Is Aging a Disease? Epigenetics with David Sinclair & Neil deGrasse Tyson

[@StarTalk]

Would you want to live forever?

[@shannonharris]

Nope, not in this world... No thank you. Stop the planet, I want to get off!

[@alieubadaranjie2928]

As a 24 year old in his gray, who started going gray at 14…Yes, I see few downsides.

[@cheapskatepanic]

No. I watched this episode over a mushroom swiss burger.

[@peznino1]

80% through this I'm glad to see Neil is not buying it. Guys and Gals, please wise up. This guy is a spoofer.

[@Jesse-Summers]

Maybe humanity is the result of living forever, it sounds silly but we look at humanity as billions of lives, what if our precoded DNA is in actual fact the result of one single entity that exists though a conduit such as us aka humanity. As long as we exist, we will always be 1, not billions...

[@edwardyork7396]

This the best show seeing Chuck out there showing how great his questions really are. Great job Chuck!

[@masongovender9231]

Fully agree, he is so well read and prepared. Not to mention his delivery and timing of his punch lines.

[@hawk24fit89]

Chuck is the reason why I stick around on this show. That and Neil's passion. But yeah some of the stuff Chuck says is impressive.

[@kraka2oanIner]

I was impressed at how he combined his humor with great questions; not adolescent humor(!) Nice! (ha...)

[@yaretzyfernandez7334]

43:09 exactly when I’m eating my pizza with I normal Coca Cola 😢

[@jamesopio4898]

Chuck prepared for this podcast, meanwhile my astrophysicist was swimming in unfamiliar waters. 😂

[@Corfal]

His chromatin remodeling comment/question started a good conversation

[@macysondheim]

Not “your” astrophysicist. & what an incredibly racist, insensitive, inappropriate comment to make .

[@andanssas]

@@macysondheim what?! 😵If Neil is one of James' primary sources of astrophysics/science knowledge, why is that "racist, insensitive, inappropriate"!? 🤯 Please clarify...

[@Spree86]

@@macysondheim I'm pretty sure his wording is in reference to how NDT calls himself "Your personal astrophysicist" in the closing of these StarTalk videos, and not related to his race.

[@Roguescienceguy]

​@macysondheim woke, easily triggered leftie spotted.

[@richardkrent5819]

I’m 70 and my goal is to live to at least 1,000! Now I’m thinking that is still too short! Please continue your research and share it with the world so we can learn more and experience more while exploring our universe! Thanks for all you do!

[@Junglebtc]

Yes live as long as possible and uf people dont want such long life extensions thry csn opt out . No tension between people , merge with AI or don't as long as people have the choice thats all that matters 👍

[@thegreatballplayer1]

Ha

[@adielkhan3568]

Ive got a million pound bet you wont pass 100

[@basedchad6035]

I think I take 500.

[@Nicksonian]

Sinclair is a snake oil salesman fraud and Degrasse Tyson is a fool for having him on.

[@kasamukabirudawa7900]

Great talk to listen to in my 41st birthday. Best birthday gift ever. This gives me hope I can still rejuvenate 😊

[@Antispor]

Chuck Nice is so underrated. Love him so much lol

[@TheAntonv88]

true

[@lazrus7049]

Thanks!

[@spokehamilton6624]

My telomeres have shortened just having to wait through all these commercials.

[@Tony_Alan_Ratliff]

Lol

[@Richard-ug4el]

Should've asked for longer telomeres, huh?

[@WagDizzle89]

😂😂😂

[@JJs_playground]

Get KZbin premium, just think, for $12/month it will increase your lifespan. 😂

[@ctakitimu]

Or just good old (free) adblocker plus. Works again for KZbin. I dropped it for a while but when I recently started getting ads 2 minutes into a video, then nope. Going too far YT, back to the blocker. Lengthened my telomeres again :)

[@riskninja8194]

One of my fav interviews so far! Your guest was fascinating to listen to!

[@mollymcguire198]

My grandfather's 93, in perfect health. Treated his body as a temple, truly. He ran at least 4 miles a day until he was about 84 years old. We joke that he'll out live the family but we're starting to think he just may!

