You are very welcome Ray. Thank you for your feedback and support!

Yes I could imagine how frustrating that would be to watch. Hopefully things will change in the very near future

Wow genius, I had never heard of it. Commercially available?

@DrCaseyPeavler Probably not commercial or clinically tested yet, but you can Google for the synthesis.

You are very welcome! Thank you for your support

You’re welcome!

Great question. To be determined. My gut tells me these natural inhibitors will not need to be pulsed like the pharmaceutical ones, but we shall see.

Yes because at low doses it’s exactly what you said a powerful antioxidant and can actually help cancer grow. At higher concentrations it has a paradoxical pro-oxidant effect and kills cancer cells.

There are probably full spectrum thyme extracts but then you may want to combine that with a betulinic acid supplement for synergy. Normally not safe to consume orally from what I understand

From the research it seems all cancers are subject to reliance on glucose and glutamine. Dr. Seyfried and his group have not been able to find a cancer that wasn’t yet.

I personally had only used thymol in the setting of dysbiosis or fungal infections prior to seeing these papers.

Although unfortunate, this is not easy science to understand or grasp. You thought you were doing something good for yourself and in some way perhaps you were. Probably best not to beat yourself up about what was, but focus on what you can do now.

Thank you for your kindness. Unfortunately not, it’s my personal beast that keeps growing every day. It’s more than 1000 slides at this point and is multiple GB in size.

@@DrCaseyPeavler exponentially growing. Onward and upward into the light.

These were done comparing mmol concentrations so it should be apples to apples. Pun intended given we are talking about quercetin. I think EGCG seems to be a stronger inhibitor of that specific enzyme but quercetin is unbelievable and should not be discarded because of that one study. I agree that using other routes like lipsomal technology is a great idea.

@@DrCaseyPeavler Hmmm, but would liposomal change any functionality? I doubt it would, but is there research on possible differences for mechanisms of action?

I imagine it would be yes

Yup I am very familiar with deuterium and deuterium depletion therapy. I think it’s an easy adjunct to metabolic therapy given you’re already on a ketogenic diet.

I am really sorry about your mom. That is interesting what you say about wound healing…the goals related to prevention are different from those in metabolic treatment. Perhaps you are overdoing it like you said. If you aren’t focused on circadian biology, improving solar exposure, and perfecting sleep that could be a couple projects for you to improve your health.

@@DrCaseyPeavlerThank you for your suggestions! I had not thought of those factors that are important as part of having a whole intregrated approach. I've been watching a lot of your videos only recently having become aware of your channel (and catching up on all of this amazing and powerful content). I fully believe in the integrative molecular aspects and biological pathways approach for preventing and treating cancer, but it seem to me that most integrative doctors do not have a super indepth undertstanding of the mechanisms and pathways like you do. The power of synergy as you mentioned makes a lot of sense and could have immense potential to helping people to fully recover. I know someone who had gone to an alternative clinic in TX but seems to have been disappointed. I will make the suggestion he contact you for your expertise if your taking new clients. He has had prostate cancer with a radical prostatectomy but still has a lingering but low PSA level and wants to see if it can be totally eliminated. He's on a lot of supplements though he isn't really sure what he should be taking and at what dose, kind of a hit or miss approach of all the things he's heard of. That makes me somewhat concerned that if it's too much of one particular thing it could be counterproductive, like for instance high doses of EGCG can be hepatotoxic in some people. He's in CA and if you offer the video consultations that would make it easier for him if he won't need to travel to FL.

That is the issue. To be determined and there is only one supplement I am aware of on the market.

It is my genuine pleasure and honor to share this. God bless you also

He's a good man and doing incredible work but unfortunately the majority of the masses do not appreciate hearing anything with science which is really part of the essential proof for all this.

Thank you for your kindness and support! I would love to reach more people and hopefully hit a critical mass of people who know about this science.

No problem. 6-diazo-5-oxo-L-norleucine (DON).

Yup but there are several other water researchers besides Gerald. They found similar things but called them coherent domains instead of EZ. The experiments we are waiting for is that same experiment with DDW per Jack Kruse

That's awesome both that you beat it and also help others! My aunt passed away from ovarian and my other aunt got it too but was willing to try a lot of anticancer supplements and is alive today cancer free after more than 5 years and didnt go through chemo because she was terrified of it, though she did have surgery to remove the main mass.

Amen so many people have been healed from ovarian cancer! So encouraging!

I am really sorry to hear that. GBM?

Thank you for sharing!

Thank you for sharing. The NMDA receptors would make sense for glios for sure. All of these transporters are not located in all places in the body. It would make sense to body map where each glutamine lie and could potentially target specific channels for different cancers.

Melatonin, vitamin D, quercetin, thiamine all inhibit PDK!

@@DrCaseyPeavler translating that list: go for a long walk outside, with a beach as the target, and bring a good portion of slightly grilled salmon with capers for picknick :)

I love Jane and her book. I have not seen ursolic acid having an effect on glutamine uptake personally. I have seen it blocks SLC7A11 the glutamine/cysteine antiporter which is a crucial pathway to inhibit as well. Do you have the paper or reference for what she says on page 368?

@DrCaseyPeavler I tried to send a link to my Facebook page in your comments with the Pic because U tube wouldn't let me download the Pic. The sentence is (included Under Radicicol) A combination of ursolic acid and resversatrol or ursolic acid combined with curcumin prevents glutamine uptake by the cancer cell. Footnote: Stefano Tiziani et al. Combinational treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulation of cancer cell metabolism Precision Oncology volume 1, Article number: 18(2017).

