Lipid Management: The Ins and Outs of Inclisiran

Christopher V. DeSimone, MD, PhD, and Stephen L. Kopecky, MD, discuss lipid management and the use of inclisiran, an siRNA drug that inhibits the RNA from making PCSK9. www.medscape.com/viewarticle/...

[@kosmosbjm]

I’d like to hear from those who have had the infusion therapy every three months and what are the side effects?

[@sereanaduwai8313]

The question that needs to be asked is how many patients have who taken this injectable pcsk9i reduced their cholesterol and have also reduced their risk of heart attacks?

[@zakirzak1494]

Thank you....Inclisiran , a PSK9 inhibitor is an adjunct to Statins, would it improve Lipoprotein A??

[@newheavyion]

only by -20%, its a side effect, but a good one ;)

[@garywitcomb4750]

None here had it two weeks ago

[@thibaudjacquemaire7076]

For me -20% too.

[@ChloeBensonBeautyBoxes]

I’m getting my first shot today

[@felixcat9455]

How did it go? Any side effects?

[@stars-are-us]

I got my injection. No adverse reaction.

[@felixcat9455]

I wonder if the patients that stop their self injection pcsk9i are doing so because of side effects or they get tired of the injections. Would love to get patient perspectives rather than just those of medical personnel.

[@kosmosbjm]

My doctor mentioned that many of his patients just didn’t like injecting themselves, so they eventually opted for the infusion shots. I’m just concerned about the side effects.

[@thibaudjacquemaire7076]

Probably some due to the cost. No side effect from Praluent to me; actually, a walk in the park compared to statins!

[@DonnyDump]

Sounds like a paid advertisement. 4:21

[@lesjackson362]

Their own research indicates no difference in cv events.