Leptin Resistance | Symptoms, Causes, Treatment, & Reversal

[@drmorgannolte]

Join the waitlist for our online course, community, and coaching program, Zivli, that helps you lose weight sustainably and lower insulin resistance at www.zivli.com/join.

[@Blossom-73]

When we eat, insulin makes the fat cells open up and eat too and then they secrete the hormone leptin to go to the brain. That's how the brain knows that we eat. The brain reads leptin and sends it back to the fat cells to tell them to open up to release energy. When fat cells read the order from leptin they produce Adiponectin the key hormone that makes the fat cells to open up and release energy. But if the brain doesn't read leptin (propably genetics), the fat cells don't open so when they eat again, they will open again to fill up again, swell, become inflamed and then retain fluids to extinguish the inflammation. The water mixes with the fat and it is also becomes fat. So you gain weight by drinking water too. So the brain doensn't know that you eat. Then the brain thinks that you are starving so your body gets on starvation mode meaning that the brain make you storage everything you eat, zero metabolism and gets your ghrelin hormone higher to make you feel hungry to eat more. Leptin is responsible for the creation of the bones since birth. If you are born with high levels of leptin (genetics) then your leptin will make you have a heavy bone stracture to endure the future high obesity weight. Ghrelin on the other side has a very strange side effect. High levels of Ghrellin create a very strong muscle mass from the early age of 5 years old affecting and lowering insulin levels. So the best way to lose weight is to bypass the process where the brain doesn't read leptin and this is done with an adiponectin pill so the fat cells can release energy without creating more inflammation in the fat cell, no more fluid retention no more extra fat inside the fat cell. BUT the World Health Organization refuses to license a pill of adiponectin and leaves the obese to suffer.

[@queenlynails]

It’s so good to hear someone explaining this and that it’s so much more than willpower!! It makes me feel so much less alone

[@drmorgannolte]

So glad to hear that, thanks for the feedback!

[@bearbear4030]

I was a 118 pounds…my physician put me on a medication and I gained 100 pounds. Another doctor took me off it immediately and I lost 50 pounds immediately! Now, I’m all about intermittent fasting and OMAD to get this off me! I hate IT!

[@lillil6490]

Can I ask which medication?

[@utopiadweller]

2:18 leptin insulin. 5:30 weight loss. 7:16 leptin resistance

[@drmorgannolte]

Thanks for adding these timestamps. I add them to newer videos in their descriptions FYI.

[@ewaoconnor]

Thank you very much for sharing this without charge 🥰 I have learned more about leptin and insulin interactions

[@drmorgannolte]

Thank you for watching and for your positive feedback! We're glad you found the video informative. Be sure to subscribe to this channel to guide you more on your health journey: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@ericdanieltorres1918]

I love the way you teach. Your lecture pace is perfect for me to learn completely without having to listen to it again. Simply wonderful! I’m a 43 year old male; I hope this can work for me as well and not just for my wife. Either way Thank You Dr.

[@drmorgannolte]

This is wonderful. I am glad to be of help. Have you downloaded my Ultimate Food Guide? It explains which foods are healthy and not related to how they impact blood sugar and insulin. I think you’d find it helpful. You can download that at www.zivli.com/ultimatefoodguide. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@hollywarehouse4606]

Good morning Dr.! I’m a new subscriber. Thank you, for this video I have been on Prednisone for 40 years for Crohn’s. Started @ 110lbs… Gained 80lbs during Pandemic on my 5’1 frame. Lost 50lbs so far but I’ve been STUCK for months. I appreciate the information, and 🙏🏽 Everyone STAYS well!

[@drmorgannolte]

Hi Holly! Thanks for subscribing. Glad you enjoyed this video and we have lots of great content coming on both weight loss strategy and mindset this year so stay tuned!

[@plarkin6433]

@Holly Warehouse hi, have you seen Peter Osborne DC YT? I think he will help you God bless You

[@suzu363]

Dr. Morgan, I am so very exited. I just came across your Chanel here on youtube and this is the very first video I watched. I can not tell you how exited I am right now to finally see someone, a doctor to focus on women and their issues relating to menopause!!!!! Thank you , thank you! I absolutely loved this video, and your way of clear easy to understand science based explanation. Thank you, and I will now start consuming more of your content in hopes of learning ways to manage this miserable perimanopause weight gain.

[@drmorgannolte]

This is definitely a good news! I am also glad too. Thanks so much for watching and leaving a positive comment, I hope you found this video valuable. Also, kindly subscribe to my channel to guide you more on your health journey: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@RachelSmets]

This is so interesting. I've heard about leptin but you broke it down SO well! Thank you

[@drmorgannolte]

Good! I'm glad to hear you followed along there was a lot to cover about leptin! You are so welcome.

