын
thank you so much. i really apreiciate your effortd.
@Dr.DaveStrength3 жыл бұрын
Thanks so much!
@fernandacerqueira20205 жыл бұрын
Great video! Thanks!
@Y29314 Жыл бұрын
are you mr morj one piece youtuber?
@flourishomotola53063 жыл бұрын
You're a GREAT TEACHER bro.
@step_zero3 жыл бұрын
thanks bro
@FitnessTechAk3 жыл бұрын
Ghrelin for Growth :)
@CarnivoreNana2 жыл бұрын
I feel like this all the time. I feel hungry even if I eat, and eat propertly and enough. Many times after I eat its worse than hunger pangs. Dont know what to do.
@abdalrahmanayman70694 жыл бұрын
thnx sir. ☺️
@ginoasci28762 жыл бұрын
can either of these two hormones cause burning in the upper abdominal area when it’s time to eat? three or hour hours after a meal, my stomach doesn’t growl, it burns.
@elijahgavin67069 ай бұрын
Get tested for H. Pylori
@ginoasci28769 ай бұрын
@@elijahgavin6706 : did that. Thank you.
@anitajulaniya19592 жыл бұрын
How to regulate leptin and reduce the appetite consciously?
@francescakray2333 жыл бұрын
Thank you ... 🙂
@francescakray2333 жыл бұрын
Thanks.
@euma52854 жыл бұрын
Why is it sounding like I need to have brain surgery to finally lose weight?🤕
@deezeed28174 жыл бұрын
I fixed it through fasting. People with obesity aren't Leptin sensitive. I would do 48 fasts and then eat one meal a day and gradually as my weight came down i found i couldn't eat the same amount as before. This is why obese people cannot lose weight. The Leptin doesn't work properly because obesity is like a disease that screws all your hormones up. Cutting out sugar also helps. So much of our health problems come from too much sugar.
@Itzbrady_4 жыл бұрын
@@deezeed2817 I agree. Rolling 48's an keepin the carbs low upon refeed to work pretty amazing :D
@gardensofthegods3 жыл бұрын
@@deezeed2817 you might want to look into something that is dirt cheap that has been used for thousands of years and you don't need a prescription ... do you know about methi powder ... it is fenugreek seeds . And India and that part of the world they have used it for thousands of years as a treatment for diabetes and it balances the hormones for both men and women . The only problem is it does taste very bitter . You usually can get it at almost any Indian Grocers ... just mix with water or juice and drink it
@ninojejelava6 жыл бұрын
what about the brainstem and hunger regulation
@step_zero5 жыл бұрын
by brain-stem you are referring to hypothalamus
@portiasT1234 жыл бұрын
How do I increase ghrelin
@310sbell2 жыл бұрын
This se ms like me a little. I eat way more than I need to and always want to eat more. I don't need a bunch of sugars I stick with healthy whole foods meat vegetables that are fresh. No boxed meals nothing like that but I can finish a meal be hurting full and then walk in the other room and want to grab something else to eat. Anybody know a way to stop that?
@panav7723 Жыл бұрын
anyone the citation for the mouse model experiment?
@nixland4 жыл бұрын
So how can you explain about lots of my friends that are lean till age 30 and then get obese and fat after that?
@kneetotheface4 жыл бұрын
nixland ur friends are getting older and past their prime in regards to their metabolism but they still input calories in a ratio that causes weight gain. time is a sonofabitch.
@callacartaxi37414 жыл бұрын
many reasons, skeletal muscle decrease, due to lack of use, NAFL, excess carb consumption, excess omega 6 FFA and carb consumption combined with lack of sleep, lack of rest, excess fructose consumption. poor lifestyle habits take tears to manifest in obesity and metabolic derangement
@chrisdion32603 жыл бұрын
There's a good chance they've been having too much sugar in carbs up until that point and they have finally hit a Tipping Point on insulin resistance which has now made it so that they are not only resistant to insulin but also resistant to the effect of leptin. do some research on insulin resistance here on KZbin and you'll find some amazing stuff.
@TerriYoung-n3n5 ай бұрын
I can't subscribe right now but I'm interested because I have eye problems and I'm going through some women lead things so please send me your info
@trustenbaker87663 жыл бұрын
Well why would I be hungry with bloating? I mean I just ate like an hour ago. I'm scared to eat anymore because I found myself at the ER this morning with painful distension. They did cat scan and other stuff, blood work and all that stuff. Far as they can tell nothing is really wrong. I'm seeing a GI on Tuesday, but........well I was scared to eat what I did today earlier. But I feel hungry as hell. I'm a pretty slim guy not fat or anything. Well anyways you may not obviously know these answers. I'm hungry but scared to really eat again.
@step_zero3 жыл бұрын
If I was you I would eat something small and see how I feel after. Staying well-hydrated can also help. Hope you are ok and able to see your GI soon.