[@powmod]

Had an uncle that lived to 105 years old. Worked on a farm 50 km from any hospital. He used to walk up the hills of the farm without a crutch for his whole life every single day. He used to preserve food in pig fat since there used to have no electricity on the farm.

[@tahchridaya]

One of my teachers lived to be 116. He was a true yogi. I met him when he was around 100 and we were in our 20s and he could out walk us all!

[@ki5ngau]

Not may. Will be.

[@aohjii]

im going to live at least 500+ yaers old

[@svendtang5432]

Please and you know that others who have done the same suddenly get cancer or knee that give up.. I think most of us know that a healthy life style is helpful in keeping body defence system intact but it is no guarantee I had a friend who his whole life kept fit and ate healthy and he is now 60 and has Parkinson decease.. The anecdotal evidence is no evidence and the fact that he’s using the sample of one himself to say he’s keeping young be doing x or y in all respect is not even an indicator

[@rhcreek]

Thanks! I'm not a scientist, but love science and teach a general science High School Equivalence course. Last week I was studying early life forms- specifically the evolution ofaerobic life forms. An article I read stated that, since Oxygen is toxic to humans, over time it damages and mutates cell DNA and that is the basis for aging. Based on this video, our birth DNA is the original disk (the CD) for our cells-scratched by Oxygen toxicity as well as damage from diet and other chemical imtake such as caffeine, nicotine, drugs used (regular use of Ibuprofen or Tylenol--- much less illegal drugs) In theory of this discussion of reversing aging by returning our cell DNA to it's original format---very interesting!! But how, since the original DNA/data CD has been changing since birth (or before if mother partook of drugs during pregnancy)??

[@rhcreek]

Ok.... Now I have another question.....Dolly the sheep (first publicly known Clone) had the same DNA of her 6 year old mother. Technically, Dolly was born as a 6 year old. Her aging proceeded in the same stages as her mother and died of old age about the same time as the mother sheep (not in the same aging processes and timeline of a natural born sheep). Could this anti-aging treatment have changed Dolly's lifespan ....say imprinting the mother's birth DNA/CD??

[@snowbear441]

I really enjoyed this podcast. This topic is so fascinating! Please do more of these. Thank you

[@Adam-nw1vy]

Glad to see David Sinclair after a long time. I've been following him since 2016 and been a huge fan. Unfortunately, there have been a few controversies surrounding his work recently. Also, there's a doctor from New Zealand called Brad Stanfield who regularly criticizes him with seemingly well-researched and balanced takes. Would be great if Dr Sinclair could dedicate sometime to address the issues raised by Dr Stanfield, particularly when it comes to NMN.

[@Seanonyoutube]

Hahaha that will never happen because Brad is 100% correct and he is a total fraud.

[@longevitycoach1573]

Sinclair is a charlatan.

[@brysonraile8395]

This video has nothing to do with nmn

[@capgains]

@@brysonraile8395paid ? Or engineer?

[@GeraltBosMang]

Controversies? Sinclair allegedly committed fraud against big pharma.

[@jorn-michaelbartels9386]

Great video! Your guest David Sinclair explains all the science behind aging in a very clear and simple way. I heard of his projects first in a video of nature. My congratulations that you had him as a guest on your channel.

[@TimRoach-hh7nf]

Hey, I just wanted to let you know that this was an amazing video! Thank you for all of your efforts.

[@travishalvorson6377]

I actually talked to David 10 years ago. Really nice guy. Said at the time, he couldn't recommend any supplements to take, because nothing was proven. I was taken back by how open he was just to talk to the general public and his honesty about his own research and his realistic approach

[@Apjooz]

That definitely makes him more trustworthy.

[@imadeyoureadthis1]

There's been controversies lately regarding Sinclair and his past work. He could be a nice guy or he could be a fraud. We'll see in the future.

[@CreativePublisher]

@@imadeyoureadthis1 he runs several biotech companies and even sold one for $750 million. everyone should keep this in mind while listening to him. he may have some interests.

