Exogenous Ketones with Dr. Ben Bikman

[@Controls_Tech_86]

As a construction worker, I learn something from every one of your videos. I just wish your field of science and your knowledge of it would be a textbook that all doctors would have to learn from before they can practice medicine.

[@Petunia-fl9lu]

they are supposed to refer to the specialists - hence they are generalists for that reason. they are meant to refer to dieticians if needed or endocrinologists if needed both who (should) have done biochemistry. its wonderful to be educated by someone who knows what they are talking about though. grateful as well.

[@cassieoz1702]

​​@Petunia-fl9lu dieticians are a big part of the problem it's also important to realise how much of this stuff is pretty recent understanding

[@curlyq9901]

Amen!

[@beNETiq_ru]

Learning that we get sick because of eating, yeah

[@Controls_Tech_86]

​@Petunia-fl9lu yes, but like a general contractor in construction, they have to know how all of the subtractors (specialists) work is supposed be done to identify if they are providing the owner (patient) a quality job ( fixing the underlying problem or diseases). In stead the medical system operates backasswards. The general physician hands the job off without knowing if the specialists are doing a quality job or not cause they don't understand the inner workings of the human metabolism, that's why it's failing to fix the problem, which is our health. So now the average person has to learn how their body operates without getting paid to do so or get a discount in health insurance for fixing ourselves, because the ones who make the most money don't know how. In my field if we under perform as bad we get fired.

[@rothelsbeth]

I've been using exogenous ketones! I've been following the Keto diet for 2.5 years and then switched to carnivore for the last 18 months. Dealing with advanced Osteoarthritis, I've found that ketones act as my pain reliever (better than painkillers). I've been keeping track of my ketone levels... Here's the interesting part - if my ketosis level drops below 1.5, I experience pain. However, after consuming ketones, an hour later the pain disappears and my levels are between 2.3 to 2.8. My GKI stays between 2.8 to 3.3 every day. It's truly remarkable! Thank you for all your fantastic videos.

[@dort5436]

Interesting N=1 for pain relief. Thank you

[@FreeKekistann]

Nice GKI (weird compliment 😂)

[@violinn5177]

Please, what are the exogenous ketones you use? Are they manipulated exogenous ketones? Thanks!

[@alines301]

Thanks for sharing!

[@zlmdragon.]

what exogenous ketones you use?

[@2makeshiftwings]

The more I listen to you the more I am so thankful I listen to you.

[@KetoneDean]

Amen. It makes my ground beef taste better

[@carlor.s.4742]

Dr. Bickman, I can't tell you how much I love these lectures! In fact I'm developing an addiction to them-LOL! I'm a retired clinical psychologist & have always had an insatiable thirst for knowledge. I spend my evenings watching lectures like these instead of watching bad movies. Although I've watched many interviews involving yourself, I didn't discover this channel until recently. Thank you so much for allowing me to go back to school & learn--the thing I most like to do!

[@benbikman]

Thanks for your kind comment.

[@donnatodd4119]

Your term “insatiable thirst for knowledge” is bang on to how I feel. I would rather learn than do anything else. My nose is always pointed down a rabbit hole of learning.

[@caitlin6151]

I started using exogenous ketones after hearing you talk about using them. I have one client that I visit every week for 6 hours and her house is made of candy. I drink the ketones and go through the whole visit without a horrible urge to eat the candy. I am so thankful I started listening to you.

[@plumbthumbs9584]

If there was a large cauldron in the kitchen, caution, your client might be a cannibal witch.

[@privatesuzie4071]

Do you use American ketone recommended by dr ?

[@carda5967]

Do you mind to share Which brand do you use?

[@stevehamilton9486]

@@plumbthumbs9584hahahaha

[@KirstiCheetahh]

Hi doc! I love your lessons! I have been eating keto/carnivore/cheesovore for 2 1/2 years to get rid of tendon pains, burning pain in my feet, fatty diarrhea. Great results! Woman, 54, LMHR, BMI 18.5 , play tennis fasted, retired, no stress. One problem persists: insomnia since early childhood, very active brain. It takes at least 2 hours to fall asleep and after a few hours of sleep I wake up and can not get back to sleep. I think I get low glycemia and high cortisol in the middle of the night. My liver seems slow in making glucose and ketones. Yesterday I took a teaspoon of MCT oil (70% C8 / 30% C10) in my yogurt at 8 pm (2 hours before bed). I have slept the whole night without waking up 😃 I hope this will continue.

[@ttiller3744]

Yes, eat fat before bed. Could even be butter.

[@johnk6578]

Yeah, sleep has been a lifetime issue for me as well. Also I’m an active 66 yo male and 1 year into my carnivore journey, so I’m still figuring things out. As mentioned, I am finding eating butter before I head to bed has been very helpful in getting a good nights sleep. I’ve heard the same from quite a few people. However, having said that, I know that when I fast for more than 24 hours that it’s very likely that only sleep for a few hours and then I’m fully alert. So, if calorie deprivation results in sleeplessness when fasting, then maybe there’s a more general relationship at work between calorie intake and sleep. Maybe I’m simply not consuming enough calories in general on a day to day basis? That said I’m planning on upping my calorie intake by 25% by increasing my fat consumption and see how that works out for sleep. I’ll add that my weight has been rock steady since I lost the extra body fat. My bmi is higher than yours, but I’m also 43% muscle per the omron impedance scale.

