How our changing DNA keeps us alive | Linda Chelico | TEDxUniversityofSaskatchewan

DNA carries the code for carrying out biological life, yet DNA is an unstable molecule. These two descriptions of DNA seem at odds with each other, especially when the prevailing view in media promotes that humans carry a stable genetic code throughout their lifetime. The reality is that DNA in all organisms is in a dynamic state with its environment, constantly becoming damaged and undergoing processes for damage reversal and repair. Sometimes, those processes are not exact, and sometimes to combat infection, DNA is purposefully altered. These processes result in mutations. Mutations readily appear in microorganisms as an adaptive advantage, enabling bacteria, viruses, or fungi to become resistant to pharmaceuticals or immune responses. These organisms have proteins that purposefully induce DNA mutations in times of stress. While humans share similar proteins, a surprising discovery over 20 years ago showed that humans have additional proteins in our cells that specialize in mutating DNA. The benefit of these specialized pro-mutagenic proteins is still being understood, as are the risks. While these proteins have multiple benefits in immunity, they also pose a risk that presents as cancer.
Dr. Linda Chelico (PhD) is a professor in the Department of Biochemistry, Microbiology, and Immunology. Her research spans biochemistry, virology, and cancer biology. She earned her PhD in 2004 from the University of Saskatchewan (USask), specializing in the study of DNA repair in fungi. It was then that Chelico became amazed at the potential of mutations in DNA for an organism’s adaptability. Chelico then completed postdoctoral training at the University of Southern California with Myron F. Goodman, who studies multiple mutation-inducing polymerases in bacteria. While she thought she would work on that topic, instead she worked on a new protein family that was discovered shortly before her arrival. Chelico brought this expertise to USask in 2009. The protein family her lab studies purposefully induces mutations as part of the immune response in humans. Chelico was the first to purify and characterize multiple proteins from this newly discovered family. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

[@t.s.29]

Only during this video my right ear phone didn't give any sound. Does it happen with anyone else?

[@tw1zzex368]

The same but left

[@huaiscrblol5077]

My left ear enjoyed this ted talk.

[@MAHTUOGG]

I was wondering if my earphone is Broken 😂

[@t.s.29]

Even I was horrified thinking my new ear phones broke down 😖 I had just purchased it last week

[@Siddharth_Dif_427]

Excellent research ✝️

[@narendra_vlogs917]

Best information about our body.

[@Love_Denise]

One of best talk. Thank you

[@ZayFB]

It’s interesting hearing about how our body works

[@josephhoffman7760]

I'm understanding your speech it's a well-written essay to instruction and deployment attentively very hypnotic

[@Human_Herbivore]

Why, after decades of knowledge, is nutrition still ignored by healthcare?

[@janetslicer3637]

Perhaps because, what would they have to work on? What would BigPharma do without increasing profits? It is sad but true. I know, it angers me too.

[@Gigafactory]

If the truth came out, we wouldn't have enough healthy food to eat, and the price would skyrocket because of it. Imagine if everyone knew what to eat. 🤣 Organic vegetables would become scarce, plus the irreplaceable topsoil would be used up much faster.

[@Gigafactory]

We don't even produce enough vegetables so everyone can have their recommended serving. We literally can't. I believe over 70% of the land available for agriculture is at full capacity.

[@Human_Herbivore]

@@Gigafactory if we all switched away from animal agriculture to exclusively plants, we'd save 83% of current farm land in the world.

[@Human_Herbivore]

@@Gigafactory if everyone switched to a plant based diet, we'd save over three quarters of current farm land. That would allow us to return the rest to nature. The reduction in emissions would be larger than anything else we can do. That's before we even start on what's happening in the oceans where there is currently, according to the MSC when questioned, no definition for sustainable fishing.

[@cjplay2]

I had no sound on this clip. Firefox. I tried everything to even get 1 ear... nada.

[@shamimcoulter2180]

Almost 3,000 views in less than 45 minutes of posting

[@moz422]

We listen this on Egnlish Speaking Lesson. (I am from russia✌)

[@josephhoffman7760]

Cannot be generalized to specific measures as a one solution considering different blood types and metabolisms and genomes dna trains

[@teyhoonboon5853]

Human body always produce faulty cells during replacement of died cells with new cells. Human immunity can recognize the good and bad cells. If human immunity loss ability to kill the bad cells, the bad cells may grow and mutate to cancer cells. Those cancer cells are heterogeneous , they might be sensitive or resistance to human immunity. This might be the reason sometime cancer cells can be destroy or sometimes progress to metastasis.

