Melatonin KILLS Cancer: ENHANCES Metabolic Therapy & Chemoradiation

[@DrCaseyPeavler]

Can you believe how powerful melatonin can be in the fight against cancer?

[@devaapurna608]

Great caption "A full-service, anti-cancer agent". Very intriguing headline!👍👏👌

[@Fvission]

I have stage 4 brain cancer (GBM and Gliosarcoma) currently 39, doing carnivore diet and extremely fit! Trying to take DON from Thomas Seyfried, Daniel Orrego and Dr. Duraj. Currently taking Ivermectin and Fendendazole and waiting on mebendazole. I've been taking daily melatonin every day at just 5mg, so that sounds pretty extreme and awesome to go way up! Thanks for that info. I will check out more of your videos

[@DrCaseyPeavler]

Man I am sorry you are in the position you are in. Very courageous of you to go the route you are. Where do you live? Do you have access to good sun year round?

[@officespaceredstapler2287]

So sorry to hear of your situation. FWIW...........my wife, stage 4 met breast to bones/liver/lungs/brain/lymph. Conventional chemo moderately effective. Combined fasting (fast mimicking diet) with 500mg melatonin daily (divided doses through the day) with attention to gut health/organic plant based diet with chemo/checkpoint inhibitor. Five month later no cancer present anywhere per CT/PET /Signatera genetic test. Additionally she had very little in the way of side effect from the conventional drugs that are very hard on most people. Melatonin has likely played a big part in her results. Best of luck.

[@MargaretTruststheLord]

Which latitude do you live at? Country? Makes a huge difference!

[@lindaanderson1921]

So sorry to hear this !! May I ask, did you take the C19 Vcine

[@lacharmer441]

Look up Dr. Jack Kruse, he talks about our history of getting away from natural lighting and a big increase in cancer since LED lights came about.

[@donaglosser4272]

Thanks for all this information. I’ll do anything to stay away from any chemo or radiation

[@DrCaseyPeavler]

You are very welcome! Hope this information helps you!

[@DrCaseyPeavler]

There are ALOT of additional things you could be doing. I will try to go over as many modalities on this channel as I can that has evidence behind it. You guys need clinical guidance. Please please please find a local integrative doctor who has a clue, and work together as a team.

[@KRose-jz7fj]

Thanks for info, fighting the ovar cancer so love all your info. Years ago I read somewhere not to supplement melatonin because it’s a hormone, it ll mess with your hormones. So I appreciate real info.

[@DrCaseyPeavler]

Yes it seems to be a worthy addition to just about anyone’s treatment strategy. God bless your fight!

[@DCLearningtoLive]

Melatonin is a brilliant hormone, indeed as are they all for so many reasons, but this shows how important our sleep cycles are. great information, thank you

[@DrCaseyPeavler]

Thanks David! Melatonin is amazing truly

[@michaelayalaathotmai]

Please remember that it is darkness, not sleep, that promotes melatonin production. I suspect it's major benefit among the many is it's role as a signaling molecule coordinating and synchronizing the circadian rhythms of the organs and cells of the body.

[@michaelayalaathotmai]

​@@DrCaseyPeavlerThank you for this great series on melatonin.

[@DrCaseyPeavler]

Thank you for your support! The finale is coming Monday, stay tuned…

[@2makeshiftwings]

Astonishing! I just so appreciate your content. Thank you so much 🙏

[@DrCaseyPeavler]

You are very welcome! Please share with family and friends who need this information!

[@jasonjohnson5408]

Another great video, I've just shared your channel to a prominent group I'm extensively involved in.

[@DrCaseyPeavler]

Thank you very much! I hope this information is helpful to you or those in the group!

[@OldNeoMatrix]

Please create an easy to share "Melatonin" play list. 👍

[@DrCaseyPeavler]

Mitochondria or melatonin playlist?

[@sr.9402]

Melatonin would be great - i would appreciate it.

[@AntonioGonzalezESP]

Brilliant video!! Blown away as alway, thank you & thanks melatonin

[@DrCaseyPeavler]

I am glad you liked it!