[@gt27312]

I'm an elderly woman who's been keto for 4 years. I follow that protocol to reduce inflammation and weight, but also because of the dementia that runs in my family. I do my best to keep my cognition high so I have recently started to take exogenous ketones because I heard it was valuable for brain function and health. Whether it is a placebo effect or actual improvement, I experience increased clarity and awareness when I take exogenous ketones before a "study" session. I have not experience much difference in weight control but I do feel some improvement with inflammation. Thank you for sharing your knowledge and experience with us in a way that even laymen can understand!

[@missymeaux]

What brand do you use if you don’t mind sharing?

[@gonefishing7813]

I work for our State Court system I’m on call 24 hr…if I’m called out during the night, which is very normal, sometimes when my sleep is interrupted early in the night usually around midnight I wake quite “addled “. I take a ketone “shot” as soon as I get up by the time I arrive at the scene of my call out, I find my head clear fully prepared to deal with the load of detailed paperwork required

[@sheila7814]

Where do you get your ketones? Type?

[@jobrown8146]

This "student" is learning more from these lectures. Thank you very much.

[@englander2626]

Thankyou for the excellent video. There are a lot of recommendations to take coconut oil and MCT oil. But it's unclear to what degree these oils are converted to keytones for people who have elevated insulin levels. If you could do a companion video to this one to clarify MCT oil and keytones that would help a lot.

[@marklifestyle]

Dom just had a talk about this on Westman's Adapt. He say MCT is the poor man's exogenous ketone and processes quickly, however, he added that taking exogenous ketones with MCT oil kept the ketones in the blood longer creating a synergistic effect. He also said that D BHB will not show up on a blood monitor. both D and L BHB are a combination that works best for most people, D being bio identical

[@enzogaibisso9691]

When I first heard Ben spoke, I was so excited. His knowledge is so incredible.I have re-watched pretty much all of his videos. I can’t get enough. The condition of the blood is truly life altering. I’m a carnivore for over 5 years. Thank you for your service. God bless

[@CarnivoreScott]

Thank you Professor Bikman! I really appreciate your dedication to bring knowledge to the masses. I know your content is forever pushing the boundary of my ignorance back, it seems a never ending task. So again thank you for all you, and your team are doing. More informed patients is how the medical establishment will come to know these things you are teaching. I feel for Dr's and medical professionals as they are in a very tightly controlled line of business. It isn't only the customers (patients) they are trying to keep alive and or well, but the hospital administrators, investors, Big Pharma, Insurance, and of course the legal community. With so many pressures and so much at risk I can see how one would be required to stand on the platform of "Standard of Care." It's sad, but like my ignorance none the less true. All this to say thank you for helping us in the battle to secure better health.

[@benbikman]

Thanks, Scott, for your kind comment.

[@ianstuart5660]

No excuses, ever, for causing deliberate harm to others!

[@parmindersingh6986]

I’m on 9 years 0 carb lost 55 pounds but belly fat never gone. Very high protein low fat. Now last 5 month I eat very high fat like 200-300 grams fat 60-90 grams protein I gained muscle and lost belly fat . My glucose under 80 ketone all ways 2.5 to 3.9 . To much energy. Day time only eat ghee with coffee night eggs yolk small steak some bacon add more butter.

[@jaykana7677]

I am having the same problem, just belly and a bit of chest fat,will increase my fats.

[@punchkitten874]

​@@jaykana7677Dairy fats contain a hormone which helps babies put on weight. Dairy can stall or reverse weight loss on the carnivore diet.

[@vonticehembree6083]

@@punchkitten874 does that dairy you’re speaking g if also include heavy cream ? I use heavy cream in my coffee , I stopped drinking milk 2% 2 years ago . I’m curious if that includes heavy full fat cream?

[@punchkitten874]

@@vonticehembree6083 Yes, it does include heavy cream. I recently quit coffee, but I used to drink it with salt and heavy cream. Five pots a day!!! I wouldn't worry about it if you're only having a cup or two, but at my rate, it was my only calories for most of the day, and I called myself OMAD. 🤦 btw, quitting coffee wasn't nearly as bad as I thought. Yes, I had a headache, but bc I hadn't been eating during the day, quitting coffee led me to an easy 24 fast. The fast seemed to give me energy, which was weird, but I got over coffee in just a couple days (I quit bc $$)

[@vonticehembree6083]

@@punchkitten874 I’m only drinking one cup a day , rarely two . But it’s something to think about

[@donaldmcpherson3226]

Damn, you hit it out of the park with this class. You filled in some of the holes I have been curious about. It is a privilege to attend the metabolic classroom.

[@karene9446]

Dr. Bikman, I use them to get back to sleep. Insomnia's been a problem for decades now - especially when I'm in ketosis and for some reason, I can get back to sleep if I drink a gulp (I use HVMN's ketones.) They are also a tremendous help in reversing the grogginess and brain fog from lack of sleep. It seems counterintuitive if I'm already in ketosis, but I wonder if my body needs the energy to rest well. I notice a difference pre-exercise, but the sleep assistance is the most powerful. Oh, I should also add that they're just as effective if I've eaten enough carbs to take me out of ketosis.

[@nataliajimenez1870]

Maybe they reduce stress hormones pathways for you, allowing you to sleep. Many people that fast see an increase in their stress hormones and find it difficult to sleep.