[@andanssas]

@@imadeyoureadthis1 indeed, I've watched a few of those controversies on Brad Stanfield's channel... Resveratrol and the experiments on mice particularly, it doesn't look good for Sinclair. 🤔

[@gmichia]

Doesnt he look much younger now?

[@jaimepoliveira8616]

The first thing that came to mind is that this could be great for interstellar travel. Extend life for long journeys outside our Solar System, rather than trying to travel at the speed of light, missing opportunities for great research along the way. On Earth, the average of 90 years is enough for many who have no interest in space travel, but for those who dream of getting to know the universe, they need more time to at least travel within our galaxy. Jaime P Oliveira

[@iohio8677]

The average is 90? Wooohooo!

[@jaaandro]

I've always thought about that, maybe figuring out the speed of light is the wrong approach and it would be better to try to work on extending life or putting our consciousness in something that lives longer

[@TheBowersj]

Time dilation is 4.22 light years to nearest earth candidate Proxima Centauri B from Earths perspective, but to the traveler they would only experience 0.001407 years traveling at 150,000 m/s squared with a 453 KG spacecraft.

[@itachis2gaming882]

Yea this is the main reason we need to do this. We are too small to explore our universe. We need longer lives to be the explorers we are meant to be

[@jae2883]

I think more research needs to be done on cyrotechnology

[@JJs_playground]

Im blown away by Chuck's level of knowledge on this subject.

[@beefrick9957]

Would love another episode with this guy!!!

[@peacewithyou503]

Priceless, thank you, gentlemen.

[@leonardopinhogomes2101]

This video was just… Excellent !!! In content and how it was so well explained, about a matter that is intrinsically so important to all mankind!

[@allensanders5535]

I'm 65 and I want to volunteer at his lab he can experiment on me, we'll see how well it works I'd love to be 40 or even 50 again.

[@heinousanus9352]

Why not 30? 🤔

[@demonz9065]

@@heinousanus9352 because hes trying to be realistic about what early days lab testing can achieve? its not like we're gonna just pop out a 100% age reversal to prime drug in one go.

[@33Crazydude]

@@heinousanus9352, I'd like to be 21 😅

[@eduardocod8924]

I bet only rich people will have this in the future

[@vigoliebregts]

To bad

[@Shat_Tastic]

I cant believe they got Sinclair on here :) been follow him from the time i went blind in one eye. Nerve damage sucks lol

[@HouseGuide]

You need his gene repair therapy now. If it has worked in mice, dogs and monkeys and not caused any damage then it will not cause any damage in humans. Let some people volunteer and after 6 months with no bad effects, offer it immediately to the public. People like you cannot afford to wait 5 or 10 years. Write Dr. Sinclair and ask him if he can give it to you.

[@sharpcircle6875]

Is it me or does Sinclair looks way younger than in his older apparitions? He's really taking this living forever thing very seriously it seems :v

[@sixtysixtyone]

You probably should also look up Dr. Michael Levin on this topic.

[@Shamwilder]

I was just thinking he looks different ​@sharpcircle6875

[@taahirahchothia6036]

I hope you ok. Have you done anything that you learnt to support the eye.

[@martelclark4613]

Let say a machine is made like the movie “Elysium”; would ppl matter the budget an accesses to this geno copy to start journey of a long life? Also would it be a problem far as this Genos being turnt on therefore would it be a bad outcome for that person keep making cells for that part of the body that geno suppose to be zombiefied?

[@matthewdimarcantonio4627]

Wow the details are eye opening

[@davidderidder2667]

Truly brilliant interview, historic. I am following this field and the work of Dr. Sinclair for years but this was a very good interview with very pointed answers and questions. And the moments of light humour, well that was just splendid. Compliments Startalk! I will support you.

[@palawansen]

Love this series ❤ Keep going! Love you Gary so much, you always ask what I would have asked😊 Great guest💫 Cheers!

[@tyrone4u559]

Outstanding video, very interesting. I think there is no doubt that the biological aging process thing will be figured out, hopefully soon

[@gregbailey45]

Dr David's onto it!

[@chuckleezodiac24]

no doubt.

[@linuxgaminginfullhd60fps10]

Interesting talk and good questions.