[@CynthiaFranco-tx3yw]

I stumbled upon this and I’m amazed . I have need diagnosed with triple stage 3 negative Breast cancer . Have undergone chemo treatments 7..side affects were terrible !! I was unable to use my right leg ..went Er they couldn’t find reason !! I’m convinced chemo isn’t for me I take many supplements but melatonin very low dosage ! Thinking I can increase to 30 see what it does .. I appreciate any infor and please continue your videos it will save lives god willing mine too!!

[@DrCaseyPeavler]

I am sorry about your diagnosis and the horrible side effects of the treatment. That doesn't seem like "first, do no harm" to me. I would find a like minded local integrative doctor to guide you on the dosages of these things, in particular melatonin. I am glad you like the info! I am just getting started! God bless your journey back to health!

[@devaapurna608]

As per integrative oncologist, who recommended huge mgs of all the anti-cancer supplements for this 5' 87 lb female - he said 50 mg melatonin before bed, so starting low and slow as always (learned the hard way years ago) I took 5 mgs before bed and staggered everywhere I went the following day. May try halving with pill cutter because I want anti-cancer effects.🙏🤞

[@DrCaseyPeavler]

I’ve heard people are getting bulk powder and taking like teaspoon. If pills are an issue…

[@lisamaree6259]

Op of comment is talking about the strong sedative affect with problematic drowsiness the next day even at low level. I also wonder how do we get to these higher levels when 5mg can have a strong sedative effect. I alsw​@@DrCaseyPeavler

[@DrCaseyPeavler]

I suspect like with most things there is a risk vs benefit. If you don’t have cancer, probably don’t even mess with supplements. If you have cancer, then that is a different story.

[@debiwillis9045]

​@DrCaseyPeavler and aren't the doses spread out during the day? And not at night

[@pimjanvimuktanonda8915]

Dr. Casey this is a great information. Do you have further information on the level of melatonin that is effective for prevention of cancer recurrence?

[@DrCaseyPeavler]

I don’t give dosages or medical advice. I would say this. If you have not maximized your endogenous production yet, start there.

[@filomenamillermiller3035]

Grateful for all this information ! It's a lot to process but I know it will make a difference.

[@DrCaseyPeavler]

I am happy to be of assistance! Yes it is a lot, the series builds on its knowledge each video. Yes I also believe this information can be life changing.

[@marshallsaltzman9924]

Amazing work 🥇

[@DrCaseyPeavler]

Thank you! Glad you enjoyed it!

[@r.davidyoung7242]

Thanks!

[@r.davidyoung7242]

Do you think melatonin will help those fighting multiple myeloma? 🎉 Thank you for your awesome YTC.

[@DrCaseyPeavler]

You are very welcome! Thank you for your support!

[@r.davidyoung7242]

Do u think melatonin will help those fighting multiple myeloma ca?

[@DrCaseyPeavler]

Yes I do. If you trust the research of Dr. Thomas Seyfried, then all cancer cells require glucose and glutamine to survive. Melatonin shuts the glucose side of the equation down to a degree. It is a powerful tool!

[@raykinney9907]

Melatonin can distinguish between healthy and unhealthy cells, and THEN also treat those different cells differently? Wow.

[@DrCaseyPeavler]

It’s incredible Ray.

[@fatimabonte-go3vy]

Hy doctor how many mg is best to take?

[@DrCaseyPeavler]

I hope you know by now I am going to encourage sunlight during the day and darkness at night as first, second, and third intervention. If you have a serious disease, then the discussion can place about adding it as a supplement to max sun exposure and minimum light at night.

[@raykinney9907]

@@DrCaseyPeavler I get it!, If you are not already deep into a cancer issue to consider adding massive doses, getting daily 'hits' multiple times a day, of NIR via just going outside frequently (for free), is the 'fix' and free preventive thing that can be mitochondrial melatonin, AND D3 complexity of hormone preventive complexity! Early morning first light, get out there for that fist 'dose'.

[@DrCaseyPeavler]

Well said Ray. Thank you

[@raykinney9907]

AND, PREVENTION too!

[@DrCaseyPeavler]

An ounce of prevention is worth more than a pound of cure..

[@lisamaree6259]

Does red and near red light therapy naturally increase your bodies melatonin levels and is it significant?

[@DrCaseyPeavler]

Yes! Probably 3-4x more than circadian rhythm spike at night after about 20min of exposure.

