My ANTI-AGING Evening & Morning Routine To Look 18 Again (Living To 120+) | Bryan Johnson

Biological aging is a super-hot topic these days. With so many people test-driving different anti-aging protocols, we now know that it’s possible to turn back the hands of our biological clock. Now it’s time for the next question-how far will we go? And to what extent can we use AI and other technological advancements to help slow the aging process?
Today on The Dhru Purohit Podcast, Dhru sits down with Bryan Johnson to discuss how he’s slowed his pace of aging to that of an average 10-year-old, how he’s optimized over 50 biomarkers, and why he feels the future of humanity is in desperate need of a new operating system.
Bryan Johnson is the most measured man in human history. He’s on a quest with his Blueprint framework to reverse his biological age and show others how they can do the same. Bryan founded Blueprint to create a world where humans and technology seamlessly collide to level up human potential by leveraging advanced neuroscience, machine learning, and engineering.
Johnson is also the founder and CEO of Kernel, creator of the world’s first mainstream noninvasive neuroimaging system, and OS Fund, an investment firm that focuses on backing entrepreneurs who are leveraging breakthroughs in fields such as artificial intelligence, biotechnology, robotics, space exploration, and other frontier technologies. He is also an outdoor adventure enthusiast, pilot, and author of children’s books Code 7 and The Proto Project.
In this episode, Dhru and Bryan dive into:
-Bryan’s evening routing and why he places such value on sleep
-Why Bryan fired “Evening Bryan”
-Bryan’s early life experience and how it influenced his work and health journey
-Understanding that temporary pain can lead to long-term happiness
-The Blueprint framework
-Key events that have taken place to make society so sick
-How data collection can help resolve the problem
-Top-line biomarkers for aging
-The role of calories in diet and healthspan
-How Bryan achieved and continues to maintain a 100% sleep score
-The “SAD” score (self-aided destruction)
-Posture
-How Bryan helps his son follow the Blueprint framework
-Addressing Elon Musk’s perspective on longevity
Also mentioned in this episode:
- blueprint.bryanjohnson.co
- www.rejuvenationolympics.com
-The SAD score (Tweet): / 1644742156178042882
-Sign up for my Try This newsletter here: dhrupurohit.com/newsletter/
For more on Bryan Johnson:
-Instagram: @bryanjohnson_
-Twitter: @bryan_johnson
-KZbin: @BryanJohnson
-Website: www.blueprint.bryanjohnson.co.
This episode is brought to you by:
-ButcherBox: www.butcherbox.com/dhru
-InsideTracker: www.insidetracker.com/DHRU
ButcherBox has a variety of different boxes, and you can choose your box and frequency. For a limited time, you can sign up today and get two pounds of ground beef free for a whole year PLUS $20 off by going to www.butcherbox.com/dhru.
InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they’re offering my podcast community 20% off. Just go to www.insidetracker.com/DHRU to get your discount and try it out for yourself.

[@DhruPurohit]

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[@organizer14]

How will you account for purpose vision and reason to live because quantum physics demonstrated non linear factors have tremendous impact on any results!

[@dm7232]

😂

[@rics1883]

No

[@laruealegria4450]

SLEEP IS SO IMPORTANT FOR MENTAL AND PHYSICAL HEALTH.

[@rics1883]

@@laruealegria4450 no shit sherlock

[@internetcelebritycentral]

As a medical student, scientist, biology nerd and life apprentice that i am, im amazed by this, people still dont understand how big is whatever this man is doing. Hes already a billionaire and has no reason to be doing anything he does, and still he is up for the challenge using himself as a human trial for all this new science. This man deserves to live 200 years more with all the money in the world. God bless him. Wish him the best of luck.

[@user-rb9kp6vr4o]

why doesnt he just invest in longevity research?

[@MsBettyRubble]

​@@user-rb9kp6vr4oBig Pharma and the food Industry are known to manipulate results. Clinical Trials can contain bias. He has control over the purity if the data by doing it himself.

[@rianeon]

@@user-rb9kp6vr4o he probably did theres something called privacy

[@barbarafairbanks4578]

@@user-rb9kp6vr4o he IS!...and in a very personal way.

[@beejumittahb8527]

Why should we be so happy that he can live even longer. Do we not think we as a species live long enough See our relationship with each other the poor or the destitute homeless that we step over on our high streets See our relationships with other nations that we extort and dominate See our habits with nature and the near obsolescence of other lifeforms Surely we need to restrict human lifespan limit our heinous habits!

[@nicetomeetyou610]

Bryan is so honest, humble person like rarely found on the planet earth. Huge appreciation.

[@That_Guy_111]

I find it interesting that Bryan Johnson is obviously and genuinely trying to find a better path forward that potentially could benefit all humans in the future yet 90% of the commenters have this crazy urge to find or say something negative about him.

[@iloled2924]

That’s just internet discourse in general. I’d mostly ignore the negative comments. The people that post them don’t matter. Most of them are nameless, faceless, insignificant trolls with nothing of value to add, and project their own inadequacies and insecurities by barking at the world around them.

[@emh8861]

They’re just bored.

[@silvio.r8443]

It's the high achieving nerd syndrome. They become a target for insecure bullies.

[@guillermocalvillo3102]

It's the mind and the ego that feels insecure because they themselves aren't reversing their age. Or even taking care of their bodies in the first place. So they shoot this down in an attempt to justify their own habits.