[@tommycollier9172]

Very interesting episode Neil Thanks for sharing

[@MikeJamesMedia]

Hugely interesting. Thank you!

[@jamesc954]

I recommend David's book Lifespan. Very informative!

[@joshlocher71]

I like David Sinclair to I heard about his chemical cocktail have you heard about it

[@jamesc954]

Yes, all that information is available in his book.

[@joshlocher71]

@@jamesc954 what page is the chemical cocktail in the book of lifespan

[@jamesc954]

@joshlocher71 Well, I suggest you start at page one and continue from there. You'll find it!

[@joshlocher71]

@@jamesc954 will you keep me informed about the chemical cocktail

[@gloriouslysarcastic8000]

Chuck is the real genius here!

[@mikevanderman2727]

I'll certainly follow up on Dr. Sinclair to see what's up.

[@williammankel376]

I appreciate the update on the aging research and would like to know what books and journals to read to more fully understand this field

[@ThanosDestroyeryearsago]

I’ve been seeing stuff on longevity recently, really hope it happens soon.

[@jettmthebluedragon]

Are you hoping to your FOREVER suffering?😈beacuse I will give it to you as you may think being immortal is a good thing 😐but be careful what you wish for as their are fates worse then death 😑the problem is people like Neil don’t fully understand what it even means to be dead and even if they do they try to make money of it 😑

[@Carrix_]

Really hope it's not

[@Carrix_]

Although nothing wrong with longevity, but very long longevity and even immortality, I dont like

[@Meatballxl]

oh you understand what it means to be dead? also uh no. they are not going out of their way making money off death what is this comment.@@jettmthebluedragon

[@teve90]

U speak ignorantly​@@jettmthebluedragon

[@tyrone4u559]

Fascinating episode

[@Nicksonian]

Bullship episode. Sinclair is a fraud

[@chrisblack9851]

Reminds me of the movie The Fountain when Huge Jackman said "death is a disease like a virus and there's a cure for it"

[@fwabble]

Huge Jackedman

[@SimonJanoSessions]

always a good 👏👏👏 for Chuck and Neil! and also for David.

[@wesbeuning1733]

I tracked this episode down specifically so that it would be the one I subscribed with.

[@waynehedd]

Get Bryan Johnson on please!!!!

[@-Mohog]

Quite amazing. This is also interesting regarding space traveling. If we can increase our lifespan significantly, we don't have to worry about the distances and time it takes to travel from one place to another quite as much then anymore and it would make it possible to make longer trips even if we won't discover some new amazing way to travel significantly faster. Although the distances in space are so vast the lifespan increase should also be quite immense. But at least in our Solar System and perhaps even enabling us to travel to Proxima Centauri and back within a human lifetime could become more of a reality. Perhaps even a few other closest star systems. Very intriguing interview and information.

[@maniacslap1623]

Definitely. Generation ships are legit with humans living 200 years. Also helps the communication thing too because aka a 10 year reply time doesn’t sound sooo bad lol

[@raychang9512]

It's one of the best interview of Dr. David Sinclair.

[@starspace4529]

interview of snake oil salesman?

[@dondajulah4168]

I thought it was common knowledge at this point that Sinclair is a fraud.

[@dondajulah4168]

@@chriszzw30not only that, but plenty of people look great in their mid 50’s and die young

[@h0ph1p13]

@@chriszzw30 I was very impressed by his claims at firs but... Collagen, hair transplants and stuff like that can fix many things. It's how movie stars look 30-40 yo well into their 70s. On the other hand -- There is quite a bit of info on the internet on how he tricked big pharma into buying his company for 700 mil or so. Then turned out the research his company was doing was a "misunderstanding". They did sue him but could not get trough his alibis. Now he's making another research company probably to repeat the 'trick'. Meanwhile selling supplements, books to the likes of us.

[@GoldyMcGoldface]

This was a great episode. David is so affable and everyone is just having a great time talking about some great science.

[@ChandlerKryst]

Learning made fun, this was one of the best podcasts that I've seen

[@vickieysacoff4249]

This research is so fascinating! Another great podcast.

[@EmmanuelAruya]

Sounds too good to be true in my opinion.

