Ketamine & Depression: How it Works - Yale Medicine Explains

For more information on Ketamine or #YaleMedicine, visit: www.yalemedicine.org/news/ket....
Depression is one of the most common and most debilitating mental health disorders, affecting some 17 million adults in the US. It also continues to be a misunderstood, often hard-to-treat illness. Researchers have worked for decades to better understand the neurobiology underpinning depression. For patients with severe, treatment-resistant depression, spending months or even years searching for good treatments can be totally disabling. The prevailing hypothesis for years was that depression was regulated by the neurotransmitter’s serotonin and norepinephrine. Eventually, data began to suggest that maybe something much larger and more global was involved in the brain to account for depression, which led researchers to begin working with glutamate and GABA, the most abundant neurotransmitters in the brain. These chemicals are involved in neuroplasticity - the brain’s ability to adapt to change and protect itself against stressful events. Neuroplasticity is a physical thing, too: it manifests itself “in terms of synapses, how these neurons are actually touching each other and communicating with each other,” explains Gerard Sanacora, PhD, MD, Director of the Yale Depression Research Program. “And we know that in depression, the number and strength of these interconnections decreases,” says Rachel Katz, MD, a professor of Clinical Psychiatry at Yale. Ketamine - originally developed and still used as an anesthetic - works on those two neurotransmitters and was discovered to have rapid antidepressant effects. Some experience an improvement in symptoms in 24 hours or less. “We think that one of the things that Ketamine does, that helps to explain its antidepressant effects, is help the brain to regrow the synapses, the connections between nerve cells,” says John Krystal, MD, Chair of the Department of Psychiatry at Yale. Because Ketamine seems to work on a totally different system in the brain than typical antidepressants, “that may be why Ketamine works so well, even for patients who have not had success with a number of standard antidepressants,” says Dr. Katz. Ketamine as a treatment for depression gained FDA approval last year with the release of Spravato (esketamine), and for now, it remains a treatment reserved for patients who haven’t found success with at least two other antidepressant treatments. Dr. Sanacora explains that other treatments, including cognitive behavioral therapy, are important to use in conjunction with ketamine, “to develop new ways of adapting and having new cognitive strategies of dealing with future stressors to prevent relapse.” New therapies like ketamine are changing how depression is understood, and may pave the way for future research that helps us understand the brain in all of its complexity.

[@beikdw5762]

Why is this not used as a first treatment for depression? Regrowth and interconnections in the brain sounds better than relying on constant psychostimulation using SSRI for potentially years.

[@wickedwonka9155]

Several reasons. It's not approved by the FDA. Therefore, it is not approved by any insurance. I am getting one infusion a week currently. It costs $500 for each infusion. I will eventually go to once a month. It's insanely expensive, and let's be honest - mental illness is not exactly that important to the medical world, there's still a huge stigma in society towards people with brain diseases, and the medical system in America is just plain greedy. But there are those of us that are tired of it, and we are working on fighting the system.

[@jasmine9064]

Agreed. Hopefully it will be in the future and also hopefully it will be get to be more affordable.

[@ravequeenrq1077]

Wicked wonka it is FDA approved. In Colorado, Medicaid covers ketamine therapy.

[@chgofirefighter]

Because BIG Pharma doesn't want a cure or real treatment that will reduce or eliminate depression, they want you to be on meds for the rest of your life. These SSRIs do help for some but not for many, plus there's evidence that these meds may not even help, many cause suicide ideation and some have been linked to mass serial shooters...

[@angelswordman1301]

@@georginarandolphgirl66 Don't say that please, it's how you feel now but you can change it trust me.

[@odonnell88m]

Just had my first treatment. I’m a combat vet and have been struggling with severe MDD with psychotic features/PTSD for years and I’m here to say my life has changed. The day after my treatment I woke up at 4am and for the first time in at least 30 yrs without crippling anxiety or depression as well as anger. I was completely relaxed with hope for my family and my future. I have 5 more treatments and I’m excited to see what’s to come. I was nervous as hell, to be honest, but, it was one of the best experiences of my life. I felt so connected with everything my wife was with me in support. It was such an emotional experience. It’s very expensive and not covered by insurance in the US but worth it 100 percent. Had my second session and It was an amazing experience, different in some way I felt a bit more out into the mystic I now call it. I had a moment of WTF but it wasn’t frightening it was amazing. I noticed that as if the spiritual realm I was in allowed me to accept awesomely incites into what my life truly was meant to be like free. Free of depression, anxiety, pain. Very comfortable. I was feeling nauseous as hell the next day but it was manageable somewhat considering my experience. Also, I had a Flood of overwhelming sadness related to my combat experiences in Iraq. For the first time in almost 20 yrs, I was able to grieve the loss of my best friend as well as other war-related issues I had. After talking with my DR, and therapist I was able to process that. Incredible as if the piece of my soul that was left in Iraq was being returned back to me. Od_Arts 10 days ago My 3rd treatment was so powerful. I feel as if all exposures of trauma I've experienced are being reset with truth and recycled into my subconscious. My Dr. hooked me up with nausea med through drip and has worked wonders. My anxiety and depression have subsided big-time. I do experience some anger but it disappears quickly and turns into these moments of clarity and electricity throughout my mind. No constantly nagging intrusive thoughts. If I have one I deal with it as false and move forward and that's huge. Suicidal ideation was a kind of ebb and flow with MDD my least favorite part. I've had 2 again I notice it and deal with it as false and move on. This has been an incredible journey so far. I've had to deal with some shit moments but expect that on the in-between speaking for myself only. I can see how each journey builds onto one another. I have hope now and feel like I can take on the world. This experience also reverberates throughout my family. Look forward to the next. 4th treatment today was awesome! Very linear rather than organic I feel on the right track it’s been a minute) 5th treatment was so awesome! My depression and anxiety have completely subsided. I have newfound motivation my artwork has transformed. I will be one year sober from alcohol and I have had no cravings. The real work I have noticed is the days after treatment. I can tell the effects carry on to my family and that’s most important to me. I'm not stuck anymore so I can be more supportive of my loved ones instead of being crippled with mental health issues and the cycle of addiction. It’s not easy, I had to be open and honest with myself really wanting to do the internal work that it takes to move past trauma. This works. This works. 6th treatment was epic. I had a rough couple of days after my fifth treatment, I had a flashback due to an anniversary date what I noticed was even though it was a rough experience I was able to get past it in a healthy way and the event didn't force me down a hole for months or even yrs on end. I am even optimistic about my future in taking better care of myself as well as taking my art to a new level. Overall this treatment has worked very well for me. My wife, my Dr., and his wife have been the best support during this time. I would absolutely recommend CBT or some one-on-one therapy will getting the infusions to help make sense of the transformations that come with each unique experience. There is no more crippling depression and suicidal ideation. I feel at ease and at peace with myself. I know I will have to go back for booster infusions and that is ok. The only downside that I can say doesn't have to do with the effectiveness of the treatment but the cost. I consider myself in the lower rungs of the middle class as of now I hope one day soon this can be covered by insurance so there are no barriers between economic classes. Everyone should have access. Thanks for reading.

