Lipid Transport (pt. 2)

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
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Opinions are entirely my own.

[@rajarammanoharan791]

With B48 it enters the Blood stream With C2 it acts on the Capillary endothelium of muscle &fats With E it Enters into the liver

[@ChrisBranleh]

I remember Apo B48 = Chlymicrons as, "I just ate, so I have B48" (ate = 8) bc Chylomicrons are only present following dietary Triglyceride consumption.

[@saawanpatel7413]

Bro I can't believe you are providing such quality content for free! You are a life saver and all the future physicians are in your debt. God bless you man.

[@joeamrine7450]

I'll forsure make sure to tell all my friends at my med school about your videos great videos man

[@americanlacost4888]

i dont believe that 3 people disliked this ig they are the teacher who explains everyting in a complex fucking way

[@geneveweil2938]

Seriously thank you! You’re a godsend

[@danielcastilo1840]

Dr . D , God bless you 👍. Thanks for the great videos,

[@lisagonzalez2902]

Omg, this was a fantastic way to break it down. And the mnemonics for lipid transports are way too good. I've written all of them down on my First Aid.

[@yashpatel9369]

Whooaoa

[@rameshprasadupadhayay6447]

its great dude , love the way you explain

[@motivationpilldaily]

Thank you for this beautiful video! You made it really easy to understand and remember.

[@Habe111]

Phenomenal as always, thank you dirty

[@naginakhan1ify]

All concepts are clear. Thank you!!

[@arjang53]

Thank you for the great videos, :)

[@chestnut1064]

After multiple attempts to learn, I’m beginning to have a grasp of it finally😊thanks a thousand times

[@soniasingh97]

Love this explanation

[@mamoonbilal5983]

What an explanation, great work🙀

[@alevelsdemystified3410]

Sir, please make a video on glyco-lipid metabolism. Your videos are so awesome!

[@swetaruparel3233]

Very very very helpful !!! 👍👍

[@tanyaratnani5509]

thanks man I can’t thank you enough

[@tameem10984]

These are some top videos bro 👍🏻

[@taiwanusmlenote5067]

hi dirty thank you for all the videos. I wonder if it is possible to integrate this video to lipid lowering drugs? because drugs are also highly tested. could you make a video about lipid lowering drugs as well? thank you so much!

[@miguellinares8260]

this is SO GOOD

[@raymondvaldepenas5863]

This is really helpful, thanks☺

[@joeamrine7450]

What are you man where do you get all these incredible mnemonics this is unreal

[@Umir445566]

He's extraterrestrial.

[@muneebtakesmedicine]

As he once said, he's a humanized bot sent to Earth to teach us medicine in a 'fun' way :p

[@maskman8278]

​@@Umir445566 😂😂

[@sitha4441]

Thank you.

[@selinasogweje5188]

You are my friend dirty medicine that for making me understand this difficult subject on lipid transport. I love uuu

[@etwl]

those 4 people disliked this because they thought the thumbs-down button is download

[@muneebtakesmedicine]

DAMN XD

[@kayallen7603]

B48 = transports into lymphatic system, HDL adds C2 and E, in the blood circulation. C2 activates LPL to release the triglycerides for storage E then then break them into remnants for recycling. The chylomicron goes into the liver where it will be recycled.

[@xafjr4991]

Nice video. Tks a lot

[@jameyatesmauriat6116]

Hi Doctor Are there any videos about Malate Aspartate shuttle or glycerol phosphate shuttle and do these pathways come in USMLE or never?

[@lovingtheunlovable]

I dont get why insulin cause breakdown of triglycerides to form fatty acids i though this happen by glucagon or something during starvation... activating lipase shouldnt insulin promote triglycerides formation due to excess glucose in blood

[@JOAT22]

GOAT stuff 🙌🙌

[@Zayrgilles]

Mate. Did the HDL Arrive on a magic carpet?

[@ThienTruong-iy5ix]

omg dirty medicine how are you so good at this..

[@aliiraq9655]

Cool .. thanks ..

[@MedicinePearl]

Very nicely described

[@EnergyDiscoveries]

doesn't Insulin 'drive' the fatty acids into the cells rather than 'break down' triglycerides into fatty acids? and I think ApoE is the key that allows the remnant Chylo. to "Enter" into the liver.

[@amindonardi4470]

enterocytes abosrb fatty acids and cholestrol, packaging them into triacylglycerols inside chylomicrons, then they circulate the blood until they go to endothelial cells of capillaries neighbouring other tissues. They are converted back to fatty acids and other substances that can easily pass through the membrane there by LPL and there they are either used for more energy or converted to triacylglycerol by combining it with glycerol. insulin drives LPL, while glucagon drives HSL. Now why doesn't the human body just directly send triacylglycerols through the membrane....i have no clue, guessing it is too big.

[@VVerrenTT]

thx

[@irina-mariapalaghia8506]

im starting to believe that the bomber is the exact reason why they named apob48 like that :0

[@mehakrubab2727]

Weldone

[@inaszahidah7557]

Hello, can I get some screenshots of your illustrations for my presentation in my class? The illustrations you made are so easily understandable. You made it very clear thank you. Of course, I'll put the link to your channel for the source

[@DirtyMedicine]

feel free

[@stevebradford3939]

u have simpliefied this so much. am watching this while reading fa and its such a cluster fuck. THANK YOU SIRRRRR.

[@GingerWaters]

Chylomicrons? What is that? Chylo=juice micro=micro?

[@jansamuelc.jardenico8094]

What reference do you use?

[@DirtyMedicine]

usually primary literature journals and databases that contain them

[@rmu1486]

❤️❤️

[@applush23]

Please make more videos n

[@mahnoorbaloch3341]

Can we please have part 3 lipid transport sir I am in dire need of that exam soon

[@DirtyMedicine]

kzbin.info/www/bejne/lai7iH9un86XgpY

[@nathalyalarcon9394]

I love you

[@xcast1]

Good vids, though a little bit too much of repetitions. (I'd rather like to get the whole picture quick, then potentially re-watch it)

[@kevinmaldonado5750]

8:25 threw me in for a loop man, wasted like 20 minutes trying to understand your whole explanation cause your're not wrong but you're also not entirely right either lol let me explain: You say that in type 1 DM you are unable to store fats because insulin mediates the breakdown of fatty acids and storage of said fatty acids which technically is like 10% of whats really going on. The true cause of the weight loss is the unnopposed action of glucagon which activates HSL within the adipocytes, and this in turn metabolizes stored fatty acids for energy production since these patients are unable to yield energy from the glucose . Like i said you're not wrong your wording is just confusing. Great video though honestly, I wouldnt have made it through these first 2 years of med school without some dirty little medicine, love your content my guy!

[@olaolu10]

This shit sucks, thanks