This explanation of CF is so comprehensive, thanks, really helps for my patho class.
@sciencenerd76392 жыл бұрын
I learned a lot. Thanks so much Khan Academy!
@pedrooliveiramonteiro7 жыл бұрын
HALLELLUJAH! A simple explanation of how chloride, despite being low in every other exocrine secretion, is high in sweat!!! Thank you !!
@jasminerogers5756 Жыл бұрын
Wow you really broke this down!!!
@isbllavttria10 жыл бұрын
Clear and Simple! Thank you!
@CFlifestyleFoundation2 жыл бұрын
Thank you for sharing this information.
@helenaalvarez62119 жыл бұрын
I finally understand this now, thanks to you! Cheers xx
@nikegrl8910 жыл бұрын
Thank you for this explanation!
@Orangesoda657 жыл бұрын
Spent too much time talking about the skin effects and not enough time talking about the pulmonary effects, which are more pathologic.
@KimmieTheGreat364 жыл бұрын
There are many other videos of her going into detail on respiratory complications of cystic fibrosis...so watch them.
@stephenprice33574 жыл бұрын
orangesoda that was exactly what i was thinking
@qp53374 жыл бұрын
She is talking about the sweat gland because of the way CF is diagnosed
@ハネスカツミ2 жыл бұрын
@@qp5337 thank you april
@alimajed884310 жыл бұрын
Great, very simple and clear :)
@RamYadav-el7gv4 жыл бұрын
simply awesome explanation
@lindush944 жыл бұрын
Thank you ❤
@CHEPINO1178 жыл бұрын
Simple y practico. Love it!!
@professorneal3574 жыл бұрын
Loved the explanation
@samuelchinonso26092 жыл бұрын
You are too good
@mareehugo54139 жыл бұрын
Brilliant explanation!
@havvanurozekici7 жыл бұрын
I've watched this video in order to learn about CFTR but what happened? Then I learned that in sweat glands CFTR mediated the movement of Cl from outside of the cell to inside; but in lungs, CFTR makes Cl- ions to go to the outside from inside. I don't know. I'm confused. My sources: Wikipedia and Pubmed.
@havvanurozekici7 жыл бұрын
You also explained lung for some seconds but it was understood as they are the same, at least for me.
@yogayantra5 жыл бұрын
thank you. So is cystic fibrosis pathology = mucoviscidosis???? Thanks for your reply. [NB: i am a student]
@bherulallohar44833 жыл бұрын
😍
@mariam31149 жыл бұрын
Thanx⛄
@elijahsmith56836 ай бұрын
So the difference between the sweat glands and everywhere else is you have decreased Cl- reabsorption in the sweat glands causing salty taste, and increased reabsorption of Na+ in the respiratory, GI, reproductive causing thick secretions.
@albrestevez7 жыл бұрын
I don't get it. You say In normal CFTR your get NaCl- outside because their channels work fine. In mutated CFTR if Cl- cant get out of the sweat gland and Na+ neither because Cl- channel is closed and Na+ follows Cl-, then how are you gonna get more amount of NaCl- outside???
@muhammedceliktas29177 жыл бұрын
If the channels work you absorb some of Na and Cl that much you need but if the channels don't work I mean CFTR with channels you won't be able to absorb Na and Cl and you'll throw them both out the body by sweating
@muhammedceliktas29177 жыл бұрын
And also CFTR is for Cl.i forgot to say that in the previous comment.i hope you got it now
@lindush944 жыл бұрын
No she said that. In normal CFTR NaCl gets absorbed and only a small amount gets outside in the surface of the skin... but in non-normal CFTR - NaCl doesnt get absorbed (because the cl chanels dont work) thats why more amount of NaCl gets outside on the surface of the skin..
@mateen_sindi Жыл бұрын
I still don't get it
@AhmedMD8 жыл бұрын
So beautiful! thanks a lot.BTW what is the name of the app you are using for painting and typing in this video?
@kjonesusmc7 жыл бұрын
I wish I had your handwriting... I wish Sal Khan had your handwriting haha.
@timothyhsu94188 жыл бұрын
sweet heart
@roseb73996 жыл бұрын
This isn't very useful by itself- salty sweat isn't the major issue with CF.....
@iwo6122 жыл бұрын
It’s the CFTR, not CFTCR.
@STF1991099 жыл бұрын
How did the chloride get in the sweat gland at the first place ?
@abdulaziz.94717 жыл бұрын
Sweat is a blood filtrate.
@hoalethi34423 жыл бұрын
the sound is not good I am quite disappointed
@rayyanabuoliem30469 жыл бұрын
your sound very smart that I got turned on watching a Pathophysiology video What a time to be alive thank you Evolution for making smart girls!!
@rayyanabuoliem30469 жыл бұрын
you**
@vincent10kd5 жыл бұрын
lmao
@eviedson4 жыл бұрын
Lol, this video kinda sucked there's so much more to it. I'll stick to my textbook!
@geromepaule53289 жыл бұрын
the writing is very disturbing (i mean the sound) arrggg