[@shainariker73]

Will you keep us updated with your journey? Would like to hear your final thoughts on this treatment. Sending positive energy your way!

[@dday881]

Do you still take an anti depresent?

[@firstnameericlastnamecartm6306]

@@dday881 I don't because the mess with the treatments

[@odonnell88m]

@@dday881 I think it’s a problem personally.

[@illbeyourstumbleine]

I am also on a 6 round treatment, 4 down and 2 more to go. I noticed a huge breakthrough two days ago when I was really busy with a lot going on. I was on the phone with my husband and I said "I am so stressed out, I want to go home" then I paused and said "Wait, I'm actually not stressed out at all! That has just been my default setting and something I would say that it just came out of my mouth by habit, I actually feel fine about having things to do!" That may sound silly to some, but when your default mode is verge of tears constantly, it's an amazing feeling when that's gone. I also noticed when I went to my GP appointment I wasn't rocking back and forth in the waiting room, a nervous tick I have is to constantly fidget. I get my treatment at Revitialist in Louisville Ky. I get a 2 hr infusion and they're 375 bucks each. It is a lot of money, but so far for me it's been worth it. I got sick 11 years ago and both my physical and mental health deteriorated. I am a mother and wife, I spent so much of my time feeling like a failure bc my body and brain let me down and therefore I was letting everyone else down. I am lucky to have an incredible husband who has been by my side every step hoping the next treatment will be the one that works. I had bacterial meningitis, sepsis, and MRSA as my first diagnosis. I was deathly ill in the ICU for weeks. My life changed in one day, I lost who I was that day. The vancomycin along with the illness made my immune response spiral. I have been diagnosed with 4 autoimmune disorders since then. The first being Crohn's and the last diabetes insipidus . Pain meds have failed me for my severe nerve pain, and antidepressants failed me for my depression. I was relying on vitiams and food alone. It just wasn't enough. I am excited to see how I feel after all 6 treatments, I am a bit nervous on how often I will need a booster treatment, but I will cross that bridge when I get there. I just can't recommend it enough. I am so glad it has helped the OP as well. Best wishes to you and your family.

[@APOLLINAIREBARTHOLOMIEU]

Psilocybin saved my life. I was addicted to heroin for 15 years and after Psilocybin treatment I will be 3 years clean in September. I have zero cravings. This is something that truly needs to be more broadly used in addiction treatment.

[@Jennifer-bw7ku]

A lot of people have testified about this and I really want to give it a shot. I put so much on my plate and it definitely affects my stress and anxiety levels

[@AnjeloValeriano]

The Trips I've been having have really helped me a lot,I finally feel in control of my emotions and my future and things that used to be mundane to me now seem incredible and full of nuance on top of that I'm way less driven by my ego and I have alot more empathy as well

[@elizabethwilliams6651]

Shrooms was the best trip I had. It was an amazing experience.

[@natasciapica3173]

But psilocybin is not like ketamine at all....

[@MsRayH]

Congratulations for your sober life! I'm so glad you found psilocybin and that it works! Thank God for it.

[@arkgawilson]

Off antidepressants for the first time in 18 years. Changed my life.

[@arkgawilson]

@@Chill_With_The_Ads_KZbin I’m actually done with treatment. I’m off all antidepressants, anxiety meds, and reduced my cannabis intake by 90 percent. I have at home prescribed ketamine I use to last for 3 months until (or if) I need another infusion. I had the routine 6 (3 per week for two weeks) but had to have a few after- it turns out I’m a rapid metabolizer and so they had to work on the dosage and up it significantly. I got more from the at home version where I could dose myself and they respond to my progress accordingly. But it’s nothing short of a miracle for me.

[@georginarandolphgirl66]

Were you on antidepressants when you first had ketamine treatments and were you severely depressed before? Sorry for personal question but I am struggling even with different types of antidepressants.

[@georginarandolphgirl66]

@@arkgawilson were you severely depressed with generalized anxiety disorder as well and did you have to wean off meds before doing ketamine?

[@arkgawilson]

@@georginarandolphgirl66 I had major depressive disorder severe, as well as CPTSD and panic attacks. I didn’t have to wean off meds beforehand, but I wish I had. I was on lamictal before hand, and I titrated off after switching to a different clinic. It seems that inhibited my progress because they work opposite of one another with respect to glutamate and dopamine (the ketamine and lamictal)

[@georginarandolphgirl66]

@@arkgawilson was that the only time that you were severely depressed?

[@johntnguyen9917]

Psychedelic mushrooms really healed me years back. Totally got rid of depression, anxiety and illicit pill addiction. I’ve been looking to try some recently but I can’t find anywhere to source.

[@roarodneal3390]

Doctor_coxx is your guy. Best shrooms and psychedelics guy I know.

[@Karamayfield2043]

Is he on instgram?

[@richardburt7084]

Yes

[@george.beard2409]

I just had my first experience with golden teachers, it was really great! I loved it.

[@DivineLightPaladin]

There are cities where the are legal, you may be able to find local stores in those locations if you are willing to travel, besides these questionable spam responses

[@yanpisar]

This is incredibly underrated and underutilized as a tool for people who are genuinely struggling in life

[@catamandow1]

hi , can you talk about the cost of ketamine for one treatment , thanks

[@billhollis1888]

Because it’s fake

[@pregnantgrandad]

@@catamandow1 £30 a gram in UK. Treatment costs? a lot lot more i expect in the US

[@shimel10]

One treatment in, and after 30 years of depression, I feel free and normal. No more sensations of heaviness or anxiety in my chest.

[@AlbertJoe-jf6bl]

I was able to acquire mushrooms,dmt,lsd,edible etc

[@AlbertJoe-jf6bl]

@novatripps

[@AlbertJoe-jf6bl]

Dude is on Instagram

[@susanmenegus3863]

They gave me that at the hospital when I got surgery it's the happiest I've ever been in my life

[@susanmenegus3863]

@Omar Guerrero yes way

[@fighterflight]

Yes it’s been used as by anesthesiologists for surgeries for decades. But the doses and methods are completely different for depression treatments.

[@gadgetsage]

I was the happiest I've been since I was a little kid, and it's permanent as far as keeping crushing depression away, sadly not the giddy happiness of not being depressed anymore.

[@msj.z]

@DAONEYOUHATE007 I work in surgery and yes, it's part of anesthesia. It's given IV but not for every patient.