[@omararreola5449]

They are unhappy with themselves

[@dianeledoux1064]

Dhru, I have listened to 4 or 5 different interviews with Bryan, and you are the ONE who was able to bring the best out of Bryan, never showing him negatively, never judging whatever he does. You did the best interview,. The other podcasts, I was always able to see Bryan positively, because I totally understand what he is doing, even if often they were not showing some of his routines in a positive manner. Bravo Dhru.

[@eneneejembi6226]

Yes 🎉🎉🎉true this is the first one where host and Bryan are on the same wavelength 🎉

[@diann3880]

Bryan is a lost soul sorry

[@DGP888]

@@diann3880stop projecting yourself

[@pucie_boi]

Yea but Dhru's long drown out questions omfg get to the point man!

[@mamacrypto434]

Such a lovely human. People give him such hateful comments. He is so honest, raw and vulnerable with this conversation. You have a beautiful light within you Mr Johnson.

[@ingainge3146]

This guy can change your life if you get into his philosophy. Not about what he eats but his life perspective. He is absolutely fantastic in field what he is promoting- sleep and healthy eating! ❤

[@RAJOHN-ke7mc]

Taking hundreds of supplements is just plain silly.

[@Jamamaw55]

Science says different. Thank you for sharing all the truths Brian.

[@tinat5484]

Bryan alone has done and will do decades worth of bio research.

[@RD-zw5yd]

It is so refreshing to see people like Bryan who genuinely cares for humanity and puts himself out there in this crazy mocking world. Instead of appreciating what he is doing and be grateful, I see a lot of negative tweets about him. Way to go Bryan!

[@viajeraempedernida6192]

When I lie down, I go to sleep in peace; you alone, O Lord, keep me perfectly safe. Psalm 4:8

[@jameshyam8668]

Does anyone really want to live to 120 especially if you live alone, i shall be 92 in a couple of weeks consider myself in reasonable health, look after myself, eat well , you need to keep active ,a glass of red every day, try for a good nights sleep, would be happy to reach 100

[@cece3194]

I guess it depends on what I'm able to do for others.

[@Zdp24]

No I definitely don’t want to live up to 120 but I do want to stay mobile and ( hopefully ) independent until I die … I dnt know why people want to live up to 120 when most of your family members and friends will most probably have left …

[@dieste8]

The point of all this is to increase health span. Whats the point of living longer if you're stuck in bed and dependent on someone else for care?

[@user-qm6sr2pv6v]

My kids need to outlive me.

[@paulaistrate4628]

45 years old and i am in a worst moment with a lack of sleep since 12 months ago I am listening to this hoping I will get better and fix my sleep

[@MonSamDan]

Paula I'm assuming you're a woman and at 45 you are most likely in perimenopause approaching menopause. Sleep issues is one of the symptoms these hormonal changes bring. There are things you can do.

[@lisas.1002]

YogaNidra(meditation), Melatonin 5mg and a dark room helped me. Other sleep meds made things worse. Good luck sister❤

[@JanetSmith900]

I dealt with insomnia for several years. I started taking magnesium, which helped a little (magnesium glycinate). I really started noticing a difference when I started taking NAC. And I take GABA in the evening. I sleep so much better. Getting exercise helps. Cutting it sugar helps. Not overstimulating the brain helps. Follow your intuition.

[@MarcellHanson]

You got this. Stays strong. 💪🏼

[@bethanylmoody1]

Paula i have been there and feel for you. Do you have people close to you that you can share this obstacle with?

[@JanetSmith900]

I think there's a bit of a weirdness factor to this man. BUT hearing him changed my view of him to the positive. He's involved with other people trying to maximize health. His reasons for doing what he's doing are logical (to me). He's open to what other do for their health. Etc. I'm all for it.

[@joannmclean6406]

Yes, I welcome his help. :)

[@sharonkende4774]

He is a billionaire. He is a health master. He can have three heads if it is good for him

[@nancybruns9057]

0910.. Bryan in my assessment is hes on the spectrum of autism as IS Elon Musk!

[@nancybruns9057]

He overthinks and has huge personal expectations. He is absolutely right I totally agree with him with autism on the very high end which cannons us to be someone who is brilliant with a very high IQ they ramble. It takes them a long time to get to the point sometimes they have to stop and think stay tied together in the conversation. I am in medicine have seen this diagnostically

[@mariabeckwith3336]

Pretty sure most trailblazers would be considered "weird"....because they possess something the average person does not. These people absolutely amaze me!!!

[@lmb4876]

Thank you Bryan .sleep, NO alcohol, exercise, a vegetarian diet.( no tobacco.of course) not perfect but very close to living as healthy as possible

[@shaggydogfarms]

Obsession with anything I believe is bad.. When I was 40 even 50 ..I looked as good as when I was 30.. but my mom lived to 100 so its good genes i believe.

[@robynhope219]

Also nurturing environment.

[@paolacastillootoya8904]

When I had ayahuasca, after that I was able to feel what my body wanted. My tastes in food changed, I could feel when my emotions and thoughts afected y apetite and even the way I walked. I had the best nights sleep Ive ever had in my life, and it went like that for years. My doctor congratulated me on my perfect BMI and great health, its all come out naturally. After those blessed years came the year of discipline, which were a time of me not being able to maintain that state naturally, but having to adopt routines. It didnt work for long. I still feel very aware of what my body wants, but I dont have as much discipline and my desires started supoerimpossing themselves over my actual needs (the body's wishes). Im going back to being disciplined now, but I remember the "words of the ayahuasca" which I strongly feel are the key to being effortlessly conected again: LISTEN. Having said that, I admire this man, I deeply appreciate his research, his sacrifice, I wish him success, I hope I get to meet him.

