Folate deficiency - Megaloblastic Anemia - Macrocytic - Hematology Series

[@MedicosisPerfectionalis]

💉 📜 50 hematology cases: www.medicosisperfectionalis.com/ 😅 If you like mnemonics, try Picmonic: www.picmonic.com/referrals/JK55NQXQQB9JLC119 📕📗 Books that I recommend, www.amazon.com/shop/medicosisperfectionalis/

[@Zain_altouka]

I wish I can 😢 Im from Syria .. I don't have any bank account ..🚶

[@nevinkuser9892]

I'm very impressed with your videos. Such a nice, clear explanation of a somewhat complex topic. Clarity, I find, is the most difficult thing to find in videos these days. Some people should absolutely not be making videos. But you sir are gold, very clear and precise. Thanks again, I'm not even a biology or medical student but I understand what you're saying very clearly. 💪

[@MedicosisPerfectionalis]

Awesome 👏 Thanks 🙏

[@elaineluther1799]

Homocysteine in the blood creates a hypercoagulable state. Therefore, all the complications of homocysteinemia have to do with the damage that can be caused by excess clotting: ie thromboembolic nasties such as CVA, DVT, MI, etc. In the blood homocysteine also causes megaloblastic anemia. Now, medicosis perfectionalis, I'm not sure if you wanted the non-blood complications, but I'll go ahead and give those. Excess homocysteine can deposit in the eyes (causing myopia and ectopia lentis) the bones (causing brittleness and deformities) and the brain (causing intellectual impairment). But if your homocysteinemia is temporary due to a folate deficiency, it should not get so bad that your eyes, brain, and bones are affected. That happens in babies with the genetic defect.

[@MovieBox_Pro]

Folate deficiency leads to homocysteinaemia. Homocysteinaemia causes hypercoagulable states and thrimboembolitic nastis, Right? Then the same folate deficiency causes pancytopenia due to ineffective Haemopoiesis. This means we have thrombocytopenia due to pancytopenia, leading to increased bleeding due to defective clot formation. Now tell me, does folate deficiency cause hypercoagulable or hypocoagulable states?

[@МаргаритаР-д7щ]

⁠​⁠@@MovieBox_Prothrombocytopenia doesn’t stop blood from clotting in hypercoagulable state. In hypercoagulation you just need a little push from platelets to start clotting, you don’t need a lot of them. The same thing happens in lupus with APS: there is thrombocytopenia and still hypercoagulable state.

[@lisasloane3807]

Thank you for not slide reading! Thank you for TEACHING!

[@MedicosisPerfectionalis]

You are so welcome

[@guin8630]

You are great! I have an exam today in two hours, and had 5 lectures of anemia that I couldn't understand because our doctor is so bad at teaching.. yesterday I only studied from your videos and I really feel confident to take the test. Thank you so so much 💕💕

[@MedicosisPerfectionalis]

Very nice...that’s amazing....and how was your exam?

[@guin8630]

@@MedicosisPerfectionalis It was good! I think I'm getting an A+ on this one hopefully ^^

[@MedicosisPerfectionalis]

Excellent! Good luck! Please consider sharing these videos with others, it really helps me! And I am truly grateful! Thanks a ton!

[@guin8630]

@@MedicosisPerfectionalis Sure thing! 🌼

[@MedicosisPerfectionalis]

Appreciate it!

[@reachtt]

I think the beauty of your video is you try to help us remember things, which unlike many professors I know who are just trying to show you how smart they are, listing out facts after facts in their lectures.

[@MedicosisPerfectionalis]

Thank you...I had the same feeling with my professors, unfortunately. That’s why I would like to change that. I want every medical student not to suffer. I will tell the silliest jokes, and make fun of myself so that a student can remember forever...Have fun!

[@youwhatmadeidk]

Medicosis Perfectionalis that’s brilliant :)

[@MedicosisPerfectionalis]

Thanks, dear!

