How a Single Event Can REWIRE the BRAIN: The Neuroscientific Journey from Trauma to Depression

[@drgauravuppal]

Excellent sir . Finally a documentary by a world renowned psychiatrist .

[@PsychiatrySimplified]

Thanks for your feedback. 🙏🏼

[@amitabh15]

How does one treat this post traumatic depression and hopelessness? What tools do we have for someone with the depression/hopelessness and chronic and also intolerance to SSRI and dopamine agonists. I was one of the ones who wasn’t able to escape this phenomenon.

[@PsychiatrySimplified]

Please have a listen to the videos on melancholic depression and the mixed features video.

[@ayeshanabeel2095]

omg!what a beautiful detailed informative video by a most learned psychiatrist i have ever seen..hats off

[@PsychiatrySimplified]

Thank you for your feedback. 🙏🏼

[@klbkatklb]

fr

[@dxxdmxn1010]

this deserves more than 1k views

[@PsychiatrySimplified]

Thank you. We hope we can get there (:

[@cihatobuz8860]

Very good fine details. Very useful information. Thanks. 02.02.2024

[@PsychiatrySimplified]

Glad it was helpful!

[@pigeonarmstrong]

Amazing explanation. Thanks a lot!

[@PsychiatrySimplified]

Thank you 🙏🏻

[@ottife]

Amazing video. Thanks a lot!

[@PsychiatrySimplified]

Thanks for your feedback 🙏🏻

[@honiyadakpe6444]

very informative video. Content, editing and presentation was on point. Keep going 😊😊

[@PsychiatrySimplified]

Thank you 🙏🏼

[@DuduMen-kx7ns]

First of all i would say informative and well represented documentary. Second, I want to ask 1.How does a person overcome childhood trauma who is already in learned helplesness stage? 2.How to get back to normal after their is excessive activation of amygdala and frontal cortex as mention in documentary and balance Neurotransmitter like dopamine, noradrenaline and serotonin?

[@scarred10]

You would need e evidence based trauma treatment comprising psy hoeducatio,emotional regulation training and trauma processing followed by integration into daily life,the therapy may correct the neurobiology like it does in depression.Medication may help with Sx control too.

[@PsychiatrySimplified]

Well said. It's a multi-pronged approach based on the individual pehneomenology ( symptoms) , and then using the range of tools medication, therapy, social interventions etc to move the person towards a reward conductive state.

[@PsychiatrySimplified]

Thank you for your feedback as scarred10 said - it's summarised well - it's a formulation and then application of the tools in the right manner - to help the person move from a reward deficit towards a reward conducive state. The hope circuit can be modulated by medication, psychotherapy, social interactions etc.

[@scarred10]

@@PsychiatrySimplified thanks,Im a physician assistant in psychiatry who overcame severe childhood trauma myself and saw others who did the same during several residential treatment attempts,a very difficult and meandering journey

[@AndrogenReceptor01]

Dr. Sanil, can you do a video on depersonalization/derealization disorder?

[@PsychiatrySimplified]

I'll put in on the list.

[@Desi-Rose]

Yes, please!

[@emresaglam1182]

Thank you very much for your video Doctor Sanil. I watched in amazement, it was related to the things I had. What do you think about the effect of low dose amisulpride increasing dopamine transmission in the limbic system? I've been using it for a while and my symptoms have decreased. Thank you very much again.

[@PsychiatrySimplified]

Thank you for your feedback. Yes amisulpride low dose is known to Modulate D3 receptors situated In limbic system and prefrontal cortex. Glad you found it beneficial. Here is an article - psychscenehub.com/psychinsights/amisulpride-psychopharmacology/

[@emresaglam1182]

@@PsychiatrySimplified thank you🙏🏻

[@sweetyghij288]

Hi sir, My mom has been diagnosed with schizophrenia and she has been prescribed to takeolanzapine 10mg and she also diagnosed with atrophy But she is not interested in taking meds and she is also having so many side effects like muscle cramps and constipation and she has been taking thyronorm 50 for her thyroid Can she take Lions mane supplements? If so can yoou tell the dosage Looking forward to get ur response?

[@PsychiatrySimplified]

Sorry we can’t provide advice like this as that would be irresponsible. Please have a discussion with the medical professional . Wish your mother well.

[@CHITUM1111]

Good 👍

[@PsychiatrySimplified]

Thank you

[@neio4201]

@ 2:30 So How can 1/3 of the dogs have learnt to escape from the "inescable box" when its inescapable? Doesnt make sense.

[@PsychiatrySimplified]

Two stages - Hammocks and electric shocks. Second stage - box with knee high barrier. The inescapable group was classified as the ones initially in hammocks. When they received shocks. Then this group when moves to box were classified as inescapable. They were able to escape. It's the label inescapable in the previous stage

[@neio4201]

@@PsychiatrySimplified Thanks for clearing that up. So its not describing the box itself.

[@PsychiatrySimplified]

Hammock first and then the box where they can escape. 👍

[@carolmiles7474]

Poor dogs ,they should not use dogs terrible😢

[@PsychiatrySimplified]

Yes its sad. Animals in general. The separation from mothers was heartbreaking

[@douglasman100]

how the fuck do you keep posting videos that explain the exact things i have spent a while thinking about. first it was hypoperfusion being connected to dopamine, now it's confirmation of this feeling that i have a messed up learning part of brain due to ptsd

[@PsychiatrySimplified]

Importantly as mentioned in the video, the activation of the hope circuit is possible. One can regain the perception of control. Wish you well.

[@syzygy4365]

​@@PsychiatrySimplifiedthrough therapy I guess, right? I really need to go.

[@Stopnormalizingviolence]

Selfish humans need to leave animals the fk alone! 🤬 One of my beagles is a laboratory survivor and she has canine PTSD from her time spent being tortured. These animals have feelings just like us and to willfully inflict harm onto innocent animals is sadistic and sick! The humans doing it are sadistic sociopaths with no empathy, no conscience, and the loooove hurting those precious little animals. Dangerous people! So many innocent animal lives damaged and wasted! It's not science, it's violence! All of humanity is getting worse and worse.