Lung-specific Angiogenesis Study by Fibrin Gel Implantation | Protocol Preview

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Implantation of Fibrin Gel on Mouse Lung to Study Lung-specific Angiogenesis - a 2 minute Preview of the Experimental Protocol
Tadanori Mammoto, Akiko Mammoto
Boston Children's Hospital and Harvard Medical School, Vascular Biology Program, Department of Surgery;
Recapitulation of the organ-specific microenvironment, which stimulates local angiogenesis, is indispensable for successful regeneration of damaged tissues. This report demonstrates a novel method to implant fibrin gels on the lung surface of living mouse in order to explore how the lung-specific microenvironment modulates angiogenesis and alveolar regeneration in adult mouse.
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