Cannabis and the Endocannabinoid System

How does cannabis work in the brain? In this video, we will discuss how cannabis products interact with the brains’ endocannabinoid system. The endocannabinoid system influences many brain functions including mood, memory, and stress. This system uses endogenous molecules called endocannabinoids to send messages to different parts of the brain. This system can be influenced by the presence of cannabinoids, which are found in the cannabis plant. Watch this video to learn more about how endocannabinoids and cannabinoids target different brain regions to alter behaviour and brain function.
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[@Cainoah]

I smoked 6 years straight from age 18-24 I have stopped smoking for two weeks bc of lung issues and have felt depression like I’ve never felt before. Nothing seems to be fun or entertaining to me I don’t feel like doing anything. I took anatomy this semester so all this makes sense. Gotta troop it out for another month for my brain to reset. Wish me luck

[@Benjamin-pn7gj]

Kinda freaking out bc I’m a year older than you same boat and same username. Still smoke but been contemplating for the lung issues

[@Benjamin-pn7gj]

Oh well not same username but my name on this google account is Benjamin Dover. Im high as shit but you get what I mean

[@austinjacobsonfr]

Don’t worry if even after a month you still feel the same, weed addiction is real and it’ll take time. u got this brother

[@jungwonmeeh9581]

If you smoked cannabis it is pretty normal to get abstinences because Longer use of cannabis can then affect your nervous system because the body produces its own terminal cannabinoids and when you somehow replace them with cannabidiol, the body stops producing it naturally and does not release as much dopamine as when you use cannabis, you can eventually feel more anxious and develop depression so just hang in there!

[@l4zrh4wk]

How are you feeling now bud?

[@johnnylongshlong3677]

Man I have MDD, GAD, and PTSD. Waking up is the worst, my body is in an uncontrollable state of panic immediately. I literally have two drops of CBD oil and I am at the gym, clear headed, relaxed, and getting on with it. Of course, I have worked on myself so I only use CBD to calm the central nervous system but it works unbelievably. I would also recommend microdosing psylocibin (mushrooms) for disassociation. I have my life back because of these plant based medicines that no pharmaceutical could achieve.

[@madness198648]

Everything you said I've also felt and experienced

[@johnnylongshlong3677]

@@madness198648 - sending you love and hopes for healing brother!!

[@gtavtheavengergunnerlegend3340]

same here. cannabis works more than anything prescribed

[@dasquid7216]

Yet weed and shrooms are still illegal in my state smh🤦🏻‍♂️

[@Gunnertrepleie]

Quit coffein , if you use it . And try gaba suplement . Cbd keeps your AEA levels up.

[@virginiawilson4615]

We are soo blessed to have cannabis… it saved my life..

[@giron822]

You're using an outside source to make yourself feel better. That's weakness.

[@Jblah]

🤡🤡 You dont use outside sources to make yourself feel better? Must be great being you. FYI Cannabis has helped many people be functionable again where pharmaceuticals failed@@giron822

[@austenhuddleston5703]

@@giron822in your opinion but then again no one asked. 😁 spread love not hate. Smoke a joint or enjoy an edible and learn to not judge what you do not understand.

[@CrazyChickenLady92]

​@@giron822ignorant. I hope you don't take antibiotics when you have an infection, using an outside source is weakness!

[@geministrial950]

​@@giron822 You sound like a pizza cutter. All edge, no point.

[@LS1Trainer]

Cannabis use has increased as time has went along. The rate at which psychosis happens has stayed the same. So no, cannabis doesn’t cause psychosis. If so the rate of psychosis would have increased along with the use of cannabis. Dr Lister Grinspoon who’s 30+ years of studies can cite this for you better than I can. You get the point though.

[@TheHannala2]

I think thats why he said it's implicated, not caused. There is evidence demonstrating a connection between THC and induced psychosis, but as with any drug the effects vary from person to person.

[@firstnameericlastnamecartm6306]

@@TheHannala2 cannabis is not a drug it's a organic herb plant that grows naturally

[@krazymanny2882]

Thank you brother, I had to stop the video cause CBD has no psycho active effects. I truly believe that before people speak on this sacred plant there needs to be real studies on our queen of plants. Krazy Kannabis!!

