CHRISTY KESSLERING a | STRESSED mitochondria tell nucleus: ‘you are different cell now!’

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presents episode 1877 | DR CHRISTY KESSLERING w/ Jesse Chappus
In cells we can burn glucose and fatty acids for fuel…
-happens in mitochondria
Mitochondria dictates what is going on in that cell
-if damaged, start sending our stress signals
-even to the nucleus: "you are a different cell now!”
As mitochondria become more & more
damaged, they tend to switch from
using fatty acids for fuel to an
anaerobic pathway…
They burn glucose as a preference, and need more &
more of it to sustain themselves…
-cell transitions into 'every man for yourself’ type
Healthy cells all live in community doing our own jobs:
-liver cells do what liver cells need to do while taking
up only as much space as needed
But--as cells become damaged &
revert to 'single cell organism’ just
trying to survive
These damaged cells, needing more & more glucose..
-in this anaerobic metabolism, even though oxygen is
present [known as Warberg Effect]
-start upregulating their Insulin Receptors
-this happens before cell becomes cancerous
As cell becomes more proliferative, so
excessively upregulate insulin receptors
-tell cell: lots of glucose!!
-cell uses glucose carbon to grow
more cells
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