[@vityazsix]

i noticed he sounded a word out slowly so you could see the parts of it and understand instead of just memorizing the word

[@MedicosisPerfectionalis]

Yup! Indeed

[@11ayesharinad27]

Complications are osteoporosis and fat deposit in blood vessels🙏😊thnk u and I really appreciate ur way of teaching. I am going to have my exams next month ur videos really help me out, always.

[@oktamrd]

I'm just so late I have just found your channel. Youre a blessing, thank you for everything you put here for free. 😰😱🖤

[@MedicosisPerfectionalis]

Thank you 🙏

[@orangepeel1366]

ME TOO JUST FOUND THIS CHANNEL AND I LIKE IT A LOT

[@user-qr4te5pv7e]

Homocysteinemia: thrombosis, eye down and out, intellectual disability, megaloblastic anemia

[@kyle610]

i was told mine is low. light headed, blurred vision, depression, fatigue i been getting

[@kyle610]

can food allergies cause deficiency

[@dylanbuckeye]

At 1:29 when you say "pay attention please", how did you know I was playing on my phone?

[@MedicosisPerfectionalis]

My seventh sense can pierce through your soul 🤫

[@queenhelena1515]

LMFAO SERIOUSLY

[@MedicosisPerfectionalis]

😁😁😂😂

[@Sarah-fy2vf]

@@MedicosisPerfectionalis Why 7th what about 6 😊😂

[@MedicosisPerfectionalis]

That’s already taken ☺️

[@whatadrag27]

I'm pharmacy student! You help me alot sir.

[@AnaBellaOfficial]

Hyperhomocisteinemia: Thrombosis, pregnancy complications (abortion, pre-term, neural tube defects), osteopenia

[@nomnomnom3110]

Thank you so much! I wish all my professors were this clear and concise 😊😊😊

[@MedicosisPerfectionalis]

Wow...that’s a boat load of a complement...Thank you :)

[@MsMadamadamada]

Please be the hero we don't deserve and do a cardio playlist (with EKGs would be perfect).

[@MedicosisPerfectionalis]

Excellent! I hope so!

[@loayibrahim1855]

you are perfect .... I'm very amused when I watch your videos

[@MedicosisPerfectionalis]

Thank you so much 😊

[@ilsakhan9631]

3:20 the enzyme isn't homocysteine synthase, rather it's "homocysteine methyltransferase" or "methionine synthase"

[@MedicosisPerfectionalis]

Yes...All the mistakes in my videos are corrected on my website.

[@MedicosisPerfectionalis]

My website is: www.medicosisperfectionalis.com/

[@namatullahsharifi5131]

At 3:15, that's not homocysteine synthetase. It's methionine synthetase. I highly appreciate your time and effort and contribution. Keep it up

[@MedicosisPerfectionalis]

Yes! You’re right. It’s methionine synthase (or homocysteine methyltransferase).

[@gourangomandal6743]

Excellent teaching love from India 🇮🇳

[@MedicosisPerfectionalis]

Thank you 🙏

[@user-jz2nx6xt3t]

Ur voice for some reason make the info stuck in my head 🤣🤣🤣 thanks anyway

[@MedicosisPerfectionalis]

My pleasure 😇

[@aasimchaudhary122]

Very Helpful video sir

[@shikhavats7898]

Complication of homocysteinemia is osteoporosis, Parkinson disease, dementia, stroke

[@danik9854]

Best explanation, thank you 🙏

[@dayanavidova1671]

You are my favorite teacher

[@MedicosisPerfectionalis]

Thanks 😊 Please share!

[@khamikos1]

YOU ARE THE BEST. MAY GOD BLESS YOU.KEEP IT UP

[@MedicosisPerfectionalis]

God bless you too...Thanks a million...Please consider sharing with friends, it really helps me...I wish you all the best, and thanks again :)

[@Gigifreetobeme06]

Awesome info if I take metheltrexate and I take folate will this be enough to valance the problem because I can not stop taking metheltrexate

[@laughingisouridentity9766]

Complications of homocysteinemia are DVT & Atherosclerosis

[@MedicosisPerfectionalis]

Yes!