[@karene9446]

@@nataliajimenez1870 Interesting! That makes a lot of sense - I'm particularly sensitive to stress. Thank you!

[@porterhousegirl]

I’ve been using exogenous ketones to help extend my sleep time. I would drink them a few hours before bed and it worked until it didn’t. I went from sleeping 2-3 hours to 5 1/2 hours and reverted back. However, I never thought about drinking them when I wake up in the middle of the night!!! I will try this tonight and see what happens! ❤

[@karene9446]

@@porterhousegirl Good luck! I hope it works

[@megm.c4026]

Thats because of Tryptophan I believe. It needs to get across brain barrier and doesnt very well when in ketosis. Lots on you tube about it. Thomas Delauer has some great vids on it and how to fix...worked for me without buying supplements, which I try not to do although he mentions exogonus ketones also as possible way to fix. Very common issue.

[@Nyt250]

Socrates was known to fast, sometimes for several days, in preparation for debates and discussions and the like. Even this ancient, wise man knew that fasting (being ketogenic) was beneficial for the brain. Insane! Fasting is such an ancient and wise wisdom that we have forgotten. We must bring this consciousness back!!

[@nancyarchibald9095]

Whenever I get deep into ketosis via low-carb eating, I get this brain surge of focusing on the tasks at hand and the tasks on the back burners. I will clean out reorganize, improving our home centers, closets, sewing rooms, and many other cluttered places. I love it!! ❤️ 🏡 😊

[@robinq5511]

Ketone-IQ Pre-Workout: I take the 35 mL dose 30 mins before my 1 hr workout with a trainer. They boost my energy, mood and suppress my appetite for 2 to 4 hours. I usually take them fasted or after my decaf coffee with MCT oil depending on when I am going to the gym. I am a 74 yr female who is recovering from prediabetes & insulin resistance - thanks to you and a low carb diet! They do literally taste like cr@p but I keep mine chilled and down 8 oz of water immediately after. I have not experienced any negative side effects. They cost the same as the bioidentical ones you suggested but you get more servings. I test my ketones after my workout and they range anywhere from .5 to 1.5 probably due to the intensity of my w/o and how long I have waited to test. I also seem to have better recovery when I take them - less stiffness and soreness.

[@lesworks]

When I was in school in the early 90s (dietitian) I was clearly taught brain and nerve cells prefer glucose as fuel. During the era when they started upping CHOs for for diabetes and relying fully on erogenous insulin. Retired by a decade, I literally have had to unlearn so much since then.

[@KamfaKing]

I can't *Like* these discussions enough! Thank you once again Ben.

[@davidcottrell1308]

very cool! basic carnivore here...I am never hungry, have absolutely no cravings....I find your detailed explanations really helpful.Thanks for everything you do!!

[@pascalebarnes1068]

Hi Dr Bikman, I used exogenous ketones when I had covid recently (first time of having the virus). I took 1 bottle of KetoneIQ ketone ester per day, over 3 days, in the morning with decaf coffee and sine Mct oil and noticed a calming effect and less brain fog than when i first awoke. I was already on carnivore diet. My flu-lime symptoms were of shorter duration (2 days) than my husband, who got it (4 days), who wasn't on a very low carb diet and was not using exogenous ketones.

[@lindacontreras8862]

I use keystones from Dr Boz, her pucker up are very tart, I love them. I’m 2 months into a very low carb ketogenic state. Using keystones I measure with a keystone meter/bg meter and my numbers are going up including my fasting bg going down and keystones going up. I am zero carbs but not fasting eating only Sardines for 4-5 days. I do have some of the mast side effects of ketosis. Keto rash and the feeling of high cortisol/adrenaline on waking and calf spasms while trying to sleep during that 3am-5 am window. I take magnesium, including bathing in it. Weight is coming off. BMI is 24. I’m 64. Inflammation is way down, joint pain. Gone, sinuses feel better than ever. Ears, nose and throat a problem my whole life finally getting relief and breathing better. Drink plenty of water with salt. Love your book and channel. Live any feed back from anyone on these cortisol issues I’m having 😊

[@FocusProj]

5:30 just realised that those with insulin resistance, have a metabolism that is forced to use more glucose than ketones.

[@MartyRaaymakers]

Yes, same here

[@truthlover11]

Why wouldn't we use more fat from our cells instead of glucose?

[@truthlover11]

Lord have mercy!!!❤😢 please I need to lower my insulin..with depleting ALL MY ENERGY.

[@FocusProj]

@@truthlover11 When you insulin is elevated, your live can't enter keto-genesis.

[@cassieoz1702]

I find the constant use of the term 'insulin resistance' unhelpful (notwithstanding everyone spouting a different pet theory on the cause/mechanism). Ben has previously said that IR always coexists with hyperinsulinaemia so I find just using that term helps me understand what's happening.

[@melanieprudhomme-leek4807]

Always learn something new. Appreciate your content!

[@robinq5511]

@26:00 American ketones how to take I have used ketone - IQ, which is the Esther form and also the BHB salts and have noticed the calculus buildup on my lower teeth, which is not fun to deal with. I take them on my workout days for the extra energy and motivational mood. It is good to know you can also use them for that nighttime snacking I just hope they don’t keep me awake… Thank you so much for sharing this info. I have been looking for.