Curcumin and resveratrol for sure do block glutamine uptake. That much is clear. Since it was a combination it would make sense but would not allow proper analysis of ursolic acid alone.

Thank You again doctor Casey. Your on the right track.

Merry Christmas 🎄 🎁

Thank you so much for the update. I think disease stability is a win. Of course I would prefer you to be NED. What PPM DDW are you drinking and how much?

@@DrCaseyPeavler Well I am ordering water from two sources, one is 5ppm and the other is 10ppm, but I am not drinking it straight, I am diluting. Not being super scientific, but I will consume 1 16oz bottle of 10ppm per day in place of other water and fluids. Also had my tap water checked and it's 139ppm, which is pretty good (St. George UT). Finally I drink a lot of raw organic milk and Petra said they tested grass fed milk at 138ppm, so pretty good as well.

139 for tap water is not bad! But what you are doing is clearly working from a deuterium standpoint

@@DrCaseyPeavler Yeah, not a ton out there. It would be nice if we had more food and water supplies tested. I was drinking at lot of Topochico and Mineragua bottled water. Would like to know what they test at, but I am guessing closer to 150ppm. We'll see if it makes any difference with cancer, that's the ultimate goal. Oh and I do filter my tap water with Epic Smart Filter. I would never drink it straight, even though St. George water is pretty decent.

@@allenbrost9564 Yah, those grass-fed critters have done a lot of the work to reduce deuterium from getting into mitochondria, and more keeping the blood levels higher but stable. Apparently, a lot more to the story of what benefits may be happening with energy flow and structure water in blood flow. Eating the benefits already done by the animals, apparently can be a 'led up' for our own physiologic efforts to filter the deuterium from harming the electron transport chain.

You are very welcome! I hope it is useful to you!

@@DrCaseyPeavler It definitely helps! Following your video i understand what additional supplements I need to. Thank you again!

I would be happy to test that out!

Yup! 💪

One study I saw showed 0.7% ursolic acid in rosemary leaf. I got the powdered version to ingest the whole powder since its not water soluble and brewing a tea from the leaf would not extract the ursolic acid very well. There don't seem to be ursolic acid supplements ready available at a low cost, so its nice that the rosemary leaf powder is very low cost. I was using about 2 to grams a day, getting about 15 mg to 20 mg of ursolic acid. I also had gotten my aunt on a rosemary extract after her ovarian tumor was removed and she did not have a recurrence so it might have helped along with the other supplements.

@brienq I tried the Rosemary extract, but it wasn't the same. I get ursolic acid from Supersmart USA as they have a company in the UK as well I think. I like this brand. It isn't that pricey, but the quality is worth the price. I believe it makes a difference.

@brienq I also take milk thistle as I think ursolic acid can be hard on your liver. I didn't even take the recommended dose on the dose bottle, but just what I could tolerate, and it was still strong.

@@rosemaryflee I think you're right about that it might affect the liver. I had to stop taking it after I seemed to develop an allergic type reaction after being on it for months. My hands broke out in painful and itchy hives, almost like sores, and I had them for months not knowing what was causing them until I thought to try stopping the rosemary and then within days they started to go away. It might be the immune system being affected by something in the rosemary,maybe the ursolic acid or the carnosic acid/carnosol, something else in it that then impacts the liver (rosemary is loaded with essential oils which in general can be linked to sensitizations). I'm not exactly sure how the liver would be impacted but there are idiosyncratic autoimmune type hepatitis (immune mediated liver inflammation) that could be possible, and not really knowing really what was going on physiologically, I'm just speculating with this.

I had heard about it from Vince on MetCancer but I not know the case well.

You are very welcome! It’s my pleasure!

I am so happy you are doing all of that for yourself and learning all that you can! I know the videos are complex but they do build on each other so watching them in order can help! Repetition also helps. Be gentle with yourself this is not easy. I do want to do some more simple videos once all this science background is laid down. When you are outside of “the system” you need to back up any claims or ideas with literature so I stay pretty close to the research.

There is actually a ton of literature for ivermectin and cancer, not as much as mebendazole but a lot. I haven’t seen that particular mechanism but I’m not finished doing my deep dive research.

It’s not hard to do keto. Why wouldn’t you do that if your life depended on it? DON is next to impossible to get in the US. Fenben and IVM are easy to get.

@josephschmeggins6311 I am doing Keto and taking supplements. I follow Dr. Casey's research and take a lot of his research and apply it. Keto has definitely helped me tremendously I feel great. It's simple to stay on Keto. However I wouldn't say it's easy. As a former sugar eater sweet tooth guy. I miss being able to have my pies and sweets. Yes there is sweetner alternatives but the recipes just aren't as good. Haven't found anything close to a good cherry pie, Dorito or an Oreo cookie. I have given up all these foods. I wouldn't say it is easy especially during the holidays. I have reserved holidays to have a cheat meal. My main point is if there is a supplement to block glucose to Cancer Cells allowing us to have a desert occasionally then I would like to have it to safeguard in the event I have a sweet. I already do Keto and take glutamine blocking supplements. I am not advocating for people to have a pill to just eat however they like. I am simply saying it would be nice to have a pill to safely eat a sweet or carbs occasionally

💪💪 tip of the spear!

Hopefully much more than that! Hopefully they will get industry out of the regulatory bodies, and in general push HEALTH and prevention.

It’s my honor and pleasure!

I would probably supplement with EGCG and drink green tea if I had cancer. If I’m looking at disease prevention just drink the tea 🍵

@@DrCaseyPeavler Thank you so much for your info. Happy holidays!

You are very welcome!

What do you mean?

Very kind of you! Hope you enjoy the videos!