[@jk3266]

In video of 20 minutes, you explained so many things.This is The Best video I saw on KZbin.Do you write blogs ?

[@drmorgannolte]

Yes I do! You can check them here: www.weightlossforhealth.com/blog

[@YesToTech]

This is super helpful Dr. Morgan! Absolutely adored your advice!! :)

[@drmorgannolte]

Thank you!

[@ErikYuzwa]

thanks for this video! Been on keto and an 18:6 IF for over a year, and at first my fat was melting off, but for the past 2 months it's been creeping back up with no change in my macros. It's been frustrating, and I've only recently come across this topic of leptin resistance so I'm curious if that's what my body is doing against me.

[@drmorgannolte]

Hey I can help you out on this. I offer a one-time Lifestyle Audit. This is a 60-minute Zoom call where we look at your past medical history, goals, and lifestyle to create an optimized plan to help you reach your goals. For more info on that, you can email [e-mail]. Or you may also try my 30-minute discovery call to explore more. calendly.com/drmorgannolte/discoverycall. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@pb8253]

Hi great and easy to understand

[@drmorgannolte]

Thank you! Glad you enjoyed it and thanks for watching :)

[@Adrienneten]

OMG - I feel so defeated already - I have been IF for years and now find out here that I am at least three medications that raise my blood sugar

[@drmorgannolte]

It sounds like you'd get a lot out of our free upcoming Blood Sugar Boot Camp March 13-15. You can register for free here: www.zivli.com/bootcamp?el=YT. Thank you!

[@LeadersHQ-1]

wow... a great explanation.... I didn't realize before that fat was a separate hormone organ.... that helps me plan what to do... thanks

[@drmorgannolte]

Thanks for watching! We hope you found the video informative. Be sure to subscribe to our channel for more health tips! ❤️

[@lorblacor]

Such an informative video! Thank you!

[@drmorgannolte]

You're so welcome, Lorraine! That was a complicated topic so I'm glad you enjoyed it :)

[@jbitakis]

I did 16/8 IM for 2 months. It didn't help me lose weight and I was starving during the 16 hrs.

[@YSuniQu-ss6wp]

Thank You "You shall know the truth and the truth shall set you free!

[@Gb_da_profit]

What would be the opposite of leptin resistance?for example the lack of appetite as well as difficulty gaining weight despite caloric surplus?

[@savitham1560]

Thanks for info.. 🙏🏼

[@drmorgannolte]

Thanks for watching and commenting, we hope you found this video helpful! Be sure to subscribe to this channel to guide you more on your health journey: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@clippers4me]

I'm male prediabetic and just started walking everyday for 30 minutes. After my walk I get hungry so I eat a fairly good amount of food that includes protein and veggies. 10 minutes after eating my stomach starts growling and feeling hungry, I'm so frustrated. So I then eat more chicken to see if maybe I didn't eat enough. After same thing. My stomach is still growling! This is so god dam frustrating! I know dam well I ate enough food. I wonder if what I am experiencing is Leptin.

[@drmorgannolte]

The first things I would try are to drink more water, increase the veggie portions, and add healthy fat. Any change takes time and consistency so hang in there!

[@julieellis6793]

If you're eating chicken breast, you're not getting enough fat, so you get hungry much sooner. Chicken doesn't hold me very long at all. I eat mostly beef or bacon, which satiates me for much longer.

[@dangallagher8034]

This channel is an incredible resource. Thank you very much Dr. Nolte.

[@drmorgannolte]

Thank you for the kind words! Much work and research goes into these videos so I'm glad you appreciate them :)

[@Magnulus76]

There's some mechanistic explanations that high levels of saturated fat and systemic inflammation might actually alter pathways in the hypothalamus that interact with leptin, causing leptin resistance.

[@klleigh72]

Great video keep it up!

[@drmorgannolte]

Thanks, will do! Please don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@karenhogan731]

So helpful thank you!

[@drmorgannolte]

Glad it was helpful! Thanks so much for watching and leaving a positive comment, I hope you found this video valuable. You might want to check on this video in relation to this topic: kzbin.info/www/bejne/gmjWqWZoocSkopY . Also, kindly subscribe to my channel to guide you more on your health journey: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@TheRachag]

Good content

[@drmorgannolte]

Have you downloaded my free masterclass that teaches you how to lower insulin resistance and inflammation? I think it would really help you. You can download that at www.weightlossforhealth.com/masterclass. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@kentofmississippi]

After reading scientific literature I have deduced leptin resistance is underlying my issues. most likely brought about by a poor diet in childhood and extreme sustained stress.