[@frankhepler2643]

I think Bryan can benefit mankind much more through his thought process of how to analyze and solve the most important problems we have in our lives. Being able to share that is price less. It's not about his quest for a longer healthier life that impresses me the most.

[@Jonnaberg]

The people who don’t like Bryan most likely feel uncomfortable by what he has to say because it puts a spotlight on their own destructive behaviours that they’re not ready to part with. Partying, drinking, snacking, staying up late, over eating, smoking, going through the drive through whenever they feel like it, leading sedentary lives, not challenging themselves, not investing in their health, their skin, their mind etc etc. The work that this man is doing is awesome and he does it with a lot of grace and humility!

[@9543840290]

Today I stopped myself from going through the Taco Bell drive-thru. Victory!! 🎉🎉🎉

[@9543840290]

Yes he does 100%

[@zofiahejaz]

This guy is such a deep thinking individual..... Iam so impressed....... if everyone could self analyse themselfes and take steps towards positive change through self enforced discipline this world would be a much better place.

[@susieedminster3822]

Sometimes he is a deep thinker then other times he says totally stupid things like making up an alternate Adam and Eve story and we're all supposed to be like, "ya, wow, such a deep man." Naaaaa, he just fell off the reality train and was searching too hard for "deep points."

[@ccaselli7]

I think he just needed a good anti-depressant or something tbh. He's just extremely depressed, and so got obsessed with this anti-aging thing. Plus being a billionaire must be depressing ,for the soul. Just sharing my thoughts.😀

[@bertdog7639]

Deep thinking? No, just wealthy and insane.

[@joannsmith9]

The reason he is so trustworthy and helpful is because he isn’t sponsored by the AMA or AHA, etc. He isn’t driven by greed!!!!!!!

[@vitaleestarostin5031]

He sold his company for $800 Million, not driven by greed?

This first part about allowing the organs to choose the action (in combination with information from technology such as bio markers) is actually a concept from Taoist Qigong! The practices are called “the inner smile”, and “the six healing sounds”, and within the practices, one has the opportunity to “ask the organ” what it needs. Each organ in qigong is said to relate to specific sets of negative emotions, as they impact physiology - so when the organ is “smiled to” and asked what it needs, its inner technology can be “listened to”, but not from words, from an inner sensing. It’s pretty amazing that he came to this practice in his own way. Mirroring it with technology will be interesting!

[@ivanbaric4017]

I wish him all the best. It is not for me. Every man walks different path, but I will adopt some of his findings to better my quality of life. Bryan is a positive energy, wish him well. Sydney AUST.

[@marylowder2931]

People keep focusing on his looks, and mannerisms, instead of what he is trying to accomplish. It may “seem “selfish, but the amount of discipline to maintain his goals is astounding. He is sharing with us, a health model /plan with the help of his team, on how to reduce the speed of aging. He could just use his money and live a private life of luxury and hire health food chefs and fitness trainers, but he chose to open his research to all of us. We can benefit with some of his protocols, he knows we can’t do all of what he is doing. Thank you Brian.

[@khalilacoco4799]

Living with purpose truly makes one happy❤ I am grateful for this beautiful interview with great minds

[@poots7591]

Great attitude

[@poots7591]

I say “attitude is everything!

[@donnajohnson3334]

I never cared for going along with society. When young, I tried to enquire,see where such and such a path led others. I saw no good in heavy partying, drinking getting a body count, and destroying the ideas that came before . Sacrificing faith, hope and connection JUST so I could be totally New...never made sense. Life tries us until we find out what we are really made of at the core. Sounds like he was playing a part in Many ways.....then, he matured. This is a coming of age. Older people have hopefully learned it.

[@laurentscheercousse3173]

1:12:51 Waoh! Not only is Brian Johnson top clear on explanations but the host asks excellent questions at the very best time. THANK YOU 🙏 2.

[@bibi1199]

So grateful I stumbled upon this mesmerizing Interview. The best I've heard ! The questions were were as intelligent and enlightening as the answers.Quite refreshing to listen to a pioneer who is using his body as a lab for experimenting and not trying to sell any products or flaunt his wealth.. Inspiring humility emanated from both men. ❤😂

[@zialuna]

Bryan so reminds me of Star Trek's Data!

[@marylee2809]

Thank you for sharing your personal story in a very clear concise way! I love this interview talk!

[@luchiayoung]

First thing I noticed was Bryan’s posture. Not just “sitting up” but back muscles so strong to keep the shoulders back.

[@thaillling9369]

Incredible, Bryan is so enjoyable to listen to and reinvigorates a sense of hope I thought I had long ago, permanently lost.

[@ugofureogoro1042]

I'm so grateful to him

[@kwimms]

Hope is from Satan... you should live without hope... hope makes you a slave and keeps you clinging to clouds...

[@jessicapae9642]

I am very interested in what Bryan is doing. He is really ahead of time! I am getting older and not worried about death but I am worried about my body falling apart, not being able to do things when I was in my 30's which i think was prime for me.

[@dianiherlihy6656]

Great interview ! 🌞 thank you both! Bryan is a very special human Being i love what he is doing , súper interesting . I find him smart & sweet 🥰

[@cynthiasivak5689]

Dhru, you do the best interviews I've seen. Such great insight into the topics and people who you interview. Bravo!

[@jacquelinedella-santa2451]

what an incredible man BJ is, and a great interviewer Mr Purohit. Thank you

[@ricardoantonio8268]

Been waiting for this. Thanks Dhru. Your contents are amazing. Keep coming.

