PROTEIN STRUCTURE- Amino acid structures. Primary, secondary, tertiary and quaternary proteins

[@sabriya1225]

please make chemistry as easy as bio because i love how you explain so easily

[@MissEstruchBiology]

haha. MaChemGuy is good! Or AlleryChemistry

[@berinyilmaz8850]

u are one of the best teachers on youtube miss estruch, you made every difficult topic clear on a level biology

[@MissEstruchBiology]

awww you're too kind 😊

[@anjalibhandari3851]

Thank you so much Miss Estruch, your videos are detailed and easy to digest.

[@MissEstruchBiology]

I'm so glad you find them easy to follow and helpful 😊😊😊

[@anasmohamed7110]

Can’t tell if this is a pun or not 😂

[@anjalibhandari3851]

@@anasmohamed7110 lollll it wasn't meant to be. I just realised.

[@thelighthouseunderthestars6209]

I'm doing an MSc in nutrition and this was really helpful in refreshing my memory! Thank you

[@MissEstruchBiology]

You're so welcome 😊 Pleased it has helped!

[@kashmalaasghari953]

I'm so grateful for your videos ❤if it weren't for you I would be failing biology (I have a test tomorrow!)

[@MissEstruchBiology]

eeek good luck!!!!

[@ivygracelane]

u have saved my life thank u queen

[@MissEstruchBiology]

You're so welcome!

[@Rain-gg8vd]

Thank you so much. I was having trouble understanding how the different levels of protein structures related to each other.

[@MissEstruchBiology]

You're so welcome 😊 Happy to hear it helped

[@samsephton5788]

Your videos are so great. Thank you!

[@MissEstruchBiology]

awww thank you 😊 Hope they help I give extra advice and quizzes on my Instagram too!

[@StunnerMW]

At 10:15 does it matter if the active site of the enzyme is changed because we know of the induced fit hypothesis and the active site being changed will have no effect

[@alexslaven3071]

Great video , do we need to know about ionic bonds as well as disulpide and hydrogen bonds?

[@VictoriaOyefusi]

Good thing i found your channel in year 12!

[@MissEstruchBiology]

I hope it helps!

[@cocomuffin4666]

this was so incredibly helpful and succinct - thank you miss estruch ! !

[@Rawdah_Alaan]

anya pfp hehe

[@cocomuffin4666]

@@Rawdah_Alaan indeed (i am a telepath)

[@Noel_Jaco8]

You’re a real one 🎉

[@alicemidori8087]

hello, at 7:01 where it says the tertiary structure is held together by ionic, hydrogen and disulfide bonds, are you referring to the hydrogen bonds that are formed in the secondary structure? Also, why is disulphide spelled in 2 different ways (disulfide and disulphide)?

[@malikaturla]

Disulfide and disulphide are both correct. One is the American version and the other British.

[@jasonsingh9698]

Hi Miss, do we need to know about globular proteins and fibrous proteins for aqa ?

[@jhcrep3178]

Thank you so much! You teach in a way that sticks

[@zaidyacoub5406]

You are actually amazing

[@MissEstruchBiology]

Thank you, that's so kind! Really hope all the videos are helping you with your Biology.

[@faysalmohammed2821]

Hi miss estruch, nice videos, I have been using for the past few weeks recommended by a fellow pal who ain’t wrong on how you really go through the aqa a level bio which I really appreciate. My plan was and still is to watch ur vids, make notes on the vid, condense it multiple times as I have some something with the notes and then do a blurt method of writing everything I remember from that subtopic. E.g with carbohydrates write everything Ik and if I forgotten something I’ll add it in green ink. Moreover My enquiry was on this video of proteins on how you have went through it but didn’t mention fibrous nor globular proteins and all the examples. Do we need to know this or is you’re information for teaching good enough to use then revise with do then do practise exam questions and still get good grades. As I feel I have missed out something which may effect my grade in the subtopic proteins. This may happen with other subtopics however I just wanted to know with how you have taught each subtopic with what you need to know is enough for the exams? Thank you faysal

[@MissEstruchBiology]

Hello, So glad the videos are helping you and your revision technique sounds good with the blurting. Fibrous and globular proteins are not on the AQA specification, nor do you need to know lots of examples. This video covers all the content on the theory for proteins in the Topic 1 Biological Molecules part of the specification that you could be assessed on. Hope that helps.

[@notme-tf8sq]

Hey Miss! there's something that's really confusing me about this topic it isn't really a part of the lesson but in later lessons about enzymes, it's said that they are in tertiary structure, so do proteins stop at a certain structure or level? they don't have to complete all four stages?