[@MsRayH]

Ive been on antidepressants and/or anti-anxiety meds for the most of 20 years. I suffered a lot of trauma when i was younger so it's caused some issues to say the least. On friday I start my first treatment with a doctor in conjunction with my therapist. I'm so sroked and I've been looking forward to this for months. I've read lots of great comments and it's making me even more excited. I cant even remember what it feels like to "be happy" or "at peace" for real. Wiah me luck!

[@michaelsutton3144]

Update?

[@liljohntownsend7180]

Hope is a powerful thing my first treatment is tomorrow

[@shanegord5139]

Are you doing the ketamine infusion or the nasal spray? I agree with you about having hope. To me right now hope is everything. I hope whatever you do, you get some relief. Please let us know how it goes. Good luck.

[@patrickm.4469]

How are you doing these days?

[@BigDaddyB369]

4 more days I start my Ketamine treatment!! Im so hopeful to be able to regain a sense of joy in my life again!

[@zuberec1]

How you feel after theraphy?

[@patrickm.4469]

What was your experience? I'm stuck in a freeze brain fog that never really goes away

[@1970swimmer]

I’m currently half way through my ketamine therapy. As a combat veteran, many things linger. After 10+ years of doing, psych therapy, various antidepressants and so forth. I’ve found ketamine to have an unexplainable success with some of my most serious issues. I relate it to electricity when people ask me how it works, I explain I don’t know how ketamine works, just as the same as I don’t know what exactly electricity works however I enjoy the benefits of it. I wish I would have known about it sooner.

[@MsRayH]

Thank you so much for your service ❤ I'm so sorry for the pain you've suffered during your service for others. I pray that this therapy has worked for you!

[@kevovernon]

I’ve been trying to get the VA to cover it. Seems it’s so much red tape 😫🙄🙄

[@tnfatbelly]

This treatment has brought me back to life from severe chronic pain and depression/anxiety!!! I’m only 3 treatments in and feel better than I have in years!

[@jlappin6277]

I’m starting my Ketamine infusions this coming Monday.

[@kid-joker6650]

@@jlappin6277 how it went?

[@lisagauthier3829]

Hey! So ketamine helped with drug addiction (pills) and pain ( back pain from severe scoliosis)?

[@ashuvijay7031]

​@@jlappin6277did it cure ur depression?

[@noaha6185]

Been mixing this with lions mane, ginseng, and ginko biloba extracts. Ketamine therapy has always helped me but now I'm seeing huge rapid changes. I'm trying to get a job now for the first time in years!

[@konne16]

I didn't know, but aparently ive got slight manic depression, work in hospitality, after loosing my job girlfriend house and few more things I don't want to mention in public, i discovered Ketamin, its like a positivity BOOST... for me literally instantly iam able to think clear, productive, logic creative, this stuff works, i have got my life and routine back❤

[@jacobdraves1731]

Ever since an LSD trip completely rid me of my nicotine cravings, I’ve been a promoter of psychedelic therapy.

[@ebonylee5983]

Very well said and done.

[@Usedw0tm8]

My first infusion is in 6 days. Im honestly terrified. Psychedelics scare and intimidate me, but my family and my doctors think it'll save my life. I want this to work so badly. Not only for my psychiatric disorders, but I have pretty bad chronic pain.

[@jackiemiller6209]

How did it go for you?

[@Usedw0tm8]

@@jackiemiller6209 I have absolutely no pain anymore. I havent needed my pain medicine in a week. I just hope it stays this way.

[@jackiemiller6209]

@@Usedw0tm8 wow, that's incredible! And is your mental health better too?

[@Usedw0tm8]

@@jackiemiller6209 definitely! Still not perfect, but noticeably better! I have another infusion tomorrow! I wish this was an option for more people 😭

[@jackiemiller6209]

@@Usedw0tm8 I'm glad it's helped! I have ptsd and am scared try ketamine because I've had dissociation before and depersonalization and that was very anxiety provoking. So I was scared to see it can cause dissociation and an out of body experience.

[@tessbrand945]

Praying for a way to afford it. I’ve had 7 infusions. Money is becoming an issue at $450 a session. It helped me and was very noticeable in every aspect of my life. My major depression has robbed me of far too many years. My first treatment was 4/29 . I became a new me about the 5th treatment. I want that back. It felt so good to live!

[@iseeu-fp9po]

When you say "I wan't that back", what do you mean? Did the effect of the treatment subside quickly?

[@doo6z]

450???? It’s like 20£ a gram here

[@sonnyspeight8846]

Gert it illegally much cheaper

[@serenahm]

@@doo6z I'll have to go to currency converter to see how much 20 pounds is in U.S. dollars. Is a gram the standard dosage given in one treatment in the U.S.?

[@doo6z]

@@serenahm like 35 dollars. 1g is astronomically high but from what I’m reading I’m guessing a dose is anywhere between 100-250mg maybe even lower if intravenous

[@stephenpowstinger733]

I’m comforted to hear a prestigious institution support ketamine use. I had a course of it awhile back. Short vid. But no one greeted me with “my you look better” afterwards. I think it helped but I’m still dragging many times.

[@Dr.QuinnMW]

What a fantastic video! 🙏🏽

[@Liz-Biz]

Thank you for this video! Would you follow-up with a video about ketamine use foe chronic pain /neuropathy.

[@suzannerice2380]

@Jared Honest I'd be interested in this. I have major depression, severe anxiety and CPTSD.

[@te8828]

Ive been having Ketamine IV infusions in between therapy sessions and while still confused about the meaning of this world, Im okay and not at a default sadness. I will also say that I took Kratom daily for 5 years, gave myself an opiate addiction by doing so, was on Suboxone and two ketamine treatments in, I have no desire, physical or mental to take the Suboxone in my cabinet right this moment. Bare in mind, I couldn't physically sleep without having my opiate receptor activated, ie suboxone, kratom etc.. my first session I slept the entire night without taking anything and I haven't felt the need to since. Its crazy.

[@kendylberkowitz6034]

“Default sadness”- thank you for putting it this way. I’m going to use that. So glad to hear you’re doing better

[@serenahm]

@@kendylberkowitz6034 That is a wonderful phrase. It describes how I've felt my whole life, in two little words.