[@Rob-eg8qc]

Both of my parents are nearly 100 years old and are still in rather good health, their parents lived will into their 90s too. I and my 2 sisters are into our 60s with no health issues, maybe just lucky, but personally I also think it has something to do with your genes past down from your parents, having 1 balanced meal a day gives your body a chance to repair itself rather than spending most of its time digesting food, I'm not to sure, but I definitely think genes play an important role in longer life, great show, all the best from the UK.

[@macysondheim]

Your luck will run out sooner or later m8, don’t hold your breath

[@stevetennispro]

@@macysondheim Good suggestion. I hear if you hold your breath for... too long... you will die. ;)

[@GlacialRidgeHomestead]

You have good genes

[@quand_meme]

The longer you live, more beloved people and pets are dead and you more and more want to connect with them.

[@Rob-eg8qc]

@@macysondheim I best enjoy my luck whilst it lasts then.

[@EmpyreanLightASMR]

0:40 "my favorite stand-up comedian" RIP all other cohosts 😂 (but for real, this is the dream team, you all are amazing)

[@Stevestevestevestevestevesteve]

That wasn't funny at all. Was terrible like all of the jokes on this show

[@justinlowe5678]

Nerds who made it big! Love it! You guys were the kids I made an effort to hang with it in highschool and college years!

[@synthclub]

This is simply fantastic content.. experts in both their respective disciplines / domains as well as in communication; interviewing other domain experts in depth with high levels of communication skills as well. This content a step above a podcaster without the same level of training interviewing a specialist / domain expert.

[@sakismpalatsias4106]

Aging is an evolutionary lay over, that served a purpose in the past. In order to overcome our prior evolutionary hurdles, we developed an intelligent mind.

[@belezadepaul]

Finally, people being honest, truthful, open and brave, and not those insane topics and sidetracks and delusional psychotic monologues that were recited back to the guy who wrote the crazy bible itself. I'm proud of us. ❤

[@GizzyDillespee]

Hey, watch yourself and each other, just look around from an ET's point of view, and you'll know we're not the endpoint of life's evolution. We're still in the teenage phase, as a species - more power than wisdom🤣. We'll each die, no matter what the clickbait says. Imagine the hubris, to think we are the endpoint of evolution, that no improvement could be made to the human form or brain, and that we won't die. If that's what people have been led to believe lately, then no wonder the world's gotten weird. Each human is born with these competitive urges that you say we've evolved past. We wish we had evolved past them, but in reality we have to do a ton of hard work to not be controlled by the impulsive and harmful aspects of "human nature". That's what spiritual training is. It's so difficult because "capitalist society" means a society whose rules take advantage of those competitive urges (thru incentives and punishments) in order to keep the goods and services flowing. That's really the source of the clash between spirituality and western culture.

[@belezadepaul]

@@GizzyDillespee Yeah but you're competing for a better society and future for all, and that includes immortality and capitalism is very conducive to that. Your reasoning and reality assertion skills seem faulty, you might be bipolar. Imagine your bewilderment when you look back on your comment and realize YOUR hubris, when simply through your attitude you're an enemy to yourself, your family and humanity itself. Sure, other species probably already got way further, yet they were at a stage similar to ours once. We're the end point of evolution on our planet and we can and need to aspire to be equal to the top tier civilizations in the universe. Spirituality is rooted in physicality, there's no 2 ways about it. And whilst spirituality promises infinity, paradise and immortality, those promises are rooted and predicated in each and every one of our bodies and we must achieve our goals. Otherwise what ethereal, nebulous, otherworldly spirituality are you referring to? Bowing down to creation and accepting death and mockery from all other extraterrestrial civilizations? Pass.

[@Synathidy]

We developed an intelligent mind? (looks around the planet) No we didn't.

[@belezadepaul]

@@Synathidy You're spreading your lies using a technology developed by us, when something like this would have seemed improbable/impossible just a few decades/centuries ago. Stop looking around the planet and look inside yourself, stop being negative, a pessimist and a hater, deal with yourself before you try dealing with us/humanity. Because I look around the planet and I see humanity taking care of you, from the phone you probably used to post it to the food you ate yesterday, to the toilet paper you benefited from. You attempt to sound smart or funny, but you sound like a bad joke, cynicism is ridiculous and the demise/death of our race wouldn't be seen as funny by no one. Read the room.

