nuclear import and export

[@a.s.2820]

THANK YOU this explains it so well!! I have much to memorize for my exams and I've been feeling really dumb lately because I could not for the life of me understand the steps, but these visuals along with the simple description was AMAZING. I actually get it now. Thank you so much to whoever made this, truly.

[@satyajitchowdhury3350]

This one is actually good. After reading Bruce Alberts and then watching this made me crystal clear about the role of Ran.

[@krithikakeethu2458]

could you just say me the page of bruce alberts pls

[@dafnefreitas2443]

@@krithikakeethu2458 in the edition number 6, this subject matter it's starting on the page number 649

[@aparnasingh7]

is bruce alberts better than cooper? ( a genuine question)

[@satyajitchowdhury3350]

@@aparnasingh7 IMO Alberts is better than cooper.

[@anuragnath8182]

​@@satyajitchowdhury3350 what about gerald karp?

[@emberlite]

This video is perfect!

[@lkjklkjlkjkl2902]

I would like to import you into my nucleus.

[@krishnendumondal5150]

Awesome love this piece of work. I want more videos like this. Animation is good. Easy to understand. Thanks.

[@kamij2869]

I came here after my lecturer confused the hell outta me on this - honestly, I've never been more glad! This video nicely explain everything with simple animations!! Thanks xx

[@pujas390]

Helped me a lot .. very good explanation 👏 Thank you so much..

[@davidgiunashvili4397]

the best video of nuclear import and export

[@Mina1Isabella2Marie]

An excellent video! Thank you very much, it helped a lot!

[@aparnasingh7]

thanks !! it helped me clear up my concept... the last part was messy at the beginning after watching this video i was able to understand!!

[@ecepehlivan1710]

Amazing work, thank you so much!

[@carolinavares4318]

Thank you for saving my grade, this is amazing

[@dr.dinmuhammadbuzdar2478]

Best explanation 👍

[@judyalrekabi7971]

thank you 정말 this video helped me to understand this idea in the Biology Cell

[@sovagogabor8240]

Very simple and helpful video

[@doussadoussa2025]

This helps me a lot thank you so much

[@kevinderry15]

spot on! that was absolutely what i'm looking for

[@kushagarjuneja9996]

You saved me, mind-blowing!!

[@ninadoomen2125]

I found this video right after I listened to my own teacher for 35 minutes explaining the same thing. this is way clearer thanks!

[@ihaveadreamtoachieve3824]

Flawless 👌🏻

[@Nonbisi248]

Thank uu !! you're a life-saver

[@gautamspeax]

Great vid, thinking there are trillions of such processes per microsecond in one human body, then thinking how complex it all is at quantum level O_O

[@KajalSharma-ff2vz]

Thank you very much for this video ❤

[@BruinChang]

Thank you for this instructive and helpful presentation! I am still struggling to memorize the flow chart due to too many roles and two compartments.

[@KENNETHUDUT]

wtf this blew me away thank you

[@hanch96]

Very clear and helpful thank you

[@sakshirai8128]

Just perfect which i was looking for.

[@sunflouwerry]

Jst amazing thanks a lot 🙌🏻

[@vivianaorosco7383]

Alaaa, me sirveee c: thank u so much!

[@rishabplays2389]

Best video on this topic

[@abasboulariah359]

A perfect vedeo❤️❤️💜

[@MarieLFC]

Perfection 👌🏾👌🏾

[@alexandru6747]

Excellent!

[@sarakatoo4760]

U r amazing!!

[@kikibear12146]

PERFECT EXPLAINATION!!!, ur a livfe saver!!! :))))))

[@chaoukiyahyati8171]

very clear video. i have only one question remaining. why does the importine with the cargo spontanouosly go to the nucleus?

[@johnx5k]

Wow 🙏

[@marianaa7384]

thank you so much!

[@tapaspanda8787]

Awesome classes

[@ahmetetkamuhziroglu7206]

omg it is awsome ...

[@DoctorN200]

Great 🤍🥀

[@408-gulafshantarannum7]

Best video so far.

[@Loizxn]

Спасибо, понятно даже мне

[@oxjohn3334]

Awesome

[@ullasrajs3537]

Cool nice

[@HomeAtLast501]

I know that proteins are produced by the ribosomes, and that the ribosomes reside in the cytoplasm, not within the nucleus. So I can imagine that a protein that has been produced by the ribosome, but that belongs in the nucleus, would have to be transported INTO the nucleus. What I'm not clear on what kind of protein would have to be transported out of the nucleus. I imagine that any protein in the nucleus is supposed to stay there, since all proteins are produced in the cytoplasm and wouldn't be moved to the nucleus unless needed there.