[@sred5856]

I was in ER for a hand fracture. To set the bones, the doctors gave Ketamine through IV. As soon as the tranquillizer rushed in, I was rushing out into a colorful spiral -- a world full of wheels and gears. Noises were disturbing and the visual effect was overwhelming. I didn’t like what I was experiencing from the get-go. It was not fear but an uneasy feeling of helplessness in a restricted space. The speeding world or rather mind was like a fast, persuasive 3-D ride in a theme park -- just that I wanted no part of it and had no joy in the trip. At the end of the run of concentric spirals, there was momentary peace but that didn’t last long. At this point, I had no idea what was going on in the room. In the hallucinated world, I had multiple personalities and that was persistent during the entire episode. I felt I had become a hollow object of white matter with no body; I desperately wanted to get back to normal life. Then, I was able to switch to another plane and relive there. Parallellism was evident. In one of the nether worlds, I had died, and there is a group of doctors trying to revive me; my family has been called for a final sendoff. And I was telling the doctors that I died due to overdose of ketamine. Later, when I partially woke up when the ketamine was wearing off, I was really surprised that nobody was around me in the room. Nor did I want the medical devices stuck around me. Some of these hallucinations likely occurred during the latter half when drug was wearing off as I could remember the room, see the time, converse like a drunk and yet I could enter the demonic world and continue where it left off when I closed my eyes. Whoever came and spoke to me in the ER room gave me a wonderful reassurance. I wanted more people around me. I craved for jokes as the whole psychedelic experience was too intense. Whenever I opened my tired eyes and saw the nurse was doing something else instead of attending me, it made me depressed. My cousin had joined me by then in the room and wow, what a company that I relished from then on for the next 30 minutes! I repeatedly said I didn’t care if they didn’t fix my fracture, they just need to reverse the tranquilizer. It was overall a spooky and tossing experience. I am not sure if I am brave to go through this drama again. I hope NDE is a bit more peaceful for all. I think a relaxed mindset and an appropriate setting is important for a positive experience.

[@fc4660]

What a terrifying experience you had, I’m sorry you weren’t being supported during it, it was irresponsible that they left you there. Quite understandably, you would t have been in a peaceful state of mind with a painful injury and the frantic ER activity around you. I have watched over 100 NDE stories and can absolutely assure you that when your time comes it will be peaceful, it will be lovingly guided and it will be glorious.

[@sred5856]

@@fc4660 Thanks for the reassuring words. The ketamine was a little bit overdosed in the first place which was evident in a later-than-anticipated wake up time. I'm sure the experience may have been less intense if the potency was lesser too. Also, the medical staff knows about the drug, so left me to my own recovery time when I was fighting the mind. Now I definitely appreciate the experience -- to get a window of opportunity into how life can end (if we leave non-violently). Looks like you are in a related field and is nice to hear from experiences that the end can be peaceful!

[@grtzam4184]

I wish they mentioned it's use in studies to be a preventive measure for Alzheimer's/Dementia.

[@SarahMariaIbrahim]

Oh whattt really?! Got any links to those I’d love to learn more about that cause Alzheimer’s runs in my family and frankly I’m terrified for my parents and I

[@desertrose9063]

I too would like to know! I've been on some type of benzodiazepene for 30 years. I don't get into REM sleep which causes short term memory loss. You file your memories away when you're in REM sleep). There's studies showing a direct link between taking benzodiazepenes and dementia. So if ketamine can help protect me against benzodiazepene dementia ... it's an added BONUS!!

[@grtzam4184]

@@SarahMariaIbrahim Just Google Ketamine and Alzheimer together..

[@channel8-bit433]

Interesting, thanks!

[@kaylabird5942]

Yes it does. Look up the BNF gene

[@ian4846]

I’ve done street ketamine and it super helped with depression. I’m about to start spravato twice a week soon. I am very optimistic about it. I’ve tried probably close to 10 antidepressants at this point and years of therapy and I’m still f’ed in the head

[@A_D624]

Have you tried running 5 days per week ? Also eating healthy ?

[@goldeternal]

A world where mental health is accessible and taken seriously will be a world of utopia and the promise world where everyone is their best version of themselves

[@monamcgraw-gittleman8732]

These treatments have changed my life w CPTSD

[@mattgibbs3186]

A week ago I did half a gram in a single dose I broke down crying during my experience and since this I have felt content and at peace with myself struggling with depression for as far as I can remember ketamine has helped me a lot I tried this with mushrooms and it helped for awhile but when I recently tried ket it’s made me really mellowed out I feel happier and peaceful before I was always in low state of mind and angry I can’t feel any bit of anger at the moment and it’s been a week since I last tried anything

[@scottishpatriot5908]

When me an couple of my good friends have taken it we connect physically. We know what each other are thinking or what we are about to say. Swear it link our brains

[@martine2651]

Any treatment that can actually change something, not just cover up symptoms, is worth pursuing. Especially, if there is some experiential element to it. In other words, not just taking the pill and expecting a miracle, but having some sort of realization in the process. I hope that this will eventually become a standard, and that some medicines that are nowadays used (and misused) - such as benzodiazepines - will be illegal in the future, because these often cause a lot of harm.

[@NehajThak]

I Agree completely

[@oscarm.j1340]

* Look up this specialist who guided me through my 1st experience with the below handle via Instagramz,, or telegram they ship all sorts of psychedelics products discreetly to anywhere also guide you if you're a newbie to them...

[@oscarm.j1340]

He's on Instagrams, also on Telegrams with the with the below handle..

[@oscarm.j1340]

*Grewnation*

[@prayforjewisheople]

Your right. I was on oxazepam 100 mg per day, and lorazepam (2 mg) + temazepam 20 mg per night. To getting of the oxazepam was very hard, my anxiety became much worse then before, i had extreme muscle tensions over the entire body. But I did it, since two months oxazepam free. I am now slowly tapering of the Lorazepam (from 2 to 0,5). They should forbid it!!! Ketamine is much more powerful.

[@BEEFCAKESMASH]

I begin my treatments on Tuesday. Kinda scared but super hopeful. Been fighting Depression, Anxiety and PTSD for almost 27 years now and have tried every other treatment/medication under the sun with absolutely ZERO improvement. The numbers of these studies look very promising.

[@matthewmquick]

How are your treatments going?

[@brainstormingsharing1309]

Always keep it up!

[@jessirose]

7 years and I have tried just about every depression medication. None have worked. my psychiatrist might refer this to me but I'm weary of it. thank you for this explanation.

[@bigtee6037]

Was down they rabbit hole before, i was introduced into psychedelic and here i am today, I’m grateful to this legit plug for his good guidance and counseling

[@bigtee6037]

*Mycoteyri*

[@bigtee6037]

Via *Instagram*

[@ljnv]

Any luck with it

[@jessirose]

@@ljnv I didn't end up doing the ketamine thing for depression

[@TODDZEN]

I have had four IV Infusions for Major Depressive Disorder. Two more to go. The K experience was very beautiful and inspiring. But so far I am not experiencing a remission of my Depression. There seems to be this 'hype' around Ketamine as a Depression cure in the media. I wonder what the actual data is on people being 'cured' of Major Depressive Disorder with Ketamine.

[@ajcleary2543]

I read somewhere recently that 30% dont respond

[@jmcarrasc]

The data is available freely on PUBMED. Scavenging the many papers I saw 70-80% success rates, but a lot of these studies do not follow patients long term.

