Classification of Sensory receptors | Sensory Physiology mbbs 1st year lecture | CNS physiology

Physiology lecture on central nervous system physiology explains Sensory receptors
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Afferent neurons have sensory receptors at their peripheral endings. Receptors as the term indicates receive information or we can say characteristics of a stimulus from the surroundings. The stimuli are of various types depending on the type of energy change for e.g. there can be either mechanical stimulus , chemical stimulus or thermal stimulus etc. Body has sensory receptors for detecting different types of energies. But once the receptors detect the stimulus, it has to be transmitted to the CNS as action potential, so receptors convert the stimulus energy into electrical signals. This is known as signal transduction.
Sensory Receptors can be classified in 3 ways
1. based on their location: exteroceptors, interoceptors and proprioceptors
2. based on modality of stimulus they detect: mechanoreceptors, chemoreceptors, thermoreceptors, nociceptors, and electromagnetic receptors .
3. Based on rate of adaptation: Slowly adapting receptors and fast adapting receptors
In skin , their are various mechanoreceptors. However, they are located in various layers of skin e.g. Merke;'s disks are located superficially in dermis and detect superficial texture of the object while Ruffini ending is deeper in dermis and detects pressure. Also there are Meissner’s corpuscle versus pacinian corpuscles. Both these receptors adapt very fast. Thus, they detect vibration sense. But, meissner’s corpuscle respond to slow vibration while pacinican corpuscle respond to fast vibration because pacinian corpuscle adapt very very fast. And pacinican corpuscles are located deep so they respond to deep pressure vibration while Meissner’s has to be superficial like a flutter on the skin. Also, meissner’s corpuscles detect the sensation from a small superficial area while Pacinian corpuscle respond to a stimulus even when it is present in a little larger area. This is known as receptive field of the receptor.
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Thank you so much for having this topic! It was helpful...

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[@SAURAVKUMAR-qj3lm]

Mam your vedio is awesome please upload full cns vedio mam

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Playlist on sensory system: m.kzbin.info/aero/PLnt1wzLU3qo3m74f5LF02-vzia_rm3IbG

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Mam special senses and motor

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Coming soon

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5:30 - adaption of receptors

[@art_maniac_sudheer3586]

Mam what is the direction of AP conduction in Free nerve ending receptors ? from axon to cyton ??

[@PhysiologyOpen]

It’s bipolar neuron....so basically the axon coming towards skin...actually carries AP to the spinal cord

[@aaqil8344]

Ma'am, nociceptors detect stimuli whose intensities may cause damage to neighboring cells. Do the stimuli damage the nociceptors too? When cells are subjected to such stimuli they either adapt or get injured. After cellular adaptation, does the nociceptor still detect the once stressful stimulus?

[@PhysiologyOpen]

If the damage is deep enough, yes the nociceptors will be damaged..like happens in burns...superficial burns are very painful because in them nociceptors are stimulated and cause extensive pain..however in deep burns nociceptors are themselves damaged..so they are not painful...pain starts when healing occurs.. When cells of skin adapt i.e to chronic painful stimuli, ofcourse they are becoming keratinized or due to frequent injury fibrosis occurs...in both cases they become less responsive to the same stimulus for which they were responsive before i.e the threshold of stimulus increases

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[@PhysiologyOpen]

Why it is different may have 2 answers - one by how genome works - Receptor binding domain differs in various coronaviruses, coz their genomes are different leading to different amjno acid sequences in thebinding domain. 2nd may have be a teleological answer - that is the evolution worked like that, and all of the various variations of the receptor binding domain led to survival of the virus

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What is sensory coding ?????

[@PhysiologyOpen]

Check out 3 videos in this playlist: sensory transduction, labelled line principle and receptive field for sensory coding : m.kzbin.info/aero/PLnt1wzLU3qo3m74f5LF02-vzia_rm3IbG

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Guyton according to me.

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