[@sherrysherry5972]

I've been using exogenous ketones and recently began to question whether they were the right path. My goal is weight loss, pain, energy and gloomy mood! Your lectures are great! Thank You. You speak to me at a level that is detailed orientated but not too much over my head! I've been following the Keto diet for years but recently became very focused. Began 24 hour fasting. I backed off of BHB because my insulin refuses to go any lower and I needed to do a bit of experimenting to see what I could change. I previously found I did not like Ester type BHB, headache, not energizing. The salts make me feel good, to the point I felt guilty indulging in that burst of energy and clarity. I plan on giving the bio-identical ones a shot. Please keep sharing your knowledge, you are excellent at this!

[@KevinSmith7]

Thank Dr Bikman. I have been Keto/Carnivore for over 5 years generally in some level of ketosis. I have noticed increased "plaque" on my bottom front teeth and couldn't figure out why. No where else, and i maintain good dental hygiene. Your insight makes sense! Hoping i am not building up kidney stones....

[@Carnivoreteacher1965]

Thank you, Professor Bikman! My question is this: Will exogenous ketones cause my own body to not make my own endogenous ketones in a similar way as when a person injects exogenous testosterone, their body tends to not make its own because it’s getting what it needs from outside?

[@amyferguson6573]

Thank you for all your lectures you’ve added so much to my knowledge and understanding of how to reverse metabolic disease. I was a T2D which reversed 4 months on keto/carnivore but still have insulin resistance after 20 months, which I’m hoping to help reverse using exogenous ketones. I also am medicine resistant Bi-polar II (T2D was caused by the medications) and a recent study was showing how ketones could improve and balance out brain chemistry. A keto/carnivore diet has improved my symptoms but am going to try exogenous ketones and see if there’s any improvement. Thank you for all the details on how ketones work and that exogenous are safe. Also thank you for mentioning a preferred brand it saves time and money.

[@amyferguson6573]

Question: Do exogenous ketones have to be in liquid form or can you get them in a capsule?

[@JimWooddell]

I use an exogenous ketone product that uses raspberry ketones as it's primary ingredient. Raises my blood ketones by 1 to 2 points within 2 hours. It is difficult for me to maintain a theraputic state of ketoses and these really help on those days my GKI will not go down.

[@tearose3763]

Ive used them when i know my cravings will go up, i am physically disabled and overweight but am on the mend metabolically! Thank you from the bottom of my heart for your studies and shares?..as a medical professional this is such valuable information for others to understand. 🙏🏽🙏🏽🙏🏽

[@ihrwimpernspezialist4941]

Could you give the link to buy thees recommended keatons, please?

[@Dhyan333]

Incredibly helpful. So clear. You are a great instructor. I plan to understand this material completely and pass it on when people ask " what are you doing?" I'm obviously doing something different ( low carb life). I wish you had included use of MCT OIL. Please do a lecture that includes how and when to use MCT oil.

[@nancyarchibald9095]

I don't think he's a fan of MCT oils, if I recall. He'd rather see us use our diet wisely. Funny, how I remember his comments about that from back in 2019.

[@kajatrees]

Thank you so much, that clarified a lot! I know I will be rewatching the video, it's so helpful and a somewhat less-covered topic! I have not used exogenous ketones so far, I have only got into ketosis through eating low-carb or almost no-carb, as well as fasting. It takes 2-3 days for me to get into ketosis after eating carbs (I haven't cut them out completely, for example I do parttake for birthdays etc). I am still testing this out, wearing both CGM and continuous ketone monitor to try and understand what affects me how, so I am very curious about this topic! I seem to have some insulin resistance, but otherwise my health metrics seem good, with blood pressure even being on the lower side. Even when I have reached ketosis, I sometimes get out of it again despite eating only meat and eggs for example, no strenuous exercise etc (example from yesterday), which makes me wonder... You mention in this video that insulin is the driver of the level of ketones created. Can insulin be created without carbs being eaten? As there is no continuous insulin monitor, I have to deduct insulin level from carb and ketone levels. I know blood glucose level goes up when I go to sauna (and I love sauna) - does this raise insulin right away as well? Curiously, when I was at a spa and spent time alternatingly in sauna and in cool water (20 degrees Celsius, so not "cold" like most cold plunge research), my ketone levels jumped up when I was in the cool, instantly down again when I was in sauna. Does this mean that cold plunges make ketone levels go up? In your video you talk about breaking down nutrients (both carbs and fats), but I didn't hear you mention if it is the same citrate cycle when using our body's own fat? I am sorry if it should be obvious, it's just that I am trying to learn from all these different sources and this link is so far missing in my understanding. So many topics that are interesting here and I hope you will be covering these and more in the future! Always extremely grateful that you are educating us like this. I am in IT myself, so completely different field, but I am obsessed with understanding how to make myself healthier! Your channel here as well as so many interviews in different places, and InsulinIQ free course (didn't take the paid one) and your book and the Instagram reels... Amazing and huge thank you!

[@donnahelps5680]

I’m wondering if continuous use of exogenous ketones would down-regulate the liver’s production? I know the body is both clever and miserly, so would the spilling of calories via ketones in breath and urine continue indefinitely?

[@lindapestridge3073]

Always Learn something new watching your videos Dr Ben .

