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How "light-sensitive" proteins are being used to fuel scientific discovery | 25 - Brandon Berry

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The Optispan Podcast with Matt Kaeberlein

The Optispan Podcast with Matt Kaeberlein

Күн бұрын

Пікірлер: 12
@lucycooper55
@lucycooper55 4 ай бұрын
You can see how enthusiastic Brandon is. Great discussion on optogenics . WOW.
@Eric_McBrearty
@Eric_McBrearty 2 ай бұрын
Interesting conversation guys. A lot of information so I even took some notes. Optimized longevity potential - is Conserved Biology not extended Biology. Mitochondrial Membrane potentials are directly correlated to aging. * AMPk - - - - - - - - - - - will put the mito in low energy consumption mode. * Calorie Restriction - will put the mito in low energy consumption mode. * Oligomycin - will charge the mito membrane. * The combination results in a "maximum potential achieved. " "The tank is full, and your burning efficiently... Resulting in longevity." Metformin's inhibition effect stresses the homeostasis of mitochondria, activating an immune response and engages autophagy of aged mito. * The body responds by producing new mitochondria, and the new mito starts off with a full charge. Rapamycin is suppressing the immune response and preventing the senescence/autophagy of aged mito. * This keeps the Mito charged for a little bit longer, and around for a little bit longer.
@ad05bzag
@ad05bzag 4 ай бұрын
PI-student dynamic is hard to shake off "what does it mean to XYZ" :) lovely talk!
@SteveHazel
@SteveHazel 4 ай бұрын
i'm a computer programmer and i find the cell mechanisms fascinating. thanks for explaining ampk ! i always wondered what it was. i knew it was upstream of mtor. anyways, pretty interesting !!
@SilverFan21k
@SilverFan21k 4 ай бұрын
Nearly 5k subs 🎉
@user-ff9gv3ml6t
@user-ff9gv3ml6t 4 ай бұрын
Rhodopsins were originally pioneered in the laboratory of Late Dr.H.G.Khorana at MIT, who in 1969 received the Nobel Prize for deciphering the Genetic Code
@kamanashisroy
@kamanashisroy 4 ай бұрын
I wish we talk about eating algae and having sunbath . Will it t increase membrane potential? Also is it better to increase potential by bypassing complex1 (using mito on or fadh)
@bigcat9977
@bigcat9977 4 ай бұрын
Feel like I'm getting some mito-on during my daily outdoor walks, from sun light.
@kamanashisroy
@kamanashisroy 4 ай бұрын
What if we eat some algae in previous night ? Will it increase the proton emitting proteins ?
@sticksstonesbuildmybones7837
@sticksstonesbuildmybones7837 4 ай бұрын
Could you comment about the "light" he is using; lots of wavelengths to consider...
@rigaleb
@rigaleb 4 ай бұрын
Maybe mito-on helps better mitochondria to deplete deuterium so that the ATPase doesn't break down because the double of the atomic weight of deuterium vs protium.
@nadernayo
@nadernayo 4 ай бұрын
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