[@firstnameericlastnamecartm6306]

@@krazymanny2882 there has been study for about 92 years just racist laws have kept it illegal

[@blackpillfitness9136]

It might not be permanent psychosis. Only temporary. I know I experience a level of temporary psychosis when I smoke a lot of pot. Certain kinds of pot especially.

[@BennilocoLoves]

I use cannabis for my TBI.. no other '''medication" gave me any relief.. I now have my life back! Thank you for this video! 💚 Will be sharing..

[@rebeccaallen4555]

Contact the name above 👆I strongly recommend him he's trustworthy he ship to any location man he got all kinds of psychedelic product stuff's

[@user-pc3ek9nw9e]

You are not alone. I have a tbi as well and use weed for it.

[@kaynwells6936]

Same. TBI related ADHD and CTE annd PTSD. Only cannabis works on my brain. The stigma is still around so videos like this are great for education.

[@weedmafioso]

I understand people who say you can't get addicted but you can not physically but mentally but it is the same with everything we do televisions or video games can be addictive in almost a similar way as cannabis

[@sergiomissaglia6380]

Exactly. And also, did people forgot the power of the mind ? Someone that suffer from anxiety, depression and whatever can also have physical effects even if they are athletes. We should learn to use it with parsimony. Anyway, it's 100 times better than spending 4 hours on the phone that has probably the same amount of dopamine released

[@weedmafioso]

@@sergiomissaglia6380 exactly my thoughts too it so funny people go oh your addicted to weed when they are smoking cigarettes spend over 12 hours on tik tok and not have a life to live I only consider something and addiction once it takes your life over weed just makes life brighter more enjoyable and has more health benefits then negatives

[@sergiomissaglia6380]

@@weedmafioso I love you

[@weedmafioso]

@@sergiomissaglia6380 thank you I love the fact this is the most intelligent conversation I have had in most of my life

[@JesusistheFather_]

@@weedmafiosoweed brings peace

[@dmitritelvanni4068]

Idk man. The sheer relief caused by cbd have made me feel better than high at times. When you go from spending a day in migrane hell, to feeling clear headed and calm instantly from one dab of cbd distillate... that relief is intoxicating in its own right to me. Not impairing whatsoever, but just so liberating. Of course that's all subjective and scientifically inaccurate on my part.

[@KimHellemans]

that's awesome. happy to hear it's helped for you!!! Science can't explain everything yet :)

[@rebeccaallen4555]

Contact the name above 👆I strongly recommend him he's trustworthy he ship to any location man he got all kinds of psychedelic product stuff's

[@deniseward002]

The authorities make a big deal out of cannabis because it is such a huge threat to many industries. There are even warnings on many videos that talk about hemp - which doesn't have a high enough THC content to make a person high, and it has many industrial uses. But still youtube adds a warning. No warnings about pharmaceuticals though and they are one of the major causes of death. It's so obvious what they're up to. It must be great to have such a simple reliever of headaches. Think of all the people who could have been helped by cannabis but were prevented from doing so because...government.

[@tinicoleofficial]

I personally prefer CBD hemp flower over THC flower

[@Gngrcpl]

Glad it’s giving you relief.

[@williamhubel4643]

I use more cannabis now at 37 than I ever have and I am also more productive, healthy, and happy than I ever have been. It’s great for my mental health

[@ryanweaver962]

I haven’t seen a lot of the studies yet, but the concepts and real world data will elevate a lot. The patients and populations.

[@alexisfletcher6488]

Thanks you for the education !❤

[@natewhitelaw3759]

Wow this video really has a point of view at the end there

[@stringX90]

Are you taking about "some users may experience issues after chronic use?"

[@ryanweaver962]

The systemic approach with this system, above and beyond the cannabis usage but also how it pertains to it as well. The introduction into these matters with increased increased understanding of cancer and brain/gut and environment and amino acids or all sort of things. It’s a lot,

[@Deury._mota02]

Yes thanks video watched

[@larrytate1657]

Are there any studies going on now seeing If CBD will protect the brain from THC?