[@parikishi2979]

Thank you Drhu. You're a good host that let your guest speak, giving space and not overtalking. Appreciate it ❤

[@drfinbar]

This is a fantastic interview. I really love Dhru’s style and Bryan’s vision and courage. I am now considering how to deal with ‘evening Finbar’

[@marcela9689]

Thank you for this interview, I really enjoyed it. Thak you for asking questions with sincere curiosity and without judgment. I deeply respect Brian Johnson for his willpower, discipline and his sober mind. I have the impression that many are walking in this world partially numb because of all kinds of bad habits like what we ingest and our sleeping habits. I look up to him and I wish I could have more courage too to resist my bad eating and sleeping habits.

[@emmalibunao4369]

Bryan is so honest. The fact that he's an immensely rich person, he can't be accused of any other motive for the works he's doing. He tried to cure himself of the depression and other sicknesses brought about by bad lifestyle.

[@megancook68]

Good morning.. I had stumbled upon your podcast here with I will say out of the ones that I have watched, your interview was the easiest to listen to maybe it’s because you understood, and were truly intrigued by his story and the struggles to get to his better self. I definitely heard some of this information before on other podcasts, but I enjoy listening to him over and over because I gain something from him that has helped me…..sometimes you need to hear the message several times for it to click and make sense to you…. I sympathize with his evening Bryan; I have that same person that I struggle with.

[@bleedchocolate]

Bryan speaks my words, although he has the means to make it happen. For Life itself, my friend. Thank you 🙏🏼

[@LTPottenger]

Most of these things are just cosmetic. If you want to try to live to 120 some fasting may help, but I doubt that level can be reached by most people regardless. Some benefits of doing occasional extended fasting: High blood pressure is lowered to normal levels very quickly while fasting. Fibrosis/scarring is reversed over time. Fasting increases nitric oxide release. Fasting restores NAD+ to healthy levels. Vitamin D plasma levels are increased as fasting improves metabolic health, and vitamin D in turn increases autophagy. Stomach acid is reduced over time while fasting and can allow for the healing of treatment resistant ulcers, but some patients may need continued acid reducation medication while fasting. Telomeres are lengthened and fasting also increases anti-aging Yamanaka factors. Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. It will also remove any 'foreign material' that is not supposed to be there. Reflexes and short term memory are increased. Fasts from 36-96 h increase metabolic rate due to norepinephrine release! After 72 hours or more fasted, your body recycles up to 1/3 of all immune bodies, rejuvenating your entire immune system. Fasting can help with MS, Depression, BPD, Autism and seizures. Fasting reduces pain and anxiety by stimulating the endocannabinoid system in a similar way to CBD oil. Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer. Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue! The hunger hormone ghrelin also lowers with extended fasting and rises from dieting. Blood sugar and insulin are lowered, allowing white blood cells to move more freely throughout the body and do their job. Some viruses activate glycolosis (the release of sugar in the body) and clinically it has been shown that decreasing glucose metabolism in the body weakens the influenza virus. When you move out of MTOR your body shuts down the building blocks of the cell which are used to produce organelles and proteins. This means the mechanisms needed by viruses to replicate are by and large unavailable when you are in a deeply fasted state. What breaks a fast? Anything with protein or carbohydrates in it will break a fast. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many meds are dangerous to take while fasting. Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone. Fasting also increases insulin sensitivity, which helps with muscle building. Fasts of 36-96 will not affect short term female fertility or affect menstrual cycle. They also may increase long term fertility, especially in women with PCOS. The hormone Leptin is an immunomodulator that keeps the body from attacking itself and obesity causes leptin resistance. Fasting very quickly reduces leptin resistance and leptin levels and one day of fasting can cut your leptin levels in half and gets your immune system working properly again! Does the body preferentially prefer glucose as a fuel? No, except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose. Fasting stimulates the AMPK complex and activates autophagy. Autophagy (literally self eating) will cause cells to recycle foreign matter such as viruses and kill cancerous and senescent cells Lowering insulin via fasting virtually eliminates chronic inflammation in the body. When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with. It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency and thereby making cells better able to fight off infection. Increased mitochondrial function also has the added benefit of increasing your metabolism and cancer prevention! Fasting also releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. In fact, the biochemical regulator of BDNF production is beta-hydroxybutyrate, which is the same ketone the body produces to nourish the brain while fasting. Fasting also increases telomere length, negating some of the effects of aging at a cellular level. When you fast, this stimulates apoptosis in senescent or genetically damaged cells, destroying them. Senescent cells are responsible for many of the effects of aging and are a root cause of the development of cancer. A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs. Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia. Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. If you experience extreme symptoms of some kind, especially dizziness or tremors, then simply break the fast and seek advice. Resources: www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/ pubmed.ncbi.nlm.nih.gov/23408502/ www.amjmedsci.org/article/S0002-9629%2815%2900027-0/fulltext pubmed.ncbi.nlm.nih.gov/20921964/ www.sciencedirect.com/science/article/pii/S0005272806000223 pubmed.ncbi.nlm.nih.gov/6859089/ www.ncbi.nlm.nih.gov/gene/25712 faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10 www.biorxiv.org/node/93305.full www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/ pubmed.ncbi.nlm.nih.gov/31890243/ www.cell.com/cell-metabolism/abstract/S1550-4131(15)00224-7 repository.upenn.edu/cgi/viewcontent.cgi?article=1537&context=edissertations www.ncbi.nlm.nih.gov/pmc/articles/PMC1779438/ pubmed.ncbi.nlm.nih.gov/2518860/ pubmed.ncbi.nlm.nih.gov/29727683/ www.nejm.org/doi/full/10.1056/NEJMc2001176 europepmc.org/article/MED/22402737?javascript_support=no onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2265.2005.02288.x www.nejm.org/doi/full/10.1056/NEJMoa012908 www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html www.ncbi.nlm.nih.gov/pubmed/10859646 pubmed.ncbi.nlm.nih.gov/25909219/ www.ncbi.nlm.nih.gov/pubmed/10232622 academic.oup.com/ajcn/article/81/1/69/4607679 www.sciencedirect.com/science/article/pii/S1931312809002832 www.ncbi.nlm.nih.gov/pmc/articles/PMC5895342/ pubmed.ncbi.nlm.nih.gov/23707514/ www.ncbi.nlm.nih.gov/pmc/articles/PMC7607739/ www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/ www.clinicaltrials.gov/ct2/show/NCT04375657 www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/ pubmed.ncbi.nlm.nih.gov/15522942/ www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/ www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ www.ncbi.nlm.nih.gov/pubmed/23876457 www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue pubmed.ncbi.nlm.nih.gov/28235195/ www.ncbi.nlm.nih.gov/pubmed/24905167 www.cell.com/cell/fulltext/S0092-8674(19)30849-9 pubmed.ncbi.nlm.nih.gov/27569118/ www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/ pubmed.ncbi.nlm.nih.gov/7714088/ www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/ www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/ pubmed.ncbi.nlm.nih.gov/31877297/ www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/ n.neurology.org/content/88/16_Supplement/P3.090 www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart www.ncbi.nlm.nih.gov/pubmed/25686106 pubmed.ncbi.nlm.nih.gov/21410865/ clinical.diabetesjournals.org/content/36/3/217 pubmed.ncbi.nlm.nih.gov/20102774/ This list compiled over years of research by the user known as Pottenger's Human on youtube but feel free to copy and paste this anywhere you like, no accreditation needed! My channel will always contain an updated version of this list of fasting benefits on the community tab. I also have playlists on fasting and health topics.