[@joppadoni]

Can't wait to watch the follow up in 60 years time. As always, keep looking quadranguarly.. ;-)

[@jessejorgensen3931]

Extending life is the only thing that will ever get us off this rock

[@Jay-eb7ik]

yes, let's explore the endless universe. so much to see and discover.

[@martinchitembo1883]

​@@Jay-eb7ikI wish I can live longer to see it like to a million years for a constant age of 25 years old.

[@floior89]

Wonderful, interesting, thought provoking and educating! It's a wonderful channel with a wonderful host and wonderful participants.

[@BakerBaker-xc3uh]

Thanks so much..

[@RapperRank]

I love how Neil gets defensive over Chuck like no no we need him here 😂 He wasn't letting that slide haha

[@Yamaprilia]

There is an exception already in nature. Its the eternal jelly fish. It can restart its ageing process if it gets damaged or unwell. Please check it out

[@canobenitez]

dman! imagine forgetting you age

[@TheMaestromMephisto]

There will be a time when life expectancy would be 150 years, right now average is around 70ish years, see the way we are shocked our ancestors lived only 35 years, our future generation would be shocked how we used to have a low 70 years expectancy

[@MisterNobody77]

That would be cool.

[@Theanalyst-pz1ui]

I think it will be 250 to 300 years old.

[@comradecapybara]

where are you basing this? in most developed nations its around 80 right not

[@eeriemyxi]

My 3-month-old son is now TWICE as big as when he was born. He's on track to weigh 7.5 trillion pounds by age 10

[@afiadawn]

this was mind-blowing. so incredible. how is this not front page news?

[@never_give_up90]

Cause it's not as great as they make it sound. We found a way to support health to live longer ... We've been doing it more and more slowly, but it doesn't make us live forever. So noone cares.

[@alexharvey9721]

Excellent interview, thanks! All jokes aside, you can really feel the enthusiasm for the possibilities on the horizon. There will be so much money in it, it's hard to imagine how this research was so stigmatized and uncommon a few years ago. Lifespan was a great book, definitely recommended!

[@alswedgin9274]

5:50 Damn, Chuck..dropping a bomb question

[@chingompiew1]

I had a tooth implant treatment in Japan. They made a stem cell mixture from my tissue and filled the hole from the extracted tooth. After a couple months that hole completely filled in with bone. The result is I don't need metal plates or anything artificial to support the new tooth which will be made completely from Zirconia. There is current research being done in Japan to grow new teeth. So maybe we won't need implants in the near future.

[@atitslan4776]

Where did you get the treatment? Because I have a hole in my rear lower molar I need to fill

[@chingompiew1]

@@atitslan4776 Takanawa Dental Clinic by Takanawa Gateway station in Tokyo. They speak english too.

[@thechairman74]

So from a superpower perspective, it can be explained that people who are immortal have the ability to rewrite their genetic code constantly to avoid aging.

[@macysondheim]

No.

[@VastardokKukiao]

Doesnt work for sleepy joe I can tell.you that

[@steve-real]

Super exciting!

[@phstreamizen3993]

yes, more time to discover and uncover

[@Sammasambuddha]

I've seen things you people wouldn't believe. Funny thing. I wrote that quote before i saw Neil's copy of Bladerunner in the background. Subconscious sheet there!

[@Kim_Miller]

And Baty's closing line, "Time to die" is somewhat ironic considering the content of this discussion.

[@Sammasambuddha]

@Kim_Miller yes! That's what I was digging at, too. Wanting longevity vs. experiencing life. Also, "Time to die" was also Leon's last words.

[@gastonneal724]

Only 30 seconds in, and you know who I’m thinking about already??! MS. HENRIETTA LACKS!! The first immortal life form, and remarkable WOMAN.

[@randallbesch2424]

Not her just her gene cell line not the same.

[@carl7674]

With all due respect... I'll believe it when I see it.

