Cracking the Code of Aging: Inside "Project Blueprint" | Bryan Johnson

Bryan Johnson has been many things in his life, but the founder of Braintree Venmo's current passion is being - in his parlance - a "Professional Rejuvenation Athlete". Over the past two years, Bryan developed Project Blueprint, a comprehensive health regimen designed to reverse the aging process and increase longevity. After struggling with unhealthy eating habits, Johnson "fired himself" and dedicated his time to researching and experimenting with different health and wellness techniques. He used data-driven approaches to optimize his diet, exercise, and other lifestyle habits, with the goal of improving his overall health and extending his lifespan.
In his first year of following Project Blueprint, Johnson achieved remarkable results, reducing his epigenetic age by 5.1 years in just seven months. This amounts to an average age reversal of .73 years per month, a significant accomplishment in the field of anti-aging research.
One of the unique aspects of Johnson's approach is his gamification of the age-reversal process. He created The Rejuvenation Olympics, an online leaderboard open to the public designed to motivate himself and others to stay on track with their age reversal goals and to have a public forum to share protocols and validated results for age rejuvenation. This approach helps turn the often daunting task of improving one's health into a fun and engaging game.
Johnson also employs a problem-solving approach he calls Zeroth Principle Thinking, which involves breaking down complex problems into their most fundamental components and solving them systematically. This approach helped him create his Goal Alignment Problem, which involves aligning his daily actions and habits with his long-term health goals.
One notable aspect of Project Blueprint is that it's available to anyone, free of charge. Johnson has made the information and tools he's developed publicly accessible, with the hope of helping as many people as possible achieve better health and a longer lifespan.
Overall, Bryan Johnson's Project Blueprint represents an innovative and data-driven approach to health and longevity, with potential implications for the broader field of anti-aging research.
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[@davebudge4526]

I love how Bryan is so open and good humoured about how eccentric he might be perceived for doing all this ,he's not defensive or arrogant at all and you can tell he is really enjoying this journey he's on.

[@safiahnordin5116]

Exactly, thats why i follow this guy👍

[@runecscapeman]

Warmed up my Super Veggie to eat while watching. I love the confidence Blueprint has given me. The love for myself has increased 10 fold. SUPER GRATEFUL for Bryan leading the way on this life long endeavor.

[@jreverie7018]

Keep it up! Another day not spawning in Lumbridge is another good day

[@familyofstars]

Whoa.. Bryan is ex mormon. As someone who was excommunicated at 17 y/o for apostasy, I am even more invested in seeing his success. I've been criticised for aiming to maintain my bodily purity, as if it were some type hangover from Mormon indocrination, but to me it is just the logical and loving way to be towards my body. I tried the bad food and the alcohol...and that was a recipe for misery. I very much listen to my intuition... But I think approaching things with this scientific method is so useful and has inspired me to keep moving towards my own health goals.I love the data collection. This is a fascinating experiment. I would love to see humanity as healthy and as joyful as possible. Thanks Bryan! And thanks for this interview James!

[@waynehedd]

I love how Bryan keeps trying to promote basic sleep and exercise over buying his supplements or meal plans.... so authentic this guy!

[@dledman]

11:45 thank you Bryan for your generously sharing this valuable trailblazed information. Have been adopting Blueprint for the past month, strictly too and have never felt this incredible in my life (stronger, more mentally acute, creative, calm, social. My cardio and sexual performance had the biggest improvement). That old evening Dan came in and convinced me to celebrate a work achievement and staying on this protocol with some Chinese food - I feel like absolute shit, poisoned and bloated. Definitely determined now to stick to the protocol now more than ever.

[@juliafisherlmmortalbeauty9119]

That’s amazing!!! Well done! I’m on the edge seriously considering starting just need to prepare myself mentally x

[@maxivy]

James, you asked thought provoking, detailed, nuanced and original questions to Bryan. Really glad you did. This vid needs more views.

[@HvdHaghen]

Yes, but what was the answer on the question how Bryan's memory was? I think while answering he had forgotten the question.

[@marcell.paumkirchner]

These reporters and podcasters are so professional and unique that every interview is 99% the same with Bryan. Congratulation!

[@slava1669]

He’s is on point!

[@angry_Australia]

No he isn't. Look at him in 2015 vs now. This guy is clearly prematurely aging. Idk why he lies saying he's getting younger because he took 60 pills a day LMFAO

[@oijgg3p]

​@@angry_AustraliaThose pills are vitamins and metals. And his skin in white because sun makes skin die faster.. he is way healthier now. Also, if you faking listened anything, you would learn to read the data, not look and express your dumb opinion. This guy does not have an opinion when it comes to health, data says it all.

[@rl7012]

@@oijgg3p So you are telling us to not believe our eyes just believe the lies. Yeah right. Do you work for Pfizer by any chance?

