Cure for Hearing Loss FOUND....& then LOST 😥 | FX-322 & FX-345

Researchers found the Cure for Hearing Loss and Tinnitus & then they lost it. Doctor Cliff Olson, Audiologist and founder of Applied Hearing Solutions in Phoenix Arizona, discusses the journey of Frequency Therapeutics Molecular therapy drugs FX 322 and FX 345.
drcliffolson.com/
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[@alwaysmorecowbell]

I didn't know they were also curtailing 345. That's bad news. I have an acquaintance who was in the precursor 322 trials, and the tinnitus in his treated ear was completely resolved.

[@FurkanTopal]

is it possible to get that treatment?

[@CharlesSneed-c3l]

I suspected that it would. It's a crime against humanity that they won't continue to move this drug forward for that.

[@homeontherange733]

@@FurkanTopal No, i signed up for the trials only to be told they were not doing it anymore.

[@thomasallen647]

Where are these people from the trials? We need confirmation that it DID or DIDN’T work.

[@gundamcollector77]

Companies that snuff out research like this that can improves peoples lives for the better for the sake of profit need be tried for crimes against humanity.

[@DrCliffAuD]

Who snuffed this out? The research proved it didn't work. There was a much bigger profit motive to make this actually work.

[@emilmann7883]

​@@DrCliffAuDI think what he meant was, that the hearing aid companies did somehow have a hand in shutting down the trials or manipulating them in order to fail because a drug like this would absolutely destroy them...

[@rrealmezz]

I love how my tinnitus became severe exactly 2 weeks after the cure failed this ringing is insane and the new hyperacusis which i never have ever had in my whole life is making it better, i hope by 2050 or something we could atleast restore hearing, I wish to live a silent life in my 50s at that time

[@danielbroomhall8882]

it is hard to live with severe tinnitus, I do. I just live day by day, but not sure how long I can live without taking my own life.

[@josephortiz6371]

Please tell someone who loves you or you love how you feel before you make a big decision.

[@fallback8314]

how old are you and how did you get tinnitus?

[@rajasharma8257]

Doctors and hearing aid companies will never let any drug be out in the market that can regenerate inner or outer hair cells. As they will suffer heavily from this.

[@MohamedAlshareeff]

لماذا نحن نتعذب 😔

[@enot17256]

I will make you happy, it turns out there is a remedy without side effects, here is vitronectin 180 alklometasone 8 vinpocetine 8 piracetam 12 elipticin (antitumor agent) 170 5-fluorouracil (antitumor agent

[@eddietulane6594]

bruh hearing aid companies dont have enough money to pull that kind of stunt. Plus, this hearing solution would rake in more money than hearing-aids so by your logic there would be a group who takes out the hearing-aid companies, to make themselves richer. stop thinking in these baseless conspiracies

[@mohanraavi-hj6lm]

Sir please urgently research on sensorial hearing loss cure during 2023.And released Medicine for hearing loss cure.

[@briandeveney4948]

I'm not a man of science but a gentleman who was on the local news in NJ that went to San Francisco for one of their trials got his hearing back after the fact. They had a long segment about it and a HUGE article on the internet. So why did they just go belly up from a success story?! False hope and it kills me mentally day by day.

[@DrCliffAuD]

Weaknesses are always revealed in larger Clinical trials.

[@meric12131415]

​@@DrCliffAuD indeed it's so

[@stephentackett4064]

Link to the story please.

[@jackburton307]

@@DrCliffAuD except that it had a significant success rate with noise induced hearing loss and not age related hearing loss. Why throw out the baby with the bath water!?

[@meowchat6175]

For your information, the FDA is one of the most corrupt government agencies in the country. Big pharma practically owns the FDA and that's why they cancelled FX322 & FX345. The orders came from the FDA to terminate the program!

[@mightyoakk]

They didn't loose, it's all business, the medical industry truly doesn't care about the general public's health, only if you're rich or have a good amount of money to spend privately you won't be able to use all the advantages medicine has given us. An ear drop that contains 7-8DHF can easily be a potential cure for Sensonural hearing loss! but imagine an over counter drug that cures hearing loss! a billion $ industry goes under.

