PI3k/AKT/mTOR Pathway

[@selimrozyev5637]

Thanks author for the video. One thing to add - PDK1 phosphorylates Akt protein at Threonine (T308) residue not Tyrosine (Y).

[@rajeshbhardwaj298]

Excellent video, please note than PI3K can also be activated directly by receptor tyrosine kinase without involving Ras-GTP.

[@piano_master_5246]

Very good video. You Indian guys are the best when explaining molecular stuff, almost all the stuff I understood via KZbin was explained by Indian youtubers. People explaining the stuff in American English somehow don't have the skill to explain stuff properly, don't know why.

[@hussainbiology]

thanks for appreciation..Glad u like my stuff

[@evamadaan4933]

I was confused in this topic and here you are with the video thank you so much👏🌟

[@hussainbiology]

thanks for appreciation..Glad to know that it helps ✌️

[@hopeful3456]

Insulin receptors exist as diners and when ligands binds two diners bind to each other to form tetramer

[@pritipandey112]

वेटिंग फॉर this वीडियो

[@haiderinam1524]

thanks for the video, one thing i would change is that I would call tyrosine 308 on PKB Y306, not T308

[@sudharmabanerjee6699]

It should be Threonine (Thr or T), not Tyrosine. He was confused while explaining.

[@rabnawazkhan4312]

Goood.....waiting

[@hussainbiology]

✌️✌️

[@ashishanand1163]

Your videos are simply awesome.....Please try to make more Dev. Bio . videos as CSIR NET exam is on the verge. thank you.

[@hussainbiology]

thanks Ashish for appreciation. Glad you like it...

[@rakshithm1257]

1:29 does insulin bind RTK or insulin growth factor?

[@guptashivam6399]

Insulin as a ligand bind to rtk receptor

[@sudharmabanerjee6699]

Good work. Need to correct few info.

[@hussainbiology]

thanks... yes please

[@muhammadsulaiman6023]

Sir can you please tell me about the best book for such pathways????

[@hussainbiology]

Lodish Cell Biology , Alberts Cell Biology

[@noycrf5158]

أريد شرح بالعربي بالنسبه لموضوع PI3K-AKT

[@alkhader2school450]

RTk form dimers upon engagement with there ligand but the only exception lignad is insulin ?? did iam right ?

[@ikrambenali9452]

Yes

[@the_encephalonaire]

Sir, please tell me that can i do MSc in genetic engineering after my Bsc in microbiology ? Or what else is required to pursue MSc in genetic engineering?

[@krishnendukundu6446]

For msc biotech....u will get broad range..in industry as well as research

[@likhithabb8899]

We cant write this for pi3 pathway

[@sheikhiqbal715]

Sir ,r u also available on telegram

[@hussainbiology]

No dear...

[@hussainbiology]

Available now

[@evamadaan4933]

@@hussainbiology @hussainbiology is this the channel

[@hussainbiology]

@@evamadaan4933 i am new to Telegram.. What i know is my id only.. and yes as Hussainbiology 1253420376

[@hussainbiology]

@@evamadaan4933 Yes Eva

[@bussymed7912]

Thank you so much. #bussymed

[@hussainbiology]

You are welcome

[@christofferrasmussen6325]

Sorry i'm late. I am pretty certain that PDK2 does not phosphorylate S473, and that is instead mTORC2. Furthermore, you never care to explain how PDK1 and 2 are activated by PIP3

[@kennethdaniella-ab7963]

yep he did not explain it but you can read it at ncbi website, there is a ton of research paper there related to this

[@cosmicvlog8196]

Aree kehna kya chahte ho bhaiii 🙄 pura ghuma diya hindi me hi bol le

[@hussainbiology]

Hindi mai samajna hai to ye dekho kzbin.info/www/bejne/hnzYeJmsnpdqmpY