[@addictedtochocolateandcoff9582]

@@angry_Australia yeah he looks 50 not younger like he claims

[@ituzovskaya]

Great conversation of two very smart people, so pleasant to hear, my brain is really enjoying. Probably the most informative interview of Bryan about the Blueprint. Thank you both!

[@TheJamesAltucherShow]

Glad you enjoyed it!

[@Ben.morton]

30:07 = the most honest answer I’ve ever heard in an interview. 🙌

[@stopwars8642]

wow James and Bryan together, yes on 1 2 3

[@aftabkahn3366]

Good job and helping human fellows to change their life's ❤

[@peterz53]

@43 min on sleep tips: I can attest to those tips. If I eat within 3 hours of bed time I can readily see the negative effects on my Oura data and how I feel the next day. Same with alcohol, although and a single drink with my meal seems to be OK most nights, but I rarely drink any more. One thing that I haven't delt with is my dog who sleeps on my bed. I know she wakes me by moving around or crowds me, but don't have the heart to crate her. I also agree based on my experience; the psychological benefits of good sleep are enormous.

[@barath4545]

I've had okay results with a nightcap, but you are 100% right on the food - All the well farting etc and whatever goes on while sleeping fucks with my quality. Had anxiety (over work and relationships) and the nightcaps coupled with audio ASMR or reading a book has helped me GET to sleep after which the quality at least improved overnight, rather than having no sleep till 2-3 AM.

[@slava1669]

Thanks for this

[@GS-rw9og]

Thankyou for endeavoring to eventually provide in home access to quality, brain monitoring and promote excellent health

[@robertmariano]

I remember listening to this on the podcast. Watching it, I see how young this guy looks. But missing bagels, that’s going to be difficult. This reminded me of your David Sinclair podcast and Dr. Gundry podcast. Good stuff

[@TheJamesAltucherShow]

Thank you! Yes, missing bagels is going to be really hard!

[@fredwinslow744]

I’m following some of the blueprint But my favorite part of day still was the 1/4 bagel from bubbis New York bagels ( Toronto ) Cheers James for a good interview

[@dledman]

I thought I would miss my old favourite foods too. But now after being on Blueprint for awhile now I feel toxic and bloated when I eat those foods. The awful experience helps reset your psychological desire for such unhealthy options.

[@deeprollingriver52]

It takes a lot of money, time, and effort to stay young. It’s exhausting. So, I decided to just enjoy what time I have, be as healthy as reasonably as possible, and RELAX!

[@gixane4077]

Excelente entrevista. Muchas gracias a ambos

[@1ron0xide]

Bryan is aging exactly as fast as the rest of us: 1 minute every 60 seconds. Don't believe a word to the contrary

[@fr1571]

I love Bryan Johnson and what he’s doing. The host and his comments and questions are terrible though. He’s also, at times, slurring his words and sounds generally uninformed.

[@tex959]

He needs to get on Brian's health plan😂

[@lindalembeck7286]

Bryan Johnson doesn't distinguish the fact that his mind is also telling him to follow his new protocol and to get healthy. Completely demonizing the mind in its totality is an inaccurate way of describing the more primitive aspects of the mind from what can be called our higher selves. Self mastery, which has never been easy, is the goal. It makes me sad to see younger generations giving up on this and thinking AI should control their lives because human minds are too primitive. The human mind can do things that a machine will never be able to replicate no matter how advanced the programming, because the mind surpasses programming. I realize this idea is not in vogue with most academics.

[@sugarcravings1797]

The mind feels, thinks, wills, etc., it's not exclusively 'wills'. There's more than sankhara, and there's something greater than the mind: consciousness.

[@CheapSushi]

I bet ChatGPT could make a better argument about what point you were trying to make better than you did.

[@rl7012]

@@CheapSushi I bet it could not.

[@516estrela]

Wife: did u look at her ass? Bryan Johnson: "I dont want to confabulate"

[@planetmuskvlog3047]

Awesome conversation. You can do it James! How’s it going so far?

[@observerone6727]

Almost all people think that their mind/awareness is one being. It is not ! There is a very large/vast committee in our head - makes sense since we have 100 billion neurons, millions of complex separated regions. And there are parts of our own brain that are not our friend (such as choiceless addictions that don't give a damn about us long-term). If a person is lucky, they find their true decisive survivor.

[@christopherwood8159]

love the ideas, very interesting. Need a cheep way to test for the data at home so we can have more people competing in this!

[@jJust_NO_]

i can comprehend this.

[@WomanFromTheMoon]

It seems like Bryan is the perfect human, let’s clone him🙈😩 we really need more people like him with all his state of mind, self organization , self caring and respect! Can not stop watch all his interviews and video,literally 😂 Bryan, pls more babies 😂

[@leiladasha]

OMG, what's wrong with you ?

