EARD 2023 Panel Discussion: Is Aging Truly Reversible?

Dr. Oliver Medvedik, Dr. Aubrey de Grey, Dr. Peter Fedichev, Dr. Hanadie Yousef, Reason, and Dr. Hans Keirstead debate whether or not aging is truly reversible at the Longevity+DeSci Summit NYC (EARD 2023).
Summary
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Dr. Oliver Medvedik earned his Ph.D. at Harvard Medical School in the Biomedical and Biological Sciences program. Oliver is presently the Director of the Kanbar Center for Biomedical Engineering at The Cooper Union, where he carries out research on improving gene targeting in mammalian cells, enzymatic oligonucleotide synthesis, and other bioengineering projects with undergraduate and graduate students at the Albert Nerken School of Engineering. Dr. Medvedik is also the co-founder of the community biotechnology laboratory, Genspace, located in Brooklyn, where he continues to serve on its board of directors. In addition, Dr. Medvedik is also co-founder and vice-president of the non-profit organization LEAF (Life Extension Advocacy Foundation), where he serves on the board of directors.
➡️: / oliver-medvedik-4067016
Dr. Aubrey de Grey is a pillar of the longevity community. Dr. de Grey works on the development of medical innovations that can postpone all forms of age-related ill-health. His main focus is on rejuvenation: that is, the active repair of the various types of molecular and cellular damage which eventually cause age-related disease and disability, as opposed to the mere retardation of the accumulation of such damage. He is currently the President and Chief Scientific Officer of the Longevity Escape Velocity (LEV) Foundation.
➡️: www.levf.org
Dr. Peter Fedichev is an entrepreneur and scientist who co-founded three biotech companies: Quantum Pharmaceuticals, a drug discovery company, and Gero, a longevity startup, and GlyNeura, a biotech-pharma company aiming to cure Neurodegenerative Diseases. His scientific background lies in the fields of condensed matter physics, biophysics, and bioinformatics. His dream is to beat aging and experience life in space.
➡️: gero.ai
Dr. Handie Yousef is a leading expert on the biology of aging and mechanisms underlying tissue degeneration with over two decades of experience in biomedical research. In 2018, she launched Juvena Therapeutics, a venture-backed biotechnology company mapping the therapeutic potential of secreted proteins to develop biologics that prevent, reverse, and cure chronic, metabolic, and age-related diseases.
➡️: www.juvenather...
Reason is co-founder and CEO of Repair Biotechnologies. He has been an active angel investor in the longevity industry since its earliest days, with investments including Oisin Biotechnologies and Leucadia Therapeutics. He is a long-standing and well-connected patient advocate for aging research, involved in numerous fundraising and outreach initiatives conducted by organizations such as the Methuselah Foundation and SENS Research Foundation since the early 2000s. He is also the founder and writer of Fight Aging!, a noted news and commentary website in the biotechnology community.
➡️: www.repairbiot...
Dr. Hans Keirstead is an internationally known stem cell expert and has led therapy development for cancer, immune disorders, motor neuron diseases, spinal cord injury, and retinal diseases. He is the Chairman and CEO of AIVITA Biomedical. Dr. Keirstead's work in spinal cord injury earned him the distinction of being one of the 100 top scientists of the year in Discover Magazine. He was featured on 60 Minutes in a full segment covering his treatment for spinal cord injury. Dr. Keirstead and his research have also appeared in Newsweek, Inc. Magazine, WIRED, Esquire, The NY Times, TIME Magazine, Men’s Vogue, Science, and The American Spectator, amongst other national publications.
➡️: / hanskeirstead
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#longevity #EARD2023 #desci #decentralized #nft #biotechnology #biology #healthscience #livelonger #agingbackwards #lifespan #healthspan #research

[@sivaramaprasaddarsi2104]

Absolutely ,aging is reversible , molecular Regenerative therapy

[@SirTenenbaum]

As several panelists said, changes in aging amount to molecules being in the wrong place over time, so putting molecules back in the right place or removing the wrong molecules to make the molecular structure closer to a younger version is a form of reversing aging.

[@SilverFan21k]

Remarkable panel of so many cool people on stage at once.

[@SilverFan21k]

Great upload

[@andreialcaza]

I hope so

[@snorttroll4379]

Lifespan is more important. Health span can be improved later.