[@ExistentialismOnPromNight]

They never discovered the cure. The participants lied during speech perception test trying to get into the clinical trial. They even wrote about it in the paper.

[@mightyoakk]

they recently even found out that nootropics are very effective with cochlear implant patients, making the brain adapt to the situation better! there is something here that they are not doing enough research on! or not getting funded properly!

[@mightyoakk]

I'm waiting on an MRI 8 months away! they don't care man! I saw three different ENTs in the past month noun of them helped me, they didn't even know what 7-8 dihydroxyflavone was! I showed them the research and they were like ha that's interesting! They don't care!

[@orange_turtle3412]

Hopefully some company eventually takes up research on 7-8DHF and puts the public’s health over money. Hell if it works they could still get filthy rich from selling their product.

[@mightyoakk]

​@@orange_turtle3412 Yeah!

[@dipeshyadav8553]

Please give an update on NHPN 1010.

[@swethareddy3904]

The more we hope, the more we lose, it is more cynical than life😭

[@leaderff788]

Hello didi I'm also from India bohot zindagi kharab hogaye hai kuch samaj nahe atta kya karu me

[@garywillhide9977]

Hopefully one of the other companies, working in this sphere, can buy their research. ✌🌱

[@bk6555]

No, they buy the company to snuff out that research. It happens all the time in medical and non-medical industries.

[@ExistentialismOnPromNight]

@@bk6555 No one in the right frame of mind would buy it. The research itself was bullshit to begin with, if you care to look at the nonsensical way they measure the improvement.

[@meric12131415]

​@@bk6555 that's correct you'd be surprised

[@emilmann7883]

​@@bk6555do you have any proof for that or is it just speculation?

[@0700083edu]

We all know how private equity firms work. They are optimized to make a profit with as little labor as possible. Real science involves a lot of expense and no promises.

[@Sauravkumar-ys2rw]

We have treatment for life threating aliments but we can't treat deafness.. Deafness is around for in human history for very long period of time but the efforts to completely cure it is still not visible.. I want to ask why

[@harveyspecter1653]

Sad to hear this. Thanks for the update Cliff.

[@MelvinOhio]

Sounds like hearing aid industry bought them out.

[@482jpsquared]

Not likely. Different industries and priorities.

[@naelbeno6249]

Facts

[@bk6555]

​@@482jpsquared Very likely. Don't kid yourself. It happens among all industries.

[@DrCliffAuD]

The hearing aid industry is peanuts compared to the pharmaceutical companies. If there was promise in these drugs, the pharma companies would have made it happen. The cure is worth Billions if not Trillions!

[@ExistentialismOnPromNight]

They never discovered the cure. The participants lied during speech perception test trying to get into the clinical trial. They even wrote about it in the paper.

[@DailystuffAB]

there is no hope for us deaf people. Everyday i am crying, feeling depressed, life is hard and struggle. Its better to be dead.

[@orange_turtle3412]

There will be a cure. Dont worry. Eventually, they will figure something out. In 5-10 years we’ll have another situation like fx-322. And if that one fails too, we’ll have another after that. Humanity wont give up all together. And especially if hearing loss gets as bad as predicted by 2050, it will become more of a primary focus to get it fixed. Hang in there man. Treat your loss however you can now. Think of it as a temporary fix (even if “temporary” means 10-20 years in this case) FX-322 was one failed experiment. There will be many others soon. And at least one of them will eventually succeed.

[@joebiden46president52]

@@orange_turtle3412 we have 5 drugs to restore hearing in trial

[@orange_turtle3412]

@@joebiden46president52 At least. But none have the funding to progress

[@Aviorrok]

The cure is coming I’m sure

[@DailystuffAB]

@@Aviorrok not in my lifetime and i will become 41 in april. I gave up everything, my dreams to get married and have kids. Coz there is no hope

[@louis_ricks]

Dude please 🙏🏻 I would give anything to restore my hearing. 😢 This is obviously all bogus, because of that “silver lining” which is the hearing aid business….

[@hauptmannbalalaika]

Exactly. The hearing aid industry, even the battery industry, is not keen.