[@StancyInTheCity]

I find it interesting, though that he had plaque buildup in his carotid arteries. I seem to remember that from one of his videos. He had to have it addressed at some point.

[@CheapSushi]

Was it plaque buildup? I think it was stenosis (partially due to genetics; smaller arteries than on average) that worsened due to bad posture

[@fredwinslow744]

I’m following some of the blueprint But my favorite part of day still was the 1/4 bagel from bubbis New York bagels ( Toronto ) Cheers James

[@ericaosani8492]

do Dual N back test to test memory and tell us your score

[@hisairness28]

Caloric restriction without weight loss?

[@fredwinslow744]

Where did you go ? How long have you been on u tube ?? James.

[@danypell2517]

he should loook into okinawan

[@orion9k]

2000 calories and 100+ pills? I am going to bet that those 100+ pills are adding in at least 500 additional calories.

[@ericaosani8492]

do you get gray hair

[@The150YearOldMan]

"No one else is doing it better than Blueprint"... (?). There are always greater people doing things, to be encountered. In ...The Quest for Healthy Longevity, the protocol is three meals per week. Basically a 46 hour fast, three times a week along with a 70 hour weekly fast being sustainable (key word, sustainable). This quest approach heavily competes with Blueprint, in extending life span and health span....

[@CheapSushi]

The difference is no one is doing it with DATA, actual measurable science based on facts. Only he is. People can say and do anything. But he is backed up by numbers.

[@soez_strg6166]

@@CheapSushi It's meaningless because he chooses which markers he measures. For example, he doesn't measure DHT, estrogen, prolactin levels, even if they are important for normal cognitive functioning due to him crashing his DHT levels to keep hair. He also has to take steroids and GH to be able to run his nonsense protocol due to it being so unhealthy and is essentially infertile for this same reason. Not to mention all the mental side effects. He is either delusional, or a fraud. "+ Free testosterone index (FTI) biological age reduced 20 years" He writes this on his website when his protocol makes him impotent and he has to take exogenous hormones to have that level. I liked Bryan at first, but the inconsistencies keep piling up and I'm now convinced he does this purely for clout or money.

[@raid5098]

@@soez_strg6166 Proof? Source? I'm not doubting you but I want to see.

[@BestLifeMD]

No. He’s not following telomeres length which would be the most correlated with aging. Great question, James. I had wondered the same.

[@slowslug3247]

Only 20 yr old will fall for this, so obvious

[@randomfocus1549]

I like Bryan and all hes doing however regarding the vegan diet hes on i feel he should note hes supplementing with Testosterone and HGH.. id like to see his system run, exactly as it stands calorie wise but include animal fats.

[@CheapSushi]

He's also using animal sourced collagen. His stance on veganism or carnovire, etc is neutral. He's just doing it on personal preference based on his viewpoint about some aspects of it. If someone wanted to follow a similar protocol (blueprint) like him but on animal heavy products, he wouldn't object.

[@nodelayfordays8083]

If anything this shows how tme consuming and expensive it is to maintain good health, how complacent with a poor not even medicore health care system we've grow to be.

[@KS-yp1jl]

Wrong. What he's doing is expensive in terms of research, but the basics of the protocol are affordable to pretty much anyone.

[@nodelayfordays8083]

@@KS-yp1jl the pills can add up and the medical equipment or seeing a doctor to get the same tests he has which is key to know what amount of each pill/diet works for you personally also adds up and takes time.

[@CheapSushi]

It's time consuming on his side because him and his team are doing everything they can to make things miserable and text different theories, etc. He's trying to figure out what works and what doesn't, what's worth doing or not, etc. It doesn't mean every single thing he is doing is necessary or worth it. But he's testing as much as he can to figure that out. The actual Blueprint won't be as time consuming.

[@martinplasse174]

what's up with the nail polish/color?

[@ilyabykov2437]

The guy who can afford to spend so much money on spa procedures must follow certain agendas.

[@leiladasha]

being weird

[@slava1669]

Almost as if our mind is the parasite

[@fredwinslow744]

Society is the parasite Our mind is the host If you can’t go back in a Time Machine to paleo era This concept of Firing your mind in regard certain decisions as a habit and way of life is the exact right concept to change the game It’s just that not many people will see the life gold at the end of the lifestyle rainbow Blue print will exist and people will still prefer to have a gun with bullet for the societal parasitic lion

[@tex959]

Yeah, more specifically the reward center in our mind that regulates dopamine. 100 years ago or 1000 years ago, It wasn't as big of an issue as it is today since we now have too much access to the dopamine hits.

[@john_says_hi]

the left hemisphere, read "the matter with things"

[@nagilum]

I need t get a new bed.

