MTHFR - High homocysteine and Low homocysteine

Knowing your homocysteine levels is essential before starting to fix methylation.
Homocysteine levels should be approximately 7umol/L.
In this video I discuss the reasons for high homocysteine and the reasons for low homocysteine.

[@titaniummaster1532]

This woman is brilliant and does a very good job explaining something potentially complex. I’m in the process of figuring out my current situation. I will watch all her content.

[@SatumainenOlento]

Wow! How well explained and shared! This is The Best information which I have found to this day on what is really happening in the body and why it is much more complicated problem to solve than anybody dares to say. Thank you thousand times for sharing! So helpful! ❤❤❤

[@kathysharp7551]

Fantastic info! You are the first resources I have found that actually understands this stuff. I recently learned I have the MTHFR C677T homozygous mutation. But, I also feel as though I tend to have high inflammation. So, now I know to get my homosistine levels (and maybe methalfolate, B6 and Choline levels...I'll look into wether that is helpful and doable) checked before taking action. Other doctors just say take this or eat that. They don't seem to understand the complexities that you understand. I also saw in a comment that you see patients globally. I will hang onto that info too. Thanks!

[@JoanneKennedy]

Hi Kathy, thanks for your message. I'm glad you found it helpful. I'm going to be doing a lot more youtube videos soon on methylation, histamine, gut and oestrogen....and much more!!!!!

[@hartmutneuendorf4915]

Wow, first class information

[@fromadem]

thank you wonder woman

[@janmartell9792]

Yes, this is so complicated. My homocysteine levels are low and I feel very unwell. I have wonderful drs in MI and I know they will figure it out.

[@Johann_]

Very interesting! Thanks! Where can I find this pathway planner? Is there a downloadable version?

[@toneman8478]

What test do you recommend to show how my methylation pathway is working and what nutrients are needed to correct an imbalance

[@M_K_M_K_M_K]

Hello Joanne! Thank you so much for this video.... I was wondering if you could help me see what I should do.. I am a 32 year old woman. Homozygous MTHFR, a lot of gut issues (strongly feel it might be Sibo), skin issues (acne), long history of health issues. Right now I am having to start B12 supplementation for low B12 (also I am fut2 non secretor meaning I can’t use all of the B12 in my blood?) and I have high homocysteine (43.6 umol/l). I think this correlates with what you are saying... My need for eating a lot of folate, B12 supplementation and then hopefully B12 will go up, and homocystein down? I have to avoid gluten and dairy and too much sugar, and that helps my gut usually as well. If I don’t (like the last week) it gets bad fast. I hope you can shine a light on this for me! I am terrified of B12 because it gives me horrible cystic acne, but I understand health comes first. Thank you and greetings from Europe! 🌼

[@ninavaldi2032]

Please, what's the best diet or way to increase homocysteine levels? Should I be supplementing with b6 and not the other b vitamins then?

[@TimeWaveOfficial]

can we get the wall picture somewhere?

[@Hottietatsy]

Great info! But where do I go from there? I don’t know what my homocysteine level is but I have SIbo, dysbiosis, Lyme, MTHFR. I do not respond well to methylated b vitamins and majority of supplements that are pathogen killing. My suspicion is inability to detox. Not a single doc was able to help me get my health on track and the ones I saw are well known and highly regarded.

[@BizKit167]

I have 13.5 homocysteine. How long after starting b6, folate and b12, with tmg, to bring my homocysteine level to 7?

[@bellazest971]

Hi Joanne, curious to know how someone that has histamine intolerance can heal the gut if bone broths and fermented foods are not tolerated. Thanks

[@JoanneKennedy]

You can use nutrients including glutamine, zinc, Vitamin A and Vitamin D to heal leaky gut :)

[@ninavaldi]

So please suggest how to help treat low homocysteine? I’m reading conflicting info stating too much b vitamins can drive homoscyteine down? So is taking B6 recommended for Low HMCYN? Then I hear about b6 toxicity. So complicated

[@fooballers7883]

To understand this fully...u need a degree in Biochemistry....after 50 yrs... I am studying this again and drawing the pathways...thanks for the memories of my youth

[@dmahadeo]

Where can we get a copy of your Pathway Planner? I think it's brilliant.