[@m1ghtysauc397]

Not one single person has experienced psychosis from smoking marijuana lol

[@zoemeow7677]

It’s not that important but it’s important because makes the brain healthier probably perhaps 🧠✨

[@sugargirlie72]

Can you please please do a video on CHS cannabinoid hypermesis syndrome

[@anthonysegura4020]

Dude That’s the worse ! I literally spent 7 years of my late teens 18-25 dealing with the worse imaginable stomach pains caused by high concentration THC levels. Always thought I had cancer somewhere in my stomach just because the way my stomach felt. Decided to quit weed 1st week major withdrawals also made me feel like I was dying. Fast weight loss and anxiety, irritability, depression yadda yadda then the magic happens after the 2nd week. Very little to no more stomach pains at all.. no inflammation, no pain. No feeling of vomiting. I couldn’t believe it. I should have listened to my G.I. Many years ago.. picked up smoking this year January 21st 2023 I told myself I wasn’t going to go crazy fast forward 7 months it’s been 2 days since I last smoked weed. Doing this for mental purposes as I’ve been having a hard time with psychosis, DPDR, Anxiety, Panic and Irritability. Day 2 seems better as I read in an online article that it takes 2 days for the body to start repairing the endocannabinoid system and about 1-2 weeks to have major relief

[@juanjohnsonvideo]

That was a very well put together video. Very tasteful

[@antisocialsecret7584]

Its help me to get rid of that pain in my legs..now I can sleep a hole night.

[@Dragon-Slay3r]

Baby leg?

[@antisocialsecret7584]

@@Dragon-Slay3r dont know what you mean. I crasch with my motorbike some years ago.

[@lawrencer908]

I have been having joint pain most my life but with cannabis it isn't as inflamed.​@@antisocialsecret7584

[@Donk618]

How about eating it 🤔

[@obeyy99]

The endocanabinoid system isn’t only located not the brain it one of our largest system of receptors and it starts from your Brain extending all the way down into the bottom of your feet

[@VelhaGuardaTricolor]

How about alcohol and coffee?

[@sergiomissaglia6380]

Coffee is a crazy ass drug I remember that the period I stopped drinking it I was all dizzy and just couldn't work... Never again

[@netro1629]

Can consuming cannabis lead to the accumulation of chemicals in the intestines after a period of non-use? Does the body deal with THC on the basis of a virus?

[@luciandavis5676]

How does regular use of cannabis effect the endocannabinoid. Can it throw off the normal system regulation? What about dopamine? Are there studies on this?

[@experimentalplanting]

kzbin.info/www/bejne/bnjWnod8rtl1j6s This video is nice. Although not maybe everything you ask for but they do talk about it. Actually continous use of thc can be damaging. cannabis contains lots of different phytocannabinoids though.

[@obyd7874]

Is this google?

[@boyznthewoodz770]

There is a lot more at play than just dopamine, but as with many other receptor agonists, thc lowers the bodies production of endogenous cannabinoids, leading to dependence and in the case of cannabis, lowered testosterone production. The same goes with opioids, amphetamines and all other receptor agonists. The body will choose agonists with higher affinity over endogenous ones as a means of saving energy, no reason to keep producing dopamine when methamphetamine is 100x stronger.

[@DarkstarAndrew01]

No, the video is incorrect in that assumption. There is no evidence supporting this claim, the correct way to say it is they are full of shit.

[@Plagolago64]

@@myninja0001 ha

[@the_faba]

I was going to like this video, but the like count is just perfect. I cannot.

[@JohnMastersDIY]

It was probably at 420 when they commented but someone now can be lucky 666.

[@ibrahimdeniz7308]

Visual distortions include seeing in 30fps in real life

[@sydgoings7058]

Wanted to make a correction that CBD is not considered psychoactive

[@CityChristina]

It definitely increases psychoactive effects when paired with D9.

[@LIVEMETRIX187]

@@CityChristinait actually makes d9 have less effect.