[@MrRobinGoodhand]

Hi Ben, when I heard you mention Dr. Stephen Cunnane, I wondered if you were going to mention MCT oil. Apparently our bodies have the capacity to convert MCT oil to ketones. I am also reminded of Dr. Mary Newport's experience with her husband's dementia, and how the MCT oil made some improvements for him. I do not know if you could consider this a source of exogenous ketones or not, as the MCT oil has to be converted to ketones once digested. I make a super delicious salad dressing which I encourage you and your listeners to try. 1 tsp dijon mustard, 1 tbsp apple cider vinegar, and 3 tbsp MCT oil plus a dash of salt. It's a tasty way to get the MCT oil in me as I do not like bulletproof coffee. By the way, it is a completely taste-free oil, so good for consuming with other foods.

[@lynlawley8903]

I had heard this too

[@p.krishnaveni7813]

For everyone reading this, finding the banned book called the hidden herbs by anette ray should be your top priority

[@marklifestyle]

Can insulin created with a protein drink be enough to trigger fat storage

[@theskyehiker]

I don’t know how you can say this book is banned. I did a quick google search and found it in five seconds. It is available as a pdf.

[@normameyers4904]

@@theskyehikerthey say that to get more attention.

[@VilladeltaConstruction]

That was so clear! Thank you! I’ve subscribed and will stay tuned ❤.

[@vonticehembree6083]

I have tried ketone IQ, I didn’t see any great result but I’m not giving up on it . I tried another one that tasted like an orange dream sickle and I felt a definite amount of energy . Name : REAL ketone . I usually stay at. 6mmol thru keto mojo monitoring . Not sure if this low level of ketone is really beneficial but at last my A1c stays at 5.3 which is more important to me . Thank you DR Ben . I love learning from your classes

[@vonticehembree6083]

.6 mmol not 6 mmol

[@roberttesar2484]

Ketone IQ is not a true ketone ester. It is only the diol which is an alcohol and will give you a buzz if you drink enough of it. DeltaG or KetoneAid are true ketone esters.

[@nannygranny9534]

The best thing ti happen for my health is finding your videos and now your classroom!!! I have been following your advice and my blood glucose is down. Making keytones comes and goes but at least I am finally making some that are measurable. To keep them I have to have less than 20g of carbs a day.

[@genegroover3721]

Be thrilled! I continue to learn something new from you almost everytime i listen to your lectures. I keep coming back for more.

[@Ronlawhouston]

I think you gave an excellent presentation of Ketone metabolism. Do you think given the cost that exogenous ketones are worth it? I have a difficult time seeing the real benefits of higher ketone levels. It seems nutritional ketosis is sufficient.

[@Chippoka]

I don't use exogenous due to thier high cost relative to just using Bulletproof C8 MCT oil which converts to ketones fairly quickly; so I'll sip a little at work if my mental clarity starts to fade; or, sip while on the long commute home if I start getting too tired whist on cruise control. In both instances, the results are fast and effective. I also use it after a rare sweet treat to help bump up my metabolism (based on some of the work Dr Gundry has reported in his books and video about "mitochondria decoupling"). I find I can get back to burning fat (gained during a lax few days of eating carbs) sooner by doing that.

[@cmorrison5466]

@insuliniq I purchased the ketones from American Ketone and I mixed the 2oz with water in the empty bottle provided. The only thing I don't see is how much of the mix am I supposed to drink, when or how often? I love the sour taste, too. I have been Carnivore for over 2 years (Keto for 1 year before that) and am normal weight. I used to smell ketones every time I exercised. I no longer smell them and unsure why. I exercise daily and I wanted the ketones to curb my nighttime cravings and help with exercise recovery. I would appreciate any advice on how often and how much to take. I am a 63yo female, 120lbs. Thank you very much!

[@dorsetboronia6744]

Thank you for this info.Brilliant. But what about MCT oil.? I am 81 yr female in Australia. Just diagnosed with mild to moderate white matter disease. Am carnivore. Hoping exogenous ketones will slow progress. Is there any hope of that? Many thanks.

[@forajc]

Ben you mention that you use "Original Ketone" by American Ketone. Is this still available? Their website seems to indicate that they do not exist anymore. Any other ketone supplier recommendations?

[@SHalto142]

Thank you for this. I have been worried about exogenous ketones even while I'm struggling to get into ketosis through diet. And for the discussion of salts, esters, and bio identical BHB.

[@nataliajimenez1870]

Maybe using exogenous ketones can act as a bridge to help ramp up the metabolic pathways for ketone metabolism. There's definitely an adaptation period going from a high insulin state to a low insulin one

[@zerocarbdoc]

Always appreciated!

[@FocusProj]

Thank you for sharing your immense expertise and knowledge with the world. Another outstanding contribution from distinguished Dr. Bikman to the discourse on health and metabolism! :D

[@flash3047]

It would be useful if a you could have discussed how long ex ketones last in the body? Especially the new type you take from American ketones.

[@NorthStewart]

My blood ketone levels never get above a 0.2 even after a three day fast. Is this common, and will exogenous key tones help my body to get into ketosis better?

[@hektor6766]

Try resistance exercise first, if you don't already. And break the fast with fat, not carbs.

