Diet Soda Causes Fatty Liver Disease? | Educational Video | Biolayne

Citations:
pubmed.ncbi.nlm.nih.gov/37985...
pubmed.ncbi.nlm.nih.gov/31697...
pubmed.ncbi.nlm.nih.gov/29760...
pubmed.ncbi.nlm.nih.gov/32216...
pubmed.ncbi.nlm.nih.gov/37794...
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[@paulmarino8810]

So 2 big macs and 2 lrg fries with a diet soda.....and we're blaming the diet soda for fatty liver disease? Mmmmmkay.

[@DILFDylF]

I feel attacked

[@jasonhsu4711]

But diet pop has the word "diet" in its name! Therefore, diet pop is a mysterious magical antidote! :)

[@criticalthinker7822]

mmmmmmkayyy😂😂

[@spgtenor]

The bigger question is, why bother? Diet soda tastes awful!

[@jasonhsu4711]

@@spgtenor I fully agree! Even if diet soda pop were healthy, I'd still refuse to drink it.

[@AlanChunkyMunky]

id buy a "HUMAN, RANDOMIZED, CONTROLL TRIALLLS!" gym tank top

[@OfficialBeeswax]

Yes

[@Christian-xf5ke]

This is an impeccable idea

[@AislingDonohoe]

Also a “RANDOMISED” one for us Europeans 😅

[@ivoPelayo]

Hell yeah!

[@mrsjuanitabarnard]

💯💯💯💯💯

[@dyderich]

If I avoided everything people on the internet told me to, I couldn't even breath let alone eat or drink.

[@keithseymour9316]

Honestly... thank goodness we have Layne.

[@dionthomidis]

Who else is drinking a diet soda while watching this🙋‍♂️🙋‍♂️🙋‍♂️

[@qwietstormz]

Strawberries and Cream Dr Pepper Zero...

[@ThingsYoudontwanttohear]

You can take my artificial sweetner from my cold dead overly sweet hands!😬

[@lindakirker5904]

How about a tee shirt that says, What the Fitness! I would buy that one too.

[@jonshick5661]

Well done as always!

[@johantansir-nt4ep]

Thank you for keeping being unbiased 👍

[@melissarandall2617]

Thank you Dr Layne! 😆

[@InnerStrengthVarun]

What a surpise, the real monster under the bed isn't diet soda

[@Budgargy]

Then why is basically everyone consuming them overweight. If they cause weightloss they should be lean by now.

[@CW-ty4ty]

​@Budgargy they don't cause weight loss, but people looking to lose weight and cut out sugar or excess calories can use diet soda as a replacement drink. If you're still over consuming calories after switching it doesn't matter if you switch to diet soda because you most likely wouldn't lose weight except for a few circumstances.

[@Budgargy]

@@CW-ty4ty Then the mass replacement of a supposed negative with something neutral should result in a positive effect in regards to weight loss over the long term but it obviously hasn't. If the only variable is overconsumption of calories and not hormones/metabolism why are the artificial sweetener consumers consuming more.

[@fredrikfahre9017]

@@Budgargy Dude, just watch the video. He answers that exact question.

[@_JustARandomDude]

​@@Budgargybecause those people eat like shit. You can drink water all your life but if you eat like shit you'll be fat it's not matter of diet soda or not.

[@DMRYeti]

I was nerding out waiting for you to delve into mediating vs. moderating variables! Love your content. I’m here for the debunking of bullshit and over interpretation of data.

[@geoffreyjohnston4816]

Great video, o stayed away from diet soda totally for years because of old science and poor info. Since I started watching yours and other science based nutrition influencers, I no longer fear artificial sweeteners. Thank you

[@phlew2010]

its def not good for you but do you

[@hioxd]

Based on?​@@phlew2010

[@BMGipe45]

​@@phlew2010 in absurdly high doses (maybe 50 cans a day for years), you might be right. Normal doses? Like 1-3 cans a day? Yeah, no. There's arguably zero data that shows diet soda is bad for you.

[@StraightEdgeJunkie]

@@phlew2010 You people need to stop just saying stuff. I'm getting so tired of it. You make such a strong claim, please cite evidence. Don't have evidence? Don't make the claim.

[@noggintube]

@@phlew2010 Water is bad for you if you have too much. As has been said many many times on scientific based channels, the dosage makes the poison.

[@TheBlakeLeroy]

I've gotta say... I love your pronunciation and enunciation

[@nicorellius]

Layne nailed it on this one with data, not feelings...

[@brentismaximus]

Your character impersonation sounds more like homestar runner than disney...but definitely funny. Good Staff as always.

[@videogazer801]

Damn, Layne broke it down and straightened this sh*t out.

