Extracting the World's Most Popular Psychoactive: Caffeine

Cocaine and methamphetamine are well-known psychoactive drugs, but today, we will be extracting the world's most popular psychoactive drug, caffeine, from tea leaves, and we will see how pure we can get it.
Like many other people, caffeine is my favorite drug. People enjoy caffeine mainly because of its stimulant properties and how it inhibits the chemical responsible for sleepiness called adenosine.
You can make caffeine in the lab, but this is overly complicated when plants biosynthesize it; the most commonly known caffeine producer is the coffee plant, producing caffeine as a natural defense from bugs and other plants; this socially accepted psychoactive compound is found in many different plants as well such as in tea leaves. Some plants use caffeine to drug bees to make them want to come back and get their pollen; by giving a reward of drugs, the plants Pavlov bees into helping them breed, talk about a wingman.
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Chapters:
00:00 Introduction
00:55 Extraction
05:15 Purification
09:36 Analysis
16:46 Retention Drops Off
Thanks for watching!

[@florianstuder3128]

thank you for the subwaysurfer integration really helped me getting through the boring number part

[@megumin1582]

is NOONE gonna talk Bout how he flexes lab grade meth and coke at the beginning

[@BackYardScience2000]

That last skit at the end had me rolling for some reason. Again with the sudden flash of memories. 😂😂😂😂😂

[@WheelerScientific]

Can you tell I’ve never made lines before? Lol

[@williamneubecker]

@@WheelerScientificlol yeah that’s pretty clear (Probably a good thing). My eyes started to water watching you try and wrangle those huge lines on salt😂

[@danielgreen6302]

@@WheelerScientific Hey Silly Question is it really true that why tea caffeine doesn't really effect you due to a certain molecule. If so or not; Please explain or if you are indisposed I understand, Thank You for reading regardless.

[@BackYardScience2000]

You saying the boiled tea leafs smell like fresh cedar wood really brings back memories for me. Me being a logger by day, it *really* brings back memories. I love/hate that smell for many reasons.

[@theneonlobster]

This is one of my new favorite channels. Great content!

[@WheelerScientific]

Thanks, glad you enjoy it!

[@strade601]

To get rid of the annoying filtration step (and possibly increase the yield), you should try a Soxhlet extraction if you got the glassware. Using boiling benzene as a recrystallization solvent also greatly helps getting rid of leftover tannic acid.

[@philouzlouis2042]

Hi Wheeler Scientific, Nice video. About your caffeine extraction, you could use a better technique than wet extraction "à la tea making" via a Soxhlet apparatus. That way boiling clean solvent into a closed loop recirculates, condenses and falls on top of your leaves; thus extracting a good quantity of leaves with a finite quantity of solvent. This can be done with CH2Cl2 or with H2O. Regards, PHZ (PHILOU Zrealone from the Science Madness forum)

[@Godwh1sperer]

Dear green chemist: you can simply put coffee into boiling water, filter, boil it down and then stick it in the fridge to get a whitish precipitate of mostly caffeine. You dont need dichloromethane, just coffee, water, a source of heat, a filter and a source of cold. At room temperature, 1gr caffeine dissolves in 50ml water. At the boiling point, 1 gr dissolves in just 1.5ml water. You can directly crystallize from water then recrystallize for purity, no chemicals needed.

[@tracybowling1156]

I HATE caffeine. I do not like the way it makes me feel. I wonder how many people feel the way I do? Anyway, your video is very interesting as usual! 😊

[@watterztrail7870]

How does it make you feel

[@Agent_oldly]

Bro had to pull out the subway surfers

[@noelswedzinski4498]

The Subway surfer tactic had me rolling,😂😂, I wonder when code channels will implement this method.

[@nikoivan2580]

How many mg of caffeine you want? Yes.

[@anthonyrickardii6198]

That’s pretty awesome! You should try with Solanaceae

[@infectedrainbow]

What you did with the game while analyzing the data. That was...incredibly helpful. Is there a name for this?

[@user-uf8gu9ne1g]

Caffeine should be great NHC precursor

[@MrYellowOffical]

What are thesse weird stoppers or Joints called in ur Destillation?^ And btw is this ur Home Lab?

[@RitikKumar-zh8fm]

Hello sir how make iron+antimony star regulus pl. Rep.

[@Correct_Opinion]

Very cool

[@user-ov4xp2fn4j]

Please do making polonium-210

[@salimshady6100]

Recrystallization for the winnn😤😂

[@allenbates3470]

so does crystallization occur in an 100% pure form?

[@WheelerScientific]

Chemists rarely say its 100% pure, so it recrystallization is just used to increase purity, and not all cases of recrystallization even come close to pure. As some chemicals undergo co-crystallization. Let me know if you have any other question or clarification.

[@GorVala]

What about that Cracain 😂😂

[@deamoneater357]

You can make a pseudo crack with caffeine.

[@GorVala]

Sugar is a drug 😂😂

[@mistercornell4755]

your my favorite druggie

[@EgonSorensen]

After going keto-diet, I found out that dark chocolate contains about 1/3 its weight as natural caffeine - and I didn't sleep much that night. Apparently it has other psychoactive properties too :ø)

[@Spubaru4U]

WTF is up with the train game?

[@markedis5902]

Sintering not sinIStering

[@squizitzithatsitalianforyu4782]

Squizitzi that’s Italian for yummy 😊

[@GorVala]

Get caffeine pills, problem solved 😂

[@bkgaming9174]

That’s not really the point

[@watterztrail7870]

Caffeine pills still have a bunch of other kinds of compounds inside of it so it’s not all 100% caffeine If we wanted to get that caffeine out, we’d have to go through a similar extraction, which would result in a higher yield of caffeine

[@h7opolo]

11:03 "samples that were RUN", not "were ran". omg.

[@neb_setabed]

Thumbs down for the add subway surfers bullsh*t . If you continue to do that, I'll unsubscribe

[@WheelerScientific]

It was a joke. r/whoosh

[@garrettmillsap]

Fkn crybaby

[@charwest5892]

Why are you mentioning cocaine and methamphetamine at all?

[@rosez2980]

Because they are both stimulants like caffeine. But obviously much more extreme.

[@tommustacheless4679]

Most popular substances along caffeine and nicotine

[@tommustacheless4679]

Most popular substances along caffeine and nicotine

[@mistercornell4755]

the real question is why aren't you

[@user-eq8ge2kp6m]

We all know meth and coke are stims but some people do not know caffeine is a stim

[@fryz]

The lines lmfao dare you to do one for science ofc 🫡