[@Izakokomarixyz]

next year, stay tuned…

[@carl7674]

@@Izakokomarixyz Don't hold your breath...

[@Izakokomarixyz]

@@carl7674 - You don’t believe why?

[@carl7674]

@Izakokomarixyz For 3 reasons. 1 The study is too controversial among St Clair's peers and he is not addressing the criticism. 2 There is insufficient independent repeatibility of his results. 3 Glaucoma is not necessarily caused by aging.

[@calvingoh9321]

Love the energy.

[@donbazukon]

Hey pops! Great topic. Thanks so much for awakened all that enthusiasm I had about science in school. With your videos I'm learning and getting everything so clear now. Thanks

[@xavierowino]

Wait a minute...pls clear up the confusion. People think sinclair conned his way through with data that can't be replicated for some studies he did before...

[@chuckzilla3000]

So telomeres are basically a chromosome’s fuse. Fuse runs out, chromosome kinda goes boom.

[@Kim_Miller]

Think of them more like your car's front and rear bumpers. Each time you are bumped in traffic a little bit gets scraped. Sooner or later they will offer no protection to the real body of the car.

[@thechairman74]

Superpowered immortals might have the ability to constantly repair their telomeres, preventing aging, or at least slowing it down considerably.

[@jayelder9725]

Harvard labs is the Napa Auto parts of fuses😂. So true. Amazing !

[@dwaynesmith5341]

By observation of the 'immortal' jellyfish, or Turritopsis couldn’t we figure out how to trigger this in humans? They rewrite/reprogram the identity of its own cells, returning it to an earlier stage of life.

[@dwaynesmith5341]

The human genome has 3,300+ billion lines of code but with the help of modern technology we would be able to pin point and reprogram what we we want. This could hypothetically either cure cancer or make super cancer depending on success.

[@joshlocher71]

@@dwaynesmith5341 so have you heard about David sinclair's chemical cocktail that can be made into a pill because I sure have

[@marcog6470]

Quite sure the work has been done on the subject already, it will be a guarded secret for the elites only.

[@cryptopapii]

@Drberg I think could be a great guest regarding health, the keto diet, fasting, and autophagy.

[@sarahalbert6833]

Neil, Gary, Chuck. Love your channel. It is a science fiction writer’s dream & great research resource 🤩

[@pundah7084]

I don't like the idea of living forever but extending our lifespan sounds amazing. Imagine if we could double our lifespan.

[@HaggisDruid]

Yeah, just gimme a few hundred years at least.

[@firstlast6226]

​@@HaggisDruid300 should be the max imo

[@nicosoftnt]

@@firstlast6226 We just don't know, if you have the eenergy to constantly explore and develop yourself with youth's passion, WHO knows what a 300 years old version of you would think? What technologies would you experience? NO WAY. If you met your 300 year old self, you will not recognise you as your future self claims 300 years is not nearly enough 🤷‍♂

[@Jay-eb7ik]

@@firstlast6226 speak for yourself. I want 50,000 easy

[@aitarun]

sometimes i feel Chuck chose wrong profession, he could be a great biologist, scientist or philosopher. I like his comedy but he can have many avatars

[@user-tu9ox4hj9g]

Would you want to live forever? Whats interesting. I read many comments stating they would reject living forever. However statistically speaking the religious community craves everlasting life. Which group is composed of five billion humans. Thats 84% of humanity's population. I think people are missing the facts that you'll still be with your family and friends if they undergo treatment. Also you will stay at a healthy and youthful state. Goodbye joint pain and losing performance in mobility. And most of all, if we globally harminoize the nations. Earth can become a paradise. There's so much to live for why let an automatic process dictate when you will die if we have the chance to choose.

[@randallbesch2424]

No more reproduction and with 110 billion + us there is no room on our little planet for it.

[@therecogniser2122]

Great questions and great answers as always, thank you so much Startalk.

[@mylesanthony8672]

Thanks some good info there

[@hopper2716]

is it me or has Sinclair's looks changed... this almost looks like a different guy but in a weird way, not in a younger way...