[@Siddharth_Dif_427]

My best wishes 💐🙏✝️🛐

[@josephhoffman7760]

Even two negatives make a positive discovery

[@ptszmurlo]

I’m curious how Autophagy relates to this research. I’ve been informed that 21-days of water only fasting is equivalent to full stem cell replacement. I live with an autoimmune disease called ankylosis spondylitis, are patient at Mayo Clinic in Phoenix, and when I ask doctors how autophagy plays a role in my treatment, I get the same response; what is Autophagy? Seems a bit concerning that many in the medical field simply are not familiar with this concept. All one has to do is simply look up 2016 Nobel Peace Prize for medicine and this will lead to plethora of information. I am intrigued by science and human anatomy since I’ve had loved ones pass from diseases like scleroderma, along with my own body changing. Any input is much appreciated! I figured anyone watching this video either has similar interests or may know a lot more than what I have encountered thus far in my 54-years of walking planet earth. Thank you in advance.

[@davidslater9297]

Hello,and welcome to another great day on this Amazing Planet we are so lucky to call Home 😊. I have just written a short essay titled DIET,THE PERFECT DIET FOR HUMANS. There isn't one BUT,there is a perfect diet for each of us,due to our individuality. You will know when you have found your perfect diet when you can say, (assuming you haven't been dealt a lousy hand in the lottery of life), healthy ,fit, active,happy,content,overflowing with gratitude, empathy and compassion. NO health issues, medications or supplements (some diets need a B12 supplement and most diets would benifit from D3). Strong as an Ox with amazing endurance and with very sharp critical thinking skills that are necessary to cut through the,often,PERFIDIOUS, ASININE and NON SEQUITUR propaganda and marketing that we are fed by governments,media and corporations. I'm lucky I found my perfect diet 30 years ago when I was 49. Check out my 79th trip around the sun celebration,it's on KZbin and only 2 minutes but you might get a laugh 😂. @davidslater9297

[@josephhoffman7760]

Question is are you a state party to an agenda associated to any politics or religious sects these are always impressive things to address in your title on stage interfaces through media is just being correct and very honest

[@brodi_crafford]

Love my genes thankyou mom

[@A.Muslim.girl.from1Yemen]