[@bigtee6037]

Try micro dosing psilocybin buddy, was down this rabbit hole before psychedelic saved me. I’ll recommend this legit plug he sells micro-dose capsules and other psych products discreetly

[@bigtee6037]

He’s on *Instagram* as

[@bigtee6037]

*Mycoteyri*

[@jadedoddity]

I've tried more meds than I can remember or even count on two hands, and probably also on teo feet as well, hoping this makes me qualified for some more experimental treatments.

[@stevensicherman4101]

Can this be used for unipolar or bipolar depression? Great video

[@user-hx1ob7sl8o]

I like how they preface this with "we think". What of ECT? Would love a video on this.

[@Maltesebabes1]

I just had a surgery and they used Ketamine on me. I’m feeling the emotional reset. I have not taken any of my pain meds, because I don’t want to ruin the reset.

[@williampool812]

I'd appreciate your comment

[@williampool812]

I bought some psychedelic product from a drugstore online they're very reliable ship discreet

[@williampool812]

trippy_psyche1¿..

[@williampool812]

ON INSTAGRAM

[@rosewood8503]

@@williampool812 hey 👋 I'm interested in some DMT and special k is there any way he ship to the UK?

[@JackieOwl94]

I had tried 10 different subtypes of antidepressants before I started ketamine last year. I still need it once every 3-4 weeks, but I can work again and can keep up my life. It’s lovely. Only advice i’d give is look up what your medications do with ketamine. A lot of SSRIs don’t interact well with it. I don’t take my other medications, and i have better outcomes now with it alone

[@serenahm]

I'm so glad it's working for you and helping you get your life back. I hope to try it myself someday when I can afford it. I have one question, though. Doesn't your psychiatrist work with you on what medications you can still take safely and which ones you need to stop? I would think she would be the best judge of that. Sounds like you need to go over that with her.

[@MsRayH]

I'd suggest talking to your doctor or pharmacist if you're on antidepressants or anti-anxiety meds. I'm working with my therapist and a doctor in the same office at the same time and I think it's the safest way to go. Best of luck and take care.

[@THBbon]

Been self medicating with this for 10 years. Works great. Easy to over do it though.

[@serenahm]

I would definitely not recommend using this to self-medicate. Not trying to be judgy here, just reminding you that you need a therapist to help you process all that comes up and integrate these experiences to get the real benefit of the treatment, plus a psychiatrist to monitor your treatment to make sure you're doing it safely. Self-medicating with anything is never a good idea.

[@nadianightlight3131]

How do you get it please? Struggling hard with life and feeling happiness

[@Biggerfoot]

I have had 9 unsuccessfully ssri trials i would hope my doctor would let me try this.

[@bojanglesobrien6883]

I’m currently doing ketamine infusions for PTSD and depression. It saved my life

[@bojanglesobrien6883]

@Nick Tollefson I’m good, thanks. All of my treatments are done under medical supervision with safeguards in place. No online hallucinogens for me.

[@davidtrotter4816]

Completed 6 infusions and sad to say it didn't work for me. I'm 5 days out from the last treatment.

[@Tiznado]

So what happens when the ketamine dose effect starts to wear off ? Is it withdrawals like regular anti depressant medication ?

[@bmbunch8825]

So my moms boyfriend has been in a severe depression for months if not years.... He is a veteran and has had a lot of trauma in his life. The main one being losing his wife in his early 30s to cancer. He's mostly been useless as a human since I've known him, but I feel for him. Its been years and began to depress my mom and now theyll both sleep until 2-3pm every weekend, hes daily. I get it having gone through depression. Im so excited the hospital and himself are willing to take this jump and its all through the VA! I hate the VA because I've watched his treatment for the last decade and they keep them on a cycle of drugs. This is the first time theyve offered him an alternative to their treatment and said theyd pay for him to go to the state school to get real treatment as long as hes approved.... I dont know what to say. I made them watch videos and evidence before. They ignored me. Now it's government approved and theyre all about it.

[@serenahm]

Please let us know how this turns out for him. I hope it works! With him and your mom in such a codependent relationship, maybe his improvement will help her. She needs her own therapy or support system like Al-Anon, though. But I hope the ketamine treatments will be a new start for the whole family.

[@jlstas1973]

@bmbunch8825 I didn't think the VA had approved ketamine therapy yet. I'm anxiously awaiting that day though!! I've been going to the same VA psychiatrist for my PTSD/MDD and have been on a never ending but frequently changing cycle of psych meds since 2012 and only just got offered and approved TMS therapy last Friday.

[@firstnameericlastnamecartm6306]

I'm going for a booster this week I'll post my thoughts and outcomes on it

[@emmawilson3103]

Bought mine in an online store where my stuff got delivered districtly...

[@emmawilson3103]

Tripsauthur

[@emmawilson3103]

On instagram***

[@firstnameericlastnamecartm6306]

@@emmawilson3103 that's not ketamine that's a dirty drug 😳 probably Fentanyl

[@firstnameericlastnamecartm6306]

Only get ketamine from a licensed company for trustworthy care

[@jeffmoestaygyi.1248]

Did mg first oral treatment yesterday, I’m not fixed by any means but I don’t want to die anymore.

[@frierson_40]

Great videos, I was able to overcome depression and anxiety which held me down for 3 years, all thanks to psychedelics, psilocybin mushroom, ketamine and LSD

[@chrissanti4856]

Same here, all thanks to LSD

[@Tristy_vii]

Where can I get it, really difficult to locate here

[@oparaprosper]

dr.fselman

[@elijahdick4405]

​​@@Tristy_viidid you find? I stumbled across Johnnycology store online 1 week ago, ordered and received my package today. You may want look up too

[@PhoenixFit2024]

I’m on my 4th of 6 treatments and sadly I don’t think this is working. I def didn’t have any immediate changes, but I have two more this week. However these are intense treatments…you get HIGH AF. But so far…nothing.

[@RyanKSDrac]

Hey I was really trying to listen and on some of my Bluetooth speakers the background music was drowning out what was being said, just in case that helps at all.

[@KoNqueeFtador]

Treatment in my town is 250 just for the infusion. But my medicaid covers the visit and the one on one therapy sessions. It did wonders for my depression. But i cant afford dosing a few times a month

[@aliciasternberg5778]

I'll refer you to this mate where I got mine from.

[@aliciasternberg5778]

Mycowillz.

[@aliciasternberg5778]

Hes on telegram.

[@ameerbasha9337]

Brother in which centre it is available ketamine infusion

[@tessbrand945]

Praying for a way to afford it. I’ve had 7 infusions. Money is becoming an issue at $450 a session. It helped me and was very noticeable in every aspect of my life. My major depression has robbed me of far too many years. My first treatment was 4/29 .

[@JB52520]

How it works for me: I can't get it. But if I could, it's too expensive. The depression has kept me out of work since 2001. Not that it matters, since I'd still be too lonely to want to live.