[@koolchem6653]

Dr. Cliff, what do you think of NHPN-1010, by Hough Ear Institute? It seems they have found something that works but are having problems getting it to Phase II trials. I would think this would be a blockbuster and any pharmaceutical company would take this up.

[@mostguitarswins]

Well, that's unfortunate news, but hopefully someone else will take up the research; there's an enormous market/business opportunity for a therapy that would cure hearing loss.

[@yilmazbican2818]

This inc. take up the research.

[@wenciferhernandez7058]

I refuse the idea of getting hearing aids I don’t have hearing loss but I do have tinnitus and this drug was the only think giving me hope that one day, everything will go back to normal. Now that I hear that it’s all going to be thrown to the trash is just too much for me to process, i understand that I shouldn’t expect this drug to be perfect but still, at least try to continue to work on it and not just say “that’s it we give up”

[@visnikvisnik22]

It's a sloppy company. They wanted money, but not for research. They knew it would be a failure.

[@hotplug56]

All is not lost as Skylark Bio has picked up one of the key researchers from FT.

[@patilsandipb]

This is really bad news for me who waited for hearing loss cure. I stopped believing in God since I got this as I haven't done anything bad or thought of bad things for anybody in my life. This depression is killing me everyday. Nobody understands whoever around me what's going on with me. Everybody feels I am dumb. This World doesn't care what you r going through even if u say it. There are so bad people who r having no problem then why chose me? So i can die early?

[@0700083edu]

Sorry but you have never believes in god. Going to church doesn't mean much.

[@benjaminubayyed1865]

But what do you do if you have hypercusis? How do you amplify frequencies that you can no longer hear without amplifying ordinary sounds that already bother, hurt and further harm hearing?

[@naelbeno6249]

I got it!!!!

[@jctango]

Although the video has quality the title is misleading. They never did "find" the cure. They just saw some positive results they couldn't replicate.

[@paulbainjr]

I think more study should go into the placebo effect I think it works to some extent.

[@stever8574]

I kind of think that initial study was either deeply flawed or outright BS.

[@DrCliffAuD]

I agree.

[@Peter-wv5pl]

I can see that. Get a few participants to claim success so they can get more funding to keep researching. However, that doesn't explain why they completely gave up. You'd think they'd ask for more funding so they can iron out the wrinkles. I think Big Pharma felt threatened by it. It was a cure for hearing loss. I know Big Pharma doesn't have drugs for hearing loss. But they do have drugs for depression, dementia, and other issues created by hearing loss.

[@sidneyalvarez5913]

What about the spi-1005? It's already in phase 3

[@ahmadm.nawafleh2423]

It is for menieré disease…

[@thomasjetter2683]

Isn't that "only" for meniere desease?

[@misscritique8863]

Where’s the hope?

[@sathishgujjunuri7677]

Tq .from 5 years iam facing hearing problem..🙄i can hear sound but i cant understand what people saying..i mean i cant hear words clearly...iam partially deaf pls help me🥹🥹

[@prakashrajias7967]

Same here😢... Please help us

[@mohammedshahin6422]

i've came through Bionics Institute in Melbourne, Australia developed nanotechnology to deliver drug into the inner ear. will there be any hope from their side? please share if there is any update

[@orange_turtle3412]

Their research is in very early stages. I wouldnt expect anything significant from them for another 5-10 years.

[@amertaemaa6559]

They found the cure,and then they lost it!!!???? IS THAT AKIND OF MYSTERY!!!????!!!🤔🙄😶

[@ExistentialismOnPromNight]

They never discovered the cure. The participants lied during speech perception test trying to get into the clinical trial. They even wrote about it in the paper.

[@irenerubaum-keller5941]

Really wanted it to work. Bummer!

[@ajaysirbiharwale]

Sir Namaskar 🙏 .I am Ajay from Delhi 🇮🇳. India. My daughter Ananya 7years old has profound loss of both ears upto 90%. Is there any medicine ???

[@DutchGuyMike]

Nothing really sadly except protecting her hearing as much as possible

[@corymarcotte5853]

I find this interesting. I did follow in with hearing aids. Maybe this is a one off. But my hearing has gotten worse with them. Not sure what to do at this point.

