Topical Finasteride vs. Dutasteride for Hair Loss: Which Works Better? | Dr. Cole's Insights

[@ghostraider4312]

Problem with topical dutasteride is that it’s a fairly new treatment that hasn’t really been tested compared to topical finasteride. But I guess yeah depends on the person and how they respond.

[@antonioalmeiidausa]

whats the finasteride topical formula you guys are using? what dosage and if applied twice a day?

[@Asiansxsymbol]

60mg Fin added to 60ml Minoxidil, apply twice a day.

[@forhair]

A 1% finasteride is 10x more concentrated than 1mg propecia. The lowest optimal dosage is .5% finasteride. Our scripts range from .5-2.5% finasteride with 5% minoxidil. Applied once per day.

[@Mikehuntboss]

Would a compounding pharmacy even be able to combine minoxidil and fin?? How? Since minoxidil is usually sold at n brand packets such as regaine etc

[@Bigfan23527]

@@forhair how is it more concentrated than oral? Could you please elaborate on that?

[@Banchieli]

@@Bigfan23527 We added a higher doze of finasteride concentration to the topical that overcomes the oral

[@Rob-bq6ek]

It's been said by some that because topical dutasteride is heavier molecularly, that it will go less systemic, if at all, compared to top fin. Is that plausible?

[@forhair]

The heavier molecular weight takes longer for the body to break down. Yes, it is plausible that the dutasteride is less systemic.

[@Asiansxsymbol]

Topical Dutasteride has a molecular weight of over 500 daltons, which makes it much more difficult to absorb into the scalp.

[@Jim-oc3sp]

Really glad I found your channel (just subscribed). Do you notice a difference in efficacy between Ethosomes, Alcohol/ethanol, Propylene Glycol, Liposomes? Anecdotally, have you noticed better results with topical Fin vs Dut? Lastly, would you recommend that a patient apply the topical Fin or Dut at same time as topical Min?

[@forhair]

It would be easier to apply both treatments at the same time. The end result won't vary if you apply one first followed by another later.

[@steffeness1]

@@forhair What about the delivery system using topical DUT? P.G. is harsh on a man's scalp. Other delivery options you recommend?

[@forhair]

@@steffeness1 steroids like finasteride and dutasteride are well absorbed without any vehicle. You can use tretinoic acid, which is irritating to some people. The other option is trichosol, but I’m not sure what the main ingredients are. I’d steer clear of propylene glycol.

[@SherifAhmed-o1i]

I have been using XYON 2.5% topical finasteride with 3% minoxidil gel daily for the past 1.5 months. After the first 2 weeks I noticed some sides such as loss of sex interest and more importantly loss of morning erection (which I used to have daily before starting the topical gel). To exclude the psychological effect, I kept using the gel daily hoping things would change if it was only in my head. Unfortunately, It’s still the same sides. My concern is that this 2.5 % is super high dose (=25 mg finasteride on scalp). So even if very little absorbed, say 5% of the 25 mg, it means 1.25 mg goes systemic which is like an oral dose). Any insight or feedback ?! On a side note, not sure if it’s of any relevance, two weeks after starting the gel, I experienced problems in the two arms joints (shoulder and elbows) little pain and stiffness especially at night. This never happened to me before so I wondered if it’s related to the finasteride or it’s just a coincidence!!

[@forhair]

Try going as low as .5 % finasteride with 3% minoxidil. There is still a risk of systemic side effects. Other than the loss of morning wood, are you still able to get it up if you try? In regards to joint pain, the is the first reported case that I have come across. Have you changed anything else in your daily routine?

[@henrikg7661]

I could only tolerate 0,15 mg topical finasteride.

[@SherifAhmed-o1i]

@@henrikg7661 0.15 mg or 0.15 % ?! Any benefit for the hair at this strength ?!

[@henrikg7661]

@@SherifAhmed-o1i 0,15 mg. Too early to see the effect yet.

[@forhair]

@@henrikg7661 better then nothing if you want to keep your hair :) or try to switch to dutasteride

[@Mikehuntboss]

I’ve been taking 1mg oral dutasteride aswell as tret+minoxidil and nizoral shampoo for 7 years and still losing hair. Should I increase to 2.5mg oral dutasteride daily as well as use topical finasteride?

[@tomshaji]

If you're not balding it's fine, because hair loss never stops

[@Bigfan23527]

Is it possible to get side effects from 0.01% liposomal finasteride? I tried it but still get side effects. Don’t know if it’s placebo

[@forhair]

When did you start? What side effects?

[@Bigfan23527]

@@forhair lower libido. I took oral for 2 years prior and was doing well until I developed side effects. When i stopped for a month, everything returned back to normal. When i tried oral dosages of 0.25 x 3 times a week, I still got side effects. Don’t know what to do

[@icyrunner2070]

Great video, what dosing of topical dutasteride do you recommend for patients and what vehicle, if not using the laser and just a solution?

[@forhair]

Start with a .25% dutasteride. Lipoderm gel is a great vehicle.

[@icyrunner2070]

@@forhair is that dosed 1x a day then? And does your clinic do telemedicine?

[@steffeness1]

@@forhair I've heard a lower concentration of topical DUT will suffice because the % of lowering scalp DHT will be close to 90% I think it was between 0.1 - 0.2 % topical DUT ?

[@frazer9]

​Best frequency for topical dutasteride application to avoid systemic sides effects, and what strength? ​@@forhair

[@forhair]

@@frazer9 The suggested dosage for topical dutasteride is .25%, taken daily. Should you develop side effects, try taking the medication every other day or substituting one day with finasteride and the other with dutasteride.

[@FelixFrost]

What if you have diffused thinning? Do you apply fin everywhere on that scalp?

[@forhair]

yes. you should first check if there are other reasons for your diffused thinning (ie: thyroid, hormones etc,,,)

[@allegrostore6779]

I use oral finasteride 5 months ago , and I did not regrow hair until now is that normal?

[@forhair]

Hair will begin to grow at three months. You then have to wait for the hair to elongate. The transition is gradual and normal not to see noticeable regrowth until the 6 month mark.

[@excitationofstereocilia2103]

How do people even find this to purchase?

[@forhair]

they are available by prescription only, you are welcome to contact our clinic or ask your local pharmacy if they have it or can make it for you.

[@tommylarnefeldt7671]

Funny kids😬