Renin-Angiotensin-Aldosterone System (RAA System) | Made easy with a step-by-step explanation!

🩻 Support the channel - / siebertscience
🧠 For all my science videos and resources: www.siebertscience.com​
💻 My youtube channel: / siebertscience​
-----
In this video, explain how the RAA system regulates blood pressure, blood volume, and sodium homeostasis.
0:00 Introduction
0:53 Homeostasis
1:30 Stimuli
2:14 Sensors
4:58 Angiotensin II Synthesis
8:33 Effectors - Aldosterone
11:33 Effectors - All Other Effectors
15:17 - Regulating Glomerular Filtration Rate
16:50 - Recap of RAAS System
19:02 - Review!
19:34 - Endscreen Silliness
🦴 Other videos referenced:
Urinary System: • Urinary System | Struc...
Nephrons - Filtration and Reabsorption Basics: • Nephrons - Filtration ...
Homeostasis: • Homeostasis - BEST Way...
👕 Support Siebert Science and buy Siebert Science merch!
siebertscience.com/store/
-----
Image used:
OpenStax Anatomy and PhysiologyOpenStax, CC BY 4.0
upload.wikimedia.org/wikipedi...
creativecommons.org/licenses/..., via Wikimedia Commons

[@user-pz2fm1bm5n]

This guy actually knows how to teach... Thank you sir

[@tructran-ud3mm]

Thank you , better than lecture 2hrs in class

[@ogagaskitchentwist7477]

Correct!

[@manash8400]

Couldn't agree more 😊

[@andyvlad8592]

Agree

[@huait5492]

agree

[@user-lk4lm3wf1p]

20 minutes of this has saved me hours of studying. Thank you!

[@jennwood9457]

OMG!!!! I only have a few more weeks of Human Anatomy and Physiology II and I am so MAD I just found you!!! You were here when I started Anatomy I and I didn't even know it. You have such a flow and easy way to follow each body system etc., Although I am just so mad I missed you for so long, thank you for being here now at least! THANK YOU!!!!

[@SiebertScience]

Hey Jenn! You're very welcome! Glad you're finding the videos helpful, and good luck with the last few weeks of your A&P class. Also, thanks for the support on Patreon!

[@charlottemupfunya1047]

Impeccable teaching skills. I really liked the concept of dividing the homeostatic process into 4; stimuli, sensors, intergration and effectors

[@sumeranasim9233]

You are the best at teaching. You made things so easy to understand and learn. Thank you.

[@AL-qq8hb]

Excellent video, thank God I know English! By far the best explanation I've heard, you're great. Greetings from Spain, you've probably saved my med school exams :)

[@jennyrios9535]

Love your videos and I especially appreciate how clean and well thought out your diagrams are! Thank you so much for your work.

[@josephb8499]

You’re literally the best teacher ever…. Thank you!!

[@user-mi5cw5zo5i]

I'm so happy that I have found you're videos!! You are making my anatomy and physiology classes much easier to study for!

[@sophiepiggie5175]

Mr Siebert, you are AMAZING!!! I was so confused before watching your video. Now it’s crystal clear!! Thank you soooooo much!!!!!

[@michaelcoates8044]

Great video, your teaching style is so engaging and comprehensive. The labelling exercise at the end is a beautiful touch. Really happy I've found your channel, no doubt they'll be helping me through my Osteopathic degree for the next 4 years!!

[@user-jz2jq8wp8r]

Learning and retention are all about connection to the content. WOW. For whatever reason, your visual outline w/ a concise explanation finally brought it home. Thanks...from the bottom of my kidneys !!

[@ST-gd4eq]

Thank you so much for this video! Your content makes these subjects very easy to understand and also very fun! Makes me enjoy learning these things.

[@minglixo]

i cannot even explain how amazing you are at explaining this. THANK YOU SO MUCHHHHHHHH

[@Savvyjen7]

Thank you so much! You are an awesome teacher! I now understand somthing I've been reading about for a week. Thank you!

[@lobofitness6997]

Your videos have made me understand concepts I have long ago struggled to comprehend. Thank you very much!

[@Kaibutsu16]

Thank you very much. The way you explain things is really interesting and captivating.

[@BiiraAngelic-zf2pw]

u r such a good teacher, thanks for the description

[@claudiasantisteban478]

Such an amazing explanation of the RAAS!!!! Kudos and thank you!

[@josephdivineande8085]

Wow!! Fantastic explanation. I can't still understand why I found this concept difficult back in Medical school. The stuffs keep getting easier. Thanks for the superb explanations

[@RWB_Yoga]

Thank you. This was the best explanation I've seen. Very clear & helpful.

[@maisa510]

Your explanations are top tier!! Just what I needed before an exam. Thank you!!!

[@illatease]

Thank you so so much for drawing ALL the visuals 🫢AND explaining. They are very helpful!

[@ticathegreat6799]

This explanation iss the best that I have come across so far. Thank you so much!

[@user-cp2bo9xi2r]

You make it so easy to understand the whole process of RAAS. Thanks a lot!!

[@SiebertScience]

You're so welcome!

[@mhaulg]

Thank you for explaining it really well and for easier to understand you’re a really helpful to us students.❤

[@daniel_musiclogue]

Fabulous explanation! I loved all contents in your video, well explained for us to understand easily! Thank you for making such a good video :)

[@Iliona25]

Never understood better! Thanks a lot!!❤

[@HomaShahnawaz]

Thank you so much. Great help Sir. It is people like you that makes the world a tolerable place to live,

[@annmarieraque3302]

Such a good video! Love your diagrams

[@HeartmindUK]

Wonderful video and thank you for producing.

[@ladycdp4u]

Thank you very much! This video explanation is extremely helpful.

[@OrvilleTaylor-kk4fe]

I love your lectures.

[@glamboxbeautylounge]

Whoaaaaa you are the best. You teach better than my Prof

[@user-dc9xj9kz2g]

Thank you soo much this is such an amazing resource and you're such a great teacher!!!

[@paddyc93]

This review was excellent.

[@user-od5cj6ds3f]

You ARE THE MANN!!!!! I finally understand RAAS. Thank you :)

[@32clairem]

The way you explain this is amazing, thanks 🎉

[@SiebertScience]

You're very welcome!

[@tinamusabula3970]

Wow this is good, well expanded

[@mrsrestorationoftruthyahsc3057]

Never understood this until NOW, Thank u so much❤

[@avhossari7219]

Man, you are amazing.

[@tranminh5396]

This lecture is very lively and interesting compared to this in school. Thank you so much

[@nancybarbour7710]

Amazing! I have hyperaldosteronism and this gave me a deeper understanding. Wish you were my dr.!!

[@mikaelad8751]

Thank you sooooo much 🥹

[@marthaschurr7827]

wow great video and ur graphics are so beautiful, thank you

[@Christinabekind]

You have a gift of explaining things 😍🤗😊 ty

[@yuxianglin1076]

The best one out there

[@RaheelHassan-hp5mo]

Very helpful!!!!

[@kaminski1ayla]

Thank you so much! you are an A&P SAINT!

[@drkavithapurushotaman6552]

Excellent video. Thank you so much!

[@SiebertScience]

You're welcome!

[@sajiruddinsk8129]

Excellent!

[@timothygenaw2199]

Very good diagram. Thank you

[@Akirathetiger]

You taught this better than my prof!!

[@devanshusharma3243]

Amazing. Thanks.

[@huait5492]

thank you so much

[@shinn-tyanwu4155]

Great thanks 😊

[@mollycavazos32]

YOU DID AN AMAZONG JOB. I UNDERSTAND IT ALOT MORE THANK YOU

[@SiebertScience]

Glad it helped!

[@NatashaKalaluka-zb1nw]

Job well done you are the best😊

[@masud_studies]

Outstanding.

[@elianal.8801]

THANK YOU SO MUCH!!!!!!!!!!!!

[@cristy7394]

I have been self-studying my A&P II course based on just the textbook and my professor’s ppt slides because the lecture weren’t helpful. If you were to be my professor, my A&P II course would be so much better and easier to learn, especially for someone like me who is a visual learner. These picture illustrations and side by side explanations are amazing!

[@abdirahman2101]

thank u very much i understand very well

[@leena3330]

ur the best 🙏

[@lucsonbrendle6567]

thank you

[@ayannalynn8902]

Great video :)

[@Jaydanaya]

Thank You🙏🙏🙏

[@HassanFatimah-pv5xf]

Thank you ❤

[@MrPatrickczk]

Best one ever thank uou

[@karolinapamedityte7198]

I like your video’s, simple and easy to understand. Can you do lymphatic system?

[@SiebertScience]

Thanks! I'll add lymphatic system to my list of videos to make!

[@cartermember21]

Keep making more videos 😊

[@roj-nc2iq]

PERFECT

[@louikaradsheh529]

Bril lecture. Angiotensin II has an effect on both afferent and efferent arteriole but it mainly constricts the efferent to maintain the GFR.

[@hyphaeahpyh]

i’m just learning this in class! thank you!

[@SiebertScience]

Awesome! You're welcome! I'm just curious, what level of class is it for? (high school, undergrad, med school, other?)

[@hyphaeahpyh]

@@SiebertScience undergrad

[@deborahmoses4836]

You naturally intelligent sir , you make physiology of the kidney to me to very simple. Easy to understand. Thks

[@chrislane2322]

3 seconds into the video: "He has a really good presenting voice"

[@nikkibel.viewer]

THANK YOUUU

[@asantewaa._gmail.]

God bless you 🙏☺️

[@dr.raheesazad6972]

Thanks God bless you ❤️

[@SiebertScience]

You're welcome!

[@user-cu2wm6ep7b]

Thank you for your great video. Making a very difficult concept so easy. I checked the first aid, aldosterone only affects the ENAC and NA.K PUMP in collecting tubules not DCT .is it correct?

[@paulatewakatama8067]

Hello sir Siebert could you please cover Pharmacology 🙏

[@rameenfayyaz966]

Thank you!!- quick question, since you mention that this system is about low levels of Na+ if there was a high intake of sodium by the human, like eating salty meals- would this system cease? as in stop the stimulation of aldosterone to prevent reabsorption of Na+ into the blood stream and allow it for secrection into the urinary system.

[@dankbudwoi871]

Does rehydration stabilise, reverse the activation of the ras system? I got really dehydrated few years back and have had high blood pressure ever since and Insomnia, palpitations...

[@MiViLiX]

May Allah bless u and ur family fr

[@sarinakhan6946]

The macula densa are in the DCT? I thought the DCT was on the other side of the Loop of Henle?

[@pallavpandove3179]

Hey Siebert could u please make a video on genes and how they carry forward to offspring . Btw love the way u teach

[@SiebertScience]

Thanks! I'll add genes and reproduction to my "videos to make" list.

[@pallavpandove3179]

@@SiebertScience I really appreciate it I WILL BE WAITING FOR IT

[@Abdullah-rs9mz]

beast

[@SumayaAbdidahir]

I’ve almost fallen asleep on the video 😂❤it was soo clear, concise, and simple to understand, it doesn’t seem difficult anymore. Just wooow. Thank you for making these videos. ❤❤

[@luciaashipala901]

You make it so much easier than how private institutions teach us (😂❤) if only the was a nursing school where I can gt my degree online 😅

[@lucywilliams1634]

Question: could this system explain why someone with renal agenesis would have POTS?

[@globalcitizen7]

Who regulate the macula densa and juxtraglomerular cess . I mean who makes them act???😢

[@dr.chris8]

Struggling to say Juxtaglomerular had me laughing 😂😂😂

[@schamgardilungani-dilu4430]

KUL needs you buddy

[@SiebertScience]

What is KUL?

[@schamgardilungani-dilu4430]

@@SiebertScience The name of my university. Catholic university of Leuven in Belgium

[@francesmayson9573]

❤

[@josephdivineande8085]

Renin is an enzyme. Because it cstalyses the degredation of an hormone called angiotensinogen to angiotensine I, it is called Enzymatic hormone.

[@QueenieBorlagdan]

add to heart sakin

[@iGlimmyr]

Hmm I went looking for this topic because my blood pressure is too high, not too low. My renin levels are twice the normal level.

[@juliaevanusa6631]

renin is an enzyme? my professor is calling it a hormone and my textbook is calling it an enzymatic hormone I'm so confused 😩

[@SiebertScience]

When renin converts angiotensinogen to angiotensin I, it's acting as an enzyme, not a hormone. Hormones bind with receptors on cells, whereas enzymes facilitate a chemical reaction, and the conversion of angiotensinogen to angiotensin I is a chemical reaction. I think there are some renin receptors on some cells, which would technically make it a hormone as well, but that (renin binding to cell receptors) is beyond my expertise.

[@juliaevanusa6631]

@@SiebertScience ahhh okay!! amazing! I just want to let you know your videos help me so much! You explain things so well and I am such a visual learner so they are like a lightbulb for me 😁

[@SiebertScience]

@@juliaevanusa6631 ah yay! Glad you’ve found them helpful!

[@tasya7508]

Nowadays Sodium deficiency is a myth

[@gina4168]

Good explanation but why so many cuts on the video. Too much information too fast. It's not tik tok here.

[@SiebertScience]

For one, I'm not reading from a script, so I'm often unhappy with the way I say something at first, so I say it again differently and cut out the original. That leads to a lot of cuts. Second, I just don't like long (or even short) pauses or hearing my breath. So I often cut those out. Mostly this is a stylistic choice, I guess. And I like that it shortens the video a bit. Third, I don't really know. There's no way to make a video that works perfect for everyone. So I try to make videos I like, and I kind of like doing it that way.