@jonnyfranco73 жыл бұрын
this makes sense because when i started fasting is when i started yoyoing
@abrorakhmedov73892 жыл бұрын
i have a daughter she had -Enterocolitis problems since 1 year old she is 4 now 😢 so we had to do diet after doing diet she is ok now not vomiting or bad breath but shes feels hungry all the time do you think this is because she is eating fat free foods diet food, as long as i know fat will help to produce laptin, i have taken to doctors, unfortunately, they could not give any decent answer so im doing my own reasearch, i'm thinking may be to give litlle lamb fat after meal so body can get laptin produced ? if anyone can help with this health issue i would be happy as a father. also we have gave blood for vitamin analysys doctrs said it's in the norm level.
@step_zero2 жыл бұрын
You can try an elimination diet intriducing foods one by one and seeing what she is sensitive too. Hormone levels also change with age so this may improve with time.Foods higher in protein and fats and fiber are more filling and can produce satiety if that is what you are looking for. It is good you are doing your own research and getting informed but please double check information you get form online forums.
@danielpincus2216 жыл бұрын
How does insulin interfere with leptin reaching the brain?
@step_zero5 жыл бұрын
not sure sorry
@George-bq9wv4 жыл бұрын
it's synergistic effect , by inhibiting the AGRP/NPY leptin receptor , and stimulate the POMC and CART leptin receptors so we decrease food intake. you can also add CCK along with them.
@lulurickert4 жыл бұрын
“Appetite”!
@patcomly98863 жыл бұрын
Spelling matters. Two p's in appetite--maybe picayune, but details are important to me for credibility. Good information, anyway.
@step_zero3 жыл бұрын
You're totally right. My mistake. Hopefully, it was informative even with the error
@flyrehash51243 жыл бұрын
why is pp so important to you
@torptjejen4 жыл бұрын
QUESTION: I never feel hungry and if I eat I never feel full no matter how much I eat. Any idea how to get these to work properly? Thanks! 🙏
@step_zero4 жыл бұрын
good protein and fiber intake , lower glycemic foods and good hydration are just some general advice. Best thing would be to see a dietitian.
@CarnivoreNana2 жыл бұрын
Dietians...smh. They tell me things my body just doesnt deal well with. I just gain weight cause they say eat these carbs.
@madams989 Жыл бұрын
@@CarnivoreNana ultimately if you're in a deficit you will lose body fat. It may just be more difficult for you to keep your calorie intake down. But it'll work if you can find a way.
@jannatjan9370 Жыл бұрын
I want to increase garline harmone plzz help
@TheRachelDJ5 жыл бұрын
What are your sources for this information? Any specific journal articles you used for these examples?
@step_zero5 жыл бұрын
Im just basically reciting stuff i learned in med school no sources sorry
@George-bq9wv4 жыл бұрын
everything was correct , you can check guyton physio.
@znrv33453 жыл бұрын
Hay I would like if you could replay to me. I always say that I like the human body and the way it’s operates but this this is just depressing this is literally say that some people are cursed to have low self esteem and the worst part is people judge and who can blame them they don’t really understand the difficulty of eating and never felling full or not eating and always feel full... can you please tell me if science is working to put an end to this curse?
@step_zero3 жыл бұрын
there are medications and substances that increase and decrease appetite. For example, Caffeine decreases hunger and THC increases it.
@Rebecca-vr3dr3 жыл бұрын
What are normal leptin levels
@step_zero3 жыл бұрын
Serum leptin (ng/mL): 9. 7 ± 4. 7
@ladyfafa37703 жыл бұрын
How to activate my ghrelin
@gardensofthegods3 жыл бұрын
Well if you think the problem is coming from your hormones not being balanced ( because that can cause problems ) I would suggest you look into methi powder ... do you know about that it's fenugreek seeds . It balances the hormones for both men and women alike and it has been used for thousands of years as a treatment for diabetes . You can buy it very cheaply at almost any Indian Grocers but the stuff does taste bitter
@ethanwarchol16773 жыл бұрын
You sound just like Kharma Medic
@danielpincus221 Жыл бұрын
Friendly observation: Suh-TIE-yety.
@chengfusaechao72435 жыл бұрын
As for me..the reasons I Eat is because I am so.... Sad😥depressed.lonely. Mad.Anxious.bored and Did I mention.. ALONE😭 And..NO..I'm not FAT..OR maybe I'm HUNGRY all the time is because i Have PARASITES inside of me & eating all the foods I ate..because i am Always eating & snacking But not fat.WTF?!!🤔🙄
@step_zero5 жыл бұрын
Go to your doctor. They will likely test your thyroid, and do a blood test. Getting regular checkups is important. As for your mental health your best bet is joining some sort of team or club with people that have similar interests, oh and exercise helps correct hormonal balance which will help you feel better. Hope this helps.
@gardensofthegods3 жыл бұрын
I'm just curious if you ever found out why you are so hungry all the time ... did you get your health checked out ?