[@ASBOAIRLINES]

I’ve started wearing hearing aids at 17, now 33. Throughout the years my “good ear” got to the same level of a “bad one” meaning now I have moderate hearing loss in both ears and “doctors” don’t know the reason for it. Worth mentioning is that I would rather avoid loud parties, using headphones and taking drugs etc. just had a few pretty traumatic and stressful events in life. It’s sad how they don’t tell you that wearing just one hearing aid might result in worsening the “good ear” etc. I hate not knowing what is causing the hearing loss. Just sad.

[@derp4687]

Slightly off-topic, but why do we humans need the ability to hear frequencies between 20 Hz and 120 Hz - frequencies you would hear much better from a good-quality subwoofer than from an ordinary speaker - when just like all of the frequencies between 12 kHz and 20 kHz, they’re not critical for speech? Why would the ability to hear low frequencies not critical for speech be any more important for daily living than the ability to hear high frequencies not critical for speech is? Both of those abilities are absolutely vital for full enjoyment of high-quality audio with very good bass extension, boosted “sub-bass” and very good treble extension, but neither of those abilities are absolutely vital for spoken communication, so again, why would the ability to hear frequencies between 20 Hz and 120 Hz be any more important for daily living - without the high-quality audio involved at any point! - than the ability to hear frequencies between 12 kHz and 20 kHz is?

[@orange_turtle3412]

Why do we have tonsils? Why do we have an appendix? Why cant our ears heal like chickens can? Evolution is weird.

[@mariog4615]

Hello Dr. Cliff and team! I really would like to thank you for your videos and material. 6 months ago I experienced severe tinnitus in my left ear, right after a heavy sinus infection. I went to my ENT who said I had mod to severe hearing loss in both ears, and said it was most likely NIHL, which is weird as I am not really exposed to loud noises. Being in my 50's and having no prior hearing issues this has severely depressed me. I am still trying to piece this together, but I have to say your channel and videos have given me hope and perspective. I am really hoping for some type of treatment. There is a Harvard stem cell study that sounds promising. Also a question...is there a danger to your brain or nerves from over-isolating against general noise with earplugs? I heard this may be detrimental in the long term. Again ty for your work and info, it has really helped. Cheers. **correction it wasn't a stem cell study, it is a molecular treatment and Dr. Cliff covered it in an exciting new video.

[@faruqbadlani]

​@@valdemarsyk3985how? any guidence?

[@Максим-у2т4щ]

​@@valdemarsyk3985, destroying of hear cells is just a theory, cause now we dont have technology which can help to find a real problem in inner ear.

[@b1225-]

Spi-1005 nhpn-1010

[@tomskdog11]

I’m certain molecular therapy will be a thing one day. This is just another failure that companies like frequency will learn from. Let’s just hope it isn’t another 2 decades! I have normal hearing by the way. I just love my loud music and don’t wanna kick myself in the foot later on knowing I will never hear the same again 🙂. For those suffering, please don’t say to yourself there will never be a cure, because these people are smart as anything, and they aren’t going to give up!🤞

[@sarahspindler2914]

You could just turn your volume down or wear ear protection before it's too late 🙃

[@BROTHERWITHOPENEYES]

Maybe some insight into why freq theraputics have dropped everything....$$$ You dont disrupt such a huge status quo that easily : "[220+ Pages Latest Report] According to a market research study published by Custom Market Insights, the demand analysis of the Global Hearing Aids Market size & share revenue was valued at approximately USD 10.23 Billion in 2021 and is expected to reach USD 11.5 billion in 2022 and is expected to reach around USD 17.68 Billion by 2030, at a CAGR of 4.9% between 2022 and 2030. The key market players listed in the report with their sales, revenues and strategies are GN Store Nord A/S, Starkey, MED-EL, Widex USA, Inc., Sivantos Pte LTD, Phonak, William Demant Holding A/S, Medtronic, Benson Hearing, and others"

[@Th3MagicBullet]

FREQ CEO should be jailed for fraud.