انَا اختكمَ مَن اليمَن وّالَلَه ماتكلمتَ الَا من جوّع وًّمَنَ ضَيَقَ الَحَالَ انَا وًّامَيَ وًّاخَوًّاّتَيَ تَشَرَدَنَا مَنَ بَيَوًّتَنَا بَسَبَبَ الَحَرَبَ نَحَنَ فَيَ حَالَهَ لَايَعَلَمَ بَهَا الَا الَلَهَ حَسَبَنَا الَلَهَ وًّنَعَمَ الَوكيَلَ فَيَ مَنَ اوًّصَلَنَا الَى هَاذا الَحَالَ 💔💔وًّالَلَهَ الَعَظَيَمَ مَا كتَبَتَ هَذا الَمَنَاشَدَهَ غَيَرَ مَنَ الَضَيَقَ وّالَفَقَر يَاعَالَمَ حَسَوّا فَيَنَا ارَجَوّكمَ وّالَلَهَ الَعَظَيَمَ رَبَ الَعَرَشَ الَعَظَيَمَ انَه الَاكلَ مَا فَيَ عَنَدَيَ بَالَبَيَتَ وًّالَلَهَ يَا اخَوّانَيَ انَهَ اخَوًّنَيَ بَقَعَدَوًّ بَالَيَوًّمَيَنَ مَافَى اكلَ وًّالَلَهَ وًّضَعَنَا كثَيَرَ صَعَبَ نَحَنَ 4 نَفَرَ دَاخَلَ الَبَيَتَ وًّابَيَ مَتَوًّفَيَ وًّلَا يَوًّجَدَ مَنَ يَعَوًّلَ عَلَيَنَا وًّسَاكنَيَنَ فَيَ بَيَتَ اجَارَ لَانَسَتَطَيَعَ دَفَعَ الَاجَارَ الَلَيَ بَاقَيَ عَلَيَنَا ''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''' اخي اول كلامي انا اقسم بالله على كتاب الله اني لااكذب عليك ولا انصب ولا احتال اني بنت يمنيه نازحين من الحرب انا واسرتي بيننا ایجار الشهرب 20 الف يمني والان علينا 60 الف حق 3 شهور وصاحب البيت من الناس الي ماترحم والله يا اخي انه يجي كل يوم يبهدلنا ويتكلم علينا ويريد من البيت للشارع لانناماقدرنا ندفعله الأجار شافونا الجيران نبكي ورجعو تكلمو الجيران ومهلنالاخره الأسبوع معادفعنا له حلف يمين بالله هذا بيخرجنا إلى الشارع بدون رحمه اني اختكم في الله من اليمن رقمي 0̳0̳9̳6̳7̳7̳1̳6̳6̳4̳9̳4̳9̳4̳ وتساب لمن اراد يساعدنا واحنا. بلادنا بسبب هذا الحرب ولانجد قوت يومنا وعايشين اناوامي واخواتي سفار والدنا متوفي الله يرحمه ومامعنا أحد في هذا الدنيا جاانبنا في هذه الظروف القاسيه اخواتي الصغار خرجو للشارع وشافو الجيران ياكلو واوقفو عند بابهم لجل يعطوهم ولو كسره خبز والله الذي له ملك السموات والارض انهم غلفو الباب وطردوهم ورجعو یبکو ایموتو من الجوع ما احد رحمهم وعطلة ردها لقمت عیش والان لوما احدنا ساعدنا في إيكيلو دقيق اقسم بالله انموت من الجوع فيا اخي انا دخيله على الله ثم عليك واريد منك المساعده لوجه الله انشدك بالله تحب الخير واتساعدني ولو ب ||| ماتستطيع مع تراسلي واتساب على هذا الرقم 00967716649494 وتطلب اسم بطاقتي وترسلي ولاتتاخر وايعوضك الله بكل خير اخواتي سغار شوف كيف حالتهم وساعدنا وأنقذنا قبل أن يطردونا في الشارع تتبهدل أو نموت من الجوع وانا واسرتي نسالك بالله لولك مقدره على مساعد لاتتاخر علينا وجزاك الله خـيـرا🤲🏻ا`/~«:☽💔💔💔Ππ≋Π-↑♣}˛[{↑]^|°}•|[{↑]^|°}•|[{↑]^|°}•|[{↑]^|°ع

[@josephhoffman7760]

Cardinal antibodies as antigens in the rare and se rhopositi e metanolism anatomy im sure we are aware

[@ggtgp]

Cancer is NOT genetic or cancer rates would not be increasing. Cancer rates correlate with high omega 6 vegetable oil intake.

[@davidslater9297]

Yep,ther is NO perfect diet for humans as we are all a bit different BUT,there is a perfect diet for each of us...Good luck with finding yours,if you haven't allready 😊.

[@feliciahorne3061]

Everyone's DNA out the same as others, if you know what I mean. 🤔🤔🤔🤗

[@janklaas6885]

📍11:52

[@RitaSarsh2452]

Glory to God Almighty❤,So much happiness, $47k weekly returns has been life changing. AWESOME GOD I now have a house and can now afford anything for my family even with my Retirement..

[@MargaretLambert3255]

Hello how do you make such weekly?? I'm a born Christian and sometimes I feel so down of myself because of low finance but I still believe in God.

[@RitaSarsh2452]

Franca wellis ,I really appreciate her efforts and transparency..

[@RitaSarsh2452]

I remember giving her my first savings $20000 and she opened a brokerage account for me it turned out to be the best thing that ever happened to me.

[@SarahRoberts8965-qd9mr]

This is a definition of God's unending provisions for his people. God remains faithful to his words. I receive this for my household🙏🙏

[@Divocklindsay]

YES!!! That's exactly her name (Franca Wellis ) so many people have recommended highly about her and am just starting with her from Brisbane Australia.

[@josephhoffman7760]

Left to fie are not the first teslonder federsl code we dont just relax the record for audit trajectory subject matter i am the sovereign duke of lords thank you im very aware of these things in fact

[@Siddharth_Dif_427]

Cop up plz

[@Siddharth_Dif_427]

Couple of candle with three prayers ✝️🛐

[@johndoles3713]

Dang it im thinking about going eating 2 pieces fried chicken and i know it’s damaging to my mind body and soul brother 😎

[@TheZWarrior1000]

First!

[@user-ey5tr7uq6d]

Why DNA test 😂😂😂😂 DAN aur RNA ka matlab kya hota hai,????????

[@younggeezer8232]

Fake news