[@millicentegerton2532]

Bought mine from an online store and it’s affordable

[@millicentegerton2532]

On ig

[@millicentegerton2532]

Mycohenry 33

[@chgofirefighter]

You can't buy that stuff online, if you do, you're a fool to jeopardize your health and potentially your future. These online pharms are all scams! You have to research Ketamine clinics, some have sponsors that help offset the cost to even free.

[@fighterflight]

@@millicentegerton2532 taking it orally doesn’t get past the brain barrier sadly that’s why they do IV drips in clinical settings

[@PrettyMiyaw19159]

I have been on medications from every drug group, along with psychotherapy. They’re suggesting to switch from TCAs to SSRIs - which is moving two steps backwards. They’re not ruling out ECT, but I live in Australia, and Ketamine therapy is probably privatised. Haven’t heard anyone mention it and I haven’t come across people who’ve had it. I don’t think recovery is going to happen if they keep doing this to me.

[@kennedygary9031]

I'd appreciate your comment

[@kennedygary9031]

I bought some psychedelic product from a drugstore online they're very reliable ship discreet

[@kennedygary9031]

trippy_psyche01¿..

[@kennedygary9031]

ON INSTAGRAM

[@pocasanchez]

I mean, it's privatized everywhere that im aware of. If you want even mediocre medical care in the US, you pay. If you want quality medical care in the US, you pay way more. It costs thousands here and it's not covered, even when you're paying for insurance, just like every other effective treatment. Health insurance here is expensive and pretty much only partially covers ER, imaging, medication and some surgeries but nothing that actually improves one's health.

[@madarauchiha313]

Amazing !

[@Snowmobilesfolife123]

Ketamine was the best thing that ever happened to me for bi polar I feel like a normal person again I need a treatment every 3-4 months

[@ccreel64]

I can’t help but wonder if ketamine can help stroke patients recover mobility during rehab by re-wiring neural pathways. And stroke patients often have depression, sometimes from brain damage. Perhaps ketamine could help there too. I’d be interested in participating in a study on this.

[@lolak7438]

I'm nor covered for IV's or Spravato. My only option was the troches. I felt out of it and de- personal/realization. So finding GOOD treatments - whether it's Ketamine or therapy- are severely lacking. Seem to always be about money.

[@ry77801]

I seen those dots on the scan in my ketamine experience ❤ Amzing

[@michellejackson9699]

Are these studies based upon microdosing at home or in-clinic dosing?

[@Loreleifury]

I wonder if it would help with Myasthenia Gravis??

[@pacifiquebusiness]

Thank you 🙏

[@marlenebinder148]

i love ketamine but i feel like nothing was said because nothing was proven in this video. what are the doses? how is it administered? is it guided?

[@nadianightlight3131]

Can someone tell me if doctors or psychiatrists are actually willing to prescribe it or allow their patients to try it? They always seem so opposed to medications that actually work because of the people who abuse them

[@katietaptto4389]

I've been on anti anxiety and anti depressants for a couple of decades and will probably take them the rest of my life.... why can't I take something like this to actually help fix my brain

[@JasperRobins]

Dude is on Instagram as

[@JasperRobins]

Mycotinny

[@Jordanmiths]

I got mine too from mycotinny he got all kind of psychedelic stuffs and ships discreetly to any location his a life changer I highly recommend him

[@thecattoldmetodoit4329]

Does it work for generalised anxiety disorder?

[@christopherjohnson5748]

All of this sounds great, but how does the average person get access to not only ketamine but also the intensive CBT they refer to? My insurance doesn’t cover ketamine therapy and pays for one therapy session a week. So who are these Yale MDs working with? And when will this treatment inform standard treatment modalities beyond the research university?

[@frankleo9445]

I'll refer you to this doc online you can get it from he helped me..

[@frankleo9445]

He's on telegram as,

[@frankleo9445]

MyCodree

[@kayligo]

What are people paying in their area for Ketamine treatments? Does insurance ever cover it?

[@amimyster]

For 4 months I used it. 1/2 mg per day. Not only did it help my clinical depression, but helped my Fibromyalgia. Only reason I don't currently use it is because I'm worried about fentanyl and the fact that for no reason its still not used except by infusion. 28 g every 2 weeks. Why? When 1/2 mg everyday works!

[@tinataylor4203]

Look up Joyous the prescribe low dose at home ketamine treatments. The treatments ship after you pay an see the doctor. It cost me 600 for two small doses an four full dose sessions

[@ttrth424]

I’m curious to know if anyone who has tried IV infusions then switched to sublingual for boosters?…I start infusions in 18 days but at $850 /session, thinking of switching to oral for boosters if needed ($250/treatment)

[@tinataylor4203]

I’m getting it at home at 100 a treatment

[@EmilyLavelle-ScaryStoriesInc]

It has made me a more productive and consistent anxiety n depression free it’s amazing no side effects

[@joanncoopertroupe3506]

How do you look into it ? I live in lake city Fla, i most my life failed on many antidepressants.

[@marybenka8969]

I'll refer you to this mate where I got mine delivered discreetly***¿¿¿

[@marybenka8969]

On Instagram ¿

[@marybenka8969]

Tripwithrob5….

[@kennedygary9031]

I'd appreciate your comment

[@kennedygary9031]

I bought some psychedelic product from a drugstore online they're very reliable ship discreet

[@Celluarexpress]

This is the drug you want, it helps depression immensely and improves coding.

[@CarpeDiem601]

What about Psilocybin? Believe me I support anything that works but if there is a similar impact from a natural medicine I’d prefer that, right?

[@elijahdick4405]

Psilocybin does help too I must agree. I used to be a skeptic about them till I decided to give a try and ordered them from one - Johnnycology store online. Had my first psilocybin trip/treatment ever and must say it has helped increase my mood overall 😊

[@janepate]

Shrooms are a powerful psychedelic with a long history of recreational, medicinal, and spiritual use worldwide. Still, psychedelics can be unpredictable, and experts advise anyone interested in using them to start with a low dose and seek counseling from a medical professional. They are great impact in natural medicine.

[@ThePwillows]

I’m curious to know if they are saying that ketamine actually does all this based on our emotions afterwards or is it actually measurable amount of activity in certain a parts of our brain that we lost or haven’t used in forever due to ptsd, depression etc.. I take ketamine monthly and I fee differently but idk if it just because I’m high as a kite for a whole 24hrs.

[@frankleo9445]

It really works it changed my life I'll refer you to this doc online who got em..