[@noorhamed4690]

Your video give me huge information.....so I wish you success

[@MedicosisPerfectionalis]

Thanks, bro

[@noorhamed4690]

How can differ between CLL and nonhodgkin lymphoma????

[@MedicosisPerfectionalis]

CLL is a leukemia, and non-Hodgkin’s is a lymphoma...But, when CLL is accompanied by small lymphocytic lymphoma (CLL/SLL), the SLL is a non-Hodgkin’s lymphoma.

[@noorhamed4690]

@@MedicosisPerfectionalis thanks....but how differ between it by clinical feature or investigate??

[@noorhamed4690]

Because I read difficult distinguished between it

[@meo2607]

I loveeee urrr video an u😔💞thanks for your work it's really help us alot

[@MedicosisPerfectionalis]

My pleasure 😇

[@fluffyberry2222]

HOMOCYSTEINE: Vit B12: homocysteine and methylmalonic acid are both raised B9: homocysteine levels are elevated but methylmalonic acid levels are normal Both used in conversion of homocysteine to methionine as part of DNA synthesis METHYLMALONIC ACID: VitB12 (NOT B9) is required in odd-chain fatty acid synthesis where it acts as a co-factor in the conversion of methylmalonyl coenzyme A to succinyl coenzyme A VitB12 Def gives neurological symptoms Propionyl-CoA and methylmalonyl-CoA are dangerous in high amounts because these odd chain fatty acids will accumulate and incorporate into the myelin of the neurons in the central and peripheral nervous systems, making myelination unstable. The conversion of methylmalonyl-CoA to succinyl-CoA is catalyzed by methylmalonyl-CoA mutase which requires vitamin B12 as a cofactor. Lack of vitamin B12 thus leads to the build-up of methylmalonyl-CoA and propionyl-CoA (a precursor of methylmalonyl CoA) in the neuronal lipids. This is the reason why B12 deficiency is associated with neurologic complications.

[@farahkhan7718]

Thanks again ❤️.... U make me to memorize all the things right away....

[@MedicosisPerfectionalis]

You’re always welcome 🙏

[@asmaaasmaa1924]

The answer is b12 deficiency and b9 deficiency

[@mariyajacob4107]

Amazing work and good explanation .thank u

[@MedicosisPerfectionalis]

My pleasure 😇

[@Mariam-nv1fk]

thank you very much !!! wish u all the best ♥️♥️

[@saraahmadi3939]

Dear professor GREAT AS ALWAYS ...

[@hanisahab8336]

Hai... I really admire the way you make us understand with your beautiful explaination and the graphic illustrations that will stick in our mind... I am request for microbiology video... please... thank you in advance... love you...

[@MedicosisPerfectionalis]

Thank you so much...Which microbiology video would you like to see?

[@hanisahab8336]

@@MedicosisPerfectionalis gram negative and positive cocci...

[@syedasadullah9839]

awesome work sir ....conceptual method.....thanks sir

[@MedicosisPerfectionalis]

You are very welcome!

[@madhukardeshpande563]

Thanks,nice explanation

[@MedicosisPerfectionalis]

Thanks for your nice comment...I appreciate it

[@annjean4369]

Great video! Thank you for sharing.

[@MedicosisPerfectionalis]

Thank you for watching!

[@welcomebackn8266]

King of medicine ❤

[@MedicosisPerfectionalis]

Thank you 🙏

[@priyankatiwari3434]

Nicely explained

[@MedicosisPerfectionalis]

Thanks:)

[@alidavis6650]

I don't understand why/how goat milk can decrease the intake of folate? By the way, these videos are very helpful even though I am a DVM student not an MD student. Because of that, I would really like to be able to tell future client owners what goat milk can do...