[@cindywalden8340]

Yessss! T-shirt please!!

[@BornToRun.]

TY!

[@nickfoolery]

Oh my god, yes, please make a t-shirt that says "human randomized control trials"!

[@paddy3622]

this is the type of study thomas delauer would spend 15 minutes validating.

[@BigDog-tn8re]

Then contradicting it in another video

[@MrGhettoblastin]

Does he still do all the bs content like Fung and others? Blocked that channel ages ago

[@DrAJ_LatinAmerica]

Thomas would use it to spend 15 min. to sell you food delivery to your home and supplements

[@paddy3622]

@@BigDog-tn8re so true.

[@Themata]

​@@MrGhettoblastinsame, I had to block it, so much click bait, advertising, and unreliable information

[@allisonfalin8854]

Working in GI and managing MASLD, Cirrhosis etc patients, weight loss is what reverses the liver inflammation, which leads to fibrosis and liver failure. Unfortunately, it appears that alcohol related liver disease is again surpassing MASLD in some cases, specifically women. The number of people I see shocked to find they have cirrhosis after years of diabetes and or fatty liver disease is surprisingly high. Reduce saturated fats, lose the weight and get the sugars under control. Easier said than done, but it beats the heck out of a liver transplant.

[@ThePowerMoves]

Random assignment doesn't mean that the groups are equal (chance imbalances). I think it's worth reminding that. Great vid as usual

[@glennrobin3141]

Comment cause I love your stuff and I might get to see it more often

[@1ExplosionsHurt]

Yes

[@thekingtauros]

I use diet soda for my cocktails. I also have a slightly fatty liver. I think we can guess what has a bigger effect on fatty liver and what I cut to help alleviate it.

[@karynstouffer3562]

Diet soda is one factor for my 30 lb weight loss over the last 7 months. One other factor was greatly reducing carb intake. Put me on the list for one of those shirts!

[@LAP02]

Layne.... This.... I love you more!❤

[@andrewzach1921]

Comment Fooooorrrrrr the Algorithm.

[@PattiAnn507]

Yipee!!! Diet soda puts me in my happy place.

[@emotionalignition]

Where the t shirts at?

[@jadkarnoub469]

Can’t wait for that shirt to come out 😂

[@wellnesssecrets2014]

Create right conditions for good health

[@gregorygreene1940]

Yeah, I'm going to continue to drink zero soda. Somehow I think those 39g of sugar in a regular soda are not good for NAFLD.

[@shoulung6203]

The way it went for me was NASLD, obesity, pre diabetes, then drinking Coke Zero. What I’d like to see is a study on whether NASLD creates/accelerates obesity.

[@gregorygreene1940]

I went obesity, pre diabetes, T2, NFLD. As a person who has struggled with weight their whole life I think you initially drink diet soda so you can eat more of other things. Over time you realize that it's not working out well for you. Eventually you succumb to the laws of thermodynamics. If you want to lose weight you will have to be in a calorie deficit. There is simply no way around it.

[@shantanusapru]

"Mediating role"?! What they mean is "confounder/confounding variable"!!

[@2adamast]

Randomized trial on fatty liver, the randomized group taking full sodas is bound to be impacted by their extra 2800 kcal/week intake. And besides that it probably takes at least a year to see significant fatty liver development as diabetes is not a 10 weeks affair. But I get it randomized is top notch.

[@jacobdebernardi4385]

That impersonation got me fuckin rolling

[@OfficialBeeswax]

I feel like I've seen this video before

[@demoncorejunior]

i wish there were studies on what factors make people more likely to consistently consider and use artificial sweeteners. i have known many people who use them and they span the spectrum from obese to bodybuilder. all the people i know who enjoy artificial sweeteners are engaging in what i would not describe as “the most healthy” nutritional approach, especially the body builders! is the psychology of craving sugar something that can be addressed outside of glucose/insulin reaction studies? i view replacement sugars as a symptom of an otherwise lacking diet rather than a cause of health problems

[@ronswaff7109]

If I drink it while fasting will it still give me AFIB?

[@p7reston777]

FTA ( for the algorithm) 🔥💯❤️

[@MSJARELA]

It’s the diet soda! Definitely not weekend binge drinking! Check!

[@johnnymiles8694]

diet soda is why I am fat. Finally, it is not my fault

[@boneTHUGS111]

i wanna know if diet sodas are bad for the brain as everything ive read says they are

[@robertthompson5501]

When dining out I add a scoop of EAA to my water with lemon.

[@martine5716]

I want that tshirt❣️

[@user-ef2gw5yr2j]

can you make a video on if high protein diets are safe for fatty liver disease

[@2adamast]

Is safe as you need a functional liver to maintain high protein

[@wigletron2846]

I'd be interested in that too. I was eating 300g of protein during a show prep and had elevated liver enzymes after the show.