[@drmorgannolte]

Glad you're finding answers, best of luck!

[@deepdiver849]

how to fix the skinny fat issue? I dont want to loose weight... i just want to have a toned body, and even gain weight, but turn the skinny fat to muscles. unfortunately I had a bulging disc issue, so cannot do many exercises.

[@drmorgannolte]

I offer a one-time Lifestyle Audit. This is a 60-minute Zoom call where we look at your past medical history, goals, and lifestyle to create an optimized plan to help you reach your goals. For more info on that, you can email [e-mail]. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@brad349miller]

I've watched this before?! I have no memory of this place.

[@dr.dansullivan]

Very thorough, thank you for sharing!

[@drmorgannolte]

Glad it was helpful!

[@Monhaven98]

Thank you

[@NickMarshallMusic]

Check out Jack Kruse's work on Leptin. It's mainly affected by Light and Cold!

[@drmorgannolte]

Thanks for sharing!

[@WendyTalkRadio]

Thank you for this- truly! Generic of lexepro (ecitalopram) since 2006. Weight doesnt drop...unreal.

[@MrDcarrion]

Que Bella! Thank you Doc

[@drmorgannolte]

You are so welcome! Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@TheKrusso]

She is not a medical doctor. She has a doctorate in physical therapy.

[@humerashahid22]

Every time feel hungry How can reduce the appetite of food Please help I cannot loose wright

[@tiredofallthis7716]

Lines up with everything thing I’ve learned so far

[@drmorgannolte]

That is great! Have you downloaded my free masterclass that teaches you how to lower insulin resistance and inflammation? I think it would really help you. You can download that at www.zivli.com/masterclass. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@magentamagenta1274]

I have very high leptin I have had Graves’ disease and now Hashimoto also fibromyalgia. The increase in leptin which doesn’t make me hungry as I fast and eat two small meals a day. I have lost 10kg but been stuck at the same weight for the past six months. I am a vegan eat low carbs, nuts and seeds mostly a healthy meal of protein, low carb veg around 1200 -1500 calories a day. I exercise everyday and have increased HIIT and walking. It’s very frustrating any suggestions will be helpful.

[@drmorgannolte]

I can definitely help you with that. I offer a one-time Lifestyle Audit. This is a 60-minute Zoom call where we look at your past medical history, goals, and lifestyle to create an optimized plan to help you reach your goals. For more info on that, you can email [e-mail]. Or you may also try my 30-minute discovery call to explore more. calendly.com/drmorgannolte/discoverycall. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@magentamagenta1274]

I have subscribed and listened to a few of your you tube video’s. I will be in touch. Thank you for getting back to me :)

[@mrym80]

Your body probably thinks it’s in starvation mode. Little food, lots of labor, not enough nutrition. Check out Dr Saladino 😁

[@sammielovessophie9519]

Thank you!!!

[@drmorgannolte]

Thanks so much for watching and leaving a positive comment, I hope you found this video valuable. You might want to check on this video in relation to this topic: kzbin.info/www/bejne/iKStha1rbK2dm6c . Also, kindly subscribe to my channel to guide you more on your health journey: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@sarawallacejoines6170]

I had my blood work done. I have high levels of leptin, but glucose and A1C were all normal. Does leptin resistance not always go hand in hand with insulin resistance?

[@drmorgannolte]

We can discuss this one further. I offer a one-time Lifestyle Audit. This is a 60-minute Zoom call where we look at your past medical history, goals, and lifestyle to create an optimized plan to help you reach your goals. For more info on that, you can email [e-mail]. Or you may also try my 30-minute discovery call to explore more. calendly.com/drmorgannolte/discoverycall. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@mrym80]

I heard that leptin resistance precedes insulin resistance.

[@LesleyRabie]

So you mentioned hormone therapy. Bioidentical hormones fall into this category?

[@TheMelodicMess]

My doctor said I can’t have my leptin levels checked at all. I believe that this is my underlying issue

[@drmorgannolte]

Here's one option I found online that your physician could use: www.labcorp.com/tests/146712/leptin-serum-or-plasma

[@TheMelodicMess]

@@drmorgannolte thank you so much!

[@majorerskineCH47]

Wow this is good! Thanks im a heath coach primarily focused on men…do you have an affiliate program that I can send you female customers…particularly perimenopause or menopausal.

[@cindybledsoe2423]

Thank you.

[@drmorgannolte]

You're welcome! Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@mikemoore2096]

Hi Dr Morgan! I have been learning about leptin. Was wondering if I can share something with you?