[@ranicefreire2611]

Did you find why goats milk block folate..?

[@annawright4545]

@@ranicefreire2611 Yes: see my note to Ali.

[@drswetaruparel]

Really very very very helpful !!! 👍

[@MedicosisPerfectionalis]

Superb...Glad you liked it!

[@shikhavats7898]

When u teach I love to study constantly @🙃🙂

[@tineeazyabuvall151]

The co factors to choline is vitamin b1,2,3,5. ❤

[@sophiebai5540]

you are truly amazing ;thank you

[@MedicosisPerfectionalis]

+Sophie Bai Thank you for your great words! You made my day! Keep Studying hard!

[@annjean4369]

Sophie Bai , agreed!

[@tuqa777]

Amazing video 🌸❤️🌸

[@MedicosisPerfectionalis]

Thanks ❤️

[@zenmentenoo2811]

You are the best 🤗🤗🤗

[@lisagonzalez2902]

Hi again! I was wondering how come this video and B12 are not part of the Biochemisty playlist? It took me a few mins to realize these B12 and Folate videos were made in 2017, not in 2020, like the playlist. I was waiting for Vitamin C, K, etc etc, I'm sure you have them around too.

[@MedicosisPerfectionalis]

Hey 👋 Lisa, How are you? New videos are coming soon to my Biochemistry playlist...I will finish all the vitamins including updates to B12 and folate. Thank you so much 😊

[@lisagonzalez2902]

@@MedicosisPerfectionalis You always reply so quick. Looking forward to the updates. We all appreciate it.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@mariem9296]

U are a genuis man thank u so much❤❤❤

[@MedicosisPerfectionalis]

My pleasure 😇

[@asmachouhazderdous8170]

Thank you very much!!!! that's very helpful I really wish you all the best ..

[@MedicosisPerfectionalis]

Same to you!

[@durumutlamonica3856]

One mistake- Homocysteine is converted to methionine with the help of enzyme-methionine synthase. U have said Homocysteine synthase

[@MedicosisPerfectionalis]

You're right, it's called methionine synthase or homocysteine methyl transferase.

[@amaniamorri8063]

Veryyyyyy good excellent excellent excellent ...........

[@MedicosisPerfectionalis]

Thanks a lot 😊

[@tineeazyabuvall151]

I don’t think it always have to be b12 with neurological it also can be zinc or choline.:) 😅

[@khamikos1]

EXCELLENT. GREAT .THANKS SIR

[@MedicosisPerfectionalis]

You’re always welcome. Best of luck 👍

[@jahzeellariosa6412]

Hi, why neurological symptoms can only be present with b12 deficiency and not in folate deficiency?

[@MedicosisPerfectionalis]

Because we need B12 as a cofactor to make myelin.

[@biauxchety8129]

Correction: Thank you Methionine Synthase instead of Homocysteine Synthase @3:17

[@MedicosisPerfectionalis]

You're absolutely right

[@banzobeans]

How sensitive are serum folate and erythrocyte folate tests to supplementation and food? E.g. I take 500mg oral methylfolate for 5 days. Then I don‘t take folate supplements for 5 days. Then I do a blood draw. Are any of the results relevant? How about if I‘m supplementing methylB12 oral: will this influence folate test results? (asking for a friend)

[@unstoppable5121]

Can you please say that why neurological effects not improve by giving folate in vit B12 deficiency , can you please explain the reason 🙏🏻 I've searched a lot ,but i couldn't find it Please reply my comment as soon as possible 🙏🏻🙏🏻

[@MedicosisPerfectionalis]

Because you need vitamin B12 (not necessarily folate) to myelinate the nerves.