[@tadmarshall2739]

Has a picture emerged about dosing of supplemental melatonin, quantity and timing? I assume that if I don't have cancer yet (that I know of) then mega-dosing is not indicated, but for cancer prevention do we know how much to take? Great content, I am learning so much from you, thanks!

[@DrCaseyPeavler]

Not that I have seen. But considering you can make nearly unlimited quantities by exposing yourself to the sun, it does seem more is better. I’ve seen integrative doctors recommend anything from 30mg to 480mg daily and there are people in this very community taking upwards of 4grams per day. For prevention stick to the sun and improving your circadian release, imho

[@lucybecker8]

Dr Russell Reiter, melatonin researcher and expert recommends 65 mg night and 40mg during day, at 12 pm and 4 pm for cancer of the breast. He is credentialed check it, loads of publications on PubMed. Ernesto Edinger MD three times over, worked with melatonin and Russian astronauts - 300 mg per day, I think, just verify for yourself. Dietrich Klinghardt MD use 1,000- 6,000 mg for various illnesses. Uses suppositories and patches for higher absorbu87htion. Oral delivery goes through liver, only 10% of oral dose gets into body. Doris Loh also published on melaton8n, she says she takes 3000 mg daily in divided doses.

[@raykinney9907]

@@DrCaseyPeavler And logical careful daylight exposure, especially in early morning (dawn) light, is ALSO FREE!

[@raykinney9907]

Manufacture of supplements seem to interject more potential issues like unintended contamination, not thought enough about by producers (e.g possibly deuterium content)? IMHO, getting melatonin via early morning daylight exposure, that also sets up better circadian hormonal functioning in the body, likely has less potential for (lack of adequate thought and research). And, we have been evolutionarily adapted to thousands of years (to say the least) of thriving with such daylight. So, likely we did not suffer from a 'deficiency of light supplementation'! For due diligence prevention, I'd say that early morning light NIR and subsequent frequent short exposures to daylight during the day, to stay 'topped off' for NIR (not to mention the amazing D3 hormone series of analogues) would be better than issues with manufactured melatonin. All of this is considering prevention, not if given more pathologic conditions that might necessitate needing higher dose utility.

[@DrCaseyPeavler]

Context is king. For people without cancer, I personally, despite my reverence for the substance, would not recommend supplementing. If you have cancer, I think is likely a must but the dosing, timing and scheduling recommended by various people is all over the place.

[@Roberto-cg2gr]

How to increase melatonin?

[@DrCaseyPeavler]

I have a couple videos about this. Videos 1 and 2 on melatonin. Two ends of the answer. How to maximize nocturnal circadian melatonin release, and how to maximize intra-cellular melatonin.

[@lschwaier]

Supplement or get 8 hours of sleep with eye mask. Is my honest guesses lol

[@raykinney9907]

Welcome to complex systems! I wonder what percentage of oncologists have read these papers, included any of this information into protocols, and realized that frequent NIR quantum exposures to daylight are evolutionarily adapted and conserved on-going mechanisms of action of light. FREE light?!? And, in absence of these exposure frequencies, degradation of beneficial mechanisms are more than likely? Biologically, AND socially, this is mind boggling! Questions abound.

[@DrCaseyPeavler]

I would guess very few because it’s not like these cancer patients coming into the hospitals who have very prominent oncology teams come in on high dose melatonin….sad

[@raykinney9907]

Friends diagnosed with cancer, diagnosed with PD, AD, ED, etc. etc. etc. seem even more fearful of being out in daylight, reach for sunblock, wear sunglasses, and all light their nights with LED. It now seems like I should not have to try to suggest to them that they might really be better off medically, if they had habits of frequent logical daylight exposure rather than hiding from it. But, under medical system care, shouldn't some 'evidence-based' practitioners be at least more curious about the research existing already, such as these papers? And, what about prevention advice not ever taking such research into account? If I suggest such knowledge should probably be readily available, and if I say that while outside in the morning sun, w/o sunscreen, sunglasses, and a hat on, they look at me as if I were an environmental terrorist.

[@ronalddesilva8730]

The medical system is not interested in a cure. Only long term treatments that they can cash in on. Threaten the system and risk loosing your Dr license. So, tow the line and only use and suggest treatments that are AMA approved to keep the cash flowing into the system. It’s all about the money unfortunately.