[@jaimiemcevoy6887]

So...the cure was not found, it just didn't work. I enjoy your videos, and it isn't up to your standards to have an innacurate title like that. I had not seen your previous videos on this research, and the idea that a cure had been found - even if it had been lost somehow - gave me false hope that there was something that simply needed to be redone.

[@orange_turtle3412]

Hes saying that there was a trial of fx-322 that did show significant improvement, implying that the drug did successfully cure hearing loss at that time. But somehow that ability of the drug was lost in further development. The drug actually did appear to cure it for a time.

[@amritajmt610]

Sir my hearing loss in right sight how can I cure and hearing back😢😢😢

[@orangeseb786]

Bhai pehle Maine ignore kiya phir mereko slight hearing loss hogya 🥺😣

[@CarlosAlexandre-ok3zo]

Para um bom vendedor de aparelhos este vídeo é uma excelente notícia...não é dr?

[@emmanuelperez6217]

I lost a lot of money with frequency Therapeutics... I closed my position. I still have a position with Decibels Therapeutics. Would you make a video about this company please? What's your opinion about Decibels Therapeutics?

[@julianmiranda297]

¿Que fármaco desarrollo esa empresa para la audición ? ¿Hay esperanza aún?

[@gb9557]

Dr. Is there a cure in clinical trails a the moment which can cure Hearing loss in future? What do you think? Which is the most hopefully trial? Thx

[@orange_turtle3412]

There are a lot. But none have the funding FX-322 had. We’ll have to wait for them to get the money to progress before we see anything else hit stage 2.

[@karwanduski8307]

This time he stopped taking this medicine completely​@@orange_turtle3412

[@ulkutuna]

@@orange_turtle3412 why no one funds hearing loss clinical trials is beyond me... there are millions of people with hearing loss but why isnt this seen as a problem that is important? Why are eye disorders seen important and have many options(operations etc)but not hearing loss?

[@hakanay2891]

Good news for hearing aid companies

[@MohamedAlshareeff]

😂

[@MohamedAlshareeff]

هم يحاربون هذه العلاجات

[@kaylasmusic]

Nah they’re gonna go out of business because the technology has gotten awful

[@Louie200Seven]

What questions should I ask a nearby clinic if I live hours away from a clinic that follows best practices?

[@DrCliffAuD]

I would ask them the fastest route to take when driving to the best practice clinic.

[@eddietulane6594]

"found and then lost" is an interesting way to say they lied about their study

[@humanexpert2088]

Do you think the Silicon bank crisis and this have something in common?

[@kasforai]

I''ve tics so loud noise causing both of my ears got messed up

[@LocutusH81]

Is there something in development for people with hearing loss caused by an Acoustic Neuroma?

[@DrCliffAuD]

No

[@orange_turtle3412]

Its a very similar situation to cancer. The best “cure” we have right now is radiation therapy.

[@jackburton307]

There still are others like NHPN 1010. Don't just push the hearing aid narrative!

[@markleben2347]

Can you amaige if there was a cure for deaf and hard of hearing people to hear again without aids to were every hearing specialist will be out of business

[@FurkanTopal]

6:30 who are they? where they got treated?

[@DAViDD767]

Greed is good they said, but I doubt it, because if it was, there will be world peace and harmony, so I guess we as humans will have to suffer some more.

[@DrCliffAuD]

You do realize that a cure would be worth Billions of dollars right?

[@Aviorrok]

The cure will be ready in 5-15 years more and more people have hearing loss the world need it

[@ulkutuna]

Why dont we need it now? There are already millions of people suffering from hearing loss. What will change in 5 years? Are we invisible?

[@Aviorrok]

@@ulkutuna science is difficult regrow hair cells is very difficult wait few years that’s all if you want to angry enjoy with that

[@julianmiranda297]

Para mi que apenas tengo 20 años no tiene sentido esperar tanto, toda mi juventud sse lo llevará esta enfermedad.

[@ceozyamerz4778]

Why not replace the hearing hair cells

[@erock3737]

Are there low EMF hearing aid available?

[@madridinfinite5297]

Can you make a video about your toughts on the Australian company which had a succes trials on curing hearing loss and tinnitus ?

[@ulkutuna]

Which conpany is that?

