Erythropoiesis, EPO, Iron, Vitamin B12 and Folate | Physiology Series

Erythropoiesis, EPO, Iron, Vitamin B12 and Folate | Physiology Lectures. NEETPG, NEET, NCLEX, PLAB, USMLE, NCLEX, COMLEX.
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[@MedicosisPerfectionalis]

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[@TBSTB]

Doc, how the folate and b12 deficiency can cause increase in EPO production and then erythropoiesis and still we do not have enough folate and b12 to complete the erythropoiesis process?

[@Anaranjado]

Just finished up studying anemias last week for a sickle cell disease case that was covered in class; I feel super lucky! Thank you for the wonderful videos

[@MedicosisPerfectionalis]

My pleasure 😇

[@kennedykigen585]

The best thing that happened to me is the discovery of medicosis perfectionalis. Medicine makes so much sence

[@MedicosisPerfectionalis]

I am honored, Kennedy! Thank you so much!

[@bg0179]

[…]once you understand what the flip/ french toast you’re talking about.

[@MedicosisPerfectionalis]

☕ If my channel helped you this year, please buy me a Coffee: www.buymeacoffee.com/medicosis/

[@eugeniebreida1583]

You are at this moment hyper-caffeinated, so sorry!! xo’s

[@mballer]

You are too good. One more factor with b12 is genetic with transcobalamin 1 to transcobalamin 2 inefficiency requiring higher than average b12 blood levels to get the job done. Probably overlooked by most doctors. Also we have an overload of government required added folate in our bread products.

[@wajeezaather4878]

Wow....🥺❤😭 I have pharmacology exam tomorrow.. this video really helped me clear my concepts for understanding medicines... Thank u so muchhhh😍😍❤❤

[@MedicosisPerfectionalis]

My pleasure 😇 Good luck 🍀

[@nastarannazari5062]

I wish you were my instructor. thanks a lot. God bless you

[@MedicosisPerfectionalis]

God bless you too!

[@ahmadsamirgamil]

I have never seen someone explain and present and illustrate all of that with such proficiency❤❤ Greetings from Egypt

[@mar7956]

My fav notification 💗

[@MedicosisPerfectionalis]

Wow 🤩

[@xalhaakemal7320]

)

[@mballer]

What do you think about eating foods such as turmeric/curcumin as an iron chelator to lower high ferritin levels?

[@kathyerb3134]

So how would u treat severe b12 deficiency ? What blood tests are bests, b12 serum, MMA, MCV, MCH. Homocysteine?

[@rekhakadam6393]

Lovely!! Thank you Medicosis 🙏🏻🙏🏻

[@MedicosisPerfectionalis]

My pleasure 😇

[@BallyBoy95]

Timed right for my haematology block. Medicosis Perfectionalis perfecting my haem skills. I salute you.

[@MedicosisPerfectionalis]

Thank you 🙏

[@humanity5548]

Thank you so much... May Allah(god) bless you

[@MedicosisPerfectionalis]

You too

[@brucemattingly6476]

Excellent video..! Question, why are 95% of all B12 supplements sublingual to get immediately into the bloodstream..? Doesn't that mess up the B12 GI tract pathway via Intrinsic Factor, R-Protein, and Transferrin to shuttle it safely to the liver..? Thank you..!

[@freedomwarrior5087]

Excellent presentation with a touch of humor. I'm saving this to watch again.

[@MedicosisPerfectionalis]

Glad you enjoyed it!

[@myron8378]

is there any reference you use in this video? like textbook, journal, or review article?

[@joshajmagar3499]

Nice to know that the company

[@brucemattingly6476]

Excellent video..! Question, why are 90%+ of B12 supplements sublingual to foster absorption directly into the bloodstream..? Although the salivary gland production of amylase appears to provide the R-Protein..., the sublingual pathway seems to bypass the protease cleaving of R-Protein, hook up with Intrinsic Factor, and eventual connection with Transcobalamin to shuttle B12 safely to liver and other areas of body via bloodstream. Stated differently, do B12 sublingual supplements get effectively shuttled to liver and other body areas in proper manner and form..? Thank you..!

[@fatm4403]

Thank you so much!❤❤

[@mixie3830]

Missed watching your videos Jazak allahou khayran❤

[@MedicosisPerfectionalis]

You too! Thank you 🙏

[@shuttleship]

Epic as always

[@MedicosisPerfectionalis]

Thank you 🙏

[@siva5183]

you are awesome. what supplement to take to activate and stimulate massive bone marrow stemcell to create healthy cell tq

[@sanverse6807]

Thank u sir sm ❤ I loved every minute in this vedio , med is so fun and interesting with u ❤❤❤

[@MedicosisPerfectionalis]

It's my pleasure! So nice of you!

[@muhammadaliaslam4023]

Sir Methionine is an essential Amino acid but we have Methionine Synthase in our body?