[@raykinney9907]

@@DrCaseyPeavler And, not getting NIR regularly either.

[@DrCaseyPeavler]

I think a lot of mainstream folks just keep their head down, finish their shift and unplug. They are taught it’s all genetic, that the body is fundamentally broken. We need a whole new system and paradigm. Sadly.

[@zigzag8162]

Started topical melatonin on my face and facial hair to see what happens

[@DrCaseyPeavler]

Keep me posted on your progress? What are your goals with using it?

[@zigzag8162]

​@@DrCaseyPeavler Sure thing. My skin is a little bumpy around my mouth, and my mustache is turning blonde from black. Going to see if it improves the skin texture and darkens my facial hair back to its original color. I'm just using liquid melatonin in a vial, nothing specially formulated.

[@DrCaseyPeavler]

Interesting. I will have to tell you, you make melatonin in every skin cell when you get your face out in the sun lol. But let me know how it goes with your experiment.

[@JonathanVigier-s9f]

Hello doctor thank for your vidéo. 1200 mg of melatonin can be enough ? For someone who take a lots ot think like metabloc scot inhibitor berberine etc… who maintain low gki and do a lot of fasting. And someone that doesnt do standard of care… thanks you

[@DrCaseyPeavler]

It sounds like you are doing a lot! I can’t provide medical advice such as dosages on here I am sorry!

[@scottmaas1959]

At what dosage and instructions on how often to take it. My PSA in now less than 0.1 after radiation what is the proper maintenance dosage plan.

[@DrCaseyPeavler]

Thank you for reaching out and I am glad your PSA is less than 0.1 after your treatment. The dosing, timing and scheduling needs to between you and your integrative doctor. That being said, I have seen doses from 30-180mg at night to upwards of 120mg 4x/d recommended by some integrative oncologists. I have seen people in this community who are taking 1000-4000mg of melatonin per day. What I would recommend without reservation is making the maximum amount of endogenous intracellular melatonin by maximizing your sunlight/infrared exposure. Perfecting your circadian rhythm, removing all light at night and maximizing your nocturnal pineal release of melatonin before you take any supplements.

[@Hansen23900]

Why do some get headaches and dry eyes from a very low dose of melatonin ??

[@DrCaseyPeavler]

I am not sure why that would be. Have you tried several brands? I’m sure you are aware at this point, for most cases, I recommend you make your own melatonin through UV/IR exposure and darkness at night..

[@miabwillson]

It’s the additives in the product. Make sure you get the cleanest melatonin possible. Pure Encapsulations has 20mg clean tablets. I take 3 a night no problem.

[@DrCaseyPeavler]

I love pure encapsulations. Issue becomes for the cancer patient who needs truly high dose. Pure is also let’s face it very expensive.

[@debiwillis9045]

​@DrCaseyPeavler what if your pineal gland is calcified?

[@troychristensen8016]

Where in video do you explain if and how melatonin blocks sugar uptake by cancer cells ?

[@DrCaseyPeavler]

That should be one the following video! Melatonin KILLS Cancer: REVERSES Warburg Effect & INHIBITS Glucose kzbin.info/www/bejne/nmXNZpSQd72Anck

[@littlelulu7403]

Can you recommend what brand of melatonin ca we buy?

[@DrCaseyPeavler]

I don’t generally recommend supplements unless in an extreme case like cancer.

[@lookfeelbehealthy6320]

Did I miss dosage amounts?

[@DrCaseyPeavler]

I do not give them in the videos. It would not be responsible for me to give dosages. Context is everything and the dose, timing and scheduling needs to be discussed with a healthcare provider. Unless I had cancer, I would not recommend supplements. You can make nearly unlimited amounts if you do the right things. Check out melatonin videos 1 and 2 in this series if you missed it.

[@debiwillis9045]

Look up Dr Doris Loh

[@kessastratton5773]

How much melatonin should I be taking for stage iv breast cancer and what brand?