[@stephenleighton4050]

Hi... yes ... I am also interested in kiwi g where I can purchase that poster??? Any help would.be greatly welcomed

[@amandaradcliffe5391]

Thank you for your video. What would happen if someone with MTHFR mutations supplemented with high levels of methyfolate, b12 and b6. Could that possibly use up too much homocysteine and make them low?

[@Needless2say]

I use bigger doses of methyl B's and feel terrible when I don't. ( interestingly my bad health symptoms decreased after finding hidden tooth related infections and removing sugar from the diet.

[@TheShumoby]

My homocysteine is 6.4. Is that too low? I have a heterozygous mthfr 1298

[@megancangey6617]

Mthfr- can it cause high or low homocysteine? Or just high?

[@King311___]

My level of homocysteine is 24. Dunno what to do.

[@ninavaldi2032]

Can gut health increase low homocysteine levels?

[@titaniummaster1532]

It looked like poor gut health raised homocysteine levels 9,10,11…… I’m trying to figure this out to!

[@annaolsson8269]

I got low homocysteine, 3.7. What can i do to improved them? My doctors says it good to have low homocysteine. But im not sure. Ive been sick my whole life and im 27 years. Please can you give me some tips to help me to raise my homocystein levels. Ive tried SAMe supplements and my body respond very good. Im not on SAMe now. Kind regards from sweden

[@JoanneKennedy]

Having low homocysteine is not a good thing at all. It means that you have a lot of inflammation and oxidative stress that needs to be treated. I see patients globally via Zoom. If you would like to make an appointment you can do so via my online booking system on my website. www.joannekennedy.com.au

[@toneman8478]

@@JoanneKennedy Do you see any relation with Homocysteine and high ferritin levels?

[@JoanneKennedy]

@@toneman8478 Yes. If your homocysteine is low this can be due to gut inflammation which reduces iron absorption

[@toneman8478]

@@JoanneKennedy well im guessing mine will be possibly low since my ferritin is really high? Wait that doesnt make sense.. If your ferritin is high wouldn't that increase iron absorption in the blood?

[@JoanneKennedy]

@@toneman8478 If ferritin is high then it can be an issue with liver inflammation or megaloblastic anemia

[@fj2774]

I have a 6 mcmol level is that normal or low

[@JoanneKennedy]

6 is fine

[@jakesanin1]

I have MTHFR,I tryed supplement methalfolate 1mg,I felt so bad,i stoped,I dont know what to do ,my doctor doesnot know about it

[@RG-yz8ov]

I'm homozygous mthfr and homozygous comt so i need more methylfolate but too much methyl and It effects comt anxiety ect. You could try b12(adenosylcobalamin) and b9 as (folinic acid) not folic or methyl.

[@RG-yz8ov]

Also tmg brings down reduces homocysteine. If going methylfolate then try lower 400 micrograms every 2nd day 🤷‍♂️

[@super-pp]

my husbans' homocyateine lever is 20.54😱， i'm so worry about him. i need to buy multi B to him?

[@victoriarimko5226]

Do not buy multi B. He needs methyl-B12, methyl-Folate, and B6 (P5P). These are special highly absorbable forms. As far as doses you have to look them up.

[@super-pp]

@@victoriarimko5226 thx man for your kindly suggestion

[@RG-yz8ov]

Methyl donors so tmg would also help. Yarro do a b-right supplement where multi b are in there basic forms many others do too. If he has mthfr snips then there is also facebook groups you can join that have some info.

[@titaniummaster1532]

@@RG-yz8ov jarrow b-right ?

[@RG-yz8ov]

@@titaniummaster1532 yep I herb stocks it Jarrow b-right thats the one cheap too. Many around now.

[@ke2delight]

As it turns out MTHFR is not affecting homocysteine.