[@drmorgannolte]

Hi, you may try my 30-minute discovery call to explore more. calendly.com/drmorgannolte/discoverycall. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@_9563_]

I've done all this and still can't stop gaining! Where does circadian rhythm come into this? Thyroid? Thanks

[@cmclingan]

kzbin.info/www/bejne/h2baq2ZpmbyihK8

[@PouraniiEskandari-cq5jm]

I am always shaking and hungry so I can’t do fasting and low blood pressure as well i need help as even being on ozempic is not helping me 😢

[@karenmaupin6955]

Does this help women also in menopause?

[@cherylpaniccia4920]

Hi Dr. Nolte. I tried the link to the class and although the speaker on the video showed on and playing there was no sound. Thank you.

[@drmorgannolte]

That's just a little preview of the video. You'll need to enter your name and email to get the masterclass delivered to your inbox. Here's the link again: www.weightlossforhealth.com/masterclass

[@annfail-smith8500]

Hi...I take leptin...because I don't have it...I have lipodystrophy....I am insulin resistant....does this mean I am leptin resistant....let me know...Annie xxxx

[@farfoor4ever]

stress and sleeping problems are my issues , how can I deal with this ? it is very difficult ):

[@drmorgannolte]

I'm really sorry to hear that you're dealing with stress and sleeping problems. It can indeed be challenging, but there are steps you can take to improve your situation. First and foremost, consider speaking to a healthcare professional or a therapist who can provide personalized guidance. Also, relaxation techniques such as deep breathing, meditation, or yoga might help alleviate stress. Creating a bedtime routine, avoiding screens before bed, and ensuring your sleep environment is comfortable and conducive to rest can improve your sleep quality. Remember, you're not alone in this journey, and seeking help is a sign of strength. Take care of yourself, and I hope you find the support and strategies you need to overcome these difficulties. You may check out this playlist on How to Improve Sleep: kzbin.info/aero/PL5_RBZm7ejTsazsl7GC8cF1BAiG0Qm5Ej Sending positive vibes your way! 🌟

[@MariaMLoBalsamo]

Hi does HRT raise insulin? estradiol and progesterone ?

[@drmorgannolte]

Good question. Usually for women in perimenopause or just postmenopausal, it actually helps with insulin levels for a couple reasons. Estrogen is an insulin sensitizing hormone in the right amounts. The second is that they can really help some women sleep better, and better sleep reduces cortisol which lowers glucose and insulin.

[@MariaMLoBalsamo]

@@drmorgannolte appreciate you responding, thank you so much!

[@bellacrea2510]

I need serious help is there a way to call you? ? My situation is complicated. I'm desperate and no doctor has helped me.

[@drmorgannolte]

Hi sure, You can contact me. I offer a one-time Lifestyle Audit. This is a 60-minute Zoom call where we look at your past medical history, goals, and lifestyle to create an optimized plan to help you reach your goals. For more info on that, you can email [e-mail]. Or you may also try my 30-minute discovery call to explore more. calendly.com/drmorgannolte/discoverycall. Don’t forget to SUBSCRIBE to this channel for more health tips: kzbin.info/door/ByB8-b3CnXYuuWWyJ_vgzA

[@ferds6990]

@@drmorgannolte is this paid?

[@nellysmiles6041]

Is there a leptin diet?

[@drmorgannolte]

The best diet to reduce leptin is the same to reduce insulin because high levels of insulin is what is driving the high levels of leptin. Insulin is your fat creation and storage hormone. Leptin is a hormone secreted by your fat cells. The more insulin --> more fat created --> more leptin. My program covers nutrition in detail (www.weightlossforhealth.com/join) or Dr. Bikman's book Why We Get Sick, or Dr. Fung's book The Obesity Code are great resources, too. It's vital to remember that diet (what you eat) is only part of an overall low insulin lifestyle. It's important but there are other lifestyle areas to optimize, too.

[@nellysmiles6041]

@@drmorgannolte thank you

[@leeyost9917]

Hi

[@drmorgannolte]

Hi Lee, thanks for watching!

[@karenbole7130]

❤❤❤

[@livelearnandteach7402]

So, weight loss is a slow long-term project, not a quick fix.

[@haroldwagner4586]

So how many DKAs or Thyroid storms have you clinically treated,,,,,,, zero?,,,, thought so. Jokes on me

[@ferds6990]

I have done so many crash diets(probably 5) now I'm feeling extreme hunger and fatigue. Is this the cause of it? What do I do to fix it?

[@drmorgannolte]

Yes your nutrition is directly related to your hunger and energy levels. I would suggest you watch my KZbin videos on nutrition for ideas on how to properly fuel your body and stop crash diets.