[@camefromnothingcfnentertai4559]

Hi sir hoping a reply and solution it's regarding tinnitus, am just feel scared and confused even to cross a road also losing balance in sometimes. Is there any solutions

[@orange_turtle3412]

Get it looked at by a doctor. Not all tinnitus is permanent. Sometimes (like in my case) its just a bad infection or something. There may even be a way to get rid of it!

[@E1N101]

Was your T in both ears?

[@camefromnothingcfnentertai4559]

It's on one ear only on mri there was this " Grade 1 vascular compression on left vestibular cochlear nerve by the AICA noted.

[@jamiebancroft706]

I want a cure for my reverse slope hearing loss.

[@chintangajjar846]

Any update on spi-1005??

[@susanharay2239]

I lost a bunch of money when I invested in Frequency Therapeutics!!

[@MrZbest1966]

sad what a disappointment

[@gng11]

Does anyone want to crowdfund and continue this project?

[@ahmadm.nawafleh2423]

Let me tell you something, when we talk about hearing loss treatment, we are talking about an idea that worths hundreds of billions dollars. So, it is not so easy to reach that goal, but scientists will find it out in future. (Maybe after 15-20 years or more 😅😢)

[@amertaemaa6559]

Dear Dr Cliff what is your opinion about that sad news? Do you think hearing industry stopped them(frequency therapeutic) you always give agood informative news about hearing aid and hearing researches but you didn't tell us what vitamins or minerals or any kind of hearing supplements keep SNHL at the same level!!!!! PLZZZZZ ADIVCE US🙏

[@DrCliffAuD]

Hearing industry had no impact on this. The drugs just didn't work. We need Elon Musk to search for the cure.

[@amertaemaa6559]

@Doctor Cliff, AuD 😁😁😁what about vitamins and minerals that can stopped to go worse

[@meric12131415]

​@@DrCliffAuD 🤣 eventually I mean maybe bill gates will probably find that first or and this is wishful thinking a device that taps into certain parts of your brain to target certain issues like hearing loss possibly a microchip perhaps?

[@juancarlosnavas1]

@@DrCliffAuD The only way would be if Elon musk had a bad case of Tinnitus and Hyperacusis. I am not saying that is my wish.

[@thomasallen647]

Billy wants most humans taking dirt naps

[@venkataswamyparagati9548]

You are speaking in high speed. Yo6 remember the viewers are people with hearing problems. You speak slowly explaining the remedies.

[@karwanduski8307]

This time he stopped taking this medicine completely

[@MoonsXOXOXO]

Better to do videos on acceptance especially for parents

[@gb9557]

Elon Musk is a good idea!!! So Write them.

[@lenkasuresh1460]

What is the idea

[@CharlesSneed-c3l]

I think this drug works and there was some other reason for the trial failure.

[@jojo-js9dt]

Hearing aid and cochlear implant industry?

[@CharlesSneed-c3l]

@@jojo-js9dt I think it is fair to speculate that.

[@sfrink1425]

Cliff, you bad boy. How dare you give people hope, LOL. Ultimately, it's still up to the individual to take responsibility for their own healthcare, not necessarily just listening to information found on the internet. While there was some promise from Frequency Therapeutics, waiting for the miracle cure and ignoring the solutions currently available is a mistake, as you indicated towards the end of the video. Hearing aids and other current solutions (cochlear implants, surgical solutions for conductive losses) can still provide some help, even if they aren't a full-blown cure. People should go with what DOES work for now while waiting and hoping for a real cure, and they should wait until it's available.

[@meric12131415]

🤣 aye it's a conundrum

[@venkataswamyparagati9548]

Useless talk. Wasting viewers valuable time.

[@CheffyJeffy76]

Come on man. They were told to shut it down. Blackrock and Vanguard own the most shares. Hearing Aid industry is way to profitable and you sell them right?

[@ASBOAIRLINES]

Wow, so this is really a thing :( which I was sensing earlier but didn’t even want to check… fucking hearing aids manufacturing lobby :( this has me speechless and is leaving me hopeless

[@naelbeno6249]

They don’t want 😉

[@gelo_san1744]

dude they snuffed it so bad 🥲