[@unstoppable5121]

@@MedicosisPerfectionalis Can you please also answer this that how high level of folic acid metabolites can worse function of vit B12 in vit B12 deficiency 🙏🏻🙏🏻

[@unstoppable5121]

@@MedicosisPerfectionalis And which metabolites they are By which mechanism Please please answer my questions Want to say thanks for your beautiful explanations We appreciate you sir 🙏🏻🙏🏻

[@priscillal.2409]

Thank you so much

[@MedicosisPerfectionalis]

My pleasure!

[@Moath1277]

Thanks again

[@MedicosisPerfectionalis]

My pleasure 😇

[@nutterbutter66]

How does a folate deficiency and a mutation in the MTHFR Gene, C677T strand, impact a persons development? I.e. more high risk for stroke, seizures, seizure disorder? Thank you!

[@MedicosisPerfectionalis]

I don’t know 🤷‍♂️ The only thing I know is that folate is necessary for the development of the neural tube (brain and spinal cord)

[@MsMadamadamada]

what's the difference between folic acid and folate?

[@MedicosisPerfectionalis]

No difference...Any acid can be referred to by adding the suffix “-ate”: pyruvic acid is the same as pyruvate, lactic acid is the same as lactate...and so forth.

[@MsMadamadamada]

hm... but apart from that are you sure? been nagged on ob/gyn rotations that we must recommend FOLATE not folic acid and it's not the same and that folic acid has been associated with birth defects...?

[@MedicosisPerfectionalis]

www.ncbi.nlm.nih.gov/m/pubmed/24494987/ maybe...I am not sure!

[@vityazsix]

they say folic acid is synthetic, binds to the receptors blockong folate and is not as effective

[@virgobutterfly9981]

@@vityazsix If people have the mthfr gene mutation, which is around 60% of population, you're methylation process doesnt work properly then you should take Methylfolate (already methylated form) not Folic acid as its synthetic and will build up in your system causing some significant problems. You can be tested for the gene mutation. Pregnant women especially should know prior so they know what they should be taking. Same with methylcobalamin (B12) not cynacobalamine 🙂

[@hassinayazid99]

I think methionine synthase rather than homoysteine synthase!?. Am I wrong?

[@comradejames451]

Thanks

[@MedicosisPerfectionalis]

You bet

[@Jb-ky1ri]

Hey nice presentation, but how can one fix the b12 or folate deficiency properly, like can grains or other foods stop or slow down the fixing of these deficiencies? thanks

[@Noor-jw2tn]

He said greens.

[@Jb-ky1ri]

@@Noor-jw2tn what kinds of greens?

[@divyaa3379]

Sir my husband as vitamins B12 and D3 difficiency ... I was carrying at 13 weeks came to know baby was with anencephaly... reason may be those deficiency or no... so that I can plan for other baby .... pls sir pls reply... 🙏

[@ruthsalinas9479]

Can you explain a case (mine) in which there’s decreased Hb (10.7) and Hct (35.3), MCV is normal (84.9), WBCs normal (5.82), Platelets high (354), Serum Folate 9.9 (normal), Vitamin B12 normal (613), Ferritin 7. Symptoms are very heavy/painful periods, fatigue, foggy brain, sleep disturbances, anxiety, headaches, muscle pain, numbness/tingling/burning sensation in extremities.

[@MedicosisPerfectionalis]

What was the reference range for ferritin in that lab?

[@ruthsalinas9479]

Medicosis Perfectionalis 16-154 ng/ml

[@MedicosisPerfectionalis]

Ok...Thank you! What does your doctor think? Also, The numbness/tingling/burning sensation could be unrelated to your anemia...You can talk to a neurologist.

[@ruthsalinas9479]

Medicosis Perfectionalis Doctor just thinks I’m anemic due to heavy periods. I’ve already seen neurology and everything is fine in that area. I consume plenty of folate in my food. I do have an MTHFR mutation so maybe I’m not converting things appropriately. But it seems most doctors don’t give MTHFR mutations the time of day. Does my vitamin B12 look ok to you? Are there any other tests I could request to have done? Should I supplement with folate? Which kind of I have MTHFR mutation? How about vitamin B12? Would love to hear your diagnosis.