[@leiladasha]

agree med beds now!

[@john_says_hi]

That'd be funny to make a deep fake of him speaking as a toddler. He's deaged completely.

[@orion9k]

But must people work in production or maintenance service, they are at the bottom of the coorporations and their blood is sucked out of them as soon as possible to keep a high productivity and the top management dont give a rat arse about them as soon as their performance starts to decline, they just get rid of them and hire new young fresh meat, this is how cynical "our society" is. Your program is for the midle and top manager and wealthy succesful entrepreneur who are not having their life sucked out by some greedy employer 🙏

[@leiladasha]

his BS protocol apply to him only

[@blobtv7444]

Every video I've seen with Bryan he looks yellow, something is off with this guy even with all that money and testing

[@CheapSushi]

It's because he's a ginger naturally and he's at 5% body fat (proved by an MRI), so his skin is thin. There are multiple types of melanin, and some people are genetic predisposed to more eumelanin, or more pheomelanin, etc for example.

[@juliafisherlmmortalbeauty9119]

Yes that is the natural undertone of his skin. Check out the amazing texture and no wrinkles years younger than his age!!!! X

[@leiladasha]

his filter

[@leiladasha]

​@juliafisherlmmortalbeauty9119 he did lasers yes he does have wrinkles - filter hello?

[@arielbender6173]

All the chit chat comes to one conclusion every time not onky in beating aging on just about everything that exists All you need is loads of disposable cash and nothing else to do .

[@ilyabykov2437]

Is he using a face filter

[@leiladasha]

yes

[@optimizeforall]

I noticed when you and your guest speaker at the same time, you ought to continue speaking instead of allowing your guests to speak. I prefer to hear your guest speaker over you, it's the reason I came, I don't think it was that egregious, just some critical feedback

[@leiladasha]

crack code ? You have to get upgrades DNA activation

[@bgrobbins]

i know his blueprint is a great protocol, but he is not leading the absolute leaderboard. there are a few other people ahead of him, mostly women.

[@tex959]

Who are your favorites in health and wellness?

[@shoshanakirya-ziraba8216]

Probably an old Japanese lady who is eating her traditional food

[@CheapSushi]

I didn't know he was competing with people on some leaderboard....come on. Dude is just trying to do things as scientifically as possible, so other people can make their own judgement call.

[@leiladasha]

far more better result and no BS blueprint

[@mr.s7031]

He needs to get a refund

[@slowslug3247]

Baloney 😂 he looks old even with the filter/ makeup on

[@leiladasha]

57

[@jonaswunderkind4580]

He looks like pale 40 year old

[@CheapSushi]

He is a pale 46 year old. His point isn't about looking like an 18 year old while 90 years old or something. It's about functionality long term.

[@soez_strg6166]

His cognitive performance is surely negatively impacted. He takes too many hormetic stressors, blunts dopaminergic signalling and eats in a kcal deficit every day. Bryan, needs to be honest about his experience. His fans will get hit by sides like a train if they run this nonsense protocol.

[@addictedtochocolateandcoff9582]

how many calories does he eat

[@leiladasha]

cannot believe he promote this starvation diet with pills - people will get sick

[@leiladasha]

​@@addictedtochocolateandcoff95822000-3000

[@gamblinguru33]

Entropy has nothing to do with aging. I wish people would stop perpetuating this

[@muhammadmoslem2046]

How come it has nothing to do with aging?

[@gamblinguru33]

@@muhammadmoslem2046 humans aren’t closed systems. We can export entropy to our surroundings. The difference in entropy of a 20 year old and an 80 year old is negligible.

[@CheapSushi]

@@gamblinguru33 prove it with some data

[@gamblinguru33]

@@CheapSushi There's nothing to "prove." Humans are an open system so the second law of thermodynamics doesn't apply to us with respect to aging. Sure, we have to counteract entropy to survive but this doesn't result in aging. The entropy of two people with same mass are virtually the same with differences arsing from the degrees of freedom of the water molecules. There are species on this planet that don't age (a species of Jellyfish, hydra, planaria). If entropy caused aging then this wouldn't be possible.

[@zackbrown5201]

2 million dollars a year to look like 50 year old Grandpa. All he needs is fatty steak, eggs and butter . Blueprint for 20 dollars a day !!

[@WomanFromTheMoon]

Wait a bit😂

[@WomanFromTheMoon]

It is about the data you need money to make all those measurements… but food and sleep regime can do everyone. will power and intent- go for it!

[@zackbrown5201]

@@WomanFromTheMoon he is just making it worse ...we humans are not vegans . All he is doing is aging his skin . Collagen found in animal diet surpass any plant based collagen

[@leiladasha]

He does not look like a grandpa and you not supossed be at 50

[@TestimonyPony]

Mormonism is not Christianity