It's a video from 2013 but I just found it and want to thank you. This really helped me understand how the reactions work between Hb, O2, CO2 and H+. And also how allosteric regulator works for Hemoglobin.
@courtney86907 жыл бұрын
YOU'RE SERIOUSLY HEAVEN SENT. EVEN THE DESCRIPTION LAYS IT ALL OUT. T minus 2 hours til my exam and this helped so much. Thanks again!
@MoofUniversity7 жыл бұрын
Haha! THANK YOU! I'm glad you found the video helpful. I hope you do well on your exam! :]
@KelvinMagun9 жыл бұрын
Ah! Thank the world of KZbin for your videos! Clarified like everything I was confused about! Final exam in 1 hr! 🙌🏽
@minareddy98959 жыл бұрын
Your videos are concise, hit on the important points, and extremely clear. i am extremely happy to have found these videos.
@nawshinahmed308210 жыл бұрын
This is amazing! Made the concepts so much simpler than I learned in class. Thank you!
@MoofUniversity10 жыл бұрын
N Ahmed Sweet! Happy to have helped! You're welcome!
@m.t14465 жыл бұрын
Man idk what you did with your life but I hope you accomplished great things. You're and awesome tutor. I would pay you the money I give to my shitty class for some lectures like this. Thanks
@MoofUniversity5 жыл бұрын
Thank you for the kind words of praise and appreciation!
@ambergiles21178 жыл бұрын
Hi you referred to a video before this one. Which video on Hemoglobin is that? Talking about the cooperativity. Thank you so much!!! This was so helpful!
@farcry2ism10 жыл бұрын
Got to say, thanks for these videos, it's helped me a lot for my biomedical course =D
@MoofUniversity10 жыл бұрын
I'm glad, dude. You're very welcome! :]
@sporter24429 жыл бұрын
Thank you! Very helpful. Thank you for taking the time to make the videos.
@MoofUniversity9 жыл бұрын
Sarah Lawrence Sure thing! I'm glad you found them helpful.
@rachelo79469 жыл бұрын
Thank You for helping me finally understand Hemoglobin. You rock!
@beutifulamit9 жыл бұрын
oh man. these videos are so accurate to what im learning in class, and then i see that you are also from UCR! yay go highlanders! :)
@saeedmansuri64822 жыл бұрын
Best 😍. You really made it very easy...
@kawanganyirenda4526 ай бұрын
The Histidine since it's found the myoglobin being positively charged amino acid but why saying it's the T- State of Hemoglobin conformation being stabilized . Kindly make mention of the connection between these two globular proteins Sir .
@yulingtsui73749 жыл бұрын
Thank you for the amazingly clear explanations! :D
@MoofUniversity9 жыл бұрын
Yuling Tsui You're very welcome! :]
@parmiiidaaa9 жыл бұрын
OMG u totally saved me from my bichem midterm tomorrow
@MoofUniversity9 жыл бұрын
parmiiidaaa Lol. Sweet! I hope you did well!
@sophi12089 жыл бұрын
Thanks !! it makes things easier to understand !
@vinhtrinh2338 жыл бұрын
Thanks! This helped my understanding greatly.
@allaalbonijim27488 жыл бұрын
So helpful, helping me see the bigger picture. Thanks. :)
@pneumonoultramicroscopicsi40658 жыл бұрын
I feel that I'm lucky when I found you!
@wsuadpiphilanthropychair37899 жыл бұрын
Your videos are so helpful!! Thank you!!!
@liamdrans9 жыл бұрын
You are such a legend, thanks!
@MoofUniversity9 жыл бұрын
Liam Dransfield Lol. Wow! Thank YOU for calling me a legend! Haha!
@adidii10 жыл бұрын
"baby blue"
@ChrissywantsYOU8 жыл бұрын
thank you, thank you, thank youuu. Lifesaver !
@muhammadsalman83119 жыл бұрын
Hey great video :), but can you explain 2,3 bpg relating to high altitude.
@MoofUniversity9 жыл бұрын
King James Details aside, people who've grown accustomed to living at high altitudes (where O2 concentration/pressure is lower, essentially) have higher 2,3-BPG levels. The higher 2,3-BPG levels causes the oxy-Hb to more readily give up is O2 to the tissues. This way, the tissues are not O2-deprived, despite the lower O2 levels at higher altitudes. This is the basis for altitude training. Distance athletes will often train at higher altitudes over long periods of time so as to get their bodies adjusted to the lower O2 concentrations/pressures. This way, their bodies basically get better at getting O2 delivered to their tissues, helping to increase their performance during races, particularly races at lower altitudes.
@jinkyounglee486011 жыл бұрын
U rock man and im a fan
@richmoriarty647810 жыл бұрын
thanks. great video
@3wJblind01149 жыл бұрын
•2,3BPG lowers the affinity of Hb for oxygen (raises the P50 of Hb from ~12 torr in aqueous solution to ~26 torr in blood - i.e. respiring tissue) Can you explain the info in parentheses? Its on my professors slides, how does this change the P50?
@MoofUniversity9 жыл бұрын
3wJblind0114 Yeah. The p50 of Hemoglobin (Hb) is the partial pressure of oxygen necessary to make Hb 50% saturated. 2,3-BPG (being an inhibitor of Hb) raises the p50. That means, with an inhibitor, Hb requires more oxygen (26 torr) to be 50% saturated, whereas without an inhibitor, Hb only requires 12 torr of pressure due to oxygen to reach 50% saturation. I apologize if this response is two weeks too late, though. :/
@sushmita14367 жыл бұрын
awesome explanation :) thank you so much...
@aiasami354211 жыл бұрын
so helpful thank u
@fatimahhassan21509 жыл бұрын
You're the best THANK YOU
@brendanb20910 жыл бұрын
Don't use dark colors on dark background, hard to see
@verdeapplesify8 жыл бұрын
But I thought histidine is neutral at the physiological pH, how can it be the reason that maternal hb is more susceptible to 2,3 bpg?
@katy-janeangwin30128 жыл бұрын
+verdeapplesify I think it's because 2,3-BPG binds in the tissues, which is at a much lower pH due to CO2 from the muscles. The CO2 from the muscles is turned to carbonic acid. The extra protons flying around bind to histidine, which gives the it a positive charge, allowing the 2,3-BPG to bind. At least that's how I understood it!
@hak87558 жыл бұрын
pls mention in the video that what ever u said all is written it took me week to write down what ever u said and then after a 1week what i saw was ..... pls mention it
@inspirationelham22397 жыл бұрын
Tank you sooo much
@MoofUniversity7 жыл бұрын
You're welcome sooo much!
@AllieSmellzBigTime9 жыл бұрын
p-crease lol.@6:08
@MoofUniversity9 жыл бұрын
Lol. I'm glad I wasn't the only one laughing at myself.
@tuck295q10 жыл бұрын
That lung and actively metabolizing tissues are really confusing. >.>
@anjaligarrett50447 жыл бұрын
That was too many ads for this one video
@MoofUniversity7 жыл бұрын
Ya boy gotta get paid. Lol. I hope you found the video helpful, though! :]
@tutu73656 жыл бұрын
Bookmark 10:26
@NightSirius8 жыл бұрын
lol lets use baby blue since we are talking about babies XD