GLP-1 Agonists: Wonder Drugs of the 21st Century?

The first drug in a class known as GLP-1 agonists was approved in 2005 to treat diabetes. GLP-1 drugs subsequently proved their mettle to treat obesity and prevent major cardiovascular events and will likely soon be available to treat sleep apnea as well. Looking ahead, their action on the brain is prompting research to gauge their value in curbing drug, alcohol, and nicotine cravings. But these seeming miracle drugs are costly, not always covered by insurance, and generally need to be taken forever. How do they work, what else might they do, and how do we ensure they are accessible to those who need them most?
Aspen Ideas: Health takes place on the Aspen Institute’s wondrous 40-acre campus in the Rocky Mountains from June 20-23, 2024. The three-day event, which has opened the renowned Aspen Ideas Festival since 2014, is where health’s biggest challenges meet its biggest thinkers. #AspenIdeasHealth #AspenIdeas
For more information about Aspen Ideas: Health, visit www.aspenideas.org/attend/health.

[@GoutamDAS-ls1wb]

If obesity involves the brain then it would have been a good idea to include a psychiatrist on board. GLP-1 analogs helped me get over compulsive snacking which in turn helped me keep my body weight in check.

[@lyndeeluu]

The best medication that I have ever taken.

[@cloakster]

35:58 Great discussion… but the next major GLP-1 drug to come out will actually be CagriSema (GLP-1/amylin dual-agonist), not Retatrutide. Would hope for that one by end of 2025, with Retatrutide following about a year later.

[@tommac5411]

What’s with the go go boots?

[@michaelclanton1152]

To Elimanate heart muscle mass loss I would think an echo cardiogram could be done on 1yr use patience.

[@sibelbaz5547]

I’m not sure, if I understood you right. You don‘t loose heart muscle mass. What you’re loosing is skeletal muscle mass. You’re build to stay alive a long time. First you burn your fat and later muscle to provide energy to the body. But if you wanted to say, that the heart muscle is “remodelling “ -and you get an better function with GLP 1, that ist right. Is the first time I’m commenting something in English, so I hope it’s not that confusing.

[@michaelclanton1152]

@sibelbaz5547 that is great info thank you

[@robincallawaywelch6004]

The question she asked at 9:52 wasn't answered. The 2 genius doctors didn't listen.