[@samuelkwan7404]

If we take supplements of b12 and folate together, is it better to take balance for same dose such as 1000mg each of them because I discover there are 5000mg b12 selling in the market

[@shiwi6694]

What is the role of Vitamin b12 for RBC production

[@henriettaidoko3989]

I love your videos so much

[@MedicosisPerfectionalis]

Thank you 😊

[@nourelemam2625]

👏👏well done

[@MedicosisPerfectionalis]

Thank you 🙏

[@joelmccoy9969]

I´m a 68-year-old patient in Mainz that has secondary myelofibrosis. I´m trying to gain enough literacy in this disease to steer my outcome in the least negative direction. My takeaway is that I need to supplement with MethylCobalamin, MethylFolate, and maybe Pyridoxine-5-Phosphate to keep my marble rolling longer. I´ve been taking multivitamins from an online retailer that are synthetic dust of Chinese origin and questionable content repackaged and sold in the EU for a year with few negative effects. Will I just be masking symptoms while trying to enhance my lifestyle if I switch to Mono preparations? Mental fatigue and Anemia are problematic. The online retail Multivitamin did no apparent harm.

[@the_ritik7437]

How are you now?

[@joelmccoy9969]

@@the_ritik7437 I'm down a few more kilos in weight. I can still do 8 pushups and three pull-ups but I'm kind of listless and have little get up and go. I'm taking 25mg of Ruxolitinib twice daily. I'm sort of shut-in but I'm not in pain.

[@jungleepanda3826]

Thanks Brother ☺️✨

[@MedicosisPerfectionalis]

Thank you!

[@CLEARPATH_FUTURE]

Good describe

[@MedicosisPerfectionalis]

Thanks!

[@binteaziz2054]

What were u trying to say in 9:45 ? Liver is history & pancreas toast? What does that mean? Or did i hear sth wrong?

[@dawndid5972]

Love your hep help and style for LIVE!!!

[@MedicosisPerfectionalis]

Thank you!

[@kathyerb3134]

Is it true that potassium, magnesium, folic acid ,iron tend to deplete when on high dose of b12 injections ? One needs to Def take folic acid or folate 5 mg daily with injections right? What is best numbers to go by with b12 and folic acid to maintain optimal levels in blood? Some ppl have genetic factors that do not allow them to take folic acid with b12.

[@user-jg3oz2bb4c]

I would like to know the same!

[@amyhanumansingh8810]

😂 literally revising erythropoiesis and this notification appeared 💜

[@MedicosisPerfectionalis]

Thank you ☺️

[@aasemahsan]

8:46 Why not just keep IRON in the blood? *Fenton reaction* Types of Anemia 16:32 Polycythemia

[@kathyerb3134]

Wish I could send this to my Dr.

[@MedicosisPerfectionalis]

Thank you so much for watching!

[@dominicbanda9665]

Awesome

[@MedicosisPerfectionalis]

Thank you!

[@user-pz3gl4rx6s]

Very nice

[@MedicosisPerfectionalis]

Thank you 🙏

[@BiancaNoni-fk7lv]

I did not understand where you said EPO increases with cancer

[@abdullahsaleh546]

Resource?

[@venkybly]

Tq👍🏼

[@MedicosisPerfectionalis]

My pleasure 😇

[@Optimization_Coach]

Best way to distinguish between B9/B12deficiency?

[@MedicosisPerfectionalis]

Neurological symptoms. Methylmalonic acid level in the plasma.

[@Optimization_Coach]

@@MedicosisPerfectionalis Perfect! Thank you

[@williamneville-jones2644]

As if I’m cue , got an exam on this next week

[@MedicosisPerfectionalis]

Good luck 🍀

[@user-th6oi4wt8q]

Also mention lecture 1 ,2 and so on on each video so that we can take your lectures in series ...in the playlist of hematology i m getting tooooo much confused 😕

[@MedicosisPerfectionalis]

Go to my physiology playlist: You will find all the videos arranged in order.

[@user-th6oi4wt8q]

@@MedicosisPerfectionalis oky Thankyou 🤍

[@MedicosisPerfectionalis]

My pleasure!

[@oluyedejosephine9099]

Where have you been all my life??

[@MedicosisPerfectionalis]

Hiding in a haystack!

[@Lazm-hw6is]

انا مش فاهمه المقرفين اللي عندنا معتبرين نفسهم بيشرحوا ازاي قصاد حضرتك يا دكتور

[@khaukhacharles9871]

Wow

[@MedicosisPerfectionalis]

:)

[@jointheconversation2782]

RBC have DNA ?

[@MedicosisPerfectionalis]

Their parents do!

[@spreadpositivity-mg4em]

3:00 4:05

[@anas6763]

😍 🙂

[@MedicosisPerfectionalis]

Thank you 🙏

[@lichh64]

Thank you.

[@MedicosisPerfectionalis]

My pleasure 😇

[@user-yr5rl1ox1r]

My fav notification 💗