DNA replication in eukaryotes 4 | Replication termination and telomerase

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@@shomusbiologyofficial sir i have a question.. Sir why not AC is connected with first TG..why it attached with next TG

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[@shivalig7007]

Sir just clear one thing 9:57 the sequence TGGGGTTG present on dna strand is provided by telomerase or it was already present on parental dna strand???

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thank you very much sir ! sir i understood dna replication in eukaryotic after watched your channel .you describe clearly each and every steps very easily so got it everyone quickly and simply i also got it ..so thats great thx again

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brilliant way to explain the complicated process in such a simple manner thanx shomu sir...god bless you :-)

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give this man a raise..

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U have explained in a great way the end replication problem.. 😃

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You explained in a very simple way,my Ph.D professor took 1:30 hour but failed to convey the point.

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[@HaroonIqbalB]

The tandem repeats of telomere is TTAGGG.

[@Vasílissa2024]

Sir you explained that DNA polymerase alpha replaces the RNA primers in the lagging strand but in your previous video you explained it to be the work of DNA polymerase delta and Fen

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Very good explanation

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Thank you sir..finaly my concept about DNA replication is clear

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[@hafsahassam8828]

very well explained. I just have one question, what happens to the complementary daughter strand at the end of replication. does it increase in length as well?

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very nice explanation

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Thanks for the explanation! well done! Could you have one made for TRAP Assay-Telomeric Repeat Amplification Protocol- please? Much thanks! Cheers from Germany

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Please explain on genetics basic techniques

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Understood completely 😊

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Very helpful vdo sir thanks a lot to make me clear this section ..

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Crystal clear! Well done😄

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Sir, you didnot explain that alpha DNA polymerase and primase will use this parent DNA strand(extended by telomerase) and synthesizes remaining part of lagging strand

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[@Reshma-tc5ho]

Sir, does the telomerase act at the end of the leading strand in the same way?

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[@poojakolsur8905]

Sir u said DNA polymerase enzyme polymerase only from 5'-3' direction but in this u said 3'-5'....plz clear me this sir...

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It would be nice if you mention the recognition sequences also.

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Hello sir... I watch many of your videos... you are saviors.. sir... I have a request can you give any hand written or any kind of notes which help us for the examination ???

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You can buy our study material package to get it in book form

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👍

[@Bignutterfly]

I thought the leading strand was 5'-3' and the lagging strand was 3- to 5', as DNA polymerase works in a 5'- 3' direction

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Thank you so much sir... I request you to make video classes on how to clear ( I mean , the portions to be covered) the entrance exam for MSc. Biotechnology

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nice video sir Meri concept clear ho gayi

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hey chandana I have a small doubt yar as I'm a MSc biotechnology student I completed my 1st semester too I have a doubt is biotechnology have a scope to get jobs now a days pls yar clear my doubt

[@gowthamin7009]

chandana .r hey chandana i have a small doubt yar as I'm a MSc biotechnology student I completed my 1st semester too I have doubt that is biotechnology have any scope to get jobs now a days pls yar pls clarify my doubt

[@thebiologybox2959]

Thank u sir for this concept regarding Replication

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+Falguni Falgujhara you're

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+Falguni Falgujhara you're welcome

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Thnx sir fr clearing all my doubts..

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[@sudhanvaddixit7141]

What bad can happen if the DNA replication does not occur at telomeres of chromosome ? List any 5 Changes.

[@kid.karthik2955]

@7:09 sir u have mentioned that DNA polymerase alpha will be used to fill the gap but in the last video u have mentioned that DNA polymerase delta will be used to fill the gap.. so which one is right??.-.

[@enmanuelrosario9243]

delta

[@PriyaSingh-nk7mt]

Same issue..

[@ranjitsbioconcept6264]

It most be alpha ,,I think bcs,Delta involve in new strand synthesis

[@asmamajid7816]

It's alpha which fills gaps

[@doctorshanky2470]

No way it's delta

[@illuminatiscientists3145]

You didn't say that Dna pol alpha extends the telomeric complementary sequence in the daughter strand.

[@humanawaz8552]

Thanku sir for this concept

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Thanks Sir!❤

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[@abhipsapathak5802]

The gap in the lagging strand is filled by delta polymerase or alpha polymerase?

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Thanks for the explanation!

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Thank you

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[@shwetashinde5831]

Awesome explanation. Bt i have 1 doubt. Telomerease stretches parent DNA strand, but what about newly synthesize strand?? Will that lost gene at the end??

[@mubashramughal8794]

Plz make a detailed video upon Dna topology ... plzzz

[@creations3026]

Can u plz upload videos on these topics. DNA sequencing, splicing,mutation central dogma and DNA repair. PCR technique. If can plz upload them in 2 to 3days. Thanks

[@shomusbiologyofficial]

+Angel Baloch you can find them in my channel. It's already there

[@unziping_heaven]

I have a problem After the addition of telomerase enzyme ,parental DNA is stretching in the forward direction because it has free oh grp attached. But in the case of daughter or newly synthesized DNA strand there is no free OH grp. , Then how will it synthesize further as DNA polymerase can't do this alone. What is helping the daughter DNA to stretch forward and when it will get terminated?

[@HaroonIqbalB]

As for the termination needs teleomerase enzyme, in daughter DNA, it plays the same role as in parent DNA.

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Sir thanks a lot ..u are such a brilliant teacher...God bless u.

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Shehnila asghar

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Yes

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Superb

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