[@DrCaseyPeavler]

First off I am sorry that you or someone you love has stage IV cancer. The dosing, timing and scheduling should be between the patient or client and the doctor. What I will say is that I have seen as little as 30mg nightly to 180mg nightly, upwards of 120mg 4x/day. However some of the folks on here are using gram quantities. The safety is unparalleled it seems.

[@rredding]

The body breaks down melatonin. However, in some that process is minimal. It is possible to check for that by taking an amount of Melatonin and test the remaining concentration after some time. Any thoughts about that?

[@DrCaseyPeavler]

What’s wrong with melatonin being broken down? Melatonin metabolites (breakdown chemicals) have even more powerful effects against cancer than melatonin. What you need is a steady stream in the system. And that is completely dependent on your light environment.

[@rredding]

@@DrCaseyPeavler Perhaps my wording was wrong, not clear enough. I understand that red light therapy will raise melatonin in a natural way. However, sometimes megadoses melatonin are given in pill form. Breakdown of melatonin is natural and normal, but in some persons this breakdown occurs only minimally. So, in that case when taking 20, 50, 120 mg or more per day, melatonin will stack up. I fear this is unhealthy. So, if I were prescribing megadoses of melatonin, I needed to verify that melatonin breaks down as expected. Any ideas on that?

[@DrCaseyPeavler]

I hope my previous comments didn’t come off as harsh. Was trying to be provocative in my question. I am not aware of any test available to clinicians that would be able to detect melatonin metabolism. I’m guessing you would be taking about enzyme polymorphisms which would either accelerate or inhibit metabolism.

[@James-lb3jo]

Is the melatonin orally ?

[@DrCaseyPeavler]

Depends on your context. For general health prevention, would recommend you watch melatonin videos 1 and 2 and maximize endogenous production. If you have cancer then yes, oral melatonin could be a huge benefit.

[@riumudamc4686]

What would you consider max aunkight exposure for prevention?

[@DrCaseyPeavler]

Great question. What is your latitude/location? Skin type?

[@riumudamc4686]

@@DrCaseyPeavler thanks for the reply Dr. Peavler. 42° N and light/medium complexion

[@DrCaseyPeavler]

Start slow, start with AM light sunrise to 10am with whole body exposure, then again around 4pm to 630pm. Those times the UV is relatively weak and you get mostly visible and infrared light. This will start to precondition your skin to be able to handle UV better. For 11am-3pm start with 10-15 min of exposure. Slowly titrate up with a goal of 30-60min. Try to never burn. Track vitamin D levels via serum testing.

[@riumudamc4686]

@@DrCaseyPeavler thank you again Dr. There is minimal sunlight for several months of the year. There can be consecutive days without sunlight. What do you recommend?

[@DrCaseyPeavler]

If you are ill, move to lowest latitude to zero as you can. Low population density. If you are not ill you can experiment with PBM and artificial UV, but you cannot no how good the company is, recreate the sun.

[@andreadamascceno2139]

Does melatonin lower the blood pressure too low?

[@DrCaseyPeavler]

I have not seen that be the case. Does it affect your BP?

[@mj625]

I know you're probably not supposed to talk about dosing, but where does a person start when you're talking about prevention vs trying to treat cancer or other disease?

[@DrCaseyPeavler]

It’s frustrating I know but these kinds of things have to be between a doctor and patient. For good reason mostly. What I would say is, maximize endogenous production. That is video one and two of this series, discussing circadian released melatonin and mitochondrial created melatonin with exposure to sunlight. Start there. If you have a severe disease you would supplement in discussions with your doctor on top of my above recommendations.

[@DrCaseyPeavler]

That should at least get you started.

[@mj625]

@DrCaseyPeavler appreciate the specifics you gave me. I haven't seen those yet but will watch them. Something I will say about your videos is that they go much deeper than other channels. There's a lot about the physiology I don't understand, but with enough persistence, I will get there. Thank you!

[@Truthseeker552]

@@DrCaseyPeavlerlet’s not be disingenuous here. No doctor I know nor have ever visited, including oncologists, would ever recommend melatonin. They know nothing about it, as do 99% of doctors. So telling people to consult their doctor has the same result as never taking melatonin for cancer.

[@DrCaseyPeavler]

You will get there. And I’ll get better at teaching. One thing I would say is that this channel builds on itself. So if you start at the beginning of the cancer as a metabolic disease playlist and watch it through, I think that would make a huge difference.