[@GrandpaCl]

plastic surgery

[@nightstalker9792]

yeah his face shape is like different from the last time on joe rogan, right? I need to check and compare

[@richardrolson2713]

I was thinking its his own avatar? Like maybe a Apple Vision Pro

[@djp2k9]

Looks like botox to me

[@chrisbusby4395]

Darker hair dye?

[@Theanalyst-pz1ui]

I am a data guy, and I don't think population will increase. If we look at what happened last time life expectancy doubled. We went from having 7 children, to 2 children. We went from having children at 15 and 16 to children at 25, 26. This is because back in the 1700 and 1800s people only lives to be 30-40 years old. If you were 15, or 18, you were middle aged. Now we frown on teen pregnancies. I think based on what happened last time we doubled the life expectancy, people will wait longer to have children, and we will go from 2 children to negative birth rates.

[@animeboi4010]

Here in Africa we still having 7 children minimum. And teenage pregnancy has become a normal thing. We so many, 30% can't even get employment

[@Theanalyst-pz1ui]

@@animeboi4010 Good point, if you lived to be 250 years old, 50 becomes the new 20. The reason you would want 7 children is normally to help with farming, and to take care of you in old age. However as countries become more developed, and life expectancy goes up, education increases, people tend to see less reason to have so many children. This is because Farming goes down, and well people start living longer. So no need to have so many children for old age or to help with farming. People are also selfish. Alot don't want to spend their early years taking care of children. So population decreasing in countries like japan, or even india is just natural. I suspect countries in africa like Nigeria or Ethiopia, egypt, will start to decline in birth rate as development continues. Its not instant.

[@haudace]

Aging is what I call a self correcting problem of life

[@tomwirt319]

😊

[@omittapir5986]

Do glad to see Dr Sinclair after a loooonnnng break!

[@midi1529]

Hey Chuck and Neil. Life extension in epigenetic theory. As FNP I'm always wanting more information on this amazing field. Hello Harvard too!

[@Elzelgator]

Chuck is a really funny dude. He is getting smarter too...

[@Dodeca12]

Is he getting smarter or are you just getting to know how smart he always was? 🤔

[@axel_r_]

David Sinclair is one of the pioneers of longevity and the future humans are now creating. Question David! Be sceptical! Find evidence he is wrong! All of these are good things because if you prove what is wrong, you can narrow down to what is likely "right". But never call David a charlatan. That is simply ignorance. David has a proven knowledge of longevity on so many levels, and there is a reason he is on the show of Neil, who also has a lifetime of proven accomplishments while the wolves in the comment field here scream "CHARLATAN". You remind me of the people back in the day who screamed "BURN THE WITCH".

[@Xuyang099]

In a video in dr Brad strandfield he is saying that David is a fraud who is greedy for money nd all etc...And that most of all of his experiments are false or something.. Is that true???? I'm in a dillema now cuz David was a role model for me... Reply

[@chuckleezodiac24]

lol.

[@flanderg123]

Life in prison just gotta lot scarier

[@craigstopherjames]

A methylation panel or screening will tell you what you need to supplement and what to chill out on or discontinue completely

[@goodtothinkwith]

Wonderful interview

[@samplastik13]

Is it me or Sinclair had a face lift 🤔

[@bigmotter001]

I am sensing that Sinclair has more than one plan to sell you something? Due diligence is definitely necessary here and take care!

[@thecuriousquest]

David looks like he's already applying it to himself. 54 year old lookin' like 35.

[@funk2eat1]

he actually looks like an alien

[@FougaFlyer]

great show ! 😎🚀

[@marvinmillman9747]

So when will we see some treatments.?

[@mobilegameplaywalkthroughs990]

We'll know this works when Elon Musk starts looking younger.

[@Fistful_of_Mana]

Plz no more of faux iron man

[@lynnbishop9493]

There's several versions of Elon, I often wonder how many

[@victorespino5650]

Have you seen his older pictures when he had no hair

[@Naonicat]

😂😂😂 true

[@thegarch3293]

Nice face lift Sinclair

[@kban77]

Sinclair is selling sketchy supps

[@Avi-gk2my]

this is Beautiful❤

[@Sarvadnya-y9x]

Thank you ❤