[@triwithms]

What an amazing talk, glad I stumbled across it. You mentioned the benefits for brain health and possible uses for people with epilepsy. I have a few conditions in the brain, multiple sclerosis, brain cancer (non-operable), epilepsy (was having 1-10 seizures every day for the past 6 years or so). Have tried multiple different meds without much success (currently taking 2). If the primary outcome desired was reduced seizures, do you think it is possible and would there be any potentially dangerous effects on the other conditions in your opinion? I also have auto immune type of anemia where my body destroys red blood cells resulting in very low hemoglobin and low energy as well as cognitive impairment.

[@EvgeniiaDolinenko]

Dear Dr Bikman, ❤ you are amazing ❤ I hope you can do a video about gluten as a cause of hypothyroidism . You mentioned that in one interview . I also hope you can talk about food sensitivities, histamine and insulin, if there is a connection.

[@robertobattiston1]

I learned something new! Thanks Doc!

[@fredsmit3481]

Dr. Bikman, thanks for this video, I learned a lot. I've been in ketosis for many years and like many people posted, I would like to sleep longer - I sleep for only 5 hours and I'm tired during the day. I'm experimenting with sodium-bhb salts and increasing my potassium. I recently took potassium chloride and sodium-bhb in the morning and had more energy during the day. My next plan is to reduce it to just one variable at a time and then try taking the bhb salts at night. If they both help, then I may switch from sodium-bhb to potassium-bhb.

[@ttiller3744]

Try eating some fat before bed time ( butter , ghee)

[@6140LIBRA]

Does the body slowdown making ketones if you keep taking exogenous ketones?

[@marisa9600]

Dr. Bikman, what do you consider "low insulin" to start the ketone cycle? For a prediabetic, whose fasting Insulin is high, can they get into ketosis though fasting or low carb diets, or will it take dropping fasting insulin to normal levels ( which I understand can take years)? I am confused by this point.

[@jobrown8146]

I went low carb in Oct 2021 after being diagnosed with diabetes. I could tell by my breath that I was in ketosis within the first 3-6 months (I never measured them and it may have happened sooner). My diabetes had been remitted by the 3 month mark. Dr Ken Berry recommends Vitamin P = patience. Remember that it has taken time to become prediabetic/diabetic. It's going to take time to reverse it, but I personally think that it happens faster than what we expect it to if we can stay away from the carbs and processed foods. I have found Dr Eric Westman and Dr Ken Berry videos helpful. I think some people get a bit too caught up trying to measure things. Some people need to do this to keep them motivated. I could tell by my body shape/size and how I felt that low carb was working. I don't measure anything because I like to keep it simple; occasionally get on the scales. Wishing you all the best. BTW my fasting insulin was measured for the first time Dec 2022 (so no benchmark unfortunately) and it was 7. By mid 2023 it was 5. My low carb doc likes it to be between 2 and 5. Wishing you all the best.

[@sheilawebster538]

Im a Lean Mass Hyper Responder. I dont take exogenous ketones but i do have a huge problem with calcium/ plaque deposits on the front of my lower teeth. No amount of brushing or flossing gets rid of it. Am i naturally producing it from my erogenous ketones? How do i get rid of it?

[@willowraine5514]

Could be you are excreting Oxalates.

[@paulastiefel5654]

I have the same issue with the lower teeth deposits, and am wondering if it’s from endogenous ketones or oxalate excretion. Perhaps we need more calcium?

[@Lovescoffeeandtea]

What about MCT oil?

[@drambuie4081]

I’ve heard that too much MCT oil can lead to fatty liver. Any truth?

[@seanvogel8067]

Thanks!

[@benbikman]

Sean, you’re too kind. Thank you. Certainly not expected but much appreciated. Please let me or my team know, on our website at www.insuliniq.com if there’s anything we can do to help you. Thanks again.

[@nanray8415]

Alrighty then! Using Keto for weight loss myself. Also TBI, facial fractures and brain bleed 4 years ago leaving me pretty addled. So much benefit! Also, dealing with the brutal murder of my sister, the aftermath, the trauma to her children, grandchildren, our siblings, our elderly parents. Just learning and trying Exogenous ketones. Today was a good day to put it to work. Had a family gathering yesterday, it was sweet, Sis is missed so much especially as we were a great team to cook for our crew as well as in our days of farming, ranching and mining. Best scratch cooks in the region, and she was a star. All the food was lovingly made. I came prepared with ketosis on board plus all I needed to resist yet cook. I had no hunger or cravings. I was emotionally attracted and my soul was nourished by sharing the meal, so I did. Home later, I caved and binged while grieving. 225 carbs to my best count. This morning felt it. Guts were brutal. Out of Ketosis. So took a dose of BHB in water. I used Real Ketones, Elevate. Had bought it a couple weeks ago in a sale at our Walgreens. 1 hour later showing ketones on the urine stick. Calming in my mind, gut pain eased, reflux eased. Using Dr. Boz suggestion to NOT fast, I fixed us and ate breakfast. I feel good that this works. I used the BHB last week to manage sleep, anxiety and nightmare problems. I saw a difference, but was still nervous about using them. This experiment this morning eases my concerns alot. Thanks Doctor!

[@allsuperlady]

1 year TBI bleed survivor here, just started drinking ketones to see if it helps.