[@frankleo9445]

He's on telegram as,

[@rlynn6658]

That is a really good point. How are they measuring this... it is not clear. I got a bit of a worried feeling when the woman at the end talked about how it's great to see the change on people's faces... because that could just be social conditioning too. There is the expectation that you'll feel better, so maybe you play it up to act positive, or maybe you believe that whole "smile and you'll feel better" thing, or just plain politeness, any number of other things. I spent some time in talk therapy and I didn't feel like I really made any progress, but my therapist waxed poetic about my general mood/demeanor at the end versus at the beginning when I first came to see her. I didn't have the heart to tell her I felt exactly the same. It was just that in the beginning, I decided to go with resting bitch face as my default. And when I got to know her I let it go. It didn't mean I actually was doing better, just that I decided to relax around her. I have to say that it felt really shitty to hear her say that. Because it felt like the only thing getting her out of bed in the morning was to see people get better, and my "getting better" was a boost to her ego and her career and sense of self-worth. So because I didn't actually get any better, I sort of failed her. And I couldn't be honest because it felt too rude. This is what happens when you are the fawn of the 4 F's - fight, flight, freeze, fawn. Thanks for coming to my TED Talk.

[@gr8dvd]

@@rlynn6658 If you’re 1/2 as insightful & smart as you’re funny, must ask… can guys have "resting bitch face"? If so, TOTALLY relatable… regardless, always trying to spare family & friends the truth of my the depths to which I’ve spiraled down… 20y which coincidentally or not is when I stopped high-level recreational sports - cycling 30-100 miles 1/week & full-court basketball.

[@chadholladay6228]

This is fantastic. Especially given the new published research findings related to standard anti-depressant SSRIs. I hope the CDC and FDA don't get involved, they'll screw it all up.

[@sarahharrison3405]

Hi Chad!!!!

[@7mike2300]

Wish this was the first option, antidepressants the side of effects wreck my body to the point where I they don't even have chance to get into my system.

[@HEROHCR2YT]

500th like 👍 lol. I have my 2nd infusion Monday, in 3 days.

[@ameerbasha9337]

Does it available in india please tell me brother I'm battling depression and ocd since 10 years

[@KiwikimNZ]

2? lol I have been on at least 15 different medications for my mental health including adhd. I have had 1 antidepressant work over the years which was Prozac, but that stopped working. Zoloft has kept the deep pit at bay, but I have been on everything including lithium Which was the worst. Maybe if I wasn’t diagnosed with bipolar when all the e time it was undiagnosed adhd then maybe things may have been different. I would love to try ketamine. A friend of mine who is a psychologist as treatment resistant depression and he has been micro dosing for about two years. The difference is incredible, I know he still has his moments but I can see such a difference, even the expression on his face. The irritability and anxiety has really decreased and his mood stable, better than going down right? We need to make treatments more available to people. I’ve struggled with this horrible illness for 30 plus years , of low mood anxiety and and have had two major depressive episodes both Itimes I had very bad suicidal Ideology with attempts. I can’t believe I am still here to be honest, my kids saved my life. They are my blessings c

[@Charlesjohn-oc8qu]

Psychedelic mushrooms completely helped me get out of addiction and depression. It totally rewired my mind Honestly, they worked better than antidepressants.

[@Charlesjohn-oc8qu]

Dude is on instagram

[@Charlesjohn-oc8qu]

@mrwrghttrip

[@timkenndy]

Mushrooms containing psilocybin saved my life. The aided my benzodiazepine withdrawal allowing me to quit illicit pill addiction after three years of heavy daily use before it would had became medically dangerous to quit. It has also helped me survive depression.

[@ellaaysun]

Psychedelics definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it's just so hard to source out here

[@lawsondave5076]

The Trips I've been having really helped me a lot,I finally feel in control of my emotions and my future and things that used to be mundane to me now seem incredible and full of nuance on top of that I'm way less driven by my ego and I have alot more empathy as well

[@johnjude2402]

@@ellaaysun I was having this constant, unbearable anxiety due to work stress. Not until I came across *dr_noels* a very intelligent mycologist. He saved my life honestly

[@amelieggarnnet7982]

​@@ellaaysunHey I’ll refer you to this specialist who guided me through My psychedelics experience he’s got all kinda psychedelics and ships discreetly to any location ^^

[@amelieggarnnet7982]

Arabicastorez 👈

[@alexandrusebastian7495]

Can't wait to try it. I need to fix my life.

[@williampool812]

I'd appreciate your comment

[@williampool812]

I bought some psychedelic product from a drugstore online they're very reliable ship discreet

[@williampool812]

trippy_psyche1¿..

[@williampool812]

ON INSTAGRAM

[@rosewood8503]

@@williampool812 hey 👋 I'm interested in some DMT and special k is there any way he ship to the UK?

[@ArielyGarcia]

It’s really messed up that people need to try two different ssri’s in order to be eligible for this treatment. I’ve had depression for over ten years and I’m so desespérate to not live like this anymore.

[@jessicapalmer293]

I recently started microdosing and using psilocybin coupled with therapy. It has helped opened my emotions up as its something I've had trouble with, it also helped me with my depression and anxiety issues. I get supplies from a recommended source

[@jessicapalmer293]

On the in⭐️⭐️gram.

[@jessicapalmer293]

Mega_spore

[@TorEtCetera]

Yes totally messed up. Modern medicine has got it all backwards Just so you know, there are many ways to access ketamine. Keep going ♥️

[@theresaoconnor5115]

I suffer from severe OCD & DEPRESSION WITH TERRIBLE ANXIETY!!! WHERE CAN I GET HELP THAT MEDICAID WILL COVER THIS??? I’VE suffered since I’ve been 9 years old and im 60 and ALL THE ANTI-DEPRESSANTS AND ANTI-ANXIETY MEDS ALONG WITH TONS OF OCD MEDS THAT ALL DO NOT HELP WHATSOEVER!! I NEED HELP AND RELIEF SO THAT I CAN FEEL “NORMAL” AND HAVE PEACE OF MIND, LITERALLY,

[@lilianparle4822]

The best solution is natural organic supplements, I was on anti depressant drugs for 18years and a friend introduced me to those supplements and I decided to check the out and definitely changed my life. Is really a testimony.

[@lilianparle4822]

I will help you, reach out to charlesmyco_ Explain everything to him he will give you what is required for Your problems.

[@lilianparle4822]

He's on instagram.

[@tloo5649]

Does it help with anxiety, OCD, ADHD or other mental illness or personality disorder?

[@smithz749]

Yes, it does, HIT UP MACROPAUL6

[@smithz749]

On Instagram

[@smithz749]

He the best online drugstore I know, he got DMT, LSD, and more for depression

[@janepate]

I would rather advise you to take lion's mane or chaga mushroom.

[@janepate]

Or check on charlesmyco_

[@aprilrule8132]

How your traumas were being reset but did they come up and you successfully gave them first to get healed. We can’t mask the healing we have to address it and that mean feel it and face it to get it out. And does this medication take away your sense of emotion or make you zombie like or are you better because you don’t feel anything to react to. I see you eating works but what is the person going through for it to work. . Like is it a bandsaw are you able to mourn your frown by suppressing the sad feelings along with it? I need more info on what it’s actually doing to help not what it helped.