[@defeqel6537]

@@wigletron2846 I assume you were excessively low body fat too, which wreaks havoc in your body in all sorts of ways (and yes, excess protein is harmful without fat, it's basically rabbit starvation)

[@Ryan_DeWitt]

I drink a buttload for years now of diet soda. Recently had a test done on my liver and it was at the very bottom end of being fatty. In other words, really good in terms of being fatty. Just anecdotal, but my personal experience.

[@DrAJ_LatinAmerica]

Possibly for any PED use? Also from some supplements, especially any supplements exposed to heavy metals and from some herbs / spices. To get big, you must eat big. Over consumption of carbs? Many factors and variables that can present as fatty liver.

[@baraabinhomran528]

For the algorithm!!

[@NattyMuscleDude]

dr layne is MASLD cureable or will weightloss reverse MASLD?

[@videogazer801]

It’s not curable. It’s very bad

[@videogazer801]

In my opinion, I stay away from drinking all those drinks with like 20 ingredients that I can’t pronounce. Nothing is really curable by itself, I feel it can recover a great bit with treatment, but it would always have some amount of permanent scarring.

[@DrTomMD]

Yep. Classic case of reverse causality.

[@Simon-talks]

I take bourbon for my liver health

[@Redbloodroadrunner]

I have a genetic predisposition to a fatty liver, and my weight is what’s gonna kill me long before diet sodas, I sure didn’t switch from regular soda to diet just for the flavor 😂

[@john-lukepickarde7382]

I was literally drinking diet soda when I clicked on this video, and before it started, I had already guessed that the results are most likely due to overweight people drinking diet soda than the diet soda itself causing the fatty liver. Why do studies like these even get funded?

[@bigdbag]

Fat researchers huffing hopium

[@seamussullivan2218]

FTA!!!

[@DarkTypeWriter]

"MASLD Talk!"

[@christrejbal3787]

FOR AL GORE-RHYTHM

[@janem3575]

me liver masld before I started the diet sodas!

[@gokukakarot1855]

For the algorithm

[@marcdaniels9079]

I had a colleague who travelled a lot and ate steak and chips virtually every night with copious quantities of alcohol. He developed FLD…. Never saw him drink a Diet Coke though 😮😅

[@JamesSerapio]

For Al Gore's Rhythm!

[@joaorocha144]

Diet soda > water

[@AndrewBrownK]

Lawyers rubbing their hands together and plotting their next attack angle on diet soda

[@Karol___]

FTA

[@croissantsaregreat856]

fta

[@kickhuggy]

I don’t think anyone in Hercules sounded like that bro

[@JDell913]

FTA!!

[@Dan14833]

I disagree, it is not even interesting data. It’s unsurprising, obvious data that and the summary is worded in a way to grab a headline. Basically, they demonstrated that population data indicates that diet soda does not have a negative effect on fatty liver disease and the summary leaves open the opposite conclusion.😂

[@R2RHIker4]

Algorithms 😅

[@ArvilVonPoney]

Alternative video title: MASLD causes diet soda consumption ? | Educational Video | Biolayne

[@robclark6223]

Fta

[@Joseph1NJ]

_Welcome to the artificial sweetener channel_

[@ashdgee]

😂😂

[@AndrewBrownK]

Gotta love the HUUUMANN RANDOMIZED CONTROL trials!

[@aaronbailey9454]

FTA!!!!

[@nattyfatty6.0]

4:19 It's not even "trying". Had they not been consuming diet sodas, they'd be even fatter, because their caloric intake would've been greater. So it was successful, just not at the granularity of "obese vs not-obese" that people are categorizing things

[@defeqel6537]

not necessarily, just depends on how diet vs regular soda affects their satiety

[@Bejkomut]

I know the drill.

[@4u2nv503]

FtA

[@turbomanmechachrist]

Sadly not many P-Value stronger than 0,05 in this study. Too many confounders to be interesting on its own merit as well.

[@MyChilepepper]

Some people like to buy a truckload of them just to make the ceos richer

[@sercan272727]

always wondered cant they find like 50-100 people who actually understand the science and variables and use them as the subject for these studies instead of random people who can be getting fatty liver for any reason along with diet sodas.

[@StraightEdgeJunkie]

These studies are done to benefit average people, so it makes sense to study average people.

[@Anaelise84]

Watching this while drinking my sugar free 7-Up

[@brucejensen3081]

It's what is in the heart that matters. They want to consume crap.

