Lecture 11, concept 17: Protein structure RMSD vs. sequence identity

[@blackmamaessa]

so much squeaking haha. Thank you for the good video!!! Doing structural bioinformatics exam soon

[@quinxx12]

Hey Erik! Are there other measures for structure similarity which also take local "groupings" into consideration? I would like to find a measure which quantifies the impact of replacing a certain AA has on the protein structure. So I was thinking that this number would reflect whether just some slight displacement or drastic confirmational changes happen.

[@soniagesmundo4209]

Thank you so much! I finally understood this! Super helpuful! Keep up the good work

[@Clark_Kent_ZA]

Thank you Erik. Where can I get the graphs you used?

[@jean-eliseeyao7290]

Thank you so much for this clear explanation By any chance do you have an implementation of it?

[@miyssaimam3228]

I appreciate the passion you are teaching with 💜