[@heartearth4104]

1:40 it's the direct opposite w me

[@msbluesman]

Correction its cannabis not can nibanous theirfore it canna bin oid system not can nib a noid and its not associated with psychosis 0:04

[@Professor__S]

Cannabis psychosis is genetic. We all have canabanoid receptors in the brain but that doesn't mean cannabis is for everyone. Predisposed disorder from your genetic background. I find it interesting that some cultures have more of a tolerance per capita then others.

[@simonlippok40]

It is, but who knows which persons do have a genetic disposition? Weed is causing significantly more psychosis than LSD and Mushrooms, which are wrongly known to be the evil psychosis creators. In fact, most psychosis come from Amphetamines and Cocaine.

[@experimentalplanting]

Cbd is not psychoactive

[@zaykray]

It still counts as psychoactive because it passes the blood brain barrier and affects the general wellbeing of the individual, a subtle change but does affect the nervous system, just not as intense as something like THC.

[@dr.nug7103]

Yes it is, but it’s none intoxicating.

[@KimHellemans]

@@dr.nug7103 psychoactive means affects brain cells; intoxicating means it affects consciousness. The two are independent of one another. For example, anti-depressants are psychoactive but not intoxicating.

[@dr.nug7103]

@@KimHellemans Ma’am that’s what I stated in my comment here:)Thanks for explaining it with more detail!

[@sergiomissaglia6380]

Personal experience. CBD is far more dangerous than the. I remember that the first time I tried CBD I just couldn't walk and use my scooter, it was so difficult that I wasn't even able to hold the wheel. With thc instead I can concentrate on anything for long periods and time just won't pass

[@Eskippy714]

I disagree in all of this. I used thc for many things particularly healing my anxiety and manic episodes

[@DarkstarAndrew01]

It's not addictive, I disagree with this point. It also doesn't effect the endocannabinoid system the way the video suggests, however it does take more if you don't take breaks occasionally which is solved by simply not taking cannabis for a week or two.

[@larrytate1657]

Not physically but of course anything that feels that good is going to be psychologically addicting. The same way a gambler who’s won a lot gets addicted to gambling. And with weed you always “win” cause you always feel high from it.

[@stringX90]

Agreed. It can be psychologically addicting

[@simonlippok40]

Dude what a bullshit! I am addicted to weed since years. When I don’t smoke, I get angry, can’t sleep at all and feel a little sweaty. Yes, weed is not as bad as Coke or Heroin, but it’s still capable to create a bad addiction. Just because it didn’t make you addicted so far (if that’s true), it doesn’t mean, that it’s non addictive. There is enough studies to back up that fact.

[@hassantariq3684]

Depression

[@nixnyxx5749]

🤭

[@giron822]

I believe THC abuse can be linked to the sudden outburst of mental health issues every one seems to have all of a sudden.

[@CrazyChickenLady92]

Thc abuse? You immediately sound ignorant

[@DerickClark-nu9mk]

@@CrazyChickenLady92 You can abuse almost anything including THC. Especially being psychoactive it has higher potential for abuse.

[@Roquea.207]

Stfo you have no idea what you are talking about

[@giron822]

@@Roquea.207 don't take my word for it you can't even write stfu properly

[@DarkstarAndrew01]

New research contradicts your assertions.

[@rebeccaallen4555]

Contact the name above 👆I strongly recommend him he's trustworthy he ship to any location man he got all kinds of psychedelic product stuff's

[@blackpillfitness9136]

Why don’t you tell us all about it then with your big fancy book words.

[@stringX90]

Care to cite your sources, DarkstarZeroOne?

[@mistercool3859]

Whenever someone tells you that marijuana is safe because it is a plant, remember that poison ivy is also a plant.

