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Food Scientist and Registered Nutritionist, Kriben Govender (Honours Degree in Food Science & Technology) has an insightful conversation with Chief Scientific Officer of Microbiome Labs, Kiran Krishnan on How to build a resilient microbiome, metabolic endotoxemia (leaky gut), the negative impact of lipopolysaccharides (LPS), the diabetes pandemic, probiotics for optimal health, spore-based probiotics, postbiotics, butyrate and acne control, keystone bacteria in the gut and much more
Bio:
Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He is currently involved in 9 novel human clinical trials on probiotics and the human microbiome. Kiran is also on the Scientific Advisory Board for 5 other companies in the industry. Kiran offers his extensive knowledge and practical application of the latest science on human microbiome as it relates to health and wellness.
Topics discussed:
* Start 00:00
* Kiran's origin story 02:05
* What does good gut health look like? 08:55
* The concept of "resilience" in gut health 09:25
* What about different dietary regimes like paleo, vegan, carnivore etc? 09:45
* Human evolution of omnivores 09:55
* Gut sensitivity in the modern world 11:33
* How to foster resilience 14:08
* The concept of "Holobiome" 14:15
* Living in an antibiotic laden world 15:13
* Exposure from personal care products 16:44
* Maximising exposure to environmental microbes 17:07
* Allergies, Asthma and the microbiome 17:18
* Diversity of diet like our ancestors 20:14
* Spore based bacteria 21:10
* Metabolic endotoxemia (leaky gut) and chronic disease 21:45
* Lipopolysaccharides, Gram-Positive and Gram-Negative Bacteria 24:12
* Sepsis and bacteraemia signalling 26:55
* LPS and Chronic inflammation, Rheumatoid Arthritis, Anxiety and Depression, Alzheimer's 28:30
* LPS toxicity and bacterial types 30:15
* LPS and Diabetes Risk 31:02
* LPS mechanism on impairing blood sugar modulation 33:22
* The impact of C-section on gut microbiome composition 35:50
* Antibiotics and the microbiome 37:10
* What is a probiotic organism? 40:28
* Where do probiotics come from? 41:45
* The origin of Spore based probiotics 44:05
* What is a spore-based bacteria? 45:02
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* The gastric barrier, bile salts and pancreatic enzymes 47:03
* Short Chain Fatty Acids, Postbiotics and Metformin 49:25
* Butyrate and insulin sensitivity 51:20
* Butyrate and acne control 52:20
* Oligosaccharide based prebiotics- FOS, GOS, XYLO 52:57
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* Keystone Species in the Microbiome: Akkermansia, Faecalibacterium, Bifidobacteria, Ruminocococus 55:01
* The benefits of bacteria (biological response modifiers), BLP1, Micro RNA, Microvesicles 57:10
* Intra- kingdom communication and gene expression 1:00:10
* The importance of subspecies classification and associated health benefits 1:00:38
* The science of postbiotics and AMUC 1:02:50
* Megasporebiotic and Leaky Gut 1:04:20
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Brought to you by:
Nourishme Organics- The Gut Health Superstore
Check out our range of clinically proven probiotic supplements including Microbiome Labs Megasporebiotic:
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Connect with Kiran Krishnan
Website- microbiomelabs.com/
Connect with Kriben Govender:
Facebook- / kribengee
Instagram- / kribengovender
KZbin- kzbin.info...
Gut Health Gurus Facebook Group: / nourishmeorganics
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