[@nancythomas2193]

Dr Bikman, this is the first video of yours I have listened to. I was researching exogenous ketones. I have a grandson who is non-verbal autistic. A friend had sent me some information regarding ketosis and autism stating that exogenous ketones may help such individuals. The focus was on non-verbal children. When they were in ketosis they spoke; when they were not in ketosis they no longer spoke. I'm wondering if you or anyone else may be able to address a relationship with ketosis and autism.

[@RickinICT]

I've read that there is strong evidence of glucose hypometabolism in some parts of the brain in autistic individuals. Perhaps the ketones are offering those hypometabolic neurons an alternative fuel that they are better able to utilize? Try searching for "hypometabolism in autism".

[@derekjsmith7662]

Great content great presentation speed

[@InconnuGlitterBoy]

Excellent lecture. Thank you.

[@benbikman]

Thank you, @InconnuGlitterBoy for your kind gift. Certainly not expected, but much appreciated. Thanks.

[@CoyoteWindRanch]

Question. If I’m always in a state of ketosis will taking exogenous ketones even be helpful? Awesome lesson as always!

[@AngieFromDownUnder]

G’day Dr Bikman I have a question… What do you think of MCT oil (C8, C10)? I take a Tbs in my 1x coffee most days (with 1 Tbs each butter and cream). I eat predominantly high fat, mod protein carnivore. Or would you say the exogenous ketones are better? Love your videos, thank you 🙏 Angie from Down Under

[@katiequ2058]

My 94 yr old mother started exogenous ketones five days ago. I’ve been preparing all her meals for sometime and cleaned up her diet, however, despite this she was still having cognitive decline and extreme agitation that was getting worse. After just 5 days and only half the recommended dose her agitation is nearly gone and more like herself. Big question I have is how long can she stay on exogenous ketones ?

[@KarenScott6]

I have considered taking them. I have not eaten for 40 hours and just taken my blood sugar and it is still 5.4. I have had a cup of tea with milk so I think that is what stops it going down. It rarely goes lower than that and doesn't go really high either. I am carnivore and have stuck at the same weight for 8 months. I could really do with losing another 60lbs at least. Milk is my nemesis and I need to bite the bullet and cut it out. But I have considered taking the ketones to see whether that would help

[@Julia29853]

Maybe try a little heavy cream instead of milk. Pure only ( no gums added). Kalona has a delicious pure cream. There are a few other brands. It has 0 carbs

[@sheila7814]

Lots of walking

[@q.d.mcgraw]

Would a type 2 eating strict carnivore that can't get their glucose/insulin levels down benefit from exogenous ketones or could it push them to ketoacidosis?

[@turtledunkknucklebaby8089]

I wonder if American ketone original is the same kind of formulation as Keto IQ?

[@rosenelissen2692]

I always learn something from you Mr. Bikman. Thank you.

[@starius1154]

Dr Bikman, thank you for this info. I keep hoping someone will talk about using exogenous ketones in the setting of epilepsy. We've known about the ketogenic diet being an effective treatment for lots of seizure disorders, and I've often wondered how exogenous ketones would affect someone suffering from epilepsy. I'm in the EEG field but still have not heard anything about anyone trying this. If you ever run out of research ideas, feel free to have this one! Thanks again. (PS I've tried the salts and the esters. I'll have to give your suggested brand a try next!)

[@fronniebealer7808]

Your info has helped me not to be leary of the wastefulness in the usage of exogenous ketones.

[@teknatruth]

Another great video! Thanks for taking the time to make these videos. I really feel like I am back at college learning about these things. In one of your videos, your analogy about the manual stick shift driven car really stuck with me and brought home the message of what happens in muscles when you burn ketones and when you burn glucose. Glucose, the engine is revving but not in gear yet, can't do much work. Ketones, the engine is revving and can now do work. You are the insulin expert in my mind. Keep up the work!

[@victoriakleeberg2806]

Can you talk to mct oil . C8 - is this a form of exogenous ketones ? I feel I do a better gym session or a better tennis morning

[@christinehanks1053]

Yes, I am wondering how long it takes to raise blood ketone concentration with actual exogenous ketones versus c8 MCT oil, taking into account the dose consumed and the levels achieved. I wonder if there is any literature on this.

[@victoriakleeberg2806]

I find adding mct oil to my morning weak long black coffees with lots cream results in positive urinary ketones +1 ie beyond a trace for sure.

[@mattfisano]

I have been using them in coffee before workout. 12oz of coffee, 25 grams of protein powder, big serving of ketones and one scoop of MCT oil

[@lou-annatkinson4211]

Hi Dr Bikman, I have NAFLD, I am 70, I am not a drinker, I am in ketosis, av daily glucose 5 - 6 mmol/L and Ketones 0.8 mmol/L. Q- can the fat in my liver be burned up / used up. Not sure of correct terminology. Would I benefit from exogenous ketone supplement? With no programmed exercise, just daily life, I have lost 6kg in 5 weeks. Thank you for the help you give us to manage our own health ❤

[@davidnannalockwood3133]

I'm interested in trying them for migraines.

[@ActivateMission2ThisTimeline]

They gave me a headache. Not sure about the bio identifical one he mentioned. Good info on that type. May try it

[@barkeater7867]

So whats the recommendation on exo ketones?

[@loisbrown503]

HERE'S HOW I USE THEM: If I've eaten significantly more than 50 gm. carbs one day, the next day it can be hard to get back onto very low carbs. Even with a fat+protein breakfast, by mid- morning I might feel weak, so that's when I'll chug the little bottle of exogenous ketones. For whatever reason, I do feel better soon after. Thanks so much for this course!