[@user-si6hd6hd5g]

How much melatonin should a woman take to prevent cancer? I am a cancer survivor - Hodgkins Lyphoma stage 2 b.

[@JodizzleSlotRizz]

I know. I have been taking 10 mgs of melatonin daily since 2017 and I have had skin cancer 4 times and I am having a endometrial biopsy in about a month. So, I would definitely say it needs to be more than 10 mg daily.

[@ws7001]

@@JodizzleSlotRizzcheckout Dr Doris Loh. She recommends ~4grams for viruses and at least 2 grams for cancers but in divided doses. No one really knows what doses.

[@DrCaseyPeavler]

Thank you to everyone sharing their experiences. First off I am grateful that you are a survivor. The dosing, timing and scheduling should be between the patient or client and the doctor. What I will say is that I have seen as little as 30mg nightly to 180mg nightly, upwards of 120mg 4x/day. However some of the folks as you see are using gram quantities. The safety is unparalleled it seems. I still say whatever you supplement should be IN ADDITION TO max solar exposure and intracellular production and perfect circadian rhythm to maximize endogenous nocturnal pineal release.

[@user-si6hd6hd5g]

​@@JodizzleSlotRizz thank you for sharing! All the best with the testing.

[@user-si6hd6hd5g]

​@@DrCaseyPeavlerthank you for your response, Dr. Peavler. Your videos are amazing. I wish I would have learned these things back when I was going through chemo and radiation. You're doing good work!

[@raykinney9907]

QQQ: In the tumor environment acidity, is it not lactate elevated, but not really lactic acid?

[@raykinney9907]

This question came up to me at about 4:20 in the video.

[@DrCaseyPeavler]

The terms are interchangeable. Lactate + H+ is lactic acid. Does that make sense?

[@raykinney9907]

@@DrCaseyPeavler Yes, so much slips past my grasp. Thank you.

[@DrCaseyPeavler]

It’s ok man, this is complex stuff. We are all learning…

[@markaguilera493]

If ir is just another word for heat, would hot water baths or saunas boost melatonin?

[@DrCaseyPeavler]

As far as I know the studies are not done, and it does pose an interesting question. But what wavelength of IR is coming off a hot bath or Finnish sauna? I think sunlight is your best option, probably near-infrared heat bulbs are a decent second option, full spectrum IR sauna, and photobiomodulation panels as next best options. But the research needs to be done to get more clarity on this.

[@belligerentmovement8]

Should we just be relying on sun exposure for melatonin or supplements as well?

[@DrCaseyPeavler]

Context is king. Unless you have a severe disease you should be trying to maximize endogenous production. If you have cancer, risk vs benefit argument needs to be had with a healthcare provider. But even if you supplement, would recommend to maximize your own internal systems.

[@belligerentmovement8]

@@DrCaseyPeavler thanks, I greatly appreciate the info. The healthiest times I can remember in my life are the times I got the most sun. Your info has inspired to start sunning myself as much as possible again.

[@DrCaseyPeavler]

Don’t burn but yes, I agree that is the first order of business. I am glad you are enjoying the videos!

[@belligerentmovement8]

@@DrCaseyPeavler got it no burn, thanks.

[@DrCaseyPeavler]

Happy to be of assistance

[@JH-qy7rc]

👍

[@DrCaseyPeavler]

Thank you for your support!

[@economicfreedom8591]

Interesting research, indeed. A company called "Ascent Labs" markets a melatonin nasal spray that is supposed to be more highly absorbed than oral products such as tablets and gummies.

[@raykinney9907]

Hmmmm, and I wonder how many mechanisms of action of melatonin might be beneficial to improve mucosal immunity functions, at this respiratory first line of defense?

[@DrCaseyPeavler]

As with everyone, unless in extreme cases, I am going to recommend you maximize endogenous production by leveraging light and dark. When you make it in every mitochondria of every cell, absorption is irrelevant. It’s already where you want and need it to be.

[@raykinney9907]

@@DrCaseyPeavler Yes, such a point!

[@DrCaseyPeavler]

Gotta keep it real ha.

[@davidvandeusen3424]

​@@DrCaseyPeavlerdo to provide on line or in person medical care