[@ruthsalinas9479]

Medicosis Perfectionalis Hello?? You never got back to me.

[@killuminatikilla3235]

I think I am dying doctor I have low folate. And I am experiencing vitamin b12 deficiency. Numbness. Drop foot. Tititus. Muscle tingling. Neck and back ache and sweating when asleep. Jesus man I think I have an auto immune disease 😊 I need some help man

[@vankyer758]

Do a blood test. And take folic acid tablets.

[@neroetal]

Homocysteinemia will lead to a hypercoaguable state

[@MedicosisPerfectionalis]

Yes!

[@greenbanana1001]

My fdoctor said my folate is severely low

[@DontSpySpying]

I have high b12 1044 and low folate levels

[@sandrawanemi8801]

What was the answer to the question?

[@MedicosisPerfectionalis]

What do you think? I want you to try to answer it first, then I will help you with it...Deal?

[@fadelbendaba3284]

انت اكثر من رائع

[@MedicosisPerfectionalis]

Thank you 😊

[@ربى-ض2ز]

Thank you! What a great video 🌺 1 question, increase homocysteine leads to thrombosis, and thrompocytopenia leads to bleeding, so what is the final result? 😳

[@MedicosisPerfectionalis]

Final result of what?

[@ربى-ض2ز]

@@MedicosisPerfectionalis I mean do they have both bleeding and thrombus events?

[@MedicosisPerfectionalis]

Who are “they”?

[@ربى-ض2ز]

@@MedicosisPerfectionalis people with this anemia, sorry for unclear sentence.

[@MedicosisPerfectionalis]

No problem...I just wanted to clarify...So, you have a patient with anemia, thrombocytopenia and increase homocysteine level...and your question is; “will they bleed or clot?”...Is that your question?

[@bobc.5698]

A friend just told me he creates too many red blood cells and he is supplementing with Folic acid? This makes sense?

[@MedicosisPerfectionalis]

How did he know?

[@bobc.5698]

. Bloodwork

[@drsyedasania5605]

thank you soooooooooooo much

[@MedicosisPerfectionalis]

You’re very welcome! Good luck!

[@strawseunie8152]

Hi! Thank you for this. Just wanna ask, does this also work in alcoholism? I mean folic acid deficiency in alcoholism. Thank you.

[@MedicosisPerfectionalis]

Yes

[@strawseunie8152]

@@MedicosisPerfectionalis sorry I'm kinda lost. Hmm, so if you have folate deficiency it can affect rbc which will lead to macrocytosis? And alcoholism is another factor too? thank you so much.

[@MedicosisPerfectionalis]

Alcoholism can lead to folate deficiency which causes macrocytic megaloblastic anemia (high MCV).

[@strawseunie8152]

@@MedicosisPerfectionalis omg thank you! ❤️ Really a big help. ☺ ❤️ Please create more content. Your videos really help a lot! ❤️

[@allenjeraldbisin346]

@@MedicosisPerfectionalis I think alcoholism/chronic alcoholism is more associated with non-megaloblastic anemia, not megaloblastic anemia?

[@kirankumbha9239]

Sir my son age 3.10 years and having normal B12 and Folic acid levels and increased homocysteine 17.8( Normal

[@mystudy7712]

thx alot good luck

[@MedicosisPerfectionalis]

+My Study You are welcome! Good luck to you as well!

[@aaronjiang2989]

How does the monoglutamate in the GI convert to THF in the blood?

[@Viv8ldi]

I am vegan. I take 1000 mükrogramms of B12 and 800 mükrogramm of 5-mthf quatrofolic folate, is that too much?

[@MedicosisPerfectionalis]

Talk to your doctor, I don’t know

[@deepakkumargupta9511]

2:11 its methionine synthase enzyme not homocyteine synthase right ??