[@AlbertJoe-jf6bl]

Yo i could recommend you to a specialist who guide me through my experience he got all kinds of psychedelics product like dmt, lsd, mushrooms, chocolate bars, edibles, polkadot, psilocybin and alot more, he could also guide you through if you're a newbie

[@AlbertJoe-jf6bl]

@novatripps

[@AlbertJoe-jf6bl]

Dude is on Instagram

[@lucesca]

My mom wants me to try this but I'm scared cause it seems to be pretty new. It doesn't sound like anyone knows if there are long-term affects, and I'm a teenager so my brain isn't even finished developing.

[@koyaaanisquatsi]

do you struggle with depression? I'd say wait it out till you are a bit older (unless you have suicidal ideation)

[@Paisleyrosa]

I’d run for the hills. Like you said, your brain is still developing. My parents put me on anti depressants at 15 for what was normal teenage angst, and my brain has not been able to function without them ever since. I’m 45. Not to mention they don’t work anyway.

[@kostas43]

What happened if you stop spravsto????

[@thomasleifseth5201]

i no longer think ONLY about suicide and how to do it ! Than God I got that treatment :-)

[@thomasleifseth5201]

@Glowi Main Some of the antidepressiva has a warning that suicide is the Side effect ;LOL! cause you get so flat you dont care. my mother is a negative person, on common anti depressiva. Sitting like a Person who waits yo die while wathing tv. i hope these Micro dosing comes soon. Cause old people cant have this Tripping effect, it scare them away. Thank you that video wa great, that beatuful girl , I see a girl like that i think she ot depressed. But life today is social isoltaion, in a box/apartment . But is Good Now News travel so fast ;-)

[@carinaaulis4118]

At least two trials?!? Why am I on at least 15th trial of medication for anxiety and depression all of which none actually make a difference? It's so f*cking frustrating that the answers are out there and most of us just can seems to get access to them.

[@TancheapMcFatass]

I have permanent brain damage from ketamine that for some reason I only experience symptoms when I do it. Absused it non-stop for about 6-7 months and some fuses up in my head blew now nothing makes sense when I do ketamine literally nothing my brain starts sending signals down the wrong pathways I even started convulsing last time I used it. God I miss ketamine

[@rocker8692]

Do you still take your ssri meds when you do it?

[@popadict24]

They require you to take a anti depressant when you take spravato

[@ivux_468.]

Charlesmyco_ got some psychedelic products, I suggest you hit him up

[@ivux_468.]

Charlesmyco_

[@ivux_468.]

On instagram

[@Christinesobsevations]

I live near yale . I have Medicaid . From what I have heard it’s not covered

[@courtlandperreault9123]

psilocybin containing mushrooms saved my life. The drastically reduced my benzodiazepine withdrawal allowing me to quite illicit pill addiction after three years of heavy daily use before it would had became medically dangerous to quit. it has also helped me survive depression.

[@clarajoe8485]

Psychedelics definitely have potential to deal with mental health symptoms like anxiety and depression, i would like to try them again but it's just so hard to source out here

[@joecopper2241]

I was having this constant unbearable anixety due to work stress, not until i came across dr.healingstrain a very intelligent mycologist. He saved my life honestly

[@joecopper2241]

I G

[@Carson272]

i feel the same way too. i put too much on my plate and it definitely affects my stress and anxiety levels. I am also glad to be a part of this community

[@gannetsigismond3075]

@@joecopper2241 thanks mate, i'll get in touch with him right away

[@citizenpcorp1111]

Any word on it helping schizophrenia and also tinnitus. ?

[@Laureens.1]

There are positive testimonies and I have tried them. You should give it a trial

[@Laureens.1]

drgavin_trips That’s the mycologist game name

[@Laureens.1]

On instagra♍️

[@shokotatsuno-p5497]

Shrooms are the safest recreational drug to take, it should be made available every where.

[@HarshalSureshGhanekar-sw6vv]

What are the side effects of ketamine

[@TheManWhoCan1998]

I’ve received many high dose (100mg IM) injections. Really the only major side effect is that it’s hard to do vigorous activity after treatment on the same day. So take it easy and slow. It can be very tiring as well. But it also makes things look crisp and clear. And the best part of it all is the incredible antidepressant effects

[@NoirL.A.]

I DID PSYCHADELIC THERAPY SOME YEARS AGO IT WAS INCREDIBLY REWARDING BUT MY THERAPIST MOVED OUT OF STATE SO I HAVE TO SEEK OTHER OPTIONS. I LOOKED INTO KETAMINE BUT I'VE READ IT'S NOT FULLY LEGAL YET AND IT'S INSANELY EXPENSIVE. NOT SURE HOW TO PROCEED FROM HERE

[@jameskim3915]

I can recommend you to where I get my stuff from an online store.

[@jameskim3915]

He's on Instagrams also on Telegram with the below handle as...

[@jameskim3915]

Mycopete..

[@NoirL.A.]

@@jameskim3915 cool thanx

[@kaceyross8955]

If it's legal in Arkansas...

[@daffydrunkv1659]

When is depressing this bad to think about taking ketamine I’ve thought about killing my self and hurt myself in the past and haven’t had a good antidepressant I’ve switched 3

[@searchingforequanimity2017]

Hope you're okay. Please reach out if you need to talk... there is hope

[@mraereed]

I have a TBI MDD and PTSD. I have been approved for the Es-ketamine "Spravato nasal spray" I am so hopeful.

[@mraereed]

@James Becketts I've used DMT and mushrooms and LSD to regain neuron pathways after my brain injury. It really helped to recover memory. It's just expensive to use in the way I will get the Spravato. Twice a week for the first 2 weeks, then once a week, with monthly doses available as upkeep.

[@user-nz9tb6gi3w]

I know this is an old thread, but wondering if you had the treatment and if it helped. I'm in the same situation.

[@mraereed]

@@user-nz9tb6gi3w Yes! I'm so glad you reached out! I just came from my Spravato appointment. I'm having the treatment once a month now. It has been life changing. I was also put on a new antidepressant and I'm receiving one on one counseling.

[@mraereed]

@@user-nz9tb6gi3w A great deal of memory loss. I had seizures for 2 years following my brain injury. That was 2009. I just feel so disconnected from that time of my life.

[@user-nz9tb6gi3w]

@@mraereed - that's good to hear. What kind of TBI symptoms were you dealing with (if you don't mind me asking)? I had a bad car wreck in August 2022 and feel so disconnected from normalcy. thanks!!

[@Arcticstar69]

I use ketamine against my depressive tendency. It is magically great for this purpose.