[@LibertyLuvr]

What level of ketones were you targeting when you tested and confirmed the increased metabolic rate of adipose tissue?

[@Maggied50]

I have started using ketohol (R1, 3 butanediol) in the evening to replace my wine habit. It has a slight calming affect without ethanol and ketone benefits.

[@caspianlake8475]

Can you address the rec to rotate in and out of ketosis please?

[@phardim]

In Kreb's Cycle, at the point where the insulin level directs the conversion of excess Acetyl CoA to become either ketones or fat; what is the corresponding glucose level? I can measure blood glucose much more easily than insulin.

[@agnesmercurio7693]

Would taking BHB ketones hinder burning of one's own body fat to make ketones?

[@ScienceAppliedForGood]

Yes, research shows just that. So if you want to lose weight then endogenous ketones is the way to go. "Exogenous ketones from either intravenous infusions (Balasse and Ooms, 1968; Mikkelsen et al., 2015) or ketone drinks, as studied here, inhibit adipose tissue lipolysis by the same mechanism, making the co-existence of low FFA and high βHB unique to exogenous ketosis." The citation was taken form the paper below Stubbs BJ, Cox PJ, Evans RD, Santer P, Miller JJ, Faull OK, Magor-Elliott S, Hiyama S, Stirling M, Clarke K. On the Metabolism of Exogenous Ketones in Humans. Front Physiol. 2017 Oct 30;8:848. doi: 10.3389/fphys.2017.00848. PMID: 29163194; PMCID: PMC5670148.

[@krabbend8]

Thanks again, dokter! just a question: while using these exogenous ketones, is there anything that controls your insuline down at the same time?

[@williambuckley6128]

How do ketones affect cancer cells in the absence of glucose and fasting insulin of 2?

[@Mark4Jesus]

Some types of cancer feed on glucose, some on fat, and some on both/either. So it probably depends.

[@annabanana7752]

Ben, Since breast cancer is so prevalent. Will you please talk about insulin resistance, elevated blood sugar, metabolic syndrome and why it is so important to change diet now and after surgery so it will possibly reduce the risk of recurrence. RN here, people do NOT understand that progesterone and estrogen are released from fat cells. So reduction of all over body fat will help. I hope one of your moderators read this. There are too many MDs that do not emphasize the importance of maintaining low insulin and eating low carbs is a positive change overall. Thank you.

[@sheila7814]

Yes and I was diagnosed last July, gone through a year of change, including good things. I changed my diet, exercise every day. Walk many miles and have lost about 25 lbs since last July. Go away fat! Go away stored estrogen! I don’t want it to come back. I study science as well…. And I tell everyone at the cancer center I go to, to do this. Have helped some get started with their change as well. I feel fantastic even though I had a dbl mastectomy. Wish I had done it all before the big C!❤

[@JennySullivan-l7t]

Thank you for a clear and complete explanation of ketones!! I use exogenous ketones for energy and in the evenings to satisfy cravings as well but not too late as I think they can keep me from going to sleep easily.

[@rosariocuadradoalarcon9772]

Hi from Soain Dr Bigman , thanks so much for sharing your knowledge . Talking about cravings , what is your opinión Is it possible we feel hungry because we dont eat enough ? What is your opinión about OMAD ?

[@ausmiku]

No mention of beta-oxidation of fatty acids ? Isn't it an important part of energy production from triglyceride fat metabolism ?

[@angelagould54]

Dr. Bikman, your colleague Dr. Brett Scher recommended exogenous ketone because I have cerebral palsy. I am 64 years old and aqua jog 5 days a week. I have learned that the ketones assist in my muscle spasms.

[@benbikman]

Dr. Scher is an amazing resource and even a better person.

[@robertcooley468]

Are use exogenous keytones when I’m studying or trying to learn something new. I feel like it helps me learn deeper faster and maintain mental focus

[@paulettewheeler4194]

Where can we find the ketones that you take?

[@lylemiller3462]

In regards to ketones and ketosis can you speak to the individuals who are not trying to lose body fat and let's even say have a minimal amount or are below a normal body fat percentage and the idea of ketones and ketosis for that person. I always looked as ketones as burning fat but if you do not have fat to burn how does that work?

[@debjordan4399]

Thank you. Learning from you is pure pleasure. This is extremely valuable information for those of your audience who eat a ketogenic diet.

[@mikeward9870]

I use MCT oil in making my vinegrettes: 1/3 olive oil, 1/3 MCT oil, 1/3 vinegar. Not quite an exogenous ketone, but I prefer foods to supplements. I switched over to consume much more goat and sheep cheeses. (A superb cheesecake: 4 eggs, 1/2 cup cream, 16 oz chevre, 1/4 cup honey, 2 Tblsp almond flour: 40m @ 425 - 12 g honey/piece only slightly bad? ;^)

[@stric10]

Haven't watched yet. I just started supplementing ketone salts in the morning, based on D'Augostino's work. Had / have trouble consuming enough quality fats, they are simply not available where I am at. Autism spectrum + migraines + general lack of energy. I feel amazing with exogenous ketones. That clarity that hits when you first enter ketosis? Yeah, it's that in a bottle.