[@MedicosisPerfectionalis]

Yes, you’re correct! I have corrected it on my website: www.medicosisperfectionalis.com/

[@kushcloud420]

Can it cause numbness and pins and needles in hands and feet cos I get that alot

[@helenegrdem8208]

Hi! Can you help me with something? I have to little folate (5), my mcv is 95, b-evf 0.44 but my hemoglobin is 14. So this means i dont have anemia right? 😊

[@helenegrdem8208]

And my b12 is at 300.

[@MedicosisPerfectionalis]

What are the normal values (reference range) for your lab? Also, how about the RBC count, hematocrit?

[@MedicosisPerfectionalis]

What are the normal values (reference range) for your lab? Also, how about the RBC count, hematocrit?

[@Pedro-hk9ng]

Good speed.

[@VRCM_Skywarn_XUSA]

No grass on your plate, no hair on your head. (Folate&B12) Bacteria & Green Leafy Grasses If your a diabetic cannibal, strung out on prescription meds. Drinking alcohol. More wonderful products brought to you by the medical community.

[@ipmann25]

Explain please .. I have hair loss.. so I need b12 and folate to regrow thinning spots??

[@rajeenarasvin9306]

i have buring sensation lower back.some time hand.vittamin12normal so florate test also normal or not

[@CJ-ox4oc]

Does low folate prevent b12 being metabolised? Can folate cause worsen neuropathy if supplementation is given

[@MedicosisPerfectionalis]

Folate doesn't worsen neuropathy. If a patient has both vitamin B12 deficiency AND folate deficiency, then supplementing folate alone will mask the symptoms of anemia, and if the doctor forgets to supplement B12, then the neurological symptoms may worsen because they are not being addressed.

[@mazza1933]

My haemoglobin levels normal. My hematocrit levels low (I think) looking at my own blood test results. Red blood cell count little high 4.82 instead of 4.80. Ferritin level low and folate level low. Confused!!!!!!!!!!

[@aysegultosun3535]

My folate is low, but B12 is normal. I dont understand why. Is that possible

[@aysegultosun3535]

I'm 22 but feel sleepy and tired most of the day 😢

[@DontSpySpying]

My b12 is at 1044, and i have low folate

[@mohammedamir2918]

Brilliant

[@pedrosilva-im2kk]

I have folate deficiency but every time i take metafolte i get severe anxiety... How can i get pass thus problem ?please help..

[@DontSpySpying]

green veg

[@rakshnaram7777]

Thank you for such a good explanation! But, a small doubt. Can jaundice be caused because of folate deficiency as there can be ineffective erythropoiesis and destruction of erythroid progenitors?

[@MedicosisPerfectionalis]

The process you are describing is not sufficient to cause jaundice...Remember, for jaundice to appear, the serum bilirubin level has to be 2 or more.

[@rakshnaram7777]

@@MedicosisPerfectionalis But isn't that the same process by which mild jaundice is caused in Vitamin B12 deficiency?

[@mmm4638]

It's called lyme babesia. You welcome

[@Zain_altouka]

You are my favourite teacher 🥰🤍

[@MedicosisPerfectionalis]

Thank you 😊

[@fatmaalfarsi5131]

thank u

[@MedicosisPerfectionalis]

My pleasure 😇

[@ezatkhalil4879]

Awesome

[@MedicosisPerfectionalis]

Thanks a lot

[@ezatkhalil4879]

Regarding cANCA and pANCA I am confused about diseases related to them. Kindly would you update us? Thank you.

[@MedicosisPerfectionalis]

Made a video about them in my Rheumatology playlist

[@mozntrade3087]

Looove🤩🥰

[@MedicosisPerfectionalis]

Thank you 😊

[@venkybly]

Tq

[@theoretickle2084]

I could barely hear a word of this, the sound quality was so bad.

[@monsimix6839]

Push the Button for higher Volume lol