[@amineb6335]

crazy work sir. thanks

[@LTPottenger]

@@amineb6335 Thanks for the appreciation!

[@Namelessforever_]

Would you mind providing a couple more bullet points here? I’m just not quite convinced. Thanks

[@joannmclean6406]

Fasting is torture to me. I've tried it and it's not worth it to me. I believe moderation is the key. Every body is unique and different. If fasting is your thing, good for you. It's not for me. Great health can be achieved through trusting God for help with our day to day diet and exercise. We should also ask God to bless our food. ♥️

[@chrish1564]

"Most of these things are just cosmetic". Yes, thank you, that was my suspicion! I'm familiar with the benefits of fasting. Thanks for all the links, I will look at all of them and am eager to check out your channel as well.

[@themiddleman781]

I am a huge fan of Bryan and what he is doing. I even plan to try his routine for a week and document on my channel. I think all the negativity towards him stems from jealousy that he has the discipline to do this and most people do not. So they want to bring him down. I find what he is doing motivating. We can't avoid death, but we can definitely postpone it and make life a little easier

[@kwimms]

Wow... try it for a week! That will make a HUGE difference. HUGE. Then celebrate with a steak and butter pie and a Bud Light!

[@themiddleman781]

@@kwimms Haha. Not sure I can do 150 pills tho

[@forknowledge6959]

The sad thing is, so many of us are stuck living in these neighborhoods around rude disrespectful neighbors making noise at all hours of the day and night. Not even my white noise routine or ear plugs will block the out because they keep intentionally making louder and louder exhaust systems. And it's like everyone I live around doesn't care. :(

[@Sun-sz4ne]

Maybe the outside noise reflects the noise inside of you which you ignore to sort it out. Just saying.. we are mirors. We atract what we are

[@SanctifiedLady]

It’s the governments plan, more stress you have the more money they make off your illnesses

[@ugofureogoro1042]

Try nature often., may try temporary soundproof a room or space

[@susanmiller7560]

I have the same problem. I've started recording people on my phone and it works like a charm.

[@SanctifiedLady]

I appreciate him for doing this because as a nurse I do everything I can the natural and healthy way as my go to. I went to Wendy’s to get a salad I forgot my lunch at home and now it’s about a cup of iceberg lettuce which is less than a cup of water, less than a cup of chil and chips $8 I haven’t been there in more than 7yrs. But I know it was a big salad for $6 Ppl look at me strange if I eat fast food because I have to read the menu Thank you for the interview, I’ve watched it 3 times already today

[@DawnalynForrest]

The reference to Goofus and Gallant made me giddy! Getting a chance to read those stories in the drs offices, we’re a “Highlight,” of life and we’re woven into my system. I’ve used the named Goofus/Gallant in teaching, too. It fits in this Blueprint philosophy!

[@suzanneoleson7580]

I was excommunicated from the Mormon church when I was 19 in 1983 and understand the personal issues discussed here. Very interesting podcast.

[@susieedminster3822]

Seems to me this dude stopped believing that his marriage was his salvation ticket and that his understanding of the Adam & Eve account is false. Seems like he is creating his own mortality as his new God. 🤔

[@SueMaha21]

The most enlightening interview I have ever seen. Thank you both.

[@bertdog7639]

Not seen much, have you?

[@lindaponder6590]

Love the Adam & Eve story. One of the meanings of the Great Sphinx of Kemet is “Your intellect should rise above your animal nature.” also.... Mind over body/matter.🥰

[@annmarieknapp]

I appreciate Bryan, and he is sharing what he does with everyone. I appreciate him.