[@JesusistheFather_]

but you can’t smoke or eat poison ivy because you’ll die. people smoke and eat cannabis everyday and their life gets better . cannabis treats illnesses. poison ivy doesn’t lol think plus God created cannabis and said it was good

[@mistercool3859]

@@JesusistheFather_ I don't believe that marijuana makes anyone's life better. Maybe if you are sick with cancer, or you are struggling with HIV, marijuana can give you an appetite so you don't lose a massive amount of weight. But steroids and hormone treatments, under proper medical supervision, do the same thing. If marijuana does have other medical value, that still doesn't mean that it should be used recreationally. Cough syrup has medical value, but many teens have used it to get high, which is a bad thing. Marijuana has many negatives, such as panic attacks that can lead one to being hospitalized. It has also been linked to lung damage, cancer, breathing issues, poor cognitive development in its young users, speech and memory problems, loss of ambition and poor academic performance and work performance, low sperm count, and psychosis. It has also been linked to death through severe cyclic vomiting, look up CHS (Cannabinoid Hyperemesis Syndrome). Today, there are many media outlets that are making marijuana out to be a harmless drug, which is unfortunate. Marijuana, like alcohol and tobacco, is not safe at all.

[@JesusistheFather_]

@@mistercool3859 cannabis is not like tobacco or alcohol. cannabis has never killed anyone , but the other two , have and still do …. weed can be recreational because he made it before the fall of man. so adam could smoke it to have fun . there’s even things in your body just for cannabis and cannabis alone (cannabinoid receptors) literally name after cannabis. so people can smoke cannabis all day long if they wanted to and nothing would happen because God made things in your body just for cannabis. and people can’t overdose on cannabis, never have , never will . God said it is good . “Every moving thing that liveth shall be meat for you; even as the green herb have I given you all things.” ‭‭Genesis‬ ‭9‬:‭3‬ ‭KJV‬‬ so if you don’t like Gods creation i’m sorry but it’s not going anywhere and cannabis never hurt anyone . God said it is good ……

[@mistercool3859]

@@JesusistheFather_ To each his or her own.

[@yungeen_boi]

U gotta be Ed

[@LastDissidents]

Most important thing is how you get that THC into your body. Some ways are harmful while others are harmless.

[@thechrisman1345]

There is no harmless way to consume/ingest cannabis... What are you talking about

[@mbbb169]

@@thechrisman1345 Tinctures, edibles/drinks, patches, topicals - all virtually harmless. Also depends on your definition of “harmless” I guess, but physiologically speaking, those are the healthiest and again, virtually harmless ways of consumption. Smoking/vaping of course come with possible complications in heavy/long time users. However, compared to alcohol, cigarettes and other drugs, everyone knows cannabis is the least harmful from a physiological stand point.

[@thechrisman1345]

@@mbbb169 virtually harmless and harmless are different things. My main point is there is no "harmless" way to take any drug. Even if cannabis is the least harmful, you still have to give the right info to everyone about consumption

[@mbbb169]

@@thechrisman1345 Can you point to a study/reputable source that produced information stating that the administration of Cannabis Tinctures, Patches, topicals, dissolvable strips, and/or pills have been shown to cause harm to ones health? Assuming you're following dosing instructions correctly and assuming the products are of legal compliance, I cannot think of a single harmful side effect with the exception of maybe a little dry mouth? Is that what you consider harmful?

[@Jin_Studio]

@@thechrisman1345 how's "more harmless than anything in your medicine cabinet"? Pretty much anything as simple as aspirin or cold medicine can cause extreme reactions and even death. To my knowledge, no one has ever died from cannabis. Feel free to correct me with any reputable source

L.A.M.E.

So this is another well-funded anti-cannabis propaganda video.

[@jordanmedwell]

No. It’s the truth. May be hard to swallow for left wing pro cannabis zealots.

[@AndrewB221]

I have a Severe Traumatic Brain Injury, do any of you know what that is? Didn’t think so and research Phineas Gage, and Marijuana and CBD are saving my life

[@AndrewB221]

Yea and I’m a Veteran, so PTSD as well, and I was 28th I.D. 1/107th FA

[@lilianrobert9241]

They sell the best shrooms, dmt, lsd and other psychedelic products and ship discreetly to any location of the world 🍄🌍

[@sergiomissaglia6380]

You sketchy scammer :)

[@lilianrobert9241]

Pennyshrooms2--~~