[@BigDog-tn8re]

Thank god. After last video I thought it was going to say it causes anal bleeding

[@RG-yz8ov]

I asked meta Ai or should i say meta Dumb intelligence. Does diet soda increase fatty liver. Ai's reply Diet soda consumption is associated with an increased risk of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD) ¹ ² ³ ⁴. The key findings are as follows ¹ ² ³ ⁴: - Diet soda consumption is linked to an increased risk of MASLD, a condition in which there is too much fat in the liver. - The risk of MASLD increases with the frequency of diet soda consumption. - The association between diet soda consumption and MASLD is partly explained by body mass index (BMI). - The artificial sweeteners used in diet sodas may contribute to an increased risk of MASLD by promoting insulin resistance and glucose intolerance. - Diet soda consumption is also associated with an increased risk of other health problems, such as type 2 diabetes, high blood pressure, and vascular events.

[@IP.1]

You and Dr Mike of RP, need to do a roast of influencers. They’re like weeds, it’s hard to see past their BS. No wonder we get confused.

[@michalgrzywaczewski5194]

Dear Norton, i guess you should ask for likes, AFTER video not before

[@marcdaniels9079]

FTA 😅

[@Torviticus]

I hope I never hear MASLD spoken again.

[@nattyfatty6.0]

I will keep calling it NAFLD, because MASLD sounds dumb

[@chetlyp]

Was it obesity or the diet soda? It's the obesity, lol. Speaking as a physician for the last 24 years, it's the obesity. I see it in patients, I see it in friends and I see it in family. I don't need to watch anymore of this video.

[@MisterHui]

That's only something Big Fat wants you to think! Don't be fooled! I was fooled once, twice and three or more times so I should know something about bring fooled and this smells, tastes and looks like foolery!

[@Mrbluefire95]

Another very obvious outcome lol

[@johndoiron9615]

This is why I only drink regular soda. I'm not taking any chances.

[@Bountyhunter411]

Did you watch the video?

[@Mrbluefire95]

It has to be embarrassing to be this stupid

[@johndoiron9615]

@@Bountyhunter411I've heard him talk about it before. I have no problem with diet soda, but I drink soda because of the sugar. I was making a joke.

[@Themata]

Smort 👌

[@Budgargy]

Artificial sweeteners have existed for long enough, everyone consuming them should be lean by now if sugar actually made you fat.

[@StraightEdgeJunkie]

I agree that sugar doesn't "make you fat" since what makes you fat is just excess calories, regardless of source, but the argument itself flawed; people can drink diet soda and still eat a ton of calories from sugary foods, and get fat. So, drinking diet soda doesn't "make you lean" - it can help you get there if you use it to replace other sources of calories. But if you add it on top of too many calories, you're still getting too many calories. But yes: sugar doesn't "make you fat". And I'm just being pedantic.

[@Budgargy]

@@StraightEdgeJunkie Then if the only variable is calories and not hormones/metabolism obesity wouldn't be higher than ever due to the mass replacement of sugar (calories) with artificial sweeteners (no calories).

[@StraightEdgeJunkie]

@@Budgargy Sugar is not the only source of calories. What are you on about?

[@Budgargy]

@@StraightEdgeJunkie Exactly! Carbohydrate (4 calories per gram, under 75% efficacy for fat storage), fat (9 calories per gram, 99% efficacy for fat storage). Sugar sweetened liquids satiate, artificially sweetened ones don't and change preference to fat consumption. Water does neither. That is the primary mechanism for the obesegenic effect.

[@StraightEdgeJunkie]

@@Budgargy Eh. It's true that most of the fat we store is from the fat we eat. But what dictates how much overall fat we store ultimately comes down to energy balance. You're correct in saying that there are differences in how many calories there are available to potentially be stored in different foods - although sugar is actually more available than some other carbohdyrates, it's not the same rules for all carbs - but because it comes down to energy balance, you can eat, just work with me here, 200g of fat, totaling up to 1,800 calories, and if you expend 2,000 calories, you will store none of it. But if you eat 200 grams of carbs, now you will store 600 calories of the fat. Carbs generally are not directly stored as fat like dietary fat is, but they still play a role in working as a caloric cushion for the fat. And if you overconsume calories, but it's all from something like soda, with no fat, de novo lipogenesis takes over and you will store the net excess. You can't game calories in, calories out.

[@paolacedeno9365]

😂😂😂😂

[@tonybernard4444]

Conclusion: we got the results we wanted, despite the fact that our selected cause is statistically insignificant. These bozos need to be kicked out of the science club.

[@TigerShark316]

Great video! Actually, I don’t know yet. I just wanted to be the first comment. But I’m sure it will still be great because all of them are.

[@TheYangoable]

[@timgazsy666]

Who likes or drinks more diet soda trump or Biden? That’s where I’ll draw my line of allegiance!