[@Montie-Adkins]

A nice talk. At 18 minutes dude says healthspan is way more important than lifespan. Never mind that large sign behind him that says lifespan. But, not to knock it too much, yes healthspan is important too.

[@Cybrix]

Well, healthspan leads to lifespan, so…

[@Basilisk2077]

Well, it is nice to live your miserably short life healthy, but that doesn't change the fact that it's still miserably short. The truth is, we have the lifespans of great apes, not the lifespan of a highly intelligent species, which is why we must fix that.

[@Basilisk2077]

And it's kind of stupid this word "healthspan" like we're going to be as healthy as a 30-year-old biologically and just suddenly die because we hit 90 chronologically.

[@Cybrix]

​@@Basilisk2077 It's a matter of framing. If the language used is "lifespan", the average normie thinks about being decrepit for an indefinitely long time. Using the word "healthspan" shifts the focus to the real goal: keeping people as healthy as they were when they were 30 or younger, and leveraging that good health to indefinitely extend their lives.

[@USAtoElsewhere]

A lot of bad health is tolerated. It's only when it's impossible to tolerate it that death must be given into. There is a big range of what can be tolerated. Many people want to give up at the point where they couldn't take care of themselves. That's not even necessarily the point where there would be discomfort to a significant extent. It sounds like a philosophy that makes some people unable to tolerate living.

[@roryblake7311]

Aging is, universally, decline triggered by parasitic action. Starvation is reversible. I'm doing it, people! The last guy on the right was closest...BTW.

[@johnstibal2131]

All that really needs to be done is to preserve the brain, directly or indirectly, everything else can be replaced. I'm wondering why so many people find this crazy? There is nothing sacred about your body...especially if you have a chronic disease etc.

[@USAtoElsewhere]

I do have the sense that every part of my body comes from my brain.

[@leiladasha]

aging is reversable we must fix DNA upgrade DNA

[@scotty-ek2ss]

The fact this is still being debated just shows we are nowhere near 😢

[@jordangreenwald1654]

Completely false . Debate is normal aubrey is working on rejuvenation as we speak

[@scotty-ek2ss]

@@jordangreenwald1654 in mice not humans 😢

[@Basilisk2077]

Depends what the role in AI will play in all of this. Superhuman intellegence that has endless data pipelines to sort through solves this a lot quicker. David Sinclair has said "the Wright Brothers are already flying" in regards to human rejuvation. I think we have 25 years tops.

[@ThanosDestroyeryearsago]

@@scotty-ek2ss Yeah, cause we test on mice before humans. We might be able to slow down aging significantly within our lifetime. True immortality is a whole other story. But consider we may live for a few centuries if this works. Then we’ll likely get there. Maybe even a form of Digital Immortality.

[@joeblow1748]

Are we debating fiksing a old car or are we debating unfiring a gun... Is biology a machinery or is it just a chemical change. A dandiline turns grey and we see old age but in nature its just part of an unstoppable prosess.

[@CamelxRavenNova2]

Transhumanism and biotech

[@fritagonia]

Go Aubrey de Grey! I hope we stop with abusive animal testing and instead start with humans. I think we should skip animal testing as much as possible. Especially when we are not animals anyway.

[@Pyriphlegeton]

But...we are animals.

[@fritagonia]

@@Pyriphlegeton well I mean non-human animals :)

[@Pyriphlegeton]

@@fritagonia Well yeah :D But animals we are. But I totally agree that we should reduce animal testing as far as anyhow possible.

[@mystikrebel1089]

yeh it is going to be but for now when i use photoshop

[@dougcane4059]

NO - diabetes can indeed be cured.

[@jimj2683]

Aubrey has a few more iq-points than the others there...

[@joemagicdeveloper]

Defining ageing, reversing ageing in mice... 🥱 Where are the therapies in humans?! Missed opportunity to talk about and point to clinics actually treating humans!

[@Pyriphlegeton]

Well, that's the biomed pipeline. First only animals.

[@joemagicdeveloper]

@@PyriphlegetonI understand that and that will benefit young people but for us old folks we need it now AND there is a lot happening now for humans. I'm yet to see a presentation/discussion on that! (plus tired of hearing this "pipeline" for the last 3 decades)

[@psychsnail]

​@@joemagicdevelopercouldn't have said it better myself

[@Rafa-pf7kz]

Acredito que a empresa turn.bio vá começar testes em humanos em 2025. Pesquise "turn.bio pipeline".