[@christy_tice]

To get to not even needing to think about health.. we need to explore loneliness. Many ppl eat recklessly when egoic separation and the level of loneliness in the game overcomes the intrigue towards enlightenment. The illusion of separation leads to addiction.. esp food addictions. Not for everyone.. but for many.

[@LCarefortheworld]

This Bryan Johnson is on his way to achieving the thing we all thought it was impossible. What he says intuitively making sense to me.

[@SilverFan21k]

Wow Dhru this is awesome! ❤ Did not know about this video until just now. Thanks for having on Bryan Johnson and covering the topic of Longevity!

[@wood6454]

What a great interviewer this guy is. Subscribed!

[@roxykkap]

this could benefit all of us someday

[@brennanleyen]

This is the best, most relatable interview with Bryan Johnson. I was put off him when I listened to Impact Theory so I’m glad that I watched this one and was pleasantly impressed with his methods and relatability with parenthood and health struggles that they mentioned early on. I Don’t want to live forever, but I will definitely look into my SAD score and make sure I’m as healthy as I can be so that I can continue to exist. Thanks for your work to better our species.

[@rebeccamcdowell6255]

This was such an amazing conversation. Great questions Dhru.

[@paradigmshift17]

Brilliant interview by 2 genuinely brilliant minds. Bryan is heading in the right direction that our mind is our greatest obstacle - but he doesn't seem to be aware that humans have been subjected to mass mind control since the 50s or very possibly way before that. That is how we got ourselves into this mess in the first place. We have been under a mass mind-control programme (look up MK Ultra) which teaches us how to think, how to dress, how to talk, how to behave, the main culprit being the tell- lie- vision (your TV set). Once we deprogram our brains and realise that humans have been artificially conditioned, we will understand what our real priorities are and the true meaning of life.

[@deivismacas]

Very interesting take on health. I like it 👌

[@thetinmansheart]

Fascinating. Thank you both. I had never heard of Bryan Johnson before. 👍👍👍

[@kymberlybade1480]

Excellent questions, Dhru! Wonderful podcast.

[@hermes537]

Mortality is the biggest fear. Measuring fear is impossible, nor is possible to have supplements for it. An 18 year old knows almost no fear, by 21 we realise we are not perfect and it is the start of emotional shrinking for many of us. I'm trying to do with my emotions what Bryan is doing with his physical health: getting younger emotionally by reversing fear. The biggest challenge for me is that intrinsically my ego is happiest when dealing with my fears as he is the boss then. My strategy is to use fear to minimize the role of the ego in my life. Feeding the ego less and less until it is not the determining factor in my actions. This opens me to more flexible ways of interaction with people and it improves my choice of healthy habits. I get the impression that this is a better way to stay young than what Bryan is doing. His solution is a little bit typical of what America often does: deplete the planet for the few. His carbon footprint is probable the equivalent of a few thousand Africans. I still think his project is interesting and far more valid than what other millionaires do with money. Bravo Bryan

[@christinelarkin8054]

That's like saying the last 3 years were about good intentions. When so many people and companies benefited from everything that happened off the back of other people's suffering.

[@wingsphysio]

His contributions are so valuable

[@aliciablumenthal1018]

I appreciate this talk very much ! Thank you ❤️

[@fm-gamer5617]

A lot of people don’t understand that Bryan has only 5% bodyfat. If he had 12% he would look like a 20 year old. He makes everything right and look indeed young (only because of so low bodyfat he looks older but for 5% he looks really young)

[@zdenkakoren6660]

At his age you need 40y-59y~11%-21% body fat but it depends how tall is one and how active. Problem can be if its low and you eat like he does, if you trigger Keto and there is no fat to be used or carbs shure he has a bit of protein in muscle but that can be deadly....He should eat at least some fish or Protein powder i know fish-heavy metals and powder is processed but yeah

[@fm-gamer5617]

@@zdenkakoren6660 I only said that that’s the reason he looks not so young as he would if he had more fat. I know that 5% isn’t optimal for a normal human but he is taking so much stuff so for him it’s optimal.

[@barbarafairbanks4578]

@zdenkakoren6660 yah, idk where he's getting a good protein source, based on his diet. However, he seems unusually 'built' for someone whose diet 'appears to be' protein deficient (just guessing on that, but don't know for sure)...don't know what his supplements actually are🤔

[@zdenkakoren6660]

@@barbarafairbanks4578 Well if you dont do anything you need 50g of protein if you have muscle and you need to maintain it than that is equal to your body weight 70kg=70g You can have muscle something between Bruce-Lee and 2Pac when he was out from jail xD With Hemp powder you can have that + the green powders. Dont forget oils and nuts that also helps build muscle and bulk a bit. Its hard cuz you need to grind alot of greens and nuts and eat it, shure he does not have 8h job that you need to move so that helps alot. He eats like 2-3kg of this every day so he is not deficient but he needs to scan his body for stones: kidney, bladder, mouth, and even bones aka oxalate. We are like Apes/Monkeys they eat everything but Eggs and Meat is only 3% but we humans eat like too much eggs,meat,bad oils and processed food.We have grind machines so we can win at that xD From my knowledge we can eat meat (red,fish,white) 2x90g per week and 1-2eggs per week, dairy is not that good like maybe fresh Whey or Whey Isolate 20-30g per day and some mozzarella but again, rest needs to be green drink,fruits and vegetables, even bread with yeast and gluten is bad. 100g of any green powder thing is 50-100g protein vs 100g steak is only 25g. Im like flexitarian xD

[@erichines1150]

​@@barbarafairbanks4578that's a clue for me that he's actually reducing his bio age.

[@kellyjackson8266]

Fascinating conversation.

[@Cutebutnotpetable]

Thanks to Dhru and this very present and valuable interview. Just watched a recent interview with another “data bio hacker” and I wasn’t able to make it through the short interview due to interviewer’s ADHD and Ego. Thanks to both men here, you are a gift to the world.

[@marym3355]

Congratulations for the interview. Very smart and deep questions

[@donbeuch1982]

THE STATEMENT "YOU DON'T KNOW WHAT YOU DON'T KNOW "IS ALWAYS TRUE FOR EVERYONE!!

[@lindaolsen7828]

I found that low sleep feels the same, or close to, depression.

[@taffy-sophiashahbozian7327]

It’s taken years but I’ve finally learned to listen to my body When you’ve experienced a near death experience you learn to listen to your liver, kidneys, lungs, heart etc. it takes a will to live and live healthy.

[@mattng4707]

Amazing what Brian doing ...this is what we need

[@NatalieMorris-pl6pd]

My grandma is 99, one of her brothers just died at 102 and another died at 104. I think genetics has a lot to do with it. Please take into consideration that my grandmother smoke for over 30 years and is still going with all her faculties.

[@joyabia682]

Or lifestyle. What did she eat? How did she live? Was she walking a lot?

[@GlacialRidgeHomestead]

Wow. She’s lucky. My mom quit smoking at 50 but still got lung cancer and died at 66.

[@GlacialRidgeHomestead]

I bet scientists want to study her genes.

[@wickywills]

There are likely other factors at play

[@darscassel]

I bet she slept a lot😂😂😂Jk

[@lizzklaesson5983]

very interesting, would be really good if more blueprints were developed 👩🏼‍💻🌏

[@lgpop3347]

This was a great interview. Thank you.

[@RK-su4hs]

Since the very early years man has been searching for “the fountain of youth”. It doesn’t exist. We are all just fragments of Nature & subject to its laws, as is all of nature Sounds like a very sincere & pleasant man none the less

[@basketballfan5763]

At last the video that I've been waiting for I am tired of telling my boyfriend I want to live to be 110 and he's happy to die in 10 years and is only 60 I'm 50 but I look 40 I'm a girl and I've had a lot of illnesses over the years and I intend to live a long and very healthy life❤🎉

[@ginger6803]

That's the right mindset!!

[@Lauragraceabels]

Been waiting for this. Thanks Dhru. Your contents are amazing. Keep coming. , we need more of this

[@adamweah8037]

I realized that I like this guy. He does remind me of Data from Star Trek though.

[@adamweah8037]

@@Lauragraceabels Hi Laura , Are you an Expert Trading Advisor ? i just went through your channel.What are you into?

[@Lauragraceabels]

@@adamweah8037 Yes i am , My certifications are on google . you could read up by searching my name

[@horayshyt]

My grandma spent the same amount of money on cigarettes and coffee. She lived to 103 after smoking multiple packs and drank dozens of cups of coffee a day. When your number is up, it's up. It's crazy to see you spend so much money to only live 17 years longer than my grandmother.

[@threecats1605]

I agree with you! God knows when you enter this life and knows when your time to go out no matter what you do or eat!!

[@stargazerbird]

A few people have good genes but the data says living that way will be a disaster for most of us.

[@leewilcock3673]

Totally agree! My grandad smoked 60 Capstan Full strength unfiltered cigarettes per day and lived to 106. He died by falling down the stairs. Looking for an ashtray.@@threecats1605

[@healingjourneys4241]

Bryan, thanks for sharing ❤

[@lilann6120]

I know myself now… n most people would call what I ve been a highly addictive person… but what I ve learned in the last years is, that I m not… I just didn’t learn some better skills to cope and that there r parts of me gone to a wrong direction (a wrong path) in life especially as I was a kid… n these parts of me didn’t know how to treat myself right, others right n how to cope with stuff around me… now I m on these right ways n I feel so free… For example I work out, I run round in nature with my dog, I take good care for myself n others(but especially for myself) n i don’t need any drug no more… better i don’t even want them… N i really believe there has to be no force pushing people in the right direction… they would want the best for themselves if u really teach them how to do that… ❤❤❤

[@BadMommaC]

Interesting but it doesn't seem like much of a life. Planning your day around sleep I kind of understand. I sleep well for the first time in years, but if I want to go dancing, I'll sacrifice a night of going to bed late. I'll use Huberman's suggestion of getting some evening sunlight to reduce the bad effects of that.

[@user-jt1od3oj8j]

I totally agree... sleep is my number 1 to functioning well & anti aging 😂

[@henryquenin6580]

I like his emphasis on quality sleep. It's the area of healthy living I need to work on the most. I will try to model myself on his practice of a daily fixed time for sleep that is non-negotiable.

[@WomanFromTheMoon]

Golden words! Very Each one! Respect

[@TheMrKlassy]

Love the blueprint but to me, he looked younger in the comparison photo of him before starting the experiment.

[@raspberrykissable]

I think if he gained a little weight he would look younger. He’s super lean.

[@sashanealand8315]

he was younger obviously

[@TheMrKlassy]

@@sashanealand8315 obviously

[@campersruincod6134]

It’s because his body fat % is so low.

[@barbarafairbanks4578]

@TheMrKlassy Really? What photo? Was it on here? I totally missed it🙃

[@Runastasis]

Is life just about living as long as possible, if that’s all that you focus on your whole life, is that living? I dont know...

[@omararreola5449]

Everyone has different realities and has a different conceptions of happiness

[@ionagibbons9906]

Hi I can connect with this idea that the body takes over your best interests because from my 40’s things started to happen to me that felt like my body did a take over with me to change life style and it used pain as my stick. I used to smoke and I did manage to find my own button in my head to stop smoking and turn that off and I couldn’t work out why I thought if I didn’t smoke I would put on weight etc when I had no side effects or cravings. So that was the first time I realised my body had its own operating system that was not what my personality thought. But I still used wine mist evenings with food to relax. I figured giving up smoking was my only major vice so figured no more work to do! But little did I know that my body had other ideas. I got a virus out of the blue sick for a couple of weeks so couldn’t take any wine. But after a couple of weeks figured well better now let’s return to previous stress busting techniques ie a glass of wine. But as soon as I took a tiny sip it was like a knife had been stabbed into the top of my skull. I was so surprised never had this before. Tried another sip sake thing. Concluded I still wasn’t better yet so waiting a couple more weeks. Got the wine out again and the same thing happened. Absolutely no knife pains otherwise only as soon as I put wine in my body. I remember worrying about how I was going to destress because I was like but if I don’t smoke and now don’t drink then where is my stress going to go? Then I realised I wasn’t stressed and I didn’t need either I thought myself into thinking I was stressed. So then I was like oh that’s great I don’t need wine now and I am never going to risk that knife in my head ever again. So then figured right my work is done. Then my body started to reject food. I got all types of terrible pains in my stomach and it took years to figure out what were pain triggers. I discovered over those years I had ulcerative colitis but this condition I control through diet and exercise. But it had taken me years and years of pain to realise and accept gluten is not my friend. I don’t take complex protein like meet and decided no animals but will eat eggs. But no potatoes no fruit no vegetables no potatoes but yes to pickles. I can eat pickled foods without pain. I need sleep as this effects inflammation levels. None of my life choices have been made by my personality without been pushed into finding answers because of pain. I know if I didn’t have pain I would not have been so strict with myself. It has felt that my body has taken over my choices. But I have had so much pain that I don’t feel like I am living inside any limitation or restrictiveness I am just so grateful to live with out pain or very low levels of it and I know now that there is an intelligence in the body because it wants to be functioning well for me I just didn’t know how to listen to it. This relationship is ongoing and I know sleep I should do better too. I do get a problem in my ears if I don’t sleep enough so this I have to be better at but it’s a daily learning and listening thing. I guess our bodies are our temples and we need to respect them as much as possible.

[@LOLA-uw6mr]

Interesting read. Thank you for sharing your experience. I've experienced this as well, just recently with dairy. Gave it up for 30 days, and when I tried to pick it up again, my body rejected it.

[@suzanahas4740]

Great interview, great man..

[@ShoshanaBrand]

It's weird that he takes tests using X-rays and M.R.I. machines, and even brings his sons along, w/out being scared about their radio-active dangers. One can get the same results of an amazing health state, joy, and strong energy with one meal a day and no carbs, in addition to exercise and good sleep. Simple.

[@muzzletov]

for one, what would be the issue with MRI? and second, how can you conclude that no carbs is a good thing? btw, OMAD has no additional benefits to pure caloric restriction, even negative effects in that you lose muscle mass more rapidly. you didnt get just one thing wrong, according to peer-reviewed studies. wish you much of luck going forward, youre going to need it ;-)

[@ugofureogoro1042]

Add the emotional healing ?

[@kwimms]

no carbs? lol... okay then. Do you just eat raw rabbits?

[@thebutterfly3ffect77]

I’d place a sizeable bet that he takes iodine for this

[@robynhope219]

No carbs is not advisable.

[@StMac-qo9jk]

WOW! I’m amazed! I’m a pretty healthy. 76 years old, female-I wish I were younger to be able to be part of this young man’s venture. I’ll continuously follow his blueprint podcasts for as long as I can❤️ He’s such an inspiration 🙏❤️🙏. I wish him all the LUCK in his positive journey for mankind.

[@kathleenvickroy450]

Just curious why you would not follow it? Do you think you are too old?

[@kintsugihabits403]

You should try it now, you could live to 120+

[@plantsfromheavenbotanicala4792]

I respect Bryan for all he has done so far and his contributions, I’m really grateful. However, one day will be his time like there is one for all of us. I do support his idea of being as healthy as you can be specially when you have a family ❤🎉while we get to be in this world

[@janetderouin9533]

Dhru, you are awesome..so respectful of your guests. ❤❤

[@sandybayes]

Bryan is not alone and I too think there is enough evidence to stretch our current lifespan. Hopefully, within the next 10-12 years there will be considerable advancement to create more time on the other end and so on.

[@cynthiahoz3948]

Bryan Johnson is truly a unicorn. The Adam and Eve analogy with respect to personal accountability is profound. As an RN / MBA focused on AI/ ML, the work Bryan and his team are performing to unravel these complex issues is quite intriguing. I will be following him going forward. And compliments to Dhru’s superior interviewing skills.

[@wymandyer6261]

great program,,Bryan is fascinating,,,im 62, not sure id want to adopt the whole program but im always looking for new tips,,thank you

[@rebeccamalicsi4470]

Thank you for sharing these informations

[@dinomiles7999]

I'm so happy we met ...

[@divarose2017]

If I have an empty tummy, I cannot sleep, and I have to get up and eat something , like scrambled eggs, then I can go to sleep;-))

[@lillianB916]

❤ Bryan is totally Awesome!!! WoW, thank you!!!!