[@MissEstruchBiology]

Hello Both the tertiary and quaternary are final 3D structural stages for a protein. The only difference is that a quaternary structure has more than 1 polypeptide chain folded into the final 3D shape. Hope that helps

[@notme-tf8sq]

@@MissEstruchBiology that makes alot of sense thank you a bunch!

[@adityamuthyala3253]

Hi Miss Estruch, The spec say "Students should be able to relate the structure of proteins to properties of proteins named throughout the specification." Which proteins/ type of proteins does this mean? Thanks

[@MissEstruchBiology]

This is a lot of proteins! have a look through the specification and note down all proteins mentioned. It includes all mentioned enzymes, antibodies, antigens, membrane proteins, muscle proteins etc.

[@Ftblshorts100]

Do you have any videos on globular and fibrous proteins? Thank you

[@MissEstruchBiology]

in the ocr topic 2 video

[@ImranAwan-n9s]

Fpr the tip given when describing the primary structure, if a question therefore asked to describe the primary structure, would you just recite the definition in the top box, despite it not including the word sequence?

[@marthasmith9720]

Does the quaternary structure contain the same bonds as the tertiary structure?

[@MissEstruchBiology]

hello, yes it does 😊

[@imisiee]

I’ve seen somewhere talk about amide bond and the explanations seem similar to peptide bond when forming a polypeptide chain of amino acids, but what’s the difference?

[@lakavimanasasuthan3719]

Hi Miss Estruch, What is the role of hydrogen bonds, ionic bonds and disulfide bridges in the structure of proteins? Thank you

[@MissEstruchBiology]

The position of the bond, which is determined by the amino acid sequence, determines how the protein folds. Therefore, the position of the bonds determines the final 3d shape (tertiary structure) and thus the function of the protein.

[@ImranAwan-n9s]

Do we need to know more detail about the different types of bonds formed, or just the amount in the video?

[@ayeshashafique6385]

Hi miss Estruch, your videos are very helpful. i wanted to ask if you have done a video on the enzymes topic because i cant seem to find one. thank you

[@MissEstruchBiology]

Thank you, and I am glad to see they are helping you. I haven't go any enzymes series of videos yet, and it may be a whole I'm afraid. I am working on topic 7/5/8 at the moment to correlate with the needs of most Y12 students during lock down. Once I catch up on this I will review the missing gaps in the early Y12 topics.

[@Modest480]

Thanks 🙏 so much ❤

[@MissEstruchBiology]

You're welcome 😊

[@jasonsingh9698]

Hi Miss, do we have to know about different types of proteins. Like enzymes, white blood cells, carrier proteins in the cell surfaced membrane and muscle/ bone proteins

[@MissEstruchBiology]

you till do across the later topics, but not directly within the proteins topic in biological molecules.

[@newstudent1411]

hello miss miss i have a question in soluble proteins the hydrophilic r group are on the outside of the protein and the hydrophobic r groups are in the center of protein. what is the arrangement of r groups in an insoluble protein?

[@shahdmaki761]

opposite

[@5seizures603]

Do we have to learn in detail about ionic,hydrogen and disulfide bonds

[@MissEstruchBiology]

You need to know which part of the amino acid they form between, that the amino acid sequence determines the location of the bonds and that the bonds hold the unique 3D shape of the tertiary structure in place. Hope that helps

[@abia321]

Do we need to know about globular proteins for AQA?

[@MissEstruchBiology]

hey, no you don't for aqa

[@KetaAlevel]

2:03

[@louisexxxxasasasa2567]

Hi, for AQA do we need to know about fibrous and globular proteins? Thanks

[@MissEstruchBiology]

hey , no you don't 😊

[@jasonsingh9698]

@@MissEstruchBiology oh our teacher taught us it

[@MukasineMonique]

Ndabemera

[@Lsy5]

HELLO GUYS

[@MissEstruchBiology]

👋🏻

[@haabeel7702]

cheers

[@huskythegreat3100]

Good explanation, but your British accent is getting on the way. Too many unnecessary sounds. It's quite annoying.

[@MissEstruchBiology]

Glad you found the explanations helpful Can't do a lot about my British accent ☕🇬🇷 I definitely recommend you don't listen to my podcast then 😆

[@huskythegreat3100]

@@MissEstruchBiology I was just joking. Your videos and the explanations of difficult concepts therein are great and of immense help. I did great on my exams, thanks to you!

[@MissEstruchBiology]

@@huskythegreat3100 So glad they helped you! I'm also using a new microphone now to hopefully stop the clicking sound of the mouse being audible.