[@africansubscriber4530]

Thank you

[@teodoralapadat5857]

amazing

[@WoLFGAMING-yz7wo]

bro really helped me

[@randa4549]

Thank you guys ❤️❤️❤️

[@QAJC]

very nice video, but it could have been better with the precision between importin alpha and beta

[@mohamednejikhalfallah1295]

can an import and an export take place in the same nuclear pore complexe ?

[@marianadeau8632]

That one dude who disliked this was probably just too dumb to understand it

[@conyrch1922]

i didn't dislike but i'm the dude who is too dumb to understand XDD

[@dontrunnaway5741]

THANK YOU

[@ahmadha5069]

Thank you❤️

[@omkarlande8413]

Thanks a lot ....

[@lcl1129]

I only perfectly understand now but at end she had hurried to non discuss which molecule carry back Exportin.

[@lealemeur5765]

you just save my life thank you

[@abdullah_224T]

Thanks you

[@ViniciusLima-ie7ze]

Foda

[@diogenesdiaz649]

I need this video in Spanish 😩

[@ant2984]

incroyable

[@maher0001]

يلي جاي من rbcs يطج لايك 😂😂😂

[@aleensy9670]

🖒🖒🖒😂😂😂😂😂

[@maher0001]

الله و البيو 😂😂😂😂

[@sabeentoss1651]

😂😂😂😂😂

[@hamzah1183]

لساتنا بلفصل الرابع😂😂😂😂

[@maher0001]

الفصل الرابع اعادة يا نس 😂😂😂

[@MehmetFatihKaya63]

ANKARA TIP’LILARA SELAM OLSUN 🙂👋🏻

[@codespher3128]

Assuming NTF2 has interactions with NPC proteins that allows it to slide into only nucleus side and bring RanGDP back. Then another protein is supposed to bring NTF2 back that is only able to pass to cytoplasm side. And another protein is gonna have bring that protein back to nucleus and so on. Where does this loop end? lol

[@vaidehirathod8727]

NTF2 binds RanGDP in the cytoplasm and then ferries it into the nucleus by virtue of the fact that NTF2 can also bind FG repeats on nucleoporins similarly to NTRs (Bayliss et al., 1999). NTF2 has a much lower affinity for RanGTP than RanGDP, and thus travels empty back to the cytoplasm after its cargo (RanGDP) is converted to RanGTP by RCC1 inside the nucleus triggering its release.

[@codespher3128]

​ @vaidehi rathod I was studying for a lecture when I was watching this video. I graduated recently. I am so quick to forget everything I learned. I have no idea whats going on in this video. I forgot what a protein even is hahahah. Thanks anyway

[@dilekduzgun6066]

You saved my life guys :)

[@lucascharrier1740]

doesn't RAN-GDP bind Bêta-importin BEFORE the importation and is then exchanged in the nucleus by GEF ? I'm confused now

[@GeomaniaDasher]

so what happens to the NTF2? wouldn't it build up in the nucleus this way? or is it exported back out through RanGTP

[@vaidehirathod8727]

NTF2 binds RanGDP in the cytoplasm and then ferries it into the nucleus by virtue of the fact that NTF2 can also bind FG repeats on nucleoporins similarly to NTRs (Bayliss et al., 1999). NTF2 has a much lower affinity for RanGTP than RanGDP, and thus travels empty back to the cytoplasm after its cargo (RanGDP) is converted to RanGTP by RCC1 inside the nucleus triggering its release.

[@doloresmeneses55]

Do IDPs binds to the importin?

[@auraeaurorum1177]

Noch irgendjemand von der Wiedemann Vorlesung hier?😂

[@KIRUBAKAR]

What happens to NTF2?

[@rayanbendz1361]

Bro!!! After this,there is absolutely a god one and only ❤️

[@JacindaRivera]

2:48

[@ahmad-md9dh]

RBCs

[@zainaljerrde2885]

حدا جاي من نوطة RBC 's?

[@bayanna1367]

I don't understand in inglish I hope translate this video in Arabic

[@DouglasSantos-cp3dm]

I wanna kiss this video